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Introduction of Reliability Test Technology for Electronics Package (전자패키지 신뢰성 평가기술의 개요)

  • Tanaka, Hirokazu;Kim, Keun-Soo
    • Journal of the Microelectronics and Packaging Society
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    • v.19 no.1
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    • pp.1-7
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    • 2012
  • Reliability technology has been expected to grow rapidly for new types of electronic equipments. We have selected several reliability issues in electronic package to be reviewed. This paper will provide a view of the current state of technological progress in reliability of electronic package in Japan, and will discuss future prospects for the technology.

Estimation of HCV Test in Diagnosis for Chronic Hepatitis C Virus (만성 C형 간염바이러스 진단에 있어서 HCV검사법의 평가)

  • Jang, Soon-Mo;Yang, Byoung Seon
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.3
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    • pp.261-266
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    • 2018
  • To determine the clinical utility of an immunoblot test and RT-PCR-hybridization test, 160 samples from patients with a chronic HCV infection were analyzed by two tests. A total of 133 samples out of 150 positive samples were positive by RT-PCR-hybridization. The true positive rate of the immunoblot tests and the concordance rate of the two tests was 88.6% and 89.3%, respectively. Serotyping and genotyping were performed to evaluate the distribution of the HCV subtype in Korean isolates. HCV serotypes 1 and 2, and genotypes 1b and 2a were the most common sources of HCV infections in this group. In 49 cases studied with the serotypes and genotypes, serotypes 1 and 2 were 57.1% and 42.9%, respectively. Genotypes 1b, 1b/2b, 2a, 2a/2c, and 2b were 51.0%, 2.0%, 34.7%, 8.2%, and 4.1%, respectively. This study shows that immunoblot tests are more useful for screening HCV infections. The RT-PCR-hybridization test confirmed the HCV infection in patients with positive immunoblot test results. The serotype test is preferred over the genotype test for monitoring the progression or response to treatment. On the other hand, there were no significant differences in the response to an ${\alpha}$-interferon treatment of HCV infection with serotype type 1 or type 2 in Korea.

Evaluation of PWHT cracking susceptibility of the Cr-Mo steel alloys (Cr-Mo 합금강의 후열처리 균열 감수성 평가)

  • Kim, Sang-Jin;Kim, Ki-Soo;Lee, Young-Ho
    • 대한공업교육학회지
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    • v.31 no.1
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    • pp.200-210
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    • 2006
  • This C-ring test, normally employed for evaluating susceptibility to stress-corrosion cracking, was determined to be a suitable small scale test to evaluate PWHT(Post-Weld Heat Treatment) cracking susceptibility. This test is possible to incorporate an actual weld, to introduce a notch into the coarse grained HAZ(Heat Affected Zone), to load the coarse grained HAZ any level of stress ad, most importantly, since the C-ring is an approximately constant strain type test, the stress decreases with time at temperature in a manner similar to that of an actual steel weldment. The procedure employed in making the C-ring was presented in the experimental procedure section, however, several points deserve further discussion. The walls of the weld groove are made along radial lines form the center of th var in order to obtain an HAZ which is oriented perpendicular to the walls of the machined C-ring. Therefore, the plane of maximum stress will be aligned through the HAZ and, therefore, crack propagation will not be forced to deviate form the plane of maximum stress in order to remain in the coarse grained HAZ as is the case with the Y groove test.

MUTAGENIC EVALUATION OF PRANOPROFEN, A NEW ANTI-INFLAMMATORY AGENT

  • Moon, Hwa-Hwey;Kim, Pu-Young;Yun, Tai-Bo;Jo, Dae-Hyun;Park, Han-Soo;Heo, Ok-Soon;Kim, Soon-Han;Choi, Suk-Hee
    • Toxicological Research
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    • v.3 no.1
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    • pp.15-26
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    • 1987
  • The mutagenicity of pranoprofen, a new antiinflammatory agent primarily used in Japan, was evaluated by employing several different methods such as the Ames test, micronucleus test, and the sister chromatid exchange test. For the Ames test, various doses of pranoprofen (5 and 1 mg, 100, 10, and 1 ${\mu}$g per plate) were applied, with or without the mammalian liver S-9 fraction, to the S. typhimurium LT2. For the micronucleus test, 24 hours after administering the various doses of pranoprofen (200, 100, and 50 mg/kg) to male mice by aral intubation, the femura of each group were isolated and the bone marrow samples were prepared. The micronucleated red cells and the ratio of the polychromatic versus the normochroomatic cells were counted. For the sister chromatid exchange test, the maximal non-cytotoxic concentrations (10 to 0.1 mM pranoprofen) were applied to the culture media of the Chinese Hamster Ovary (CHO) cells for 24 hrs. The numbers of revertant colonies did not increase with the increasing doses of pranoprofen when teseted with various strains of S. typhimurium. In the micronucleus test employing mice, the pranoprofen was identkfied to be a non-clastogen and a non-spindle poison. In the sister chromatid exchange test employing the cultured CHO cells, the pranoprofen did not increase the incidences of chromosomal abnormality. Based on these results, pranoprofen was found to have no mutagenic activity.

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Accelerated Life Analysis and Endurance Verification of Electro-Mechanical Actuator (항공기용 전기식 날개 구동장치의 가속 수명 분석 및 시험을 통한 내구성 검증)

  • Huh, Seok Haeng;Lee, Byung Ho;Seol, Jin Woon;Baek, Joo Hyun;Yang, Myung Seok;Kwon, Jun Young
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.10
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    • pp.829-835
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    • 2016
  • Electro-Mechanical Actuator installed on the aircraft plays a key role in an aircraft's flight control through flight control computer. Reliable prediction of the actuator is important for the aircraft. To estimate the lifetime of a product, it is necessary to test full target life. However, it is very difficult to perform it due to the long life time of actuator but short period of development time with increasing cost. Therefore, accelerated life test has been used to reduce the test time for various reasons such as reducing product's development cycle and cost. In this paper, to predict the lifetime of the actuator, we analyzed the flight profile of aircraft and adapted the method of accelerated life test in order to accelerate failure modes that might occur under user conditions. We also set up an endurance test equipment for validating the demanded lifetime of an actuator and performed accelerated life test.

Single Oral Dose-increasing Toxicity Test and Four Weeks Repeated Oral Dose Determinating Test of ACM (Added Chongmyung-tang) in Beagle Dogs (ACM의 비글견을 이용한 단회 경구투여 용량증가 독성 시험 및 4주 반복 경구투여 용량 결정 시험)

  • Lim, Jung-Hwa;Lee, Sang-Ryong;Jung, In-Chul
    • Journal of Oriental Neuropsychiatry
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    • v.24 no.1
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    • pp.131-144
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    • 2013
  • Objectives : To provide information on the safety of ACM, we carried out a single oral dose-increasing toxicity and 4-weeks repeated oral dose determining test of ACM in beagle dogs. Methods : In a single oral dose-increasing toxicity test, beagles were treated with ACM orally increasing dose level (1,000, 2,000, 5,000 mg/㎏) at interval of 3 days. After administration, signs of toxicity were observed for two weeks. In 4-weeks repeated oral dose determinating test, beagles were treated with ACM with oral dose 500, 1,000, 2,000 mg/kg for 4 weeks. Mortality, clinical signs, body weight changes, food consumption, urinalysis, hematological and biochemical parameters, organ weights, necropsy findings, and histological findings were monitored during the study period. Results : In a single oral dose-increasing toxicity test, we found no mortality, abnormalities in clinical signs, body weight, and necropsy findings during the study period. In 4-weeks repeated oral dose determinating test, we found no mortality, abnormalities in clinical signs, body weight, food consumption, urinalysis, hematological and biological parameters, gross findings, organ weights, necropsy findings, and histopathological findings in any of the beagles tested. Conclusions : The results obtained in these studies suggest that maximum tolerated dose (MTD) of ACM in male and female beagle dogs was supposed to be over 5,000 mg/kg. For the future studies of toxicity, it is advisable that high dose and low dose are set at 2000 mg/kg and 500 mg/kg, respectively.

Study on the Stability Test of Impinging(FOOF) Injector on $GN_2$ Purge Cold Flow Test (질소분사 음향시험을 통한 충돌형(FOOF) 분사기의 안정성 평가에 관한 연구)

  • Yoo Doc-Koon;Lee Kwang-Jin;Seo Seong-Hyeon;Han Young-Min;Choi Hwan-Seok;Seol Woo-Seok
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2006.05a
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    • pp.135-140
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    • 2006
  • In the experimental study of $N_2$ purge cold flow test of impinging(FOOF) injector for determining of instability region, the whistling sound which has a specific frequency is generated. The frequency of whistling is proportional to the gas flow velocity in part of the oxidizer orifice and due to the coupling of the vibrating gas column and the natural frequency of pipe-orifice shape, the discontinuous jumping phenomena arises. The whistling phenomena have no effect on the combustion instability. Compared the damping factor of 1T1L mode with the hot fire test, the instability region of $N_2$ purge cold flow test is very much like that. It means that flow instability by impinging or mixing of jet is the main reason of combustion instability of impinging injector(FOOF) in the hot firing test.

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Diagnostic Value of the Intradermal Test for the Infection with Clonorchis sinensis (간흡충증 진단을 위한 피내반응검사의 의의)

  • Kim, Jong-Ho;Yun, Bong-Yung;Lee, Heun-Ju;Lee, Hyun-Woo
    • Journal of Yeungnam Medical Science
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    • v.5 no.2
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    • pp.47-52
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    • 1988
  • The intradermal(ID) test has been widely used in Korea and several reports about the results of the ID test are known. We examined the egg of Clonorchis sinensis(C. s.) by ID test in 443, stool's egg-counting technique in 79 and direct smear(cellophane thick smear technique) in 1304 subjects. The results are as follows.: 1. The positive rate of C. s. was 3.8% out of 1304 persons. 2. The sensitivity of ID test was 82.1% out of 39 persons and, the specificity was 64.6% out of 404 persons. 3. The false positive of ID test 35.4% out of 404 persons and, the false negative was 17.9% out of 39 persons. Intradermal test is a rapid, sensitive and useful supplementary diagnostic tool for the detection of Clonorchiasis infection and must be used as screening test with direct smear of stool but cross reaction with other helminth infections and moderate false reaction are the main disadvantages in its practical application.

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Maintainability Improvement of Automatic Test Equipment for Aircraft (비행체 자동점검장비의 유지보수성 향상 방안)

  • Seo, Min-gi;Kwon, Ki-yong;Kim, Seong-woo;Lee, Seong-woo
    • Journal of Advanced Navigation Technology
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    • v.21 no.5
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    • pp.508-513
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    • 2017
  • Maintainability in engineering terms means ease of maintenance / management of the product. Aircraft automatic test equipment (ATE) is heavily influenced by the design changes of the unit under test(UUT) since the test procedure is developed according to the function / performance characteristics of the UUT. Moreover, if the integrated ATE is an environment that checks more than one UUT, it is not easy to maintain the ATE for the UUT design changes. Developers should be able to flexibly cope with the change of development staff by selecting an easy and clear development method to improve the maintainability of ATE. It is also necessary to limit the area affected by the UUT design change to a specific range to minimize the area to be modified. In this paper, we propose ATE development method which focuses on maintenance improvement based on the aircraft ATE development process.

Comparison of the Effects of Dynamic Postural Stability Training Versus Soft Ankle Bracing on Multiple Hop Performance in Participants With Functional Ankle Instability (기능적 발목 불안정성을 가진 대상자에게 동적 자세 안정성 훈련과 연성 발목 보조기가 다중 한발 뛰기 수행에 미치는 효과 비교)

  • Cha, Youn-sang;Park, Kyue-nam
    • Physical Therapy Korea
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    • v.24 no.1
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    • pp.1-8
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    • 2017
  • Background: The multiple hop test is an active performance test that has been commonly used to assess individuals with functional ankle instability. Previous studies have suggested that insufficiency of dynamic postural stability and passive stability during dynamic activities can have an influence on performance in the multiple hop test. However, no study has investigated the effects of dynamic postural stability training and ankle bracing on multiple hop test performance in individuals with functional ankle instability. Objects: The purpose of this study was to compare the immediate effects of dynamic postural stability training versus ankle bracing in the performance of the multiple hop test for participants with functional ankle instability. Methods: Twenty-nine participants with functional ankle instability who scored below 24 in the Cumberland Ankle Instability Tool were selected. The participants were randomly divided into two groups: a dynamic postural stability training group (n1=14) and an ankle bracing control group ($n_2=15$). The multiple hop tests were performed before and after applying each intervention. Dynamic postural stability training was performed using visual-feedback-based balance-training equipment; participants in this group were asked to perform a heel raise in a standing position while watching the centering of their forefoot pressure to prevent excessive ankle inversion. Ankle bracing was applied in the control group. Results: When comparing the pre- and post-intervention period for both groups, both methods significantly improved the results of the multiple hop test (p<.05). However, no significant differences were shown between the dynamic postural stability training and ankle bracing groups (p>.05). Conclusion: Both dynamic postural stability training and ankle bracing showed significant improvement (2.85 seconds and 2.05 seconds, respectively) in test performance. Further study is needed to determine the long-term effects of dynamic postural stability training and to determine whether insufficient dynamic postural stability is a causative factor for functional ankle instability.