• Title/Summary/Keyword: TER

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The Effect of Taeksa-tang for Dyslipidemia: A Systematic Review and Meta-Analysis (이상지질혈증에 대한 택사탕(澤瀉湯)의 효과 : 체계적 문헌 고찰 및 메타 분석)

  • Yeong-seo Lee;Tae-young Huh;Kyoung-min Kim
    • The Journal of Internal Korean Medicine
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    • v.44 no.3
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    • pp.485-505
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    • 2023
  • Objective: The purpose of this study is to assess the effectiveness and safety of using Taeksa-tang for dyslipidemia through a systematic review and meta-analysis of randomized controlled trials (RCTs). Methods: The search was conducted using keywords such as "dyslipidemia", "hyperlipidemia", "taeksa tang", "zexie tang", and "takusha to" in 12 databases (Pubmed, Cochrane, Embase, ScienceDirect, CNKI, Wanfang, CiNii, RISS, KISS, ScienceON, OASIS, and DBpia) on April 13, 2023. There were no limits on the publication period and language. Cochrane's risk of bias (RoB) was used to evaluate the quality of the studies. A meta-analysis was conducted according to the outcome measurements such as total effective rate (TER), total cholesterol (TC), triglyceride (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), and adverse effects, using the Review Manager web. Results: A total of 9 RCTs were selected. In evaluating the RoB, 2 studies mentioning the random sequence generation, 1 study conducting double blindness, and 8 studies without missing values were evaluated as low risk, while 1 study without mentioning the random sequence generation was evaluated as high risk. All other parts were evaluated as unclear risk. The treatment group (Taeksa-tang or Taeksa-tang-gagam) showed more statistically significant effects compared to the control group (Western medicine or Chinese patent medicine) in TER (RR : 1.24, 95% CI 1.15 to 1.34, P<0.00001), TC (MD : -1.12, 95% CI -1.68 to -0.56, P<0.0001), TG (MD : -1.08, 95% CI -1.65 to -0.51, P=0.0002), HDL-C (MD : 0.63, 95% CI 0.34 to 0.93, P<0.0001), LDL-C (MD : -0.81, 95% CI -1.10 to -0.53, P<0.00001). In addition, the treatment group showed lower adverse effects compared to the control group (RR : 0.30, 95% CI 0.12 to 0.74, P=0.008). Conclusion: This study suggests that Taeksa-tang is effective and safe to use for treating dyslipidemia. However, due to the low quality of the included studies, more clinical studies need to be conducted in the future to increase the possibility of clinical use.

Control Effects of Some Insecticides on Different Stages of the Stone Leek Leafminer, Liriomyza chinensis Kato (Diptera: Agromyzidae) (파굴파리의 충태별 약제방제 효과)

  • 최인후;장영석;김길하;김정화
    • Korean journal of applied entomology
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    • v.43 no.2
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    • pp.169-173
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    • 2004
  • Control effects of some insecticides were evaluated against the stone leek leafminer, Liriomyra chinensis Kato (Diptera: Agromyzidae) with the some different treatment methods. Insecticidal activities effects were estimated on the different development stages of the insects on welsh onion. The insecticides that controlled L. chinensis eggs with over 83% efficacy were spinosad, dimethoate, emamectin, and cartap. The insecticides that showed over 87% of larvicidal activity were dimethoate and cartap. Dimethoate showed 93.3% insecticide residual activity for 3 days a(ter treatment as a foliar spray. For control of pupae, the insecticides that showed over 88% of contact insecticidal activity were terbufos GR and cartap GR. Both dimethoate and cartap had high adulticidal activity with over 95% control efficacy.

Structure of Tetra-ter-butyl-tetrapropionyloxycalix[4]arene (Tetra-tert-butyl-tstrapropionyloxycalix [4] arene의 구조)

  • 김회진;노광현
    • Korean Journal of Crystallography
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    • v.4 no.1
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    • pp.25-35
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    • 1993
  • Tetra-tert-butyl-tetrapropionycalix (4) arena (C56H7208) is Triclinic, space group Pl, with a=13.664(5), b=17.585(5), c=12.863(2)A, a=109.33(2), B=111.97(2), γ=76.45(3) ˚, Z=2, V=2684.08A3, D, =1.152g/cm3, Dm=1.15g/cm3. The intensity data were collected on an Enraf-Nonius CAD-4 Diffractometer with a graphite monochromated Mo-Ka radiation. The structure was solved by direct methods and refined by leastsquares methods. The final R factor was 0.084 for 2561 observed reflections. The configuration of the molecule from the X-ray crystallographic investigation has the partial cone conformation, three tort-butylphenyls are down and a tort-butylphenyl is up. Three propionyloxy groups direct toward the exterior of the macrocycle cavity.

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A study of the systems of differentiate syndromes about apoplexy (중풍(中風)의 변증방법(辨證方法)에 대한 고찰(考察))

  • Sung Kang-Kyung;Yun Hyun-Ja
    • Herbal Formula Science
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    • v.6 no.1
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    • pp.285-291
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    • 1998
  • After looking into the systems of differentiate syndromes that referred in the Huang Di Nei Jung and the four authority of the Gum-Won dynasty which included the concept of the Myong-Chung dynasty's and the use of various symptoms occurred in clinical observation of apoplexy for material of differentiate syndromes, the result suggested as follows. 1. The system of differentiate syndromes is classified into interior and exterior beforeGum-Won dynasty. 2. In etiological (actors in apoplexy, the four authority of Gum-won dynasty insist on theendogenous theory. they compart the system of differentiate syndromes into apoplexy involving Jang Bu organs and blood vessels, but they did not escape from the system of interior and exterior. 3. The hallmark of exterior symptoms in apoplexy was the presence of syndromes in the six meridians, but in interior, constipation or difficulty in urination was the limitation. A(ter theprevious symptoms had been cured, tonifying therapy was used. 4. New concepts named Endogenous Wind SOTing In The Liver'and others in which oldsystems did not included was presented in Myong-Chung dynasty. 5. The old concept of the interior and exterior symptoms charactered with syndromes in thesix meridians, constipation and difficulty in urination can be replaced with internal andexternal symptoms. In old systems of differentiate symptoms in apoplexy, if replace interior and exteriorsymptoms with internal and external, we can include various differentiate configuration on thebasis of the conclusion. Because symptoms in apoplexy can be used in material of differentiate symptoms, I think that the prolongation of investigation is needed.

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Mechanisms of Russell's Viper Venom Toxicity on Renal Function; Reversal by Antivenom

  • Chaiyabutr, Narongsak;Napathorn, Sophon;Sitprija, Visith
    • Toxicological Research
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    • v.17
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    • pp.117-125
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    • 2001
  • Envenoming by Russells viper causes a broad spectrum of renal impairment. Renal failure is an important complication in patients bitten by Russells viper. Experimental work in animals and in vitro has elucidated pathophysiological mechanisms that contribute to life threatening complications and have suggested possibilities for therapeutic intervention. The evidence in experimental animals regarding mechanisms of venom action in relation to changes in either extrarenal or intrarenal factors is presented. The cardiovascular system and renal hemodynamics are affected by venom. Reductions of renal function including renal hemodynamics are associated directly with changes in general circulation during envenomation. Possible endogenous mechanisms for releasing the hormone inducing renal vasoconstriction after envenomation are evident. Hormonal factor such as the catecholamine, prostaglandin and renin angiotensin systems induce these changes. Direct nephrotoxicity of venom action is studied in the isolated per-fused kidney. Characteristic polarization of the cell membrane, changes of mitochondrial activity and Na-K ATPase in renal tubular cells are observed. Changes in renal function and the cardiovascular system are observed of ter envenomation and are reversed by the administration of Russells viper antivenom (purified equine immunoglobulin, $Fab_2$ fragment). The neutralizing effects are more efficient when the intravenous injection of antivenom is given within 30 min after the envenomation.

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Study on high performance cathode on YSZ electrolyte for intermediate-temperature solid oxide fuel cells(IT-SOFC) (중온형 고체산화물 연료전지를 위한 YSZ 전해질에서의 고성능 공기극 연구)

  • Lee, Chang-Bo;Bae, Joong-Myeon
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.11a
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    • pp.368-371
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    • 2006
  • [ $La_{0.8}Sr_{0.2}Co_{1-x}Mn_xO_3$ ] cathode as a high performance cathode on YSZ electrolyte was studied by analyzing impedance spectra. It was shown that cathode property of $La_{0.8}Sr_{0.2}Co_{1-x}Mn_xO_3$ is bet ter than that of$La_{0.8}Sr_{0.2}CoO_3$. At $700^{\circ}C$ in air environment, $La_{0.8}Sr_{0.2}Co_{0.4}Mn_{0.6}O_3$ cathode on CGO- layered YSZ electrolyte showed very low area specific resistance of $0.14{\Omega}cm^2$, which is low enough for intermediate-temperature sol id oxide fuel cells. This is because material properties of ionic conductivity and thermal expansion compatibility with electrolyte were optimized. Judging from activation energy and oxygen part i al pressure dependance of cathode property, it was noted that oxygen surface exchange kinetics is dominantly influential on cathode property in higher temperature region than $700^{\circ}C$ and oxygen self-diffusion in cathode material is more influential in lower temperature region.

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A Study on the Reverse Cleaning Flow Characteristics for High Temperature and High Pressure Filtration (고온 고압 집진을 위한 역세정 유동장의 특성에 관한 연구)

  • 김장우;정진도;김은권
    • Journal of Korean Society for Atmospheric Environment
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    • v.19 no.1
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    • pp.25-31
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    • 2003
  • Ceramic filter has been demonstrated as an attractive system to improve the thermal efficiency and to reduce the effluent pollutants. Removal of particulates from the hot gas stream is very important in air pollution control. In particular, the elimination of the particulate matters discharged from a gas turbine at high temperature can prevent the corrosion inside the IGCC. In this study, a Lab. scale test and numerical simulation were carried out to comprehend the relationship between pulse jet pressure and recovery of pressure drop and to characterize the reverse cleaning flow through a ceramic fil-ter element under high temperature and high pressure. When the pulse-jet pressures were 2, 3 and 4 kg/$ extrm{cm}^2$, the cleaning effect increase of about 10~30% by recovery of pressure drop caused by pulse pressure. Cleaning effect at 45$0^{\circ}C$ was greater than that at 55$0^{\circ}C$ or 650$^{\circ}$ for the same pulse pressure. According to the result of the present simulation, high pressure has been formed in terminal and central regions in our models and temperature distribution caused by pulse air is to be uniform comparatively on inner surface of filter.

Controlled Crystallization and its Effects on Some Properties of Ge-Se-Te Chalcogenide Glass (Ge-Se-Te계 Chalcogenide 유리의 결정화 및 결정화가 물성에 미치는 영향)

  • 송순모;최세영;이용근
    • Journal of the Korean Ceramic Society
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    • v.33 no.8
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    • pp.855-862
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    • 1996
  • The nucleation and the crystal growth rates of Ge-Se-Te chalcogenide glass by two step heat-treatment and its effect on the mechanical optical properties and water-resistance were determined. The maximum nuclea-tion and crystal growth rate were 2.1$\times$103/mm3 .min at 28$0^{\circ}C$ and 0.4${\mu}{\textrm}{m}$/min at 33$0^{\circ}C$ respectively. When the crystal volume fraction with crystal size $1.5mutextrm{m}$ was about 4% the (hardness and fracture toughness were about 117kg/mm2 and 6.0 MPa.mm1/2)respectively. The weight loss of crystallized glass in water was lower than parent glass($25^{\circ}C$ for 32 hrs : 0.03% 8$0^{\circ}C$ for 16 hrs : 0.1%) as 0.01% at $25^{\circ}C$, 0.03% at 8$0^{\circ}C$ for 16 hrs : 0.1%) at $25^{\circ}C$ 0.03% at 8$0^{\circ}C$ respectively. The IR-transmittance decreased with increasing crystal size and crystal volume fraction. The IR-transmittance of crystallized glass with the crystal size of $1.5mutextrm{m}$ (crystal volume fraction : 4%) presented 56% which was about 4% lower than that of parent glass.

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Preparation and Characterization of $TiO_2$ Membranes for Microfiltration ($TiO_2$ 정밀여과막의 제조 및 특성)

  • 한상욱;최세영;현상훈;조철구;강한규
    • Journal of the Korean Ceramic Society
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    • v.33 no.6
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    • pp.700-708
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    • 1996
  • TiO2 membranes for microfiltration were prepared on $\alpha$-alumina support tube by slurry coating. The coating layer was obtained by flowing TiO2 slip on the inner surface of the alumina support. TiO2 membranes were heat-treated at 9$25^{\circ}C$ for 2 hrs. The thickness of the unsupported membrane was about 10${\mu}{\textrm}{m}$. The mean pore diameter of the membranes were 0.09 and 0.15${\mu}{\textrm}{m}$ respectively and the pure water flux was 900~1,200ι/m2.hr at room temperature and 1 bar. For a possible application of oily wastewater treatement an kerosene/wa-ter emulsion was separated in terms of flux and removal efficiency. In 60 min of operating time the flux of TiO2 membranes was 50~100 ι/m2.hr and removal efficiency was over 97% at 3kgf/cm2 of operating pres-sure and 600 ml/min of flow rate. TiO2 membranes could be recycled by reheat treatments at $600^{\circ}C$ for 2 hrs.

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Effects of Ganoderma lucidum on Lipid Metabolism in Dietary Hypercholesterolemic Rats (영지 열수추출액이 식이성 고콜레스테롤 혈증 흰쥐의 지질대사에 미치는 영향)

  • 정승용;김성애;김성희;김한수;김군자;김희숙;정효숙
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.19 no.2
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    • pp.180-186
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    • 1990
  • For the investigation of the effects of G. lucidum on prevention and attention of hypercholeste-rolemia and atherosclerosis dietary hypercholesterolemic rats were fed with 2.0g% G. lucidum extracts for 4 weeks. And then concentrations of total cholesterol triglyceride phospholipid in serum and liver and those of HDL-cholesterol lipid peroxide glucose in serum were analyzed. Concentration of total cholesterol in serum was the lowest in the control group(basal diet+ wa-ter) and HDL-cholesterol in serum were significantly higher in groups of control 2(hyperchole-sterolemic ratslongrightarrowbasal+water) and 4(hypercholesterolemic ratslongrightarrowbasal+G.l. extract) The concentration of triglyceride in serum were signficantly lower in groups 4 and 5(hypercholeste-rolemic ratslongrightarrowcholesterol+G. l. extract) than in the control group. Phospholipid content in serum were not significantly different among all groups. Ttal cholesterol in liver was significa-ntly higher in hypercholesterolemic rats than in the control group and triglyceride concentration were signficantly higher in groups of 3(hypercholesterolemic ratslongrightarrowcholesterol+water) and 5 than others. Phospholipid in liver was significantly higher in group 3 than in the control group but groups of 4 and 5 were lower. As for lipid peroxide in serum was the lowest in group 4 and glucose concentration was lowest in group 5 than in other groups.

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