• 제목/요약/키워드: TDI

검색결과 219건 처리시간 0.024초

Impact of anthropogenic activities on the accumulation of heavy metals in water, sediments and some commercially important fish of the Padma River, Bangladesh

  • M Golam Mortuza
    • Fisheries and Aquatic Sciences
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    • 제27권2호
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    • pp.66-75
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    • 2024
  • Heavy metals are naturally found in the ecosystem, and their presence in the freshwater river is increasing through anthropogenic activities which pose a threat to living beings. In this study, heavy metal concentrations (Zn, Mn, Cu, Cd, Cu, Cr, Pb, and Ni) in different organs (muscle, skin, and gill) of fish from the Padma River were evaluated to quantify, and compare the contamination levels and related human health risks. The results revealed that the heavy metal concentrations in the water, surface sediments, and fish taken from the Padma River were far below the WHO/USEPA's permitted limits. The estimated daily intake (EDI) value in muscle was less than the tolerable daily intake (TDI). The target hazard quotient (THQ) and hazard indexes (HI) were less than 1, showing that consumers face no non-carcinogenic risk (CR). CR values of Cu, Cd, Cr, Pb, and Ni ranged from 4.00 × 10-8 to 6.35 × 10-6, less than 10-4, and total carcinogenic risk (CRt) values ranged from 9.85 × 10-6 to 1.10 × 10-5, indicating some pose a CR from consumption of those fish from the Padma River. To establish a more accurate risk assessment, numerous exposure routes, including inhalation and cutaneous exposure, should be explored.

위성카메라 전자부의 화소간 응답불균일성 보정계수의 비교검토 (Comparison of Correction Coefficients for the Non-uniformity of Pixel Response in Satellite Camera Electronics)

  • 공종필;이성재
    • 대한원격탐사학회지
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    • 제27권2호
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    • pp.89-98
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    • 2011
  • 위성 카메라전자부의 화소간 불균일성 응답의 보정을 위한 4종류의 이득과 오프셋 보정계수에 대하여 다루었다. 이들에 대한 비교분석을 위해서 CCD를 광검출기로 하는 카메라전자부를 새롭게 제작하고, 이를 이용하여 얻은 영상 데이터에 대하여 이들 4종의 보정계수를 이용하여 보정을 실행한 후 각각의 보정 성능을 비교하였다. 일반적으로 보정성능은 기준 영상을 얻기 위하여 사용된 빛입력 레벨의 개수에 따라 달라지게 된다. 쉽게 예상될 수 있는 바와 같이, 2 레벨의 빛입력 기준영상만을 이용하여 얻은 보정계수의 경우 보정계수를 계산하기가 쉽다는 이점을 갖고 있지만, 보정성능은 상대적으로 떨어진다는 것을 확인할 수 있었다. 이에 비해 보정계수를 구하기 위하여 사용된 기준영상의 빛입력 레벨의 개수가 2보다 큰 값으로 늘어날 경우, 보정성능은 개선되었다. 하지만 각각의 보정계수들간의 보정성능 상에는 큰 차이가 없는 것으로 평가되었다.

BrdU ELISA를 이용한 국소 림프절 시험법의 비방사선법 연구 (A Non-radioisotopic Endpoint Using Bromodeoxyuridine ELISA Method for Murine Local Lymph Node Assay)

  • 이종권;박재현;박승희;김형수;정승태;엄준호;윤소미;장은정;최광식
    • Toxicological Research
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    • 제19권2호
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    • pp.133-139
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    • 2003
  • Allergic contact dermatitis may be caused by a wide variety of chemicals. A murine local lymph node assay (LLNA) has been developed as an alternative to guinea pig models for assessing the contact sensitization potential of chemical. However, there is a need to develop a nonradioisotopic endpoint for the LLNA, because of the radioisotopic method's requiring the use of special facilities. In this study, we investigated the development of a nonradioisotopic endpoint for LLNA using ELISA (enzyme-linked immunosorbent assay). Female Balb/c mice were treated by the topical application on the dorsum of both ears with four different strong sensitizers, 2,4-dinitrochlorobenzene (DNCB), oxazolone (OXZ), toluene diisocyanate (TDI), and trimellitic anhydride (TMA), and a strong irritant, sodium lauryl sulfate (SLS), once daily for three consecutive days. The proliferation of cells in the auricular Iymph node was analyzed by means of the labelling index (Ll) of bromodeoxyuridine (BrdU) incorporation into cells. The weights of the Iymph nodes in the mice treated with allergens, DNCB, OXZ, TDl and TMA were increased compared to the vehicle control. The stimulation index (Sl) of mice treated with DNCB, OXZ, TDl, and TMA was over three-fold increase compared to the vehicle control. However, the S1 of mice exposed to SLS was not significantly increased compared to the vehicle control, while the lymph node weight of SLS was significantly increased. These results suggest that the LLNA modified endpoint using ELISA based on BrdU incorporation could provide a useful method of screening for irritants and allergens.

Dietary Intake and Potential Health Risk of Polycyclic Aromatic Hydrocarbons (PAHs) via Various Marine Organisms in Korea

  • Moon Hyo-Bang;Lee Su-Jeong;Park Jong-Soo
    • Fisheries and Aquatic Sciences
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    • 제7권3호
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    • pp.141-147
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    • 2004
  • Sixteen polycyclic aromatic hydrocarbons (PAHs) were analyzed in seventy marine organisms (40 species) from the Korean coast. PAHs were present in all the organisms. The level of total PAHs in the organisms varied from 0.45 to 224 ng/g dry weight and the carcinogenic PAHs varied from 0.05 to 49.8 ng/g dry weight. The PAHs residues according to the marine organisms showed a highest content in bivalve species, and followed by crustaceans, cephalopods, fish and gastropods. Human dietary intake of total PAHs through marine organism in Korea was estimated to be 4.12 ng/kg body weight/day and 0.67 ng/kg body weight/day for carcinogenic PAHs. The relative contributions of individual species to the total dietary intake of PAHs were in the order of bivalves $(53.4{\%})$, fish $(21.9{\%})$, crustaceans $(15.3{\%})$, cephalopods $(8.8{\%})$ and gastropods $(0.6{\%})$. Daily dietary intake of $PAH_{TEQ}$ expressed as a TEQ value was estimated to be 0.13 pg TEQ/kg body weight/day, which did not exceed a tolerable daily intake (TDI) proposed by the KFDA and the WHO as well as the UK toxicity committee. Lifetime cancer risk due to ingestion of marine species by the Korean adult was evaluated using the equation estimating exposure of food ingestion. Although approximately $23{\%}$ of cumulative frequency of the sampled marine species exceeded the cancer risk guideline, lifetime cancer risk associated with marine organism consumption was negligible. Results indicate that dietary intake of PAHs through the consumption of the Korean marine organisms seems to be safe for human ingestion with negligible cancer risk.

Estimation of dietary intake and human health risk of hexachlorobenzene by marine organism consumption in Korea

  • Moon Hyo-Bang;Lee Su-Jeong;Lee Yoon;Park Jong-Soo
    • 한국환경과학회지
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    • 제14권2호
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    • pp.121-128
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    • 2005
  • Hexachlorobenzene (HCB) was analyzed in various marine organisms of Korea. HCB was detected in all organism samples with residual concentrations from 0.51 to 222 pg/g wet weight. HCB residue was the highest content in crustacean, and followed by bivalves, fish, cephalopods and gastropods. The residues were comparable to or lower than those in marine organisms of other countries. Daily dietary intake of HCB from seafood was estimated to be 13.4 pg/kg body weight/day. The relative contribution of taxonomic group to the total dietary intake of HCB were in the order of crustaceans $(40.1\%)$, bivalves $(34.2\%)$, fish $(23.1\%)$, cephalopods $(2.22\%)$, and gastropods $(0.38\%)$. Daily dietary intake of HCB expressed as toxic equivalent (TEQ) value was estimated to be $1.34\times10^{-3}pg$ TEQ/kg body weight/day. This value did not exceed tolerable daily intake (TDI) proposed by the WHO, the UK toxicity committee and the KFDA. Cancer risk and target hazard quotient (THQ) due to the consumption of the marine organism in Korean adult population were evaluated using the exposure equation of food ingestion. This result suggests that dietary intake of HCB by the consumption of Korean seafood seems to be safe for human health with negligible cancer and non-cancer risks so far.

Preparation and Application of Polyurethane-urea Microcapsules Containing Phase Change Materials

  • Kwon Ji-Yun;Kim Han-Do
    • Fibers and Polymers
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    • 제7권1호
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    • pp.12-19
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    • 2006
  • For thermal adaptable fabrics, the polyurethane-urea microcapsules containing phase-change materials (PCMs: hexadecane, octadecane and eicosane) were successfully synthesized by interfacial polycondensation using 2,4-toluene diisocyanate (TDI)/poly(ethylene glycol) (PEG400)/ethylene diamine (EDA) as shell monomers and nonionic surfactant NP-12 in an emulsion system under stirring rates of $3,000{\sim}13,000$ rpm. The mean particle size of microcapsule decreased significantly with increasing the stirring rate up to 11,000 rpm, and then leveled off. The mean particle size increased with increasing the content and molecular weight (eicosane > octadecane > hexadecane) of PCMs at the same stirring rate. The mean particle sizes of microcapsules were found to decrease with increasing the NP-12 content up to 1.5 wt%, and thereafter increased a little. It was found that the melting temperature ($T_m$) and crystallization temperature ($T_c$) of three kinds of encapsulated PCMs and their enthalpy changes (${\Delta}H_m,{\Delta}H_c$) increased with increasing PCM contents. The encapsulation efficiencies (Ee) of hexadecane microcapsule linearly increased with increasing the content of hexadecane. It was found that the stable microcapsule containing 50 wt% of hexadecane could be obtained in this study. However, Ee of octadecane and eicosane microcapsules increased with increasing PCM's contents up to 40 wt%, and then decreased a little. By considering the encapsulation efficiency, it was found that the maximum/optimum contents of octadecane and eicosane microcapsules were about 40 wt%. By the dynamic thermal performance test, it was found that the maximum buffering levels of Nylon fabrics coated with hexadecane, octadecane, and eicosane microcapsules were about $-2.4/+2.9^{\circ}C,\;-3.6/+3.6^{\circ}C\;and\;-4.0/+4.7^{\circ}C$, respectively.

코리안 숏헤어 고양이의 제한성 심근병증 (Restrictive Cardiomyopathy in a Korean Domestic Short-haired Cat)

  • 남효승;한숙희;최란;이승곤;현창백
    • 한국임상수의학회지
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    • 제29권3호
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    • pp.242-246
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    • 2012
  • 3살된 코리안 숏헤어 고양이(몸무게 5.2 kg)가 복수, 흉수, 호흡곤란으로 인해 강원대학교 수의과대학병원에 진료의뢰 되었다. 진단검사상, 유미성 흉수와 출혈성 복수, 심장비대, PW 도플러 초음파와 TDI 초음파의 restrictive filling pattern, 미비하게 비대된 좌심실 자유벽이 관찰되었다. 심장초음파 진단소견을 토대로 제한성 심근병증으로 잠정진단 내리게 되었다. 본 환자는 흉수를 제거하고 furosemide, enalapril, sildenafil, clopidogrel을 포함한 약물치료를 하였다. 이것은 국내에서 처음으로 발표하는 제한성 심근병증의 증례이다.

충남 예당저수지를 포함한 10개 저수지의 영양단계 및 부착규조지수를 이용한 수질평가 (Water Quality Assessment using Trophic Status Index and Attached Diatom Index in 10 Reservoirs including Ye-dang Reservoir of Chungcheongnam-do)

  • 송미애;김지원;김헌년;공동수;이옥민
    • 생태와환경
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    • 제44권2호
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    • pp.155-171
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    • 2011
  • The research assessed water quality using physico-chemical factors, trophic status index and attached diatom index in 10 reservoirs located in Chungcheongnam-do from October 2007 to June 2008. The physico-chemical water quality assessments revealed that Dangjin-gun (St. 1~5), which displayed a high chemical oxygen demand (V and VI) and chlorophyll-${\alpha}$ (Eutrophic-Hypereutrophic), was more polluted than Yesan and Cheongyang-gun. The sample were also hypereutrophic [trophic status index (TSI) 74.6] and ${\beta}$-mesosaprobic [diatom assemblage index to the organic water pollution (DAIpo) 44.47]. Yesan and Cheongyang-gun. Which were mid-level in their pollution status, were eutrophic (TSI 56.9) and ${\alpha}$-oligosaprobic (DAIpo 60.11). TSI correlated strongly with the attached diatom index (of DAIpo 0.60~0.62, and trophic diatom index of 0.72~0.74). Hence, the attached diatom index can be used with the trophic status assessment of lakes using TSI, and lake trophic status index (LTSI).

임베디드 LINUX 시스템 기반 USB 카메라 인터페이스 구현 (Implementation of an USB Camera Interface Based on Embedded Linux System)

  • 송성희;김정현;김태효
    • 융합신호처리학회논문지
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    • 제6권4호
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    • pp.169-175
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    • 2005
  • 최근 국내외에서 임베디드 시스템 구현에 관한 많은 관심과 개발 경쟁이 한층 심화되고 있다. 지금까지 실시간으로 임베디드 영상획득 및 처리시스템을 구축하는 데에는 현실적 제한이 많았다. 따라서 본 논문에서는 임베디드 LINUX 시스템에 저가의 USH2.0카메라를 이용하여 USB Camera 인터페이스 시스템을 구현하였다. Host2.0 TDI 보드의 디바이스 드라이버를 커널에 탑재하여 USB카메라에서 들어오는 영상 신호를 X-hyper255B로 입력하게 된다. 커널의 디바이스 관리에서 Video4Linux를 이용하여 USB카메라에 대한 정보의 초기 설정이 필요하다. 이렇게 구현한 시스템에서 영상을 획득하고 영상 신호처리를 하게 된다. 처리된 영상 데이터는 네트워크 파일 시스템(NFS)으로 패킷화되어 인터넷으로 전송되고, 인터넷이 접속된 클라이언트 컴퓨터에서 전송된 영상정보를 모니터링 할 수 있음을 확인하였다.

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Synthesis of Novel Polythiol for Plastic Optical Lens and its Ophthalmic Lens

  • Jang, Dong-Gyu;Roh, Soo-Gyun;Kim, Jong-Hyo;Jin, Wen-Yi;Seo, Jin-Moo;Kwon, Myeong-Ja;Lee, Soo-Min
    • Bulletin of the Korean Chemical Society
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    • 제30권10호
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    • pp.2227-2232
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    • 2009
  • Novel polythiol materials of urethane lens series for plastic optical lens were synthesized from polyol materials via thioisouronium of thiourea with c-HCl in refluxing aqueous solution, in which polythiol material was carried out from hydrolysis of thioisouronium by ammonia water. Their structure properties were identified by EA, EI-MS, FT-IR, $^1H\;and\;^{13}C$ NMR spectroscopies and TGA. Their ophthalmic lenses as polythiourethane material were prepared by thermal curing to an injected glass mold using the evenly solutions of diisocyanates series (TDI, XDI, HDI or IPDI) with polythiols. Polythiourethane shows that the strong stretching mode for SH group of polythiol disappeared in FT-IR spectra after thermosetting polymerization. Thermal deformation starting temperature of ophthalmic lenses was determined by TMA. Ophthalmic lenses made from characteristic polythiol and diisocyanate series have transparency, colorless and good impact strength, in which thermal resistance and impact strength of ophthalmic lenses were influenced by diisocyanate series. Physical properties of ophthalmic lens have contrast thermal resistance with impact strength. The property of thermal resistance and impact strength for respective ophthalmic lenses was examined by TMA and drop ball test.