• 한국식품위생안전성학회지
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• 제17권3호
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• pp.137-145
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• 2002

국내 6개 주요도시에서 조사된 어패류 오염도 현황을 토대로 우리나라 사람들의 어패류 섭취를 통한 유기주석화합물 인체노출량을 예측하고, 이에 따른 위해도를 추계하였다. 본 연구결과를 살펴보면 갈치의 경우, 성인이 식품수급표에서 제시하는 일일섭취량 3.02g/day를 평생 섭취한다는 노출시나리오하에 평균일일노출량은 확률분포로 나타냈을 때 그 중간값이 6.48$\times$ $10^{-7}$ mg/kg/day, 상한치 95th percentile값이 8.78$\times$$10^{-7}$ mg/kg/day로 나타났음을 알 수 있다. 본 연구에서는 비발암독성영향을 평가하기 위하여 BMD$_{10}$ 을 활용한 참고치(Reference dose)를 예측하였다. 이 때 BMD$_{10}$은 10% 비교변화를 BMR으로 하였을때 해당하는 용량의 95% 하한치이다. 본 연구에서 활용한 BMD는 digestion에 의한 근육내의 IgE titer, T.spiraris larvae와 조직학에 의한 근육내 T.spiraris larvae에 근거하여 예측된 것으로 0.03 mg/kg/day이다. 참고치는 BMD$_{10}$ 0.03 mg/kg/day에 불확실성 계수 100을 고려한 값으로 0.003 mg/kg/day이며, 이 때 활용한 불확실성계수는 실험동물에서 인체로의 외삽과정에서 고려한 계수 10과 인구집단 내 민감그룹 고려를 위한 계수 10을 적용한 것이다. 각 어패류의 위험지수(50th percentile)를 살펴보면 고등어에서 2.04$\times$ $10^{-2}$으로 가장 높게 나타났으며, 소라에서 2.70$\times$ $10^{-5}$으로 가장 낮은 값을 나타냈다.

• Tuberculosis and Respiratory Diseases
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• 제84권2호
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• pp.96-104
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• 2021

Background: Many chronic obstructive pulmonary disease (COPD) patients receiving monotherapy continue to experience symptoms, exacerbations and poor quality of life. This study aimed to assess the efficacy and safety of direct switch from once-daily tiotropium (TIO) 18 ㎍ to indacaterol/glycopyrronium (IND/GLY) 110/50 ㎍ once daily in COPD patients in Korea. Methods: This was a randomized, open-label, parallel group, 12-week trial in mild-to-moderate COPD patients who received TIO 18 ㎍ once daily for ≥12 weeks prior to study initiation. Patients aged ≥40 years, with predicted post-bronchodilator forced expiratory volume in 1 second (FEV₁) ≥50%, post-bronchodilator FEV₁/forced vital capacity <0.7 and smoking history of ≥10 pack-years were included. Eligible patients were randomized in a 1:1 ratio to either IND/GLY or TIO. The primary objective was to demonstrate superiority of IND/GLY over TIO in pre-dose trough FEV₁ at week 12. Secondary endpoints included transition dyspnea index (TDI) focal score, COPD assessment test (CAT) total score, and rescue medication use following the 12-week treatment, and safety assessment. Results: Of the 442 patients screened, 379 were randomized and 347 completed the study. IND/GLY demonstrated superiority in pre-dose trough FEV₁ versus TIO at week 12 (least squares mean treatment difference [Δ], 50 mL; p=0.013). Also, numerical improvements were observed with IND/GLY in the TDI focal score (Δ, 0.31), CAT total score (Δ, -0.81), and rescue medication use (Δ, -0.09 puffs/day). Both treatments were well tolerated by patients. Conclusion: A direct switch from TIO to IND/GLY provided improvements in lung function and other patient-reported outcomes with an acceptable safety profile in patients with mild-to-moderate airflow limitation.

• Elastomers and Composites
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• 제52권4호
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• pp.266-271
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• 2017

This study describes the influence of the amount of curing agent and curing temperature on the kinetics of polyurethane elastomers. The urethane prepolymer series was prepared by reacting toluene diisocyanate with polytetramethylene ether glycol at $80^{\circ}C$ for 1 h, and 4,4'-methylene bis(2-chloroaniline) was used as the curing agent. The ratio of the amine group of the curing agent to the isocyanate group of the urethane prepolymer was controlled from 0.85 to 1.05 at curing temperatures ranging from 80 to $120^{\circ}C$. The curing rate of the urethane prepolymer was monitored by observing the change in heat flow during the curing process using differential scanning calorimetry (DSC). As either the content of curing agent or the curing temperature was higher, the conversion rate to the polyurethane elastomer was high. The DSC results were compared with those obtained from using real-time FT-IR.

• 대한원격탐사학회지
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• 제32권4호
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• pp.339-351
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• 2016

For the safety of sea, it is important to monitor sea fog, one of the dangerous meteorological phenomena which cause marine accidents. To detect and monitor sea fog, Moderate Resolution Imaging Spectroradiometer (MODIS) data which is capable to provide spatial distribution of sea fog has been used. The previous automatic sea fog detection algorithms were focused on detecting sea fog using Terra/MODIS only. The improved algorithm is based on the sea fog detection algorithm by Wu and Li (2014) and it is applicable to both Terra and Aqua MODIS data. We have focused on detecting spring season sea fog events in the Yellow Sea. The algorithm includes application of cloud mask product, the Normalized Difference Snow Index (NDSI), the STandard Deviation test using infrared channel ($STD_{IR}$) with various window size, Temperature Difference Index(TDI) in the algorithm (BTCT - SST) and Normalized Water Vapor Index (NWVI). Through the calculation of the Hanssen-Kuiper Skill Score (KSS) using sea fog manual detection result, we derived more suitable threshold for each index. The adjusted threshold is expected to bring higher accuracy of sea fog detection for spring season daytime sea fog detection using MODIS in the Yellow Sea.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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• pp.633-636
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• 2005

An electro-optical camera system consists of many subsystems such as the optics, the detector, and the electronics and so on. They may create variations in the processed image that were not present original scene. The performance analysis of the electro-optical camera system is a mathematical construct that provides an optimum design through appropriate trade off analysis. The SNR(Signal to Noise Ratio) is one of the most important performance for the electro-optical camera system. The SNR analysis shown in this paper is performed based on the practical high resolution satellite camera design. For the purpose of the practical camera design, the analysis assumes that the defined radiance, which is calculated for the Korean peninsula, reached directly to the telescope entrance. In addition, the actual operation concept such as integration time and the normal operation altitude is assumed. This paper compares the SNR analysis results according to the various camera characteristics such as the optics, the detector, and the camera electronics. In detail, the optical characteristics can be split into the focal length, F#, transmittance, and so on. And the system responsivity, the quantum efficiency, the TDI stages, the quantization noise and the analogue noise can be used for the detector and the camera electronics characteristics. Finally this paper suggests the optimum design to apply the practical electro-optical system.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2004년도 Proceedings of ISRS 2004
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• pp.601-603
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• 2004

Multi-Spectral Camera(MSC) is a payload on the KOMPSAT -2 satellite to perform the earth remote sensing. The instrument images the earth using a push-broom motion with a swath width of 15 km and a ground sample distance (GSD) of 1 m over the entire field of view (FOV) at altitude 685 Km. The instrument is designed to have an on-orbit operation duty cycle of $20\%$ over the mission lifetime of 3 years with the functions of programmable gain! offset and onboard image data compression/storage. MSC instrument has one(1) channel for panchromatic Imaging and four(4) channel for multi-spectral Imaging covering the spectral range from 450nm to 900nm using TDI CCD Focal Plane Array (FPA). In this paper, the configuration, the interface of MSC hardware and the MSC operation concept are described. And the method of the MSC calibration are described and the design of MSC calibration operation to measure the change of MSC after Launch & Early Operation(LEOP) and normal mission operations are discussed and analyzed.

• 한국패류학회지
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• 제25권1호
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• pp.35-40
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• 2009

The trumpet shell Charonia sauliae is an endangered and valuable species with potential for aquaculture. For artificial propagation of C. sauliae, the effects of three different food microalgae on the development, growth, and survival rate of the larvae and spat were investigated. For the larval feeding experiments, we utilized six microalgae species as food sources, namely Pavlova lutheri, Tetraselmis suecica, Nannochloris oculata, Isochrysis galbana, Chaetoceros calcitrans, and Phaeodactylum tricornutum; for the larval and spat growth and survival experiments, we utilized T. suecica, C. calcitrans, and P. tricornutum. The results showed that the temporal digestion index (TDI) for the veliger larvae was significantly different for C. sauliae fed the different microalgae species (p < 0.05), that the T. suecica, C. calcitrans, and P. tricornutum cultivars were better suited for larval consumption (p < 0.05), and that the growth and survival of the larvae and spat were significantly influenced by food type, specifically P. tricornutum (p < 0.05). Further research is needed to evaluate the effects of other microalgae species, different algal concentrations, and biochemical composition on the growth and survival of C. sauliae.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 추계학술대회 논문집
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• pp.1566-1573
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• 2007

Urban railway system that leads the urban public transportation enables the passengers to use the subway system safely and conveniently by indicating the destination of, status of approach of and other information on train through Train Destination Equipment(TDE), which is one of the important passenger services. The existing system is composed of Host Station Equipment(HSE) and operator panel that receives necessary input on train information from Total Traffic Control System(TTC), Local Station Equipment(LSE) that controls Train Destination Indicator(TDI) installed at each station, and Train Destination Indicator that ultimately displays train information to the passengers using the train system. This study aims to realize stabilized and reliable announcement system for destination of train by considering processing procedure and method of expression of inputted information of the existing system of notification of announcement of destination of train that can be applied in the RFID, which is the base technology of USN for which service expansion is easy, and to realize system that considers interface with USN and expandability with other facilities in the future.

• 한국물환경학회지
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• 제30권6호
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• pp.612-621
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• 2014

Physicochemical factors and the phytoplankton communities in the downstream area of Namhan-River were investigated from June 2012 to November 2013. We also assessed water quality using biological water quality indices. Total nitrogen was 2.4 mg/L, total phosphorus was 0.04 mg/L, and biological oxygen demand was 1.1 mg/L. This resulted in a level 2 (Ib, good) water quality rating. A total of 259 phytoplankton taxa were classified, consisting of 26 families, two subfamilies, 64 genera, 222 species, 32 varieties, and five formas. Bacillariophyceae dominated during a1l seasons and at all sites. The dominant species were Aulacoseira granulata, Cyclotella meneghiniana, C. stelligera, Melosira varians, Cocconeis placentula var. lineata, Nitzschia palea, N. amphibia, Cymbella minuta, and Achnanthes convergens. The diatom assemblage index for organic pollution values was level A-D, and TDI was level B-D. P-IBI at most sites was at the M (moderate) level, but TSI was at the E (eutrophic) level. Most indices dropped from upstream to downstream.

• 한국응용과학기술학회지
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• 제25권4호
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• pp.525-532
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• 2008

To prepare a solution type acrylic pressure-sensitive adhesive, quarter polymers were synthesized from butyl acrylate(BA), 2-ethylhexylacrylate(2-EHA) as a base monomer, methyl methacrylate(MMA) as a comonomer, each of methacrylic acid(MAA), acrylic acid(AA) as a functional monomer. Acrylic solution type pressure-sensitive adhesives(PSA's) of isocyanate derivative crosslinking PSA's were prepared by crosslinking of BEMM, BEMA with toluene-2,4-diisocyanate. The structure of adhesive was identified by FT-IR. The viscosity was measured by using Brookfield DV-III and molecular weight was measured by using gel permeation chromatography. The physical properties of polyethylene film coated with BEMMT, BEMAT were measured as a function of the concentration. As the result, BEMMT(0.6, 0.8), BEMAT(0.6) showed peel adhesion of $160{\sim}180\;g_f$/25 mm width and shear adhesion of more than 24 hours, and tackiness of $4/32{\sim}6/32$ which was relevant to commercial usage.