• Fisheries and Aquatic Sciences
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• v.12 no.2
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• pp.86-89
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• 2009

2,3,6-Tribromo-4,5-dihydroxybenzyl methyl ether (TDB) from the methanolic extract of the red alga Symphyocladia latiuscula exhibits major antioxidant activity. In this study, the activity of TDB against oxidative damage in deoxyribose and DNA was investigated in vitro for potential applications in preventing mutagenesis caused by DNA damage. TDB inhibited the oxidation of deoxyribose at concentrations of up to $1{\mu}g$/mL in the presence of $Fe^{+3}$-EDTA/$H_2O_2$. Furthermore, TDB showed no pro oxidant activity as determined by absence of the reduction of bleomycin-$Fe^{+3}$ to bleomycin-$Fe^{+2}$, which leads to DNA damage. Based on these results, TDB demonstrated considerable antioxidant activity without prooxidant properties.

• Journal of Korean Society of Environmental Engineers
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• v.29 no.6
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• pp.678-683
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• 2007

We isolated a toluene-degrading bacterium, TDB-4, from a bioreactor which designed to remove volatile organic compounds (VOCs) from the contaminated air. Based on the results of 16S rRNA gene analysis, it was classified as Pseudomonas sp. The toluene degradability was estimated in the variable toluene and bacterial concentrations. The bacterial growth and degradation rate was higher in the samples supplied with 50 ${\mu}mole/vial$ of toluene than with 10 ${\mu}mole/vial$. It was decreased, however, in the samples with 100 ${\mu}mole/vial$, indicating that toluene inhibit the growth or degradation activity of TDB-4 at high concentration. When the degradation ability of other compounds was examined, TDB-4 can degrade other VOCs such as styrene, benzene, and xylene. These results will be helpful to optimize the operating conditions to improve the efficiency of a bioreactor in detoxification of VOCs.

• Journal of the Korean Applied Science and Technology
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• v.21 no.3
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• pp.238-245
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• 2004

The interaction between anion and zwitterionic surfactants was investigated by means of surface tension, NMR spectroscopy, and fluorescence studies. These systems are N-tetradecyloxymethyl-N,N-dimethyl betaine ($C_{14}$, TDB), N-octadecyloxymethyl-N,Ndimethyl betaine ($C_{18}$, ODB), and sodium dodecylethoxy sulfate (SDE). These systems show a composition dependency in micellar properties. When the molar fraction of TDB and ODB was about 0.6, the cmc values of these systems showed minima, whereas the solubilized amount of a water insoluble dye, NMR line width showed maxima. These changes comes from the intramolecular complexes formed in the mixed micelles. The complexes are due to the electrostatic interaction of oppositely charged head groups of betaine and sodium dodecylethoxy sulfate. A comparison of betaine and SDE alkyl methylene group line widths to those of n-methyl group indicates that the interior of the micelle in the restricted region is more immobile than the head group.

• Bulletin of the Korean Chemical Society
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• v.23 no.5
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• pp.661-662
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• 2002

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.6B
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• pp.695-701
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• 2006

A toluene-degrading bacterial strain was isolated from a mixed culture that was maintained using toluene as a sole carbon and energy source. The isolated bacterium was classified as Pseudomonas sp. TBD4 based on the close relationship to bacteria belonging to this genus. A bottle study to determine biodegradation rates of individual aromatic compounds showed that the biodegradation was faster in the order of toluene, benzene, styrene, and p-xylene. However, when various mixtures were subjected to TDB4, styrene was degraded at the highest rate, indicating that both toluene and p-xylene could stimulate the degradation of other substrates whereas styrene played as an inhibitor. In addition, the mixed culture and TDB4 were inoculated to the bioactive foam reactor (BFR), and the reactor performance and the corresponding change of microbial community were monitored using the fluorescent in situ hybridization (FISH) method. When an inlet concentration of the VOC mixture increased to greater than 250 ppm, the overall removal efficiency dropped significantly. The FISH measurement demonstrated that the ratio of TDB4 to the total bacteria also decreased to less than 20% along with the decline in removal efficiency in the BFR. As a result, the periodic addition of the pre-grown TDB4 might have been beneficial to achieve a stable performance in the BFR operated over an extended period.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1615-1617
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• 2015

웹을 통한 데이터 공유에 대한 관심의 증가로 RDF 트리플 형태의 데이터가 폭발적으로 증가하고 있다. 대용량 RDF 데이터를 저장하고 빠른 SPARQL 질의 처리를 지원하는 트리플 저장소의 개발이 중요하다. 아파치 프로젝트 중 하나인 Jena-TDB는 가장 잘 알려진 오픈소스 트리플 저장소 중 하나로서 Jena 프레임워크 기반으로 구현됐다. 하지만 Jena-TDB 의 경우 단일 컴퓨터에서 작동하기 때문에 대용량 RDF 데이터를 다룰 수 없다는 문제점이 있다. 본 논문에서는 MongoDB를 활용한 Jena 프레임워크 기반의 트리플 저장소인 Jena-MongoDB를 제안한다. Jena 프레임워크를 사용했기 때문에 기존 Jena-TDB와 동일한 인터페이스로 사용할 수 있고 최신 표준 SPARQL 문법도 지원한다. 또한 MongoDB를 사용했기 때문에 분산환경에서도 작동할 수 있다. 대용량 LUBM 데이터셋에 대한 SPARQL 질의 처리 실험결과 Jena-MongoDB가 Jena-TDB 보다 빠른 질의 응답 속도를 보여줬다.

• Proceedings of the Korean Information Science Society Conference
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• 2002.04b
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• pp.136-139
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• 2002

연관규칙 마이닝과정에서의 빈발항목 탐색의 대표적인 방법으로 알려진 Apriori 알고리즘의 성능을 향상시키기 위한 많은 연구가 진행되어 왔다. 본 논문에서는 트랜잭션 데이터베이스(TDB)에서 생성되는 각 패스의 k-itemset들에 대해 각각 트랜잭션 ID List(TIDist)를 유지하고 이를 이용해 (k+1)-itemset을 효율적으로 찾아내는 방법을 제안한다. 이 방법은 frequent (k+1)-itemset(k>0)의 빈도수 및 TIDList를 TDB 에 대한 스캔이 전혀 없이 k-itemset의 TIDList로부터 직접 구한다. 이는 빈발항목집합을 찾기 위한 탐색 complexity는 크게 줄여줄 뿐 아니라 시간 변화에 따른 빈발항목집합의 분포 정보를 제공해 준다.

• Journal of Korean Society of Water and Wastewater
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• v.24 no.3
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• pp.287-293
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• 2010

In this study, the toluene gas in VOCs was removed using bioreactor which applied with hollow fiber membrane and Pseudomonas sp. TDB-4. The EBRT of each reactor are controlled 60 sec(R-1) and 30 sec(R-2) and inlet tolune concentration of both R-1 and R-2 is controlled from 25ppm to 500 ppm. Up to 500 ppm of toluene concentration, the toluene removal efficiency of R-1 and R-2 are 92% and 81%, and theirs removal capacities are about 100 g/$m^3$/hr and 180 g/$m^3$/hr, respectively. In addition, according to this study, toluene removal efficiencies at the hollow fiber are approximately 70%(60 sec) and 45%(30sec).

• Annual Conference on Human and Language Technology
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• 2014.10a
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• pp.153-155
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• 2014

사용자가 질의한 내용에 대한 결과를 찾기 위해 본 논문은 DBPedia에서 제공해주는 트리플 구조를 TDB에 저장하고, 사용자 질의 문장에서 트리플을 찾은 뒤 해당 문장의 규칙을 추론하여 SPARQL 쿼리를 생성한 뒤, 마지막으로 Fuseki를 이용해 결과를 출력하는 Q&A시스템을 제안한다. SPARQL 쿼리를 생성함에 있어 질의의 정답을 찾아내는 타겟이 있다는 점과 한국어의 조사와 부사부분에서 쿼리가 변형될 수 있다는 점을 통해 유동적인 쿼리를 생성한다. 그리고 DBPedia에 없는 단어가 질의에서 나타날 수 있기 때문에 이를 정제해주는 작업 또한 필요하다. 한국어는 어절순서가 고정적이지 않다는 점, 조사, 부사에 의해 문장의 의미가 변형되는 또 다른 부분을 파악하여 앞으로 시스템을 개발함에 있어 정확률을 상승시킬 예정이다.

• YAKHAK HOEJI
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• v.37 no.5
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• pp.544-548
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• 1993

The pharmacokinetics of DWP302, a new combined ranitidine preparation in rats and dogs was studied using HPLC. DWP302 was composed of ranitidine, sucralfate and tripotassium dicitrato bismuthate. Especially, this study was focused on the possibilities that the concomitant administration of either sucralfate or TDB may affect the absorption of orally administered ranitidine. Ranitidine and DWP302 were orally administered to rats at a dose of ranitidine 10mg/kg. Several rats showed the biphasic peak of plasma concentration. AUC$_{S_{0-8}}$ of ranitidine and DWP302 group were found to be 1040$\pm$109 and 945$\pm$124 ng.hr/ml, respectively, and there was no significant difference between both AUCs. In a cross-over study for dogs, $C_{max}$, t$_{1/2}$ beta and total AUC of ranitidine group were found to be 625.8$\pm$86.7 ng/ml, 2.80$\pm$0.28 hr and 1688$\pm$127 ng.hr/ml, and those of DWP302 group were 562.6$\pm$120.9 ng/ml, 3.05$\pm$0.30 hr and 1673$\pm$123 ng.hr/ml, respectively. There was no significant difference between those parameters, but Tmax of DWP302 group (1.69$\pm$0.31 hr) was significantly different from ranitidine group (1.13$\pm$0.26 hr). The results suggest that either sucralfate or TDB may affect the lag-time or rate of absorption of ranitidine but not the extent of absorption.