• Title/Summary/Keyword: TCi

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Safety and efficacy of target controlled infusion administration of propofol and remifentanil for moderate sedation in non-hospital dental practice

  • Douglas Lobb;Masoud MiriMoghaddam;Don Macalister;David Chrisp;Graham Shaw;Hollis Lai
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.23 no.1
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    • pp.19-28
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    • 2023
  • Background: Fearful and anxious patients who find dental treatment intolerable without sedative and analgesic support may benefit from moderate sedation. Target controlled infusion (TCI) pumps are superior to bolus injection in maintaining low plasma and effect-site concentration variability, resulting in stable, steady-state drug concentrations. We evaluated the safety and efficacy of moderate sedation with remifentanil and propofol using TCI pumps in non-hospital dental settings. Methods: A prospective chart review was conducted on 101 patients sedated with propofol and remifentanil using TCI pumps. The charts were completed at two oral surgeons and one general dentist's office over 6 months. Hypoxia, hypotension, bradycardia, and over-sedation were considered adverse events and were collected using Tracking and Reporting Outcomes of Procedural Sedation (TROOPS). Furthermore, patient recovery time, sedation length, drug dose, and patient satisfaction questionnaires were used to measure sedation effectiveness. Results: Of the 101 reviewed sedation charts, 54 were of men, and 47 were of women. The mean age of the patients was 40.5 ±18.7 years, and their mean BMI was 25.6 ± 4.4. The patients did not experience hypoxia, bradycardia, and hypotension during the 4694 min of sedation. The average minimum Mean Arterial Pressure (MAP) and heartbeats were 75.1 mmHg and 60.4 bpm, respectively. 98% of patients agreed that the sedation technique met their needs in reducing their anxiety, and 99% agreed that they were satisfied with the sedation 24 hours later. The average sedation time was 46.9 ± 55.6 min, and the average recovery time was 12.4 ± 4.4 min. Remifentanil and propofol had mean initial effect-site concentration doses of 0.96 µ/.ml and 1.0 ng/ml respectively. The overall total amount of drug administered was significantly higher in longer sedation procedures compared to shorter ones, while the infusion rate decreased as the procedural stimulus decreased. Conclusion: According to the results of this study, no patients experienced adverse events during sedation, and all patients were kept at a moderate sedation level for a wide range of sedation times and differing procedures. The results showed that TCI pumps are safe and effective for administering propofol and remifentanil for moderate sedation in dentistry.

국제전기기술회의에 참가하고서

  • 이승원
    • JOURNAL OF ELECTRICAL WORLD
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    • no.9 s.33
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    • pp.25-29
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    • 1979
  • 필자는 호주 시드니대학에서 79년 5월 21일부터 6월 2일까지 12일간에 걸쳐 개최된 제 44차 I.E.C총회에 대한전기협회회원의 자격으로 참석하였다. 또 I.E.C한국위원회위원을 맡고 있는 관계로서 이사회에도 참석할 수 있었으며, EH 공진청의 지정에 의하여 용어전문위원회(TCI)와 전압전문위원회(TC8)에도 참석한 바 있었으므로 이에 관하여 간략히 전번호에 이어 소개한다

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국제전기기술회의에 참가하고서

  • 이승원
    • JOURNAL OF ELECTRICAL WORLD
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    • no.8 s.32
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    • pp.31-35
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    • 1979
  • 필자는 호주 시드니대학에서 79년 5월 21일부터 6월 2일까지 12일간에 걸쳐 개최된 제 44차 I.E.C총회에 대한전기협회회원의 자격으로 참석하였다. 또 I.E.C한국위원회위원을 맡고 있는 관계로서 이사회에도 참석할 수 있었으며, EH 공진청의 지정에 의하여 용어전문위원회(TCI)와 전압전문위원회(TC8)에도 참석한 바 있었으므로 이에 관하여 간략히 소개하기로 한다.

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Utilization of Saline Solutions in the Modification of Lignocellulose from Champaca Wood

  • Sangian, Hanny F.;Sehe, Muhammad Rifai;Tamuntuan, Gerald H.;Zulnazri, Zulnazri
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.4
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    • pp.368-379
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    • 2018
  • Objective of this work is to study the effects of a saline solution used to pretreat lignocellulosic material derived from champak timber. The native lignocellulosic solids, in powder form, were mixed with saline water solutions of three different concentrations and maintained for 2 weeks without stirring. The treated solids were washed, recovered, and then dried under sunlight. The substrates were characterized using X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, and scanning electron microscopy (SEM). The crystallinity (CrI), lateral order index (LOI), total crystallinity index (TCI), and surface morphologies of all the samples were determined. The treated biomass structures were compared with controls. The data show that the structures of all the treated substrates changed, as indicated by CrI. CrI of the treated substrates decreased significantly compared with that of the original wood, as did LOI and TCI quantities, whereas the HBI parameter increased. The results indicate that the saline water pretreatment modified the wood samples.

Clinical Meaning of Hallucinatory Experience among PTSD Patients (외상 후 스트레스 장애 환자에서 발생한 환각 경험의 임상적 의미)

  • Park, Ji Hoon;Yi, Jung Seo;Lee, Hong Seock
    • Anxiety and mood
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    • v.9 no.2
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    • pp.113-120
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    • 2013
  • Objectives : The aim of this study was to investigate clinical meaning of hallucination among patients with posttraumatic stress disorder (PTSD). Methods : PTSD patients with hallucination (n=50) were selected and matched with the PTSD patients without hallucination (n=50) by age and sex. The patients were evaluated in two different aspects, pathologic aspects which can develop after traumatic event, and positive/adaptive aspects which are concerned in positive psychology. In addition to these, temperament and character features between two groups were also evaluated using the Temperament and Character Inventory (TCI). Results : Except for the total score of DES (Dissociative Experience Scale) and the score of re-experience subscale of CAPS (Clinician Administered PTSD Scale), clinical characteristics did not show any significant difference between the two groups. Among the comparison of seven higher dimensions in TCI profiles, only Self-transcendence showed significant difference between the two groups. Conclusion : The two groups did not show significant differences in pathologic aspects except for factors that may contribute to development of hallucination. Furthermore, authors could not find any differences in positive/adaptive aspects.

Relationships between Chronotypes and Temperament and Character Dimensions in Healthy Young Adults (젊은 성인에서 일주기유형과 기질 및 성격의 관련성)

  • Park, Chun Il;Kang, Jee In;Namkoong, Kee;Kim, Se Joo
    • Korean Journal of Biological Psychiatry
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    • v.21 no.3
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    • pp.93-98
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    • 2014
  • Objectives Circadian rhythms have been known to have associations with psychiatric disorders and personality traits. The present study investigated the relationships between circadian typology and temperaments/characters in a non-clinical Korean population. Methods Two hundred six healthy Korean college students (male 109, female 97) participated in this study. The subjects completed the Composite Scale of Morningness for circadian typology and 140-item Temperament and Character Inventory-Revised-Short version (TCI-RS). Results Multivariate analyses of covariance showed a significant association between chronotypes and temperamental dimensions of the TCI-RS. Morning types were significantly associated with lower harm avoidance and higher persistence and self-directedness dimensions, compared to evening types and intermediate types. No interaction effects between sex and chronotypes were shown for temperamental dimensions. Conclusions The present findings suggest that high persistence and self-directedness characters are related to morning types and high harm avoidance temperament is more related to evening types.

Effect-site Concentration of Alfentanil or Remifentanil for the Relief of Postoperative Pain in the Intensive Care Unit Patients

  • Jang, Hae-Lan;Kang, Hoon
    • International Journal of Contents
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    • v.11 no.2
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    • pp.69-73
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    • 2015
  • This study was performed to determine the optimal doses of alfentanil or remifentanil (effect-site concentrations) required to prevent pain and other suffering after abdominal general surgery in ICU patients. A total of 52 general abdominal surgical patients (ASA IIIII) requiring artificial ventilatory care in the ICU were provided with either alfentanil (24 patients) or remifentanil (28 patients) through target controlled infusion (TCI). Alfentanil and remifentanil concentrations were titrated up and down until the pain score became less than 3 (VAS; Visual Analogue Score < 3). The effect-site concentrations (ng/ml) of alfentanil or remifentanil required to adequately control postoperative pain in the ICU were 64 +/- 12 and 1.9 +/- 0.5 for intubation with artificial ventilation, 57 +/- 9 and 1.7 +/- 0.7 for intubation with spontaneous ventilation, and 41 +/- 10 and 1.2 +/- 0.5 after extubation, respectively. Pain scores and the corresponding opioid concentrations were independent from respiratory condition. The three effect-site concentrations of alfentanil and remifentanil obtained from this clinical trial using the TCI technique can be a guideline in the administration of the same opioids to relieve the discomfort of ICU patients who have undergone abdominal general surgery.

Evaluating Production Efficiency in a Fisheries Wholesale Sector (수산물 도매업의 생산 효율성 평가에 관한 연구)

  • Pyo, Hee-Dang;Kim, Jong-Chean
    • The Journal of Fisheries Business Administration
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    • v.41 no.3
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    • pp.21-44
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    • 2010
  • The paper estimates changes in total factor productivity and technical efficiency change index and technical change index using Malmquist productivity index(MPI) in fisheries wholesale products over the time period of 2006 through 2008. The model considers a number of employees and operating costs as input factors, and sales and EBIT(earnings before tax and interest) as output factors. The results indicate that, between 2006 and 2007, there is in general technical progress in which TCI(Technical Change Index) indicates 2.7994 in the sale scale of 50 million won through 100 million won, while there are no efficiency in TECI(Technical Efficiency Change Index), PECI(Pure Efficiency Change Index) and SECI(Scale Efficiency Change Index) which are estimated to be around 1. Between 2007 and 2008 technical efficiency and technical progress are generally declined, compared to those of 2006 and 2007. Wilcoxon's rank-sum test shows that there are statistically significant difference of TCI and MPI between two periods at the level of 5%, while there are statistically significant difference of TECI, PECI and SECI between two periods at the level of 5%.

Effects of Intake Swirl and Combustion Parameters on the Performance and Emission in a V8 Type Turbocharged Intercooler Diesel Engine (흡기 선회유동 및 연소인자가 V8형 TCI 디젤엔진의 성능 및 배출가스특성에 미치는 영향)

  • Yoon Junkyu;Cha Kyungok
    • Transactions of the Korean Society of Automotive Engineers
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    • v.13 no.4
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    • pp.135-144
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    • 2005
  • The Effects of intake swirl and combustion parameters on the performance and emission characteristics in a V8 type turbocharged intercooler D.I. diesel engine of the displacement $16.7\iota$ were studied experimentally in this paper. Generally the swirl in the combustion process of diesel engine promotes mixing of the injection fuel and the intake air. Also, TCI diesel engine is put to practically use intercooler in order to increase boost efficiency which is cooled boost air. As a result of steady flow test, when the swirl ratio is increased, the mean flow coefficient is decreased, whereas the Gulf factor is increased. And through engine test, its can be effected to meet performance and emission by optimizing the main parameters; the swirl ratio is 2.25, compression ratio is 17.5, combustion bowl is re-entrant $8.5^{\circ}$, nozzle hole diameter is $\phi0.33^{\ast}3+\phi0.35^{\ast}2$, injection timing is BTDC $12^{\circ}CA$ and turbocharger is T02 model which are compressor 0.6A/R+46trim and turbine 1.0A/R+57trim.