• The Korean Journal of Cytopathology
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• v.7 no.2
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• pp.134-137
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• 1996

Monoclonal antibody(TCM-9) against human thyroid cancers have been studied by screening with human thyroid cancers, normal and benign thyroid tissue, and normal human serum protein. A monoclonal antibody(TCM-9) that is known to have strong specificity for human thyroid cancer but not for Graves' disease, adenoma or normal thyroid does not bind to native or mature human thyroglobulin(Tg). We used to TCM-9 antibody by immunohistochemical staining on 5 follicular cancer, 2 follicular adenoma, 1 follicular neoplasm with suspicious invasion, 2 papillary cancer to ascertain being of help in differentiation between follicular carcinoma and adenoma. Reactivity of TCM-9 was observed in follicular carcinoma and papillary carcinoma but not observed in follicular adenoma. Thus TCM-9 is a novel monoclonal antibody against the thyroid cancer.

• Journal of Environmental Impact Assessment
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• v.7 no.1
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• pp.63-70
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• 1998

TCM has been used for many environmental impact assessments in Korea. But there was reported that an error was found in area source calculation of original TCM and modified. In this study, TUM(TCM-urban mode) and TRM(TCM-rural mode) were developed for urban and rural area by modification of original TCM. McElroy-Pooler dispersion parameter was used for area and point source in TUM, Pasquill-Gifford parameter was used for area and point source in TRM. And Irwin's vertical wind speed profile exponents were used for TUM and TRM. Then predicted value by TUM, TRM and a value from the same area and point data by CDM2, ISCLT3 were compared. And it was found that predicted value from point source by TUM, TRM was very similar to a value by CDM2, ISCLT3, and predicted value from area source by TRM was similar to a value by CDM2, ISCLT3. But predicted value from area: source by TUM was an half lower than a value by CDM2, ISCLT3.

• Advances in Traditional Medicine
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• v.5 no.2
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• pp.156-159
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• 2005

The protective effect of Naoxingtong (NXT) on rat cerebral microvascular endothelial cell (rCMEC) was investigated. rCMEC was injured in vitro by incubating for 4 hours at 100% NO in a hypoxia chamber. After treated with NXT-containing serum, the cellular viability rate (90.3%) was significantly elevated when compared with that of control group and the inhibitive rate of lactic dehydrogenase activity (9.2%) was far lower than the control group with dose-dependent effect. The results indicate that NXT can increase viability of rCMEC, and protect cell membrane from injury during hypoxia.

• Journal of the Korea Society of Computer and Information
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• v.4 no.4
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• pp.185-192
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• 1999

In this paper. for $\pi$/4 and $\pi$/8 PSK. we proposed to condition to obtain coding gain increasing states, by design encoder of analytical method with minimal complexity in limited bandwidth and power channels. In order to improve the bit error rate(BER), comparing Ungerboeck designed the TCM. we propose MTCM(Multiple trellis-coded modulation) with multiplicity(k＝2), by optimum encoder design. By design encoder of analytical method. the trellis encoder can be minimal complexity and the decoder be used Viterbi decoder(MLSE). When compared to the TCM and MTCM with AWGN channels. the condition of performance enhancement of the MTCM with multiplicity(k＝2) is the case of parallel transition in TCM systems. without alternating data transmission rate in bandwidth and power limited channels.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.12
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• pp.141-148
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• 2005

This paper addresses the design of srTCM (single rate Three Color Marker) described in RFC2697. It has proposed for srTCM to be used at the ingress of Differentiated Service network that provides AF PHB (Assured Forwarding Per Hop Behavior). srTCM is the marker with the metering function, and consists of the token updating function and the marking function. The token updating function uses the dual token bucket. The marking function compares the token values with the length of input packet, and then marks the result into IP QoS field (ToS field). This paper designs srTCM function and then implements it in one chip using VHDL and FPGA technology.

• The Journal of Korean Institute of Information Technology
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• v.17 no.3
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• pp.31-41
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• 2019

In this paper, we design and implement the simulator for the transmitter and receiver of 4D-8PSK TCM with 2.0, 2.25, 2.5, and 2.75 bits/symbol-channel transmission efficiency recommended by the CCSDS for satellite communications, and then analyze the BER performance of 4D-8PSK TCM system in AWGN channel. The transmitter of 4D-8PSK TCM is designed in accordance with the recommendation in the CCSDS standard. Meanwhile, for the receiver design of 4D-8PSK TCM, we design the differential decoder generalizing the differential encoder/decoder scheme. The trellis decoding algorithm is designed by applying the auxiliary trellis information and the Viterbi algorithm, and an 8-dimensional constellation mapper equation given in the CCSDS standard is deconstructed to design constellation mapper. Especially, we present the optimized receiver for 4D-8PSK TCM system by investigating the BER performances for the traceback lengths in the Viterbi decoder through computer simulations..

• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.

• Journal of Korean Medical classics
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• v.23 no.5
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• pp.117-122
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• 2010

The relationship between river-table and five-type individuals with yin-yang's greater and lesser properties from NeiJingaswellasKoreansasangmedicinewasexplored.1.Rivertableisthetheoreticalbasisforthefive-typeconstitutionswithyin-yang'sgreaterandlesserpropertiesandKoreansasangconstitutions:Thecontentoffour-manifestationconstitutionswithyin-yang'greaterandlesserpropertiesinLingShuTongTian,isrelatedtoChangeBook,andcouldbeexplainedandgeneralizedwithriver-table;itissaidthatKoreansasangconstitutionfoundedbyYiJeMaalsostemmedformLingShuTongTian,butitstheoreticalsystemisdifferentfromthatofLingShuTongTian.Thoughthissystemcanbeexplainedandgeneralizedwithriver-table,itsdistributionofinternalorgansisdifferentfromthatofLingShuTongTian.2.Theclinicalmanifestationsoffour-manifestationconstitutionwithyin-yang'slesserandgreaterprpertiesofTCM,includingpersonality,behaviorpatternandliabilitytocertaindiseases,wereexploredandtheregulatingandcultivatingprinciplesbasedonriver-tabletofour-manifestationconstitutionswithyin-yang'sgreaterandlesserpropertiesalsowereestablished:IndividualsofShaoyang(lesseryang)constitutionshouldpayattentiontoliverqi'sascendinganddispersing,andharmonizationofliveryinandliveryanginspring;individualsofTaiyang(greateryang)constitutionshouldemphasizetheclearinganddescendingofheartqiandharmonizationofheartyinandheartyanginsummer;individualsofShaoyin(lesseryin)constitutionshouldattachimportancetodispersing,purifyinganddescendingoflungqiandharmonizationoflungyinandlungyanginautumn;individualsofTaiyin(greateryin)shouldlaystressonthecultivatingofkidneyqi'sascendingandsteaming,andharmonizationofkidneyyinandkidneyyanginwinter.Besides,individualsofthefourtypesmentionedaboveshouldcultivateandregulateqiofspleenandstomach,fortheascending-descendingandharmonizationofstomachqiandspleenqiisthebasisforthenormalorhealthybodyconstitution,andtheroottoremedythetendenciesoffour-manifestationconstitutions.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.1C
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• pp.84-89
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• 2002

In this paper the Viterbi decoder which is used for TCM decoding in wireless modem system under transmission of audio data for the high quality sound is designed by VHDL and implemented by FPGA. After making short explanation about TCM encoding and decoding. I show the effect of channel in computer by using encoder and decoder implemented in FOGA and the bit error rate according to change rate of ($E_b/N_0$).

• Journal of the Korean Society of Radiology
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• v.9 no.5
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• pp.279-285
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• 2015

The eye of human is a radiation sensitive organ and this organ should be shielded from radiation exposure during brain CT procedures. In the brain CT procedures, bismuth protector using to reduce the radiation exposure dose for eye. But protecting the bismuth always accompanies problem of the image quality reduction including artifact. This study aim is the eye radiation exposure dose and image quality evaluation of the new tube current modulation such as new organ based-tube current modulation, longitudinal-TCM, angular-TCM between shielding scan technique using bismuth and lead glasses. As a result, radiation dose of eye is reduced 25.88% in new OB TCM technique then reference scan technique and SNR new OB TCM is 6.05 higher than bismuth shielding scan technique and lower than reference scan technique. In clinical brain CT, new OB TCM technique will contribute to reduction of radiation dose for eye without decrease of image quality.