• 대한세포병리학회지
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• 제7권2호
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• pp.134-137
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• 1996

Monoclonal antibody(TCM-9) against human thyroid cancers have been studied by screening with human thyroid cancers, normal and benign thyroid tissue, and normal human serum protein. A monoclonal antibody(TCM-9) that is known to have strong specificity for human thyroid cancer but not for Graves' disease, adenoma or normal thyroid does not bind to native or mature human thyroglobulin(Tg). We used to TCM-9 antibody by immunohistochemical staining on 5 follicular cancer, 2 follicular adenoma, 1 follicular neoplasm with suspicious invasion, 2 papillary cancer to ascertain being of help in differentiation between follicular carcinoma and adenoma. Reactivity of TCM-9 was observed in follicular carcinoma and papillary carcinoma but not observed in follicular adenoma. Thus TCM-9 is a novel monoclonal antibody against the thyroid cancer.

• 환경영향평가
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• 제7권1호
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• pp.63-70
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• 1998

TCM has been used for many environmental impact assessments in Korea. But there was reported that an error was found in area source calculation of original TCM and modified. In this study, TUM(TCM-urban mode) and TRM(TCM-rural mode) were developed for urban and rural area by modification of original TCM. McElroy-Pooler dispersion parameter was used for area and point source in TUM, Pasquill-Gifford parameter was used for area and point source in TRM. And Irwin's vertical wind speed profile exponents were used for TUM and TRM. Then predicted value by TUM, TRM and a value from the same area and point data by CDM2, ISCLT3 were compared. And it was found that predicted value from point source by TUM, TRM was very similar to a value by CDM2, ISCLT3, and predicted value from area source by TRM was similar to a value by CDM2, ISCLT3. But predicted value from area: source by TUM was an half lower than a value by CDM2, ISCLT3.

• Advances in Traditional Medicine
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• 제5권2호
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• pp.156-159
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• 2005

The protective effect of Naoxingtong (NXT) on rat cerebral microvascular endothelial cell (rCMEC) was investigated. rCMEC was injured in vitro by incubating for 4 hours at 100% NO in a hypoxia chamber. After treated with NXT-containing serum, the cellular viability rate (90.3%) was significantly elevated when compared with that of control group and the inhibitive rate of lactic dehydrogenase activity (9.2%) was far lower than the control group with dose-dependent effect. The results indicate that NXT can increase viability of rCMEC, and protect cell membrane from injury during hypoxia.

• 한국컴퓨터정보학회논문지
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• 제4권4호
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• pp.185-192
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• 1999

본 논문에서는 Ungerboeck가 설계한 TCM과 Divsalar가 제안한 다중화 지수(k＝2)의 다중 트렐리스 변조 (Multiple trellis-coded modulation)을 최적의 부호기 설계를 통하여 상태수의 증가에 따라 대역폭과 전력이 제한된 환경에서 부호화 이득을 얻을 수 있는 조건들을 제안하였다. 해석적 기법의 부호기 설계를 통하여 최적의 트렐리스 부호기를 간단히 구성하였으며, 복호는 비터비 최우복호(MLSE)를 적용하였다. QPSK와 8PSK에서 TCM 시스템에서 상태수가 2상태, 4상태, 8상태로 증가함에 따라 다중화 지수(k=2)의 MTCM과 TCM의 성능을 비교하였으며, 상태수가 매우 작아서 TCM의 트렐리스 선도에 병렬천이가 있을 경우 가우시안 채널에서 MTCM 시스템은 대역폭의 확장없이 TCM 시스템보다 우수한 부호화 이득을 얻을 수 있다.

• 대한전자공학회논문지TC
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• 제42권12호
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• pp.141-148
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• 2005

본 논문은 RFC2697에서 제안된 srTCM (single rate Three Color Marker)의 설계에 관한 것이다. srTCM은 AFPHB(Assured Forwarding Per Hop Behavior)를 제공하는 DS (Differentiated Service) 네트워크의 Ingress에서 사용되도록 제안되었다. srTCM은 metering 기능을 가진 marker이며, 토큰 갱신기능과 marking 기능으로 구성된다. 토큰 갱신 기능은 듀얼 토큰버킷을 사용하며, marking 기능은 토큰 값을 입력 패킷의 길이와 비교하여, 그 결과를 IP QoS 필드 (ToS 필드)에 마킹한다. 본 논문에서는 이와 같은 srTCM를 VHDL과 FPGA를 이용하여 설계하여 하나의 chip으로 구현하였다.

• 한국정보기술학회논문지
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• 제17권3호
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• pp.31-41
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• 2019

본 논문에서는 CCSDS에서 권고하고 있는 대역폭 효율적인 변조 방식 중 채널당 2.0, 2.25, 2.5, 2.75 bits/symbol의 전송효율을 가지는 4D-8PSK TCM 시스템의 송신부와 수신부를 설계하고 시뮬레이터를 구현하여 AWGN 환경에서 모의시험을 통하여 BER 성능을 분석한다. 송신부는 CCSDS 표준을 준용하여 설계하고, 수신부는 차동 부호화 및 복호화를 일반화하여 차동 복호기를 설계하며, 트렐리스 복호 알고리즘은 보조격자의 정보와 비터비 알고리즘을 적용하여 설계하고, CCSDS 표준에서 주어진 8차원 성상도 맵퍼의 방정식을 가감법으로 풀어 성상도 디맵퍼를 설계한다. 특히, 컴퓨터 모의실험을 통해 비터비 복호기 설계 시 역추적 깊이에 따른 오류 성능을 제시하여 4D-8PSK TCM 시스템의 최적화된 송/수신부를 구현하고 성능을 분석한다.

• 대한예방한의학회지
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• 제21권2호
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.

• 대한한의학원전학회지
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• 제23권5호
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• pp.117-122
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• 2010

The relationship between river-table and five-type individuals with yin-yang's greater and lesser properties from NeiJingaswellasKoreansasangmedicinewasexplored.1.Rivertableisthetheoreticalbasisforthefive-typeconstitutionswithyin-yang'sgreaterandlesserpropertiesandKoreansasangconstitutions:Thecontentoffour-manifestationconstitutionswithyin-yang'greaterandlesserpropertiesinLingShuTongTian,isrelatedtoChangeBook,andcouldbeexplainedandgeneralizedwithriver-table;itissaidthatKoreansasangconstitutionfoundedbyYiJeMaalsostemmedformLingShuTongTian,butitstheoreticalsystemisdifferentfromthatofLingShuTongTian.Thoughthissystemcanbeexplainedandgeneralizedwithriver-table,itsdistributionofinternalorgansisdifferentfromthatofLingShuTongTian.2.Theclinicalmanifestationsoffour-manifestationconstitutionwithyin-yang'slesserandgreaterprpertiesofTCM,includingpersonality,behaviorpatternandliabilitytocertaindiseases,wereexploredandtheregulatingandcultivatingprinciplesbasedonriver-tabletofour-manifestationconstitutionswithyin-yang'sgreaterandlesserpropertiesalsowereestablished:IndividualsofShaoyang(lesseryang)constitutionshouldpayattentiontoliverqi'sascendinganddispersing,andharmonizationofliveryinandliveryanginspring;individualsofTaiyang(greateryang)constitutionshouldemphasizetheclearinganddescendingofheartqiandharmonizationofheartyinandheartyanginsummer;individualsofShaoyin(lesseryin)constitutionshouldattachimportancetodispersing,purifyinganddescendingoflungqiandharmonizationoflungyinandlungyanginautumn;individualsofTaiyin(greateryin)shouldlaystressonthecultivatingofkidneyqi'sascendingandsteaming,andharmonizationofkidneyyinandkidneyyanginwinter.Besides,individualsofthefourtypesmentionedaboveshouldcultivateandregulateqiofspleenandstomach,fortheascending-descendingandharmonizationofstomachqiandspleenqiisthebasisforthenormalorhealthybodyconstitution,andtheroottoremedythetendenciesoffour-manifestationconstitutions.

• 한국통신학회논문지
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• 제27권1C호
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• pp.84-89
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• 2002

제출된 논문에서는 고음질의 오디오 신호를 전송하는 무선 모뎀의 수신부에서 TCM 복호와에 사용되는 Viterbi 디코더를 VHDL을 이용하여 설계하고 FPGA를 이용하여 구현하였다. 이 논문에서는 TCM 부호화와 복호화와 복호화 과정을 간단히 설명한 후 부호화기와 복호화기를 FPGA로 구현한 다음 PC 상에서 채널의 영향을 재현하여 신호 대잡음비($E_b/N_0$) 변화에 따른 시스템의 비트에러율 성능을 제시하고 있다.

• 한국방사선학회논문지
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• 제9권5호
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• pp.279-285
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• 2015

두부 CT 검사에서 눈의 수정체는 높은 방사선 감수성으로 보호되어야 할 장기 중에 하나이다. 두부 CT 검사에서 눈의 피폭선량감소 목적으로 사용되는 비스무스 차폐체는 현저한 선량 감소 효과가 있지만 화질저하의 문제점이 있다. 본 연구는 인체팬텀을 이용한 두부 CT 검사에서 피폭 선량을 줄이기 위해 사용되는 관전류변조기법인 new organ based-tube current modulation, longitudinal-TCM, angular-TCM과 차폐기법인 비스무스, 납 안경을 사용하여 눈의 선량과 화질의 변화 정도를 평가하였다. 연구결과, new OB-TCM에서 눈의 선량은 25.88% 감소되었으며 비스무스를 사용한 검사와 비교하여 CT number, 노이즈, SNR의 변화가 작은 것을 확인하였다. 따라서 new OB-TCM을 임상의 두부 CT 검사에 적용할 경우, 눈의 피폭선량을 감소시키면서 영상의 화질 저하를 방지할 수 있을 것으로 기대된다.