• Title/Summary/Keyword: TC/HDL-C

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Biochemical Analysis of Crew's Blood and Urine before & after Long-Term Navigation (원양항해 전과 후 선원의 혈액 및 소변의 생화학적 분석)

  • Ha Hae-Dong;Moon Serng-Bae;Jun Seung-Hwan;Jeong Eun-Seok;Kim Jae-Ho
    • Journal of Navigation and Port Research
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    • v.30 no.5 s.111
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    • pp.415-420
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    • 2006
  • Urinalyses have been conducted for 28 crew's in H University's training ship and creatine and uric acid turned out to be higher in all ages, which can be inferred that board job has caused negative impact on kidney and/or malfunction In addition, TC and HDL-C, LDL-C ha; decreased, however, TG has increased after the navigation. All different positions including officer, crew, decker, engineer and radio part showed the similar pattern TC and HDL-C has decreased in 30s, 40s and TG has increased in 30s. A few of the 30's show extremely high TG rates so hyperlipidemia is suspected. 7 members turned out positive for UBG test and 5 positive for PRO test. Especially there was only one UBG positive before the navigation but, 7 members has become positive, which means the one-month long-tenn navigation has definite impact on the liver cell function.

Biochemical Analysis of the seamen's blood and urine before & after the ocean navigation (원양항해 전과 후 선원의 혈액 및 소변의 생화학적 분석)

  • Ha Hae-Dong;Moon Serng-Bae;Jun Seung-Hwan;Jeong Eun-Seok;Kim Jae-Ho
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2006.06b
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    • pp.5-11
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    • 2006
  • Urinalyses have been conducted for 28 seamen in K University's training ship and Creatine and Uric acid turned out to be higher in all ages, which can be inferred that on-deck environment has caused negative impact on kidney and/or malfunction. In addition, TC arid HDL-C, LDL-C has decreased, however, TG has increased after the navigation. All different positions including oater, crew, decker, engineer and radio part showed the similar pattern. TC and HDL-C has decreased in 30s, 40s and TG has increased in 30s. A few of the 30's show extremely high TG rates so Hyperlipidemia is suspected. 7 members fumed out positive for UBG test and 5 positive for PRO test. Especially there was only one UBG positive before the navigation but, 7 members has become positive, which means the one-month ocean navigation has definite impact on the liver cell function.

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Mulberry (Morus alba L.) ethanol extract attenuates lipid metabolic disturbance and adipokine imbalance in high-fat fed rats

  • Da-jung, Noh;Gun-Ae, Yoon
    • Nutrition Research and Practice
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    • v.16 no.6
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    • pp.716-728
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    • 2022
  • BACKGROUND/OBJECTIVES: An imbalanced adipokine profile in obesity increases the susceptibility to obesity-related cardiometabolic alterations, including type 2 diabetes, hypertension, dyslipidemia, and non-alcoholic fatty liver disease. The mulberry plant has been reported to have health benefits, such as hypolipidemic and hepatoprotective effects. This study examined the effects of a mulberry (Morus alba L.) fruit ethanol extract (MBEE) on dyslipidemia, liver steatosis, and adipokine imbalance in response to a high-fat diet. MATERIALS/METHODS: Male Sprague-Dawley rats were assigned to one of 4 groups containing 6 rats each and fed either a control diet (CON), a high-fat diet (HFD), or a high-fat diet with MBEE of 150 mg/kg/day (LMB) or 300 mg/kg/day (HMB). The triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were measured spectrophotometrically. The leptin, adiponectin, and plasminogen activator inhibitor-1 (PAI-1) levels were determined by an enzyme-linked immunosorbent assay. RESULTS: The plasma TG levels were similar in the 4 groups. Plasma cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and TC/HDL-C ratio increased in the HFD group compared with the CON group, whereas those values decreased in the LMB group (P < 0.05), indicating that MBEE had a plasma lipid-lowering effect. HDL-C decreased in the HFD group, but MBEE did not affect the HDL-C level. The HFD rats significantly increased hepatic TG and cholesterol levels and plasma ALT and AST activities compared to the CON group. The hepatic TG level and ALT and AST activities were reduced markedly by the MBEE treatment. The HFD group showed a higher PAI-1 level, whereas MBEE treatment, especially in the HMB group, significantly reduced leptin level, and leptin/adiponectin and PAI-1/ adiponectin ratios. These findings suggest that MBEE altered the imbalance between the pro-and anti-inflammatory adipokines to a more anti-inflammatory state. CONCLUSIONS: MBEE could protect against abnormal lipid metabolism and hepatic steatosis induced by a high-fat diet, lowering plasma cholesterol, LDL-C and TC/HDL-C, and hepatic TG. These findings are associated with the regulating effect of MBEE on the leptin/adiponectin and PAI-1/adiponectin ratios.

Effects of Regular Walking Exercise on Health-Related Parameters in Persons with Chronic Diseases (규칙적인 걷기운동이 질환별 노인의 건강변인에 미치는 효과)

  • Lim, Hwe-Jin;Kim, Yu-Sik;Cho, Hyeong-Suk;Kim, Chang-Hee;Lim, Hee-Jung;Jeong, Hee-Seong;Im, Jee-Aee;Yoon, Byung-Kon;Paik, Il-Young;Suh, Sang-Hoon
    • Journal of Life Science
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    • v.19 no.12
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    • pp.1750-1757
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    • 2009
  • The purpose of this study was to investigate the effects of regular walking exercise on health-related parameters in the elderly with chronic diseases - apoplexy, overweight, impaired fasting glucose, and overweight + impaired fasting glucose. A total of 85 subjects, 27, 17, 21 and 20 in apoplexy (A), overweight (O), impaired fasting glucose (IFG), overweight + impaired fasting glucose group (O_IFG), respectively, completed a 12-week walking exercise. The health-related parameters were measured before and at the completion of the exercise program including anthropometric measurements, functional physical fitness levels, blood pressure, fasting glucose, blood lipid profiles and chronic inflammatory markers (CRPs). Significant improvements in body weight, BMI, %body fat, blood pressure, all blood lipid measurements and all measured physical fitness items were shown in A; those in %body fat, TC, HDL-C and LDL-C in O; those in body weight, BMI, %body fat, fasting glucose, TC, TG and HDL-C in IFG; and those in body weight, HDL-C and LDL-C in O_IFG (p<0.05). The results of the present study demonstrated that a 12-week walking exercise brought positive effects on body weight, bloody lipid profiles, fasting glucose and functional physical fitness levels in the elderly with chronic diseases. In conclusion, this study suggested that walking regularly is very effective in lowering the risks of developing chronic diseases.

The Effects of Group Exercise on Fat Distribution, Lipid Profiles in Elderly Women (집단체조프로그램이 여성노인의 신체조성, 혈청지질에 미치는 효과)

  • Lee, Kyung-Hye;Kang, Hyun-Sook
    • The Korean Journal of Rehabilitation Nursing
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    • v.8 no.1
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    • pp.13-19
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    • 2005
  • Purpose: This study was aimed to identify the effects of group exercise on physiological functions in Elderly. Method: The design of research was one group pretest-posttest design. The subjects were sixty two elderly women persons over sixty years old to live in C-GUN, The exercise period was 12-weeks and frequency was three times per week. the exercise duration was sixty minites. In order to evaluate the effect of exercise, we measured %body fat, fat mass(FM), fat free mass(FFM), body mass index(BMI), body metabolic rate(BMR), Total Cholesterol(TC), Triglyceride(TG), high density lipoprotein-c(HDL-C), low density lipoprotein-c(LDL-C) before and after the 12 week's group exercise program. The data analyzed by the paired t-test using SPSS package. Result: There was significant difference in FFM(p=.000), BMR(p=.000), HDL-C(p=.010). There was no significant difference in weight(p=.122), %body fat(p=.062),, FM(p=.704), BMI(p=.136), TC(p=.125), TG(p=.064), LDL-C(p=.575) Conclusion: This group exercise for elderly women can be recommended as an effective nursing intervention for elderly women in a community.

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Effects of a High Protein Diet and Aerobic Exercise on Body Weight Changes and Blood Lipids in Slightly Overweight Women

  • Suh, Kyoung Yeo;Lee, Dae Taek
    • Nutritional Sciences
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    • v.8 no.1
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    • pp.28-34
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    • 2005
  • To examine the combined effects of a high-protein diet and aerobic exercise on body weight and composition and blood lipid profiles in overweight women, 30 young women were recruited and placed into three groups: The high-protein diet and exercise group (HPE), the exercise-only group (EXO) and the control group (CON) (30$\pm$3%, 27$\pm$2%, and 29$\pm$3% body fat, respectively) for an 8-week experimental period. Daily diet included 25% isolated soybean protein (>90% protein, approximately 400 kcal) combined with each subject s usual diet for the HPE group. The exercise program consisted of aerobic-type exercises undertaken >3 times/wk and for>30 min/session at 50-60% of maximal capacity. Physical fitness, body composition, serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), triglycerides (TG) and glucose were measured before and after the experiment. Maximal aerobic capacity increased by the end of experiment in both the HPE (from 27.2$\pm$3.5 to 35.l$\pm$5.9 ml/kg/min, p<0.01) and EXO (from 30.3$\pm$5.4 to 33.8$\pm$3.8 mㅣ/kg/min, p<0.05) groups. Percent body fat decreased by 3.3% (p<0.01) in the HPE group and by 1.5% (p<0.05) in the EXO group by the end of the experiment, but not in the CON group. Lower back strength and agility increased only in the HPE group. In the HPE group, TC decreased from 168$\pm$20 to 155$\pm$18 mg/dL and HDL-C increased from 57$\pm$l0 to 61$\pm$9 mg/dL in HPE (p<0.01). But TC and HDL-C did not change in the EXO and CON groups. TG and glucose did not vary among the groups. Although the EXO group showed a similar outcome to that of the HPE group, a favorable change in body composition and blood lipids as well as an improvement in aerobic capacity was more marginal in the latter group.

Laboratory Findings and Subjective Symptoms of Car Repair Workers (자동차 정비공의 혈액 및 뇨검사 소견과 자각증상에 대한 조사)

  • 이광성;이명구;조영채
    • Journal of Environmental Health Sciences
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    • v.24 no.2
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    • pp.80-87
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    • 1998
  • To evaluate the effects on health by exposure to low dose organic solvents, the author analyzed the air concentration of mixed organic solvents (toluene, xylene, butylacetate) at worker's breathing zone during painting, some laboratory findings of blood (WBC, RBC, Hb, Hct, SGOT, SGPT, TC, TG, HDL-C, LDL-C, IgG, IgM, IgA and IgE) and urine (hippuric acid, urinary protein, urobilinogen), surveyed the subjective symptoms those were obtained from 35 male workers exposed to mixed organic solvents, and 25 male workers not exposed to organic solvents who worked in car repair workshops in Taejon area from December 1, 1995, to February 29, 1996. The results were as follows: 1. The mean concentration of urinary hippuric acid of car painting worker group (organic solvent exposure group) was 0.76$\pm$ 0.21 g/l, which is significantly higher than that of non-exposed group. 2. In hematologic findings, the values of RBC, TC, LDL-C, IgG and IgE in the exposure group were significantly lower than those of the nonexposed group, but SGOT and SGPT in the exposure group were significantly higher than those of the non-exposed group. 3. Urinary hippuric acid levels showed positively correlated with toluene, urobilinogen and HDL-C levels, but those were negatively correlated with RBC, LDL-C, IgM levels. 4. Rates of the subjective symptoms such as "dizziness", "appetite loss", "weight loss", "palpitation", "chest tightness", "sore throat and eye discomfort", "tingling sense and acrodynia", "illusion or hallucination" and "decreaased motor power" were significantly higher in the exposure group than those of the non-exposed group.

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Effects of Rubus Coreanus Miq. Oil on Serum Lipids in C57BL/6J Mice (복분자씨유의 식용유지 대체가 C57BL/6J Mice의 혈청 지질에 미치는 영향)

  • Byun, Moon-Sun;Cha, Youn-Soo;Hwang, Keum-Taek;Yu, Ok-Kyeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.7
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    • pp.953-960
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    • 2015
  • This study evaluated the effects of Rubus coreanus Miq. oil on the plasma lipid profile of high fat diet (HFD)-induced obese mice. Animals were randomly divided into 4 groups (n=10). After completion of the 5-week experimental period, we measured bodyweight gain, food intake, adipose tissue mass, and plasma lipid profile. We also analyzed the activities of carnitine and superoxide dismutase (SOD) involved in ${\beta}$-oxidation and antioxidation, respectively. Our results show that HFD-induced weight gain in animals in the R. coreanus Miq. oil diet group (RCO) and corn oil diet group (CO) was significantly lower compared to animals in the HFD group; RCO supplementation had a more noticeable effect than CO. Visceral and back fat weights were lower in the RCO and CO groups while plasma HDL cholesterol (HDL-C) and HDL-C per total cholesterol [HDL-C/TC (%)] ratio were significantly higher in the RCO group. The contents of acid-soluble acylcarnitine and total carnitine as well as SOD activation were significantly higher in the RCO group, but no significant difference was observed between the RCO and CO groups. In conclusion, RCO effectively averted elevation of total body weight and fat weight in HFD-induced obese mice and promoted increased HDL-C. Therefore, R. coreanus Miq. oil might play an anti-obesity role in obese people and could be used as an effective oil supplement.

A Study on the Relationship between Levels of Serum Lipids and Food Habits of College Students (남녀 대학생들의 혈청지질수준, 신체계측치와 식습관과의 관계에 관한 연구)

  • 변기원
    • The Korean Journal of Food And Nutrition
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    • v.7 no.4
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    • pp.284-296
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    • 1994
  • This study was undertaken to examine the levels of serum lipids and lipoproteins of college students and the correlations between serum lipid levels and food habits. 202 college students(99 males and 103 females) were selected as subjects for this study during November, 1993. The mean height and weight were 173.2 cm, 63.7 kg for males and 159.4 cm, 50.8 kg for females, respectively. The mean serum TC, LDL-C, HDL-C, TG levels were 172.2, 103.4, 52.3 and 82.3 for males and 182.4, 111.6, 56.3 and 72.5 mg 161 for females, respectively. Serum lipid levels of males were significantly lower than those of females except TG. There was no significant difference In TG levels between males and females. Food habit scores of females were significantly higher than those of males. The significantly different items between males and females were numbers of daily meal intake, duration of meal intake, regular daily Intakes of cereals, fruits, vegetables and animal fat, exercise, alcohol intake and smoking. Food habit score of Items except exercise in females were higher than those of items in males. LDL-C and LPH were positively correlated with food habit score. TC and LDL-C were positively correlated with eating-out, alcohol intake, smoking but negatively correlated with numbers of daily meal intake. HDL-C was positively correlated with overeating, but negatively correlated with cholesterol intake. There was no significant correlation between TG and food habit items. Regular meal intake was positively correlated to LPH by having a negative correlation with HDL-C in males and regular daily intake of cereal was positively correlated to LPH by haying a positive correlation with LDL-C in females. There were significant correlation between food habits and anthropometric measurements. Height and weight were positively correlated with daily meal intake and exercise but negatively correlated with duration of meal intake, daily intakes of cereals, vegetables fruits and animal fat, smoking, alcohol intake. Smoking was negatively correlated with height and weight in males, over-eating was negatively correlated with height in females. Finally this study showed an interesting results that balanced intake of five basic food groups were positively correlated with weight in males but with height in females.

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The Effect of Exercise Program for Falls Prevention on Balance, Falls Efficacy, Blood Pressure and Blood Lipids in the Elderly Women (낙상예방 운동프로그램이 노인여성의 균형, 낙상효능감과 혈압 및 혈중지질에 미치는 영향)

  • Kim, Young-min
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.21 no.2
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    • pp.7-14
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    • 2015
  • Purpose: The purpose of this study was to investigate the effects of falls prevention exercise program to balance, falls efficacy, blood pressure and blood lipids in the elderly females. Methods: A total of twenty-six elderly women participated in this study. All subjects participated in exercise program based on pelvic stabilization and balance training on two times a week for twelve weeks. They were measured about Berg balance scale (BBS), Time up and go (TUG), Functional reach test (FRT), Sit to stand (STS) for balance, falls efficacy scale-international (FES-I) for falls efficacy, systolic blood pressure (SBp), diastolic pressure (DSp) for blood pressure, and total cholesterol (TC), triglyseride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) for blood lipids. Results: There were significant improvements of BBS (p<.05), TUG (p<.001) FRT (p<.01), and STS (p<.001) in the balance after exercise program. There was significant improvements in FES-I (p<.001) in the falls efficacy, There were no statistical differences of SBp and DSp in the blood pressure. There were no statistical differences of TC, TG, HDL-C, and LDL-C in the blood lipids. Conclusions: Falls prevention exercise program was meaningful increasing balance ability and falls efficacy.

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