• 기술표준
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• 통권88호
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• pp.41-43
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• 2009

• 기술표준
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• 통권84호
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• pp.35-36
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• 2009

• 정보처리학회논문지C
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• 제12C권1호
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• pp.121-128
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• 2005

기존 TCP 기술은 송${\cdot}$수신측에 각각 고정된 크기의 버퍼를 할당하기 때문에 높은 대역폭(High-Bandwidth) 및 큰 전송지연(High Delay)을 가진 통신에는 적합하지 못하다. 따라서 종단간의 TCP 처리량을 개선하기 위해 통신망 상황에 따라 자동으로 TCP 버퍼를 조절하려는 시도가 있어왔다. ATBT(Automatic TCP Buffer Tuning)에서 송신측은 현재의 혼잡 제어 윈도우(CWND)의 값에 따라 송신 버퍼 크기를 조절하고 수신측은 운영체제가 정해ens 최대 크기의 TCP 버퍼 값으로 수신 버퍼 크기를 고정한다. DRS(Dynamic Right Sizing) 에서는 이전에 수신한 TCP 데이터의 두 배를 현재 송신할 TCP 데이터라고 예측함으써, TCP 수신측은 단순히 이에 따라 수신 버퍼 크기를 동적으로 변화시킨다. 그렇지만 TCP 세그먼트의 손실 가능성으로 인해 정확히 두 배로 버퍼 크기를 변화시킬 필요는 없다. 따라서 우리가 제안한 패킷 손실률에 기반한 효율적인 TCP 버퍼 조절 알고리즘(TBT-PLR:TCP Buffer Tuning Algorithm based on Packet Loss Ratio)은 TCP 송신측에는 ATBT 방법을 TCP 수신측에는 TBT-PLR 방법을 적용하였다. 실제 TCP 성능을 테스트하기 위해서 리눅스 커널 2.4.18을 수정하여 구현하였으며 기존의 고정된 크기의 TCP 버퍼를 가진 경우와 버퍼 크기가 동적으로 변하는 TBT-PLR을 적용한 경우를 비교하였다. 결과적으로, TCP 연결들간의 균형있는 메모리 사용으로 인해 성능 향상을 얻을 수 있었다.

• Journal of the korean society of oceanography
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• 제33권3호
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• pp.90-99
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• 1998

Butyltin and phenyltin residues were quantified in seawater and biota of the Chinhae Bay System, Korea in 1995. Butyltin compounds were detected in all seawater and biota samples, whereas phenyltin compounds were found only in the biota samples. Tributyltin (TBT) concentrations in seawater ranged from < 8-35 ng Sn/l. Tributyltin concentrations in Crassostyea gigas and Thais clavigera ranged from 95-885 and 23-414 ng Sn/g, respectively, Triphenyltin(TPhT) concentrations in each species ranged 155-678 and 46-785 ng Sn/g, respectively. Spatial distribution of TBT was closely related to boating and dry-docking activities. However, spatial distribution of TPhT was not consistent with that of TBT. The biological concentration factor for TBT in C. gigas was about 25000 that is four times greater than that of T. clavigera. Butyl- to phenyltin concentration ratio was greater than one in C. gigas, but that in T. clavigera was less than one. Major tissues of C. gigas also showed different accumulation patterns for butyl- and phenyltin compounds. Furthermore, 19 and 28% of total body burdens of TBT and TPhT were found in gonadal mass of C. gigas just prior to spawning.

• 한국발생생물학회지:발생과생식
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• 제16권4호
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• pp.289-294
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• 2012

Gene expressions of cytochrome P4501A (CYP1A), aryl hydrocarbon receptor (AhR) and vitellogenin (Vg) by endocrine disruptors, benzo[${\alpha}$]pyrene (B[a]P) and tributyltin (TBT) were examined in cultured eel hepatocytes which were isolated from eels treated previously with B[a]P (10 mg/kg) or estradiol-$17{\beta}$ (20 mg/kg) in vivo, and the relationship between CYP1A, AhR and Vg genes were studied. When the cultured eel hepatocytes were treated with B[a]P ($10^{-6}-10^{-5}M$) the gene expressions of CYP1A and AhR were enhanced in a concentration-dependent manner. However, when treated with TBT ($10^{-9}-10^{-5}M$) the gene expressions of CYP1A and AhR were suppressed at high concentrations ($10^{-6}-10^{-5}M$), while having no effects at low concentrations ($10^{-9}-10^{-7}M$). Gene expression of Vg was also suppressed by TBT in a concentration-dependent manner in cultured eel hepatocytes which was previously treated in vivo with estradiol-$17{\beta}$.

• Journal of Pharmaceutical Investigation
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• 제38권5호
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• pp.295-302
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• 2008

In the present study, we examined the changes of uptake and efflux of taurine under various conditions inducing oxidative stress using rat conditionally immortalized syncytiotrophoblast cell line, TR-TBT cell, as blood-placental barrier in vitro model. In addition, we identified the characteristics of taurine transport in TR-TBT cells including general features, besides effect of calcium ion on taurine transport. Taurine uptake showed time, $Na^+$ and $Cl^-$ dependency, and was decreased by PKC activator in TR-TBT cells. Also, calcium free condition decreased taurine uptake and evoked taurine efflux in the cells. Oxidative stress induced the change of taurine transport in TR-TBT cells, but the changes were different depending on the types of stimulation inducing oxidative stress. The taurine uptake was increased by TNF-$\alpha$, LPS and DEM stimulation but decreased by $H_2O_2$ and NO stimulation. Also, the taurine efflux was regulated by TNF-$\alpha$ stimulation. In conclusion, the taurine transport through the blood-placental barrier was regulated in oxidative stress conditions, and these results demonstrated that oxidative stress affected the taurine supplies to fetus and taurine level of fetus.

• 대한물리치료과학회지
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• 제17권1_2호
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• pp.33-39
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• 2010

Purpose: The purpose of this study was to analyze the effects of a balance training program using the TARGET Balance Trainer(TBT), which utilizes a visual target, on the balancing ability of normal, healthy individuals. Methods: Twelve healthy female students with an average of 20.7 years(SD=0.25), were participated in this study. They were randomly divided into two groups(6 subjects in each group); experimental group, control group. The experimental group underwent a 3-week training program using the TBT, while the control group trained using only a dynamic air cushion(DAC). Results: Compared to those who trained using only the DAC, participants who trained with the TBT had a smaller difference between the weights distributed(N) to their left and right foot while normal standing with their eyes open. The TBT group also showed a smaller discrepancy between the weights distributed(N) to their left and right sides while standing on one leg with their eyes open, and also with their eyes closed by eye band. Conclusions: TBT is effective to reduce the degree of weight shifting between left and right side in each group. This study is expected to provide a model for future clinical studies.

• 한국환경과학회지
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• 제20권2호
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• pp.163-174
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• 2011

Butyltin compounds in seawater, sediments and organisms inside Jeju Harbor of Jeju Island, Korea, were quantitatively determined to assess the extent of contamination and to evaluate the bioaccumulation in Thais clavigera (gastropod), Liolophura japonica and Cellana nigrolineata. In addition, imposex in T. clavigera was used to assess the sublethal effect of tributyltin compounds and its usage as a specific biomarker for these compounds was also studied. The main species in seawater was tributyltin (TBT) in March and June, monobutyltin (MBT) in August, but in sediments and organisms it was dibutyltin (DBT) and TBT, respectively, irrespective of survey time. TBT, the most toxic to aquatic organisms among BTs, was found at concentrations which were sufficient to have a serous effect on the sensitive organisms upon chronic exposure. The high correlations (r>0.7) between BTs indicated that DBT and MBT were mainly degraded from TBT based on antifouling paints and their sources were negligible. The sedimentary organic matters have little influence on the distribution of BTs in marine environment and the lipid content in T. clavigera showed a significant correlation with TBT concentrations. Measurement of imposex T. clavigera was expected to be a very helpful tool for preliminary survey of BTs prior to trace analysis of those.

• Biomolecules & Therapeutics
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• 제22권1호
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• pp.68-72
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• 2014

When chemotherapy is administered during pregnancy, it is important to consider the fetus chemotherapy exposure, because it may lead to fetal consequences. Paclitaxel has become widely used in the metastatic and adjuvant settings for woman with cancer including breast and ovarian cancer. Therefore, we attempted to clarify the transport mechanisms of paclitaxel through blood-placenta barrier using rat conditionally immortalized syncytiotrophoblast cell lines (TR-TBTs). The uptake of paclitaxel was time- and temperature-dependent. Paclitaxel was eliminated about 50% from the cells within 30 min. The uptake of paclitaxel was saturable with $K_m$ of $168{\mu}M$ and $371{\mu}M$ in TR-TBT 18d-1 and TR-TBT 18d-2, respectively. [$^3H$]Paclitaxel uptake was markedly inhibited by cyclosporine and verapamil, well-known substrates of P-glycoprotein (P-gp) transporter. However, several MRP substrates and organic anions had no effect on [$^3H$]paclitaxel uptake in TR-TBT cells. These results suggest that P-gp may be involved in paclitaxel transport at the placenta. TR-TBT cells expressed mRNA of P-gp. These findings are important for therapy of breast and ovarian cancer of pregnant women, and should be useful data in elucidating teratogenicity of paclitaxel during pregnancy.

• 무역학회지
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• 제44권2호
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• pp.287-305
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• 2019

The export of agricultural, fisheries, and food products acts as an engine of growth for developing countries in particular. However, exporting these items is easier said than done since issues of certification and inspection, so-called technical barriers to trade (TBT) and sanitary and phytosanitary measures (SPS), in developed markets have worked as major obstacles for exports. This paper examines the institutional aspects and recent trends of South Korea's TBT/SPS-related cases against exporting firms of the developing countries. We suggest a win-win partnership model that can promote cooperative synergies between Korea and developing employing trade-related technical cooperation or ODA (Official Development Aid). Technical cooperation such as the provision of on-spot field consulting services on TBT/SPS-related issues for exporting firms and Korean OEM firms of developing countries can lead to mutual gains. This cooperative partnership can create gains from "the trade-development nexus" for both sides while promoting sustainable trade and investment relationships between Korea and developing countries.