• 한국환경보건학회지
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• 제23권4호
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• pp.1-8
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• 1997

The aquatic animals of Tan stream were composed of 46 species, 28 families, 11 orders, 6 classes in 4 phyla during the survey period of April, 1996 to December, 1996. They were composed of 31 species in aquatic insecta, 6 species in annelida, 3 species in mollusca, 1 species in crustacea, and 5 species in fishes, respectively. Major dominant species in Tan stream were Chironomidae sp.1, Chironomidae sp.2, Chironomidae sp.3, Tubufucidae sp.1, Physa acuta and hirudo niponica. Dominance indices of benthic macroinvertebrates ranged highly from 95.74 to 100.00% at lower stream(site 4), but ranged 50.00 to 95.85% at site 1 through site 3. The aquatic animals ranged from 25 to 32 species at site 1 through site 3, but they were only 3 species at site 4 for survey period. Tan stream in the light of urban stream ecosystem has a little less riffle areas and hydrophyte areas by cementation of riparian area and channel type of water course. Therefore, the species of aquatic animals in Tan stream decreased because of deterioration of water quality according to reduction of self-purifcation ability and loss of microhabitat according to reduction of hydrophyte areas and riparian areas. The tendency of decreasing species of aquatic animals appeared seriously at lower stream From drive licence test authority at Kangnam-ku, Seoul to conjunction point of the Han river.

• 한국의사학회지
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• 제36권1호
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• pp.11-21
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• 2023

Objectives : This paper is to find the meaning of Tan pulse at Chon and Cheok area due to pathological situation at Yang-gyo vessel & Yin-gyo vessel in Qikooujiudamai Diagnosis. Methods : In terms of Qikooujiudamai, the position to diagnose the Yang-gyo vessel & Yin-gyo vessel is Chon and Cheok position and the pulse is Tan pulse. To find the meaning of Tan pulse, wi-gi was analyzed. Then the correlation between Yang-gyo vessel & Yin-gyo vessel with wi-gi was analyzed to find the meaning of Tan pulse. Results & Conclusion : Yang-gyo vessel & Yin-gyo vessel have close connection with Wi-gi and its rise and fall is expressed by sleep. The Tan pulse means that Yang-gyo vessel & Yin-gyo vessel is in pathological situation by Wi-gi. By knowing the Qikooujiudamai's meaning, we can use acupucture treatment and medicine more precisely.

• BMB Reports
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• 제40권5호
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• pp.625-635
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• 2007

The enzyme squalene synthase (EC 2.5.1.21) catalyzes a reductive dimerization of two farnesyl diphosphate (FPP) molecules into squalene, a key precursor for the sterol and triterpene biosynthesis. A full-length cDNA encoding squalene synthase (designated as TcSqS) was isolated from Taxus cuspidata, a kind of important medicinal plants producing potent anti-cancer drug, taxol. The full-length cDNA of TcSqS was 1765 bp and contained a 1230 bp open reading frame (ORF) encoding a polypeptide of 409 amino acids. Bioinformatic analysis revealed that the deduced TcSqS protein had high similarity with other plant squalene synthases and a predicted crystal structure similar to other class I isoprenoid biosynthetic enzymes. Southern blot analysis revealed that there was one copy of TcSqS gene in the genome of T. cuspidata. Semi-quantitative RT-PCR analysis and northern blotting analysis showed that TcSqS expressed constitutively in all tested tissues, with the highest expression in roots. The promoter region of TcSqS was also isolated by genomic walking and analysis showed that several cis-acting elements were present in the promoter region. The results of treatment experiments by different signaling components including methyl-jasmonate, salicylic acid and gibberellin revealed that the TcSqS expression level of treated cells had a prominent diversity to that of control, which was consistent with the prediction results of TcSqS promoter region in the PlantCARE database.

• The Korean Journal of Physiology and Pharmacology
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• 제26권5호
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• pp.335-345
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• 2022

Pyroptosis is an inflammatory form of programmed cell death that is linked with invading intracellular pathogens. Cardiac pyroptosis has a significant role in coronary microembolization (CME), thus causing myocardial injury. Tanshinone IIA (Tan IIA) has powerful cardioprotective effects. Hence, this study aimed to identify the effect of Tan IIA on CME and its underlying mechanism. Forty Sprague-Dawley (SD) rats were randomly grouped into sham, CME, CME + low-dose Tan IIA, and CME + high-dose Tan IIA groups. Except for the sham group, polyethylene microspheres (42 ㎛) were injected to establish the CME model. The Tan-L and Tan-H groups received intraperitoneal Tan IIA for 7 days before CME. After CME, cardiac function, myocardial histopathology, and serum myocardial injury markers were assessed. The expression of pyroptosis-associated molecules and TLR4/MyD88/NF-κB/NLRP3 cascade was evaluated by qRT-PCR, Western blotting, ELISA, and IHC. Relative to the sham group, CME group's cardiac functions were significantly reduced, with a high level of serum myocardial injury markers, and microinfarct area. Also, the levels of caspase-1 p20, GSDMD-N, IL-18, IL-1β, TLR4, MyD88, p-NF-κB p65, NLRP3, and ASC expression were increased. Relative to the CME group, the Tan-H and Tan-L groups had considerably improved cardiac functions, with a considerably low level of serum myocardial injury markers and microinfarct area. Tan IIA can reduce the levels of pyroptosis-associated mRNA and protein, which may be caused by inhibiting TLR4/MyD88/NF-κB/NLRP3 cascade. In conclusion, Tanshinone IIA can suppress cardiomyocyte pyroptosis probably through modulating the TLR4/MyD88/NF-κB/NLRP3 cascade, lowering cardiac dysfunction, and myocardial damage.

• Korean Journal of Radiology
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• 제21권5호
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• pp.629-631
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• 2020

• 대한원격탐사학회지
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• 제36권2_2호
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• pp.325-335
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• 2020

식생 높이는 높이-탄소식생량 추정 모델을 이용하여 식생탄소량은 측정하는데 사용된다. 접근이 힘든 지역의 망그로브 생태는 현장 자료를 취득하는데 어려움이 있으며, 제한적인 현장 자료로부터 대규모 식생량 및 탄소양모델을 연구하는데 한계점이 있다. 능동형과 수동형 원격탐사 기법이 망그로브 식생 연구에 활용되고 있으나, 공간 해상도의 한계로 인해 작은 규모의 특징을 감지하는데 문제가 있다. 이 논문에서는 TanDEM-X 자료를 이용하여 SRF 지역 12 m 공간 해상도 망그로브 식생 높이 분포를 측정하였다. 단일 편파를 사용하였지만, 수면과 망그로브 식생 사이에서 일어나는 이중 반사 현상을 이용하여 망그로브 숲 지역의 수면의 높이를 측정하여 식생 높이를 측정하는 새로운 인버젼 모델을 사용하였다. TanDEM-X 식생 높이 결과를 모자이크하여 SRF 전 지역의 대규모 식생 높이 지도를 제작하였다. 현장 자료와 검증한 결과 상관계수 0.83, RMSE 0.84 m로 나타났다. 전 세계를 관측한 TanDEM-X 자료를 이용하면, 고해상도 글로벌 망그로브 식생 높이 지도 제작이 가능함을 보여주었다. 이러한 결과들은 망그로브 식생탄소량 및 탄소 순환을 이해하는데 중요한 역할을 할것으로 기대된다.

• 대한화학회지
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• 제32권1호
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• pp.15-21
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• 1988

반양성자성 용매인 아세토니트릴 중에서 1-(2-thiazolylazo)-2-naphthol (이하 TAN으로 줄임)의 폴라로그래프적 성질을 조사하였다. 직류폴라로그램으로부터 환원전류의 유형과 양성자 주게 인물의 첨가에 따른 영향을 검토하였다. 그리고 환원반응에 관여한 전자수는 정전위분해법으로 구하였다. 또 일정전위전해생성물의 UV-Vis Spectrum과 IR-Spectrum으로부터 전해생성물을 확인하였다. 이상의 실험결과로부터 아세토니트릴 용매중에서 TAN은 1전자 4단계의 환원과정을 거쳐 최종적으로 아민화합물이 됨을 알았다. 또 각 환원과정은 모두 가역적이었으며, 각 단계의 환원전류는 확산지배적이었다.

• 한국멀티미디어학회논문지
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• 제16권3호
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• pp.269-280
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• 2013

본 논문에서 망막 질환 요인간의 의존도 분석을 위해 효율적인 분류기를 활용할 수 있는 방안을 제시하였다. 먼저 여러 베이지안 네트워크 중에서 TAN (Tree-Augmented Naive Bayesian Network), GBN(General Bayesian Network)과 Markov Blanket으로 특징축소된 GBN과의 분류성능과 예측정확률을 비교분석하였다. 그리고 처음으로, 높은 성능을 보인 TAN을 망막 질환 임상데이터의 의존도 분석에 적용하였다. 의존도 분석 결과, 망막 질환의 진단과 예후 예측에 활용의 가능성을 보였다.

• The Plant Pathology Journal
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• 제37권4호
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• pp.339-346
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• 2021

Prevalence of tan spot of wheat caused by the fungus Pyrenophora tritici-repentis has become more prevalent in Oklahoma as no-till cultivation in wheat has increased. Hence, developing wheat varieties resistant to tan spot has been emphasized, and selecting pathogen isolates to screen for resistance to this disease is critical. Twelve isolates of P. tritici-repentis were used to inoculate 11 wheat cultivars in a greenhouse study in splitplot experiments. Virulence of isolates and cultivar resistance were measured in percent leaf area infection for all possible isolate x cultivar interactions. Isolates differed significantly (P < 0.01) in virulence on wheat cultivars, and cultivars differed significantly in disease reaction to isolates. Increased virulence of isolates detected increased variability in cultivar response (percent leaf area infection) (r = 0.56, P < 0.05) while increased susceptibility in cultivars detected increased variance in virulence of the isolates (r = 0.76, P < 0.01). A significant isolate × cultivar interaction indicated specificity between isolates and cultivars, however, cluster analysis indicated low to moderate physiological specialization. Similarity in wheat cultivars in response to pathogen isolates also was determined by cluster analysis. The use of diverse isolates of the fungus would facilitate evaluation of resistance in wheat cultivars to tan spot.

• 한국수산과학회지
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• 제53권6호
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• pp.918-924
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• 2020

This study investigated diurnal fasting and postprandial total ammonia nitrogen (TAN) excretion rates in juvenile Oplegnathus fasciatus (rock bream; mean body weight 45.8±1.1 g) at three temperatures (15, 20, and 25℃) in a recirculating system (three replicates). The fish were hand-fed twice daily (09:00 and 17:00 h) with commercial food (46.7% protein) until satiation. The results showed that the fasting and postprandial TAN excretion rates were temperature-dependent. The mean hourly rates were 7.7 (15℃), 10.2 (20℃), and 11.9 (25℃) mg kg fish-1 h-1 for fasting and 34.0 (15℃), 47.8 (20℃), and 60.2 (25℃) mg kg fish-1 h-1 for postprandial. At each temperature, two postprandial TAN excretion peaks were observed 2-4 h after feeding; the second peak was always higher. The TAN loss to nitrogen consumption ratio was 41.1-46.8 % and increased significantly with increasing temperature. Temperature affected fasting and postprandial TAN excretion in juvenile rock bream, providing insight for culture management.