• Title/Summary/Keyword: TAC temperature

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The age dating for an archaeological sample using pre-dose effect (Pre-dose effect를 이용한 고고학 시료의 연대측정)

  • Kim, Myung-Jin;Hong, Duk-Geun
    • Analytical Science and Technology
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    • v.18 no.4
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    • pp.329-337
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    • 2005
  • TL dating using pre-dose effect is concerned with the sensitivity increase of $110^{\circ}C$ TL peak in quartz following the pre-exposure of irradiation (pre-dose) in antiquity and heating to thermal activation temperature. Using the multiple activation (MA) method for determining an equivalent dose, the activation temperature was selected to $500^{\circ}C$ and the region of interest was selected from $85^{\circ}C$ to $105^{\circ}C$ on quartz sample from archaeological remains, roof-tile kiln. which was excavated at Chudong-Ri cultural site. It was concluded that the resultant date was determined to the age of $1725{\pm}25years$ AD (l ${\sigma}$ SD), which had more improved precision considering with e radiocarbon dates and was in good agreement with the age derived by archaeological assessment. Also it was concluded that the pre-dose dating should contribute significantly to future archaeological dating work in the range of the last 2000 years.

Risk of Treatment Related Death and Febrile Neutropaenia with Taxane-Based Adjuvant Chemotherapy for Breast Cancer in a Middle Income Country Outside a Clinical Trial Setting

  • Phua, Chee Ee;Bustam, Anita Zarina;Yusof, Mastura Md.;Saad, Marniza;Yip, Cheng-Har;Taib, Nor Aishah;Ng, Char Hong;Teh, Yew Ching
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4623-4626
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    • 2012
  • Background: The risk of treatment-related death (TRD) and febrile neutropaenia (FN) with adjuvant taxane-based chemotherapy for early breast cancer is unknown in Malaysia despite its widespread usage in recent years. This study aims to determine these rates in patients treated in University Malaya Medical Centre (UMMC). Patients and Methods: Patients who were treated with adjuvant taxane-based chemotherapy for early breast cancer stages I, II or III from 2007-2011 in UMMC were identified from our UMMC Breast Cancer Registry. The TRD and FN rates were then determined retrospectively from medical records. TRD was defined as death occurring during or within 30 days of completing chemotherapy as a consequence of the chemotherapy treatment. FN was defined as an oral temperature > $38.5^{\circ}C$ or two consecutive readings of > $38.0^{\circ}C$ for 2 hours and an absolute neutrophil count < $0.5{\times}10^9/L$, or expected to fall below $0.5{\times}10^9/L$. Results: A total of 622 patients received adjuvant chemotherapy during this period. Of these patients 209 (33.6%) received taxane-based chemotherapy. 4 taxane-based regimens were used namely the FEC-D, TC, TAC and AC-PCX regimens. The commonest regimen employed was the FEC-D regimen accounting for 79.9% of the patients. The FN rate was 10% and there was no TRD. Conclusion: Adjuvant taxane-based chemotherapy in UMMC for early breast cancer has a FN rate of 10%. Primary prophylactic G-CSF should be considered for patients with any additional risk factor for FN.

Effects of Weed Control on Pseudocercospora vitis and Fruit Characteristics in Campbell Early Vineyard (캠벨얼리 포도원에서 잡초관리 방법이 갈색무늬병 및 과실특성에 미치는 영향)

  • Kim, Sun-Kook;Choi, Won-Ho;Lee, Seok-Ho;Lee, Yun-Sang;Yoon, Changmann;Hong, Seong-Tac
    • Korean Journal of Organic Agriculture
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    • v.23 no.4
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    • pp.897-909
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    • 2015
  • This study was conducted to evaluate the effect of weed control on disease incidence, plant growth and fruit quality, and to provide effective method to farmers at the vineyard. At the raincoat greenhouse cultivating 'Campbell Early', several weed controlling methods were compared to the control. Mean temperature of plots between soil covering (C.B., W.F., S.N., P.F. and R.H.) and non soil covering (M.W.2, M.W.3 and U.T.) were similar with $26.2^{\circ}C$ (July) and $25.8^{\circ}C$ (Aug.), but humidity of soil covering was sharply decreased in late-July under 40%. Soil water were all higher in soil covering plots than that of non-soil covering, however, soil temperature was recorded lower in soil covering plots. Disease incidence of Peudocercospora vitis according to soil coverings had effect on black plastic film mulching by decreasing grapevine leaf spot to 85% in July, 69% in August, compared to the control, with showing the smallest lesion incidence in FMB. Among growth characters, internode length and internode width of black plastic film mulching was higher than that of the control. SPAD value of black plastic film mulching was recorded the highest. It was not significant among the treatments, but brix was recorded highly in black plastic film mulching with $14{\sim}15^{\circ}Brix$.

Optimization of the Extraction Process and Antioxidant Capacity of Coptis chinensis Franch Extract through Cluster Analysis (클러스터 분석을 이용한 황련 추출물 항산화 활성 최적화 추출공정)

  • Fu, Minmin;Xuan, Song Hua;Park, Soo Nam
    • Applied Chemistry for Engineering
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    • v.29 no.5
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    • pp.604-612
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    • 2018
  • Coptis chinensis Franch is a valuable traditional oriental medicinal plant used for the treatment of various diseases. The major factors affecting the content of bioactive compounds and the relationship between bioactive compounds and antioxidant capacities of Coptis chinensis Franch were poorly understood. Thus, effects of the solvent, temperature, and extraction time on the extraction yields of bioactive compounds and the antioxidant activity of C. chinensis Franch extracts were investigated in this work. Our cluster analysis indicated that the hydroalcoholic solvent (50% ethanol : 50% water) at $35^{\circ}C$ for 30 min (extract time) was the best extraction condition for a factory use because the highest level of bioactive compounds and antioxidant activities was achieved. Multiple linear regression analysis revealed that total phenolic content (TPC) contributed to the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity, while both total alkaloid content (TAC) and total flavonoid content (TFC) were responsible for ferric reducing antioxidant power (FRAP) activity. These results indicated that extraction conditions controlled the yield of bioactive compounds and the antioxidant activity of C. chinensis Franch, which can provide important information for the industrial extraction.