• International Journal of Industrial Entomology and Biomaterials
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• 제20권2호
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• pp.61-67
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• 2010

The bivoltine tropical tasar ecoraces of Antheraea mylitta Drury produces cocoons for seed production under seed crop rearing (July-August with $22{\sim}30^{\circ}C$ temperature and 50~70% relative humidity) and for silk production under commercial crop rearing (September-December with $17{\sim}27^{\circ}C$ temperature and 60~80% relative humidity). To consider the impact of hybrid vigour on egg, larva, cocoon and silk related commercial traits, the $F_1$ hybrids made among Daba, Jata and Raily ecoraces were assessed successively for three years. The hybrid vigour in the $F_1$ hybrid of Daba$\times$Jata ($T_7$) was positive for egg fertility (+23.1%), shell weight (+25.6%), silk yield (+79.0%) and filament length (+68.1%), with filament of high denier (11.98d) and reduced larval span (-7.1%). The Jata$\times$Daba ($T_8$) hybrid has shown negative heterosis in egg fertility (-8.0%) compared to the other F1 hybrids, Daba$\times$Raily ($T_9$) and Raily$\times$Daba ($T_{10}$), when they rise simultaneously during the commercial crop season. The better performance of parental ecoraces ($T_4$ to $T_6$) in their commercial traits during commercial crop over parents of seed crop ($T_1$ to $T_3$) and the superior performance of $F_1$ hybrids ($T_7$ to $T_{10}$) over parents of commercial crop ($T_4$ to $T_6$) during commercial crop season indicates the apparent hybrid vigour in tasar $F_1$ hybrids. As the Daba$\times$Jata ($T_7$) and Jata$\times$Daba ($T_8$) $F_1$ hybrids have shown highest hybrid vigour, their rearing during commercial crop can optimize the silk productivity and commercial sustenance of the tasar silk industry.

• Nuclear Medicine and Molecular Imaging
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• 제43권4호
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• pp.323-329
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• 2009

목적: 방사면역측정법 및 면역방사계수법은 매 실험마다 표준용액을 넣고 표준곡선에 대비하여 결과를 산출하는 batch assay가 일반화되어 있다. 비용과 시간에 대한 효율성을 증가 시키기 위해서는 선행 표준 곡선을 이용하여 검사를 진행하는 random assay의 적용이 요구된다. 방사면역측정법 및 면역방사계수법에서 자동분주기를 이용한 random assay적용 가능성을 평가 하기 위해 본 연구를 수행하였다. 대상 및 방법: Triiodothyronine (T3), free thyroxine (fT4), Prostate specific antigen (PSA), Carcinoembryonic antigen (CEA) 4가지 항목을 대상으로 하였으며 각 검사별 20명의 환자 검체를 이용하였다. 각 검사 항목별로 표준곡선을 얻기 위해 3시간 간격으로 4회 측정한 표준용액의 분당계수값(counter per minute, cpm)을 측정하였다. 이를 Friedman test를 이용하여 비교하여 검사시 마다 얻는 표준 곡선간의 차이를 평가하였다. 각 검사별 저, 중, 고농도의 대조 용액을 이용하여 5회 측정하고 이를 Friedman test를 이용하여 비교하여 측정 내 정밀도를 평가하였다. 각 검사별 저, 중, 고농도의 대조용액을 batch assay와 자동분주기를 이용한 random assay로 3시간 간격으로 각각 4회 측정하였다. 측정값을 바탕으로 평균, 표준 편차, 변이계수를 구하고 Wilcoxon test를 이용하여 비교하여 assay 방법에 따른 차이를 비교하였다. 두 assay간에 일치도(agreement)를 평가하기 위해 두 assay의 측정값 사이에 급내상관계수(Intraclass correlation coefficient, ICC)와 상관계수를 계산하였다. 결과: 모든 검사항목에서 표준 용액의 분당계수값은 측정 간에 통계적으로 유의한 차이가 없었다. T3, fT4, PSA, CEA 검사항목마다 측정한 저, 중, 고농도별 측정 내 변이계수는 T3(3.6%, 2.6%, 0.9%), fT4(4.5%, 1.1%. 1.3%), PSA(3.9%, 3.1%, 1.2%), CEA(5.0%, 4.8%, 7.6%)였다. 검사 항목별 측정방법에 따른 대조 용액을 이용한 표준 곡선의 측정 간 정밀도 평가에서 두 검사 방법간에 유의한 차이가 없었다. 각 검사항목별로 20명의 환자 검체에서 측정한 측정 간 변이계수(inter-assay precision)의 평균과 표준편차 값은 batch assay로 시행했을 때 각각 3.2$\pm$1.7%, 3.9$\pm$2.1%. 7.1$\pm$6.2%, 11.2$\pm$7.2%였고 random assay로 측정하였을 때는 2.7$\pm$1.7%, 4.8$\pm$3.1%, 3.6$\pm$4.8%, 7.4$\pm$6.2였다. Batch assay와 random assay는 서로 높은 일치도를 보였다. 측정한 급내상관계수(Intraclass correlation coefficient)는 T3, fT4, PSA, CEA 각각 0.9968, 0.9973. 0.9996, 0.9901였다. Batch assay로 측정한 값과 자등분주기를 이용한 random assay로 측정한 값 사이에 상관 계수(R$^2$)는 T3, fT4, PSA, CEA 각각 0.9924, 0.9974, 0.9994, 0.9989(p<0.005)로 모두 강한 상관관계를 보였다. 결론: T3, fT4, PSA, CEA 4가지 항목의 방사면역측정 법 (Radioimmunoassay)에서 기존의 batch assay와 자동분주기를 이용한 random assay간에 일치도와 상관성이 높았다. 결론적으로 자동분주기를 이용한 random assay를 방사면역측정법 및 면역방사계수법에 적절히 이용할 수 있을 것으로 생각된다.

• BMB Reports
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• 제48권7호
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• pp.369-370
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• 2015

Actin dynamics is critical for the formation and sustainment of the immunological synapse (IS) during T cell interaction with antigen-presenting cells (APC). Thus, many actin regulating proteins are involved in spatial and temporal actin remodeling at the IS. However, little is known whether or how actin stabilizing protein controls IS and the consequent T cell functions. TAGLN2 − an actin-binding protein predominantly expressed in T cells − displays a novel function to stabilize cortical F-actin, thereby augmenting F-actin contents at the IS, and acquiring leukocyte function-associated antigen-1 activation following T cell activation. TAGLN2 also competes with cofilin to protect F-actin in vitro and in vivo. During cytotoxic T cell interaction with cancer cells, the expression level of TAGLN2 at the IS correlates with the T cell adhesion to target cancer cells and production of lytic granules such as granzyme B and perforin, thus expressing cytotoxic T cell function. These findings identify a novel function for TAGLN2 as an actin stabilizing protein that is essential for stable immunological synapse formation, thereby regulating T cell immunity. [BMB Reports 2015; 48(7): 369-370]

• 한국치위생학회지
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• 제3권1호
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• pp.1-12
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• 2003

The purpose of this study was to verify the reliability of the instrument and to analyze the contents of the humor. This study was conducted from December 16th, 2002 to January 13th, 2003, centering on Busan Dental Hospital & public health service. A total of 193 questionnaires was distributed for the survey. The result were as followings: 1. There were significant differences in humor values concerning age(F=1l.44, p=0.000), marriage(t= -3.556, p=0.000), education(F=14.83, p=0.000), clinical carrier(F=9.99, p=0.000), status(F=5.83, p=0.001), working place(F=7.39, p=0.000), and living parents(F=3.65, p=0.014). Humor values were higher for over-forties, married dental hygienists, public health service worker and no living parents. 2. There were no Significant correlation between stress and the dental hygienist's humor values. 3. There were significant differences in humor values concerning sources of the dental hygienist's humor. Data related "book/mass media"(t=-6.32, p=0.000), "conversation" (t=-12.05, p=0.000) and "daily life"(t=-10.33, p=0.000) are examples of these sources. 4. There were no significant differences in humor values concerning the dental hygienist's humor degree related frequency of used humor. 5. There were significant differences in humor values concerning the type of humor used, "word humor"(t=-7.00, p=0.000), "imitation"(t=2.68, p=0.008), "adequate situation" (t=-8.03, p=0.000), "technical terms"(t=6.65, p=0.000) pertain to this. 6. There were Significant differences in humor values concerning the time of using humor expression, "loose situation"(t=-3.75, p=0.000), "tired situation"(t=4.01, p=0.000), "tense situation"(t=5.37, p=0.000), "adequate situation"(t=-16.03, p=0.000) pertain to this.

• 한국진공학회지
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• 제4권2호
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• pp.119-123
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• 1995

Bridgman 방법으로 성장한 InSe: Co 단결정의 근적외 영역에서의 광흡수 특성을 상온에서 조사하였다. 1350, 1530, 1710nm 파장영역에서 Td 대칭을 갖는 Co2+ 이온의 4A2(4F)$\longrightarrow$4T1(4F)전이에 대응되는 3개의 흡수 peak를 관측하였다. 이 미세구조는 스핀-궤도 결합효과에 의하여 분리된 Co2+ 이온의 4T1(4F) 준위의 $\Gamma$6, $\Gamma$8, $\Gamma$7+$\Gamma$8 준위와 바닥상태 4A2(4F)의 $\Gamma$8 준위 사이의 전자전이에 기인하며, 결정장이론에 의하여 잘 설명되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권13호
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• pp.5261-5264
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• 2015

Purpose: To examine the effectiveness of serum free-to-total prostate specific antigen ratio (%fPSA) for the detection of prostate cancer (PCa) in men with different serum total PSA (tPSA) categories. Materials and Methods: From January 2010 to December 2013, a total of 225 patients with lower urinary tract symptoms (LUTS) underwent tPSA and %fPSA measurements. Histological examination with calculation of Gleason score and whole body bone scans were performed in identified cases of PCa. Results: PCa was diagnosed in 44 (19.6%) patients and the remaining 181 patients had benign prostate disease. PCa was detected in 5 (23.8%), 13 (8.7%) and 26 (47.3%) cases with tPSA level ranges ${\leq}4ng/ml$, 4 to 10 ng/ml and >10 ng/ml, respectively. The average Gleason score was $7.2{\pm}0.2$. Some 6 (13.6%) out of 44 PCa patients had bone metastases. The sensitivity was 80% and specificity was 81.3% at the cut-off %fPSA of 15% in PCa patients with a tPSA level below 4 ng/mL. A lower %fPSA was associated with PCa patients with Gleason score ${\geq}7$ than those with Gleason score ${\leq}6$ ($11.7{\pm}0.98$ vs. $16.5{\pm}2.25%$, P=0.029). No obvious relation of %fPSA to the incidence of bone metastasis was apparent in this study. Conclusions: The clinical application of %fPSA could help to discriminate PCa from benign prostate disease in men with a tPSA concentration below 4 ng/mL.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3569-3573
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• 2016

Purpose: The aim of this study was to compare C-11 choline and F-18 FDG PET/CT, gadoxetic-enhanced 3-T MRI and contrast-enhanced CT for diagnosis of hepatocellular carcinoma (HCC). Materials and Methods: Twelve chronic hepatitis B patients suspected of having HCC by abdominal ultrasonography received all diagnostic modalities performed within a one-week timeslot. PET/CT results were analyzed visually by two independent nuclear medicine physicians and quantitatively by tumor to background ratio (T/B). Nine patients then had histopathological confirmation. Results: Six patients had well differentiated HCC, while two and one patient(s) were noted with moderately and poorly differentiated HCC, respectively. All were detected by both CT and MRI with an average tumor size of $5.7{\pm}3.8cm$. Five patients had positive C-11 choline and F-18 FDG uptake. Of the remaining four patients, three with well differentiated HCC showed negative F-FDG uptake (one of which showed negative results by both tracers) and one patient with moderately differentiated HCC demonstrated no C-11 choline uptake despite intense F-18 FDG avidity. The overall HCC detection rates with C-11 choline and F-18 FDG were 78% and 67%, respectively, while the sensitivity of F-18 FDG for non-well differentiated HCC was 100%, compared with 83% of C-11 choline. The average T/B of C-11 choline in well-differentiated HCC patients was higher than in moderately and poorly differentiated cases (p=0.5) and vice versa with statistical significance for T/B of F-18 FDG (p = 0.02). Conclusions: Our results suggested better detection rate in C-11 choline for well differentiated HCC than F-18 FDG PET. However, the overall detection rate of PET/CT with both tracers could not compare with contrast-enhanced CT and MRI.

• 대한전기학회논문지
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• 제41권5호
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• pp.525-532
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• 1992

Fluorine-doped YBaS12TCuS13TOS17-xTFS1yT superconducting materials with y varing two orders of magnitude form 0.02 to 2.0 have been prepared by a sol-gel process by using metal nitrate salts, sodium hydroxide and sodium fluoride. Fluorine contents have been measured using an ion-selective electrode. All fluorine doped as reactant were found to be present in the resulted samples. From the observation of XRD it has been concluded that the samples with y 0.2 formed simply the single phase of perovskite structure, whereas those with y 0.5 yielded together some compounds such as BaFS12T, YFS13T and CuO in the resulted samples. The observation of solid state S019TF NMR has been carried out in order to check whether fluorine was actually incorporated into the lattice sites, and the experimental results revealed that the mole ratio of fluorine incorporated into the lattice sites of YBaS12TCuS13TOS17-xT was approximately 0.2 per mole of the compound. Also electrical resistivity measurement indicated that onset transition temperature has the tendency to increase slightly with increasing y in the dilute region as y 0.2.

• 한국보건간호학회지
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• 제26권2호
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• pp.227-238
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• 2012

Purpose: The purpose of this study was to examine physical activities and health belief in order to provide basic data on obesity prevention and management among elementary school students based on the health belief model. Methods: Participants included 194 fifth grade students in an elementary school located in Seoul. Data were collected by questionnaires and physical measurement, including weight and height. The SPSS Win 17.0 program using descriptive statistics, ANOVA with Scheff$\acute{e}$ post hoc tests, and Cronbach's alpha coefficients was used in data analysis. Results: Significant differences were observed in physical activity according to perceived severity (F=3.444, p=.034), perceived benefit (F=7.674, p=.001), perceived barrier (F=21.014, p<.001), and self-efficacy (F=22.098, p<.001). A significant difference in physical activity (t=4.502, p<.001) and perceived severity (t=-2.278, p=.024) was observed according to gender. Significant differences in physical activity (t=7.633, p=.006), perceived barrier (t=10.826, p=.001), and self-efficacy (t=5.928, p=.016) were observed according to obesity status. Significant differences were observed in physical activity (F=7.503, p=.001), perceived susceptibility (F=37.904, p<.001), and perceived barrier (F=3.425, p=.035) depending on level of satisfaction with body image. Conclusions: In order to promote physical activity among children with low physical activity, development of program with an emphasis on the benefits of physical activity and physical activity self-efficacy, and to decrease the barriers to physical activity is needed.

• 임상간호연구
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• 제21권1호
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• pp.67-79
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• 2015

Purpose: The study was aimed to describe the relationships between ego-resilience, disaster experience, and core competencies among emergency room (ER) nurses. Methods: Data were collected from ER nurses in Incheon and Kyunggi province from May to June 2014. Data were analyzed with descriptive study, t-test, ANOVA, and Pearson's correlation coefficient using SPSS/WIN 18.0 version. Results: Male respondents showed significantly higher ego-resilience than female respondents (t=-2.04, p=.043), and education (F=4.96, p=.002) and position (F=7.70, p=.001) were statistically significant. The differences in disaster experience was found in gender (t=-2.29, p=.023), age (F=4.25, p=.006), marital status (t=-2.02, p=.045), education (F=6.34, p<.001), religion (F=3.69, p=.015), and position (F=3.55, p=.031). Regarding core competencies for disaster nursing, age (F=7.80, p<.001), marital status (t=-3.00, p=.001), education (F=16.53, p<.001), career (F=5.40, p<.001), position (F=12.52, p<.001) were significantly different. Positive associations were found between core competencies for disaster nursing and ego-resilience (r=.66, p<.001), disaster experience and core competencies for disaster nursing (r=.52, p<.001), and disaster experience and ego-resilience (r=.33, p<.001). Conclusion: Core competencies were higher among ER nurses when they have higher ego-resilience, and more disaster experience. This finding suggests the need for improving ego-resilience among ER nurses. In addition, disaster education needs to be considered as a part of core nursing curriculum in college and clinical settings.