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In vivo Metabolism of Endosulfan in Carp (cyprinus carpio L.) (In vivo 시험에 의한 잉어(cyprinus carpio L.)체내 endosulfan의 대사)

  • Lee, K.B.;Shim, J.H.;Suh, Y.T.
    • Applied Biological Chemistry
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    • v.37 no.3
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    • pp.194-202
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    • 1994
  • To study the metabolism and absorption of endosulfan in carp, $^{14}C-{\alpha}-endosulfan$ was treated with the $LC_{10}$ concentration $(4.5\;{\mu}g/L)$. In an in vivo test, endosulfan was metabolized $(65{\sim}80%)$ in tissues and endosulfan ether, endosulfan alcohol, endosulfan ${\alpha}-hydroxyether$, and endosulfan lactone were identified, indicating that those are the main metabolites of detoxification in carp. The maximum levels of $^{14}C-endosulfan$ in the head, muscle, and gut occurred after 8 hr exposure. However, the maxima reached in the liver and kidneys after 30 min and 4 hr, respectively. Radioactivity in the tissue decreased rapidly 8 hr after treatment. The total amount of $^{14}C-endosulfan$ recovered in the liver, kidneys and gut of fish was about $80{\sim}90%$ during the 8 hr treatment. The non-extractable radioactivity increased after 8 hr exposure $(27{\sim}31%)$. Endosulfan sulfate, the main degradation product in plant and mouse, was not detected during the test interval from tissues of the carp.

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Smoking condition of students in dental hygiene and relations with self-esteem in a local district (일부지역 치위생과 학생들의 흡연 실태와 자아존중감과의 관계)

  • Lee, Sung-Lim;Go, Eun-Kyung;Choi, Jeong-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.12 no.1
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    • pp.123-133
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    • 2012
  • Objectives : This study was performed to understand smoking condition and to investigate the relations among knowledge regarding smoking and oral hygiene, awareness of anti-smoking policy, and self-esteem, to provide fundamental basis, developing programs for smoking prevention and anti-smoking. Methods : From September 7, 2010 to September 16, 2010, questionaire survey was conducted for 566 female university students studying dental hygienics at a local district in Jeollanam-do. Collected data was analyzed by Chi-square test, t-test, one way ANOVA, Scheffe multiple range test, Perason's correlation test, and stepwise multiple regression test. Results : 1. Smoking condition of study subjects on general characteristics showed 17.1%, where 14.0% of previous smoking history, and 68.9% of currently nonsmoker. 2. Analysis on the knowledge related to smoking and oral hygiene, awareness of anti-smoking policy, and self esteem on the general characteristics of study subjects have shown better awareness of anti-smoking policy in non-alcoholics. Significant difference was found in knowledge about smoking and awareness of anti-smoking policy according to current resident status, but no difference found in self-esteem. Higher academic grade was related to higher awareness of anti-smoking policy and better ics. aalcell. Better health, but no diffeoral hygiene were related to better awareness of anti-smoking policy, and bewhich were statistically significant. Favorable interpersonal self-estehip was related to better awareness of anti-smoking policy. 3. Analysis on knowledge regarding smoking related health and oral hygiene, awareness of anti-smoking policy, and self-esteem showed higher level of anti-smoking knowledge in non-smoking group(60.44) compared to currently smoking group or group with previous history of smoking, and better awareness of anti-smoking policy in non-smoking group(53.54) than other groups, which was statistically significant. 4. Correlation analysis among smoking related knowledge, awareness of anti-smoking policy, and self-esteem has found relatively high correlation between smoking related knowledge and awareness of anti-smoking policy, which was statistically significant(r=0.481, p<0.001). 5. Among factors influencing awareness of anti-smoking policy, higher level of smoking related knowledge and satisfaction to specialty was related to higher awareness of anti-smoking policy which was lower in current smoker than past smoker, and higher academic grade was related to higher awareness of anti-smoking policy. Conclusions : Following results emphasize the need to establish a novel curriculum by which effective programs for smoking prevention and education of anti-smoking specialist could be provided as well as promoting coaching anti-smoking activity.

The Relationship between Internet Addiction and School Life Adjustment in Elementary School Students (초등학생 아동들의 인터넷 중독과 학교생활 적응과의 관계)

  • Kim, Kyung-Bin;Lee, Moo-Sik;Na, Baeg-Ju;Hong, Jee-Young;Hwang, Ji-Hye
    • Proceedings of the KAIS Fall Conference
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    • 2010.05b
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    • pp.1205-1208
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    • 2010
  • 본 연구는 초등학교 5, 6학년 학생의 인터넷 중독과 학교생활 적응과의 관계를 파악하여 인터넷 사용에 대한 교육적 지도방안과 인터넷 중독 예방프로그램 개발의 기초 자료를 제공하고자 시도되었다. 자료는 2009년 7월 1일에서 7월 24일까지 제주특별자치도에 위치한 초등학교 6개교(동지역 4개교, 읍지역 2개교)를 무작위 추출하여 5, 6학년 학생 총 1195명을 대상으로 조사하였다. 자료 분석은 SPSSWIN(12.0 한글판) 프로그램을 이용하여 카이제곱검정, t-검정, 일원배치 분산분석, 상관분석, 다중회귀분석의 통계적 방법을 이용하였다. 본 연구의 주요 결과는 첫째, 대상자의 인터넷 중독 정도는 고위험군 55명(5.5%), 잠재적위험군 49명 (4.9%), 정상군 900명(89.6%)으로 나타났으며, 둘째, 대상자의 일반적 특성에 따른 인터넷 중독 정도를 분석한 결과 성별, 형제자매 유무, 학교성적에 따라 유의한 차이가 있었다. 셋째, 대상자의 컴퓨터 사용 특성에 따른 인터넷 중독 정도는 최초 인터넷 이용 시기, 인터넷 이용용도, 하루 인터넷 사용 시간, 부모컴퓨터 사용 여부에 따라 유의한 차이가 있었으며, 넷째, 인터넷 중독과 학교생활 적응과의 관계를 분석한 결과 학교생활 부적응인 경우는 '고위험군' 32명(58.2%), '잠재적위험군' 24명(50.0%), '정상군' 257명 (28.7%)으로 고위험군과 잠재적위험군이 정상군보다 학교생활 적응 정도가 낮은 것으로 조사되었다(p<0.01). 다섯째, 인터넷 중독에 유의한 영향을 주는 변수는 학교생활 적응 정도, 성별, 하루 인터넷 사용시간, 인터넷 이용용도, 인터넷 이용 상황, 어머니 직장 유무, 거주 지역, 부모 컴퓨터 사용여부, 최초 인터넷 이용시기이었다. 학교생활 적응 정도가 낮을 때, 남학생, 하루 인터넷 사용시간이 3시간 이상, 인터넷 이용 용도가 '게임', '스트레스가 쌓였을 때' 인터넷을 이용하는 경우, 어머니 직장이 있는 경우, 거주 지역이 동지역, 부모님이 컴퓨터를 사용할 줄 모르는 경우, 최초 인터넷 이용 시기가 취학 전인 경우가 인터넷 중독 점수가 높은 것으로 나타났다. 여섯째, 학교생활 적응에 유의한 영향을 주는 변수는 인터넷 중독 점수, 학교성적, 가정경제수준, 거주지역, 인터넷 이용용도, 학년이었다. 인터넷 중독 점수가 낮을수록, 학교성적이 높을수록, 가정경제수준이 잘 살수록, 거주지역이 동지역, 인터넷 이용용도가 '정보검색, 홈페이지관리/메신저', 5학년인 경우에 학교생활 적응을 더 잘하고 있는 것으로 나타났다. 이상의 결과를 종합해 보면, 학교생활 적응 정도가 낮을수록 인터넷 중독 점수가 높게 나타나고 있고, 인터넷 중독 경향이 높을수록 학교생활 적응 수준이 낮게 나타나고 있음을 알 수 있다. 아동들은 하루중 대부분의 시간을 학교에서 생활하고 있기 때문에 학교생활 적응은 아동들이 건전한 성인으로 성장하는데 중요한 요인이 된다. 또한, 인터넷사용률 증가와 최초 인터넷 이용 연령층이 점점 낮아지고 있음에 따라 인터넷 중독률이 자연스럽게 점점 높아질 것으로 예측되어진다. 따라서, 가정과 학교가 연계하여 아동들의 인터넷 사용에 대한 지속적인 관심과 지도가 필요하며, 인터넷 중독경향이 높은 아동들이 학교생활 적응을 잘할 수 있도록 인터넷 중독 치료 및 예방교육 프로그램 운영이 필요하다 하겠다.

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Gender Differences in Predictors of Health Behaviors Modification among Patients with Cardiovascular Disease (성별에 따른 심혈관질환자의 건강행위에 미치는 요인)

  • Xu, Lijuan;Ryu, Seungmi;Goong, Hwasoo
    • The Journal of the Korea Contents Association
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    • v.15 no.3
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    • pp.280-289
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    • 2015
  • Purpose: The purpose of the study was to investigate the difference of health behavior modification between male and female patients with cardiovascular disease; and to compare the predictors of health behavior between the male and female subjects. Methods: A comparative study design was used in the study. A total of 228 patients(male 114, female 114) with cardiovascular disease were recruited from outpatients clinics in 2 university hospitals in Korea. Data were analyzed using t-test, $X^2$, ANOVA, ANCOVA, Pearson correlation, and multiple regression with SPSS 20.0. Results: There was significant difference of health behavior between male and female patients with cardiovascular disease (F=9.45, p=0.002). The significant predictors of health behavior among male subjects were self-efficacy, perceived barriers, perceived susceptibility, medical support and autonomous motivation, accounting for 45%; the significant predictors of health behavior among female subjects were self-efficacy, medical support and autonomous motivation, accounting for 51%. Conclusions: It is suggested to take different health promotions strategies to maintain the performance of health behaviors among male and female patients with cardiovascular diseases.

Middle School Students' Interest and Practice of Housing Education Contents Based on Jeonbuk Province (중학생의 주생활 교육내용에 대한 관심도와 활용도 조사 연구 -전북지역을 중심으로-)

  • Jin Sang Youn;Kwark Kyoung Sook
    • Journal of Korean Home Economics Education Association
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    • v.16 no.4 s.34
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    • pp.81-94
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    • 2004
  • The purpose of this study was to research middle school students' interest and practice about the housing education contents in Technology and Home Economics Subject(classify them into three units, application of living space, indoor environment and equipments. support and repair of housing) in their real life. This was the investigation of which 529 middle school students have lived in Jeonbuk province, SPSS program was utilized to analyze percentage. mean and standard deviation. as well as t-test, One-Way ANOVA and Pearson's correlation coefficients. The results of this research were as follows: Middle school students' interest and practice of the housing education contents appeared to the middle level. Middle school students was consider that the order of interest parts of housing contents were indoor environment and equipments. application of living space, support and repair of housing. And the order of practice parts of housing contents were application of living space. indoor environment and equipments. support and repair of housing. There were significant differences in interest and practice of contents according to demographic variables such as sex, educational level of parents, social status of home. school record. Interest about the housing education contents had significant positive relationships with practices of contents of housing education. Therefore. it would be necessary to develop teaching materials and housing education contents promoting interest of students.

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Electrochemical Properties of Zr0.8Ti0.2Mn0.4V0.6Ni1-xFex Alloy Electrodes (Zr0.8Ti0.2Mn0.4V0.6Ni1-xFex 합금 전극의 전기화학적 특성)

  • Song, MyoungYoup;Kwon, IkHyun;Lee, DongSub
    • Transactions of the Korean hydrogen and new energy society
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    • v.13 no.3
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    • pp.181-189
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    • 2002
  • A series of multicomponent $Zr_{0.8}Ti_{0.2}Mn_{0.4}V_{0.6}Ni_{1-x}Fe_{x}$ (x=0.00, 0.08, 0.15, 0.22, and 0.30) alloys are prepared and their oystal structure and P-C-T curves are examined. The electrochemical properties of these allqys such as activation conditions, discharge capacity, cycling performance are also investigated. $Zr_{0.8}Ti_{0.2}Mn_{0.4}V_{0.6}Ni_{1-x}Fe_{x}$ (x=0.00, 0.08, 0.15, 0.22 and 0.30) have the C14 Laves phase hexagonal structure. The electrode was activated by the hot-charging treatment. The best activation conditions were the current density 120 mA/g and the hot-charging time 12h at $80^{\circ}C$ in the case of the alloy with x=0.00. The discharge capacity increased rapidly until the fourth cycle and then decreased. The discharge capacity increased again from the 13th cycle, arriving at 234 mAh/g at the 50th cycle. The discharge capacily just after activation decreases with the increase in the amount of the substituted Fe but the cycling performance is improved. The discharge capacity after activation of the alloy with x=0.00 is 157 mAh/g at the current density 120 mA/g. $Zr_{0.8}Ti_{0.2}Mn_{0.4}V_{0.6}Ni_{0.85}Fe_{0.15}$ is a good composition with a medium quantity of discharge capacities and a good cycling performance. The ICP analysis of the electrolyte for these electrodes after 50 charge-discharge cycles shows that the concentrations of V and Zr are relatively high. Another series of multicomponent $Zr_{0.8}Ti_{0.2}Mn_{0.4}V_{0.6}Ni_{0.85}M_{0.15}$ (M = Fe, Co, Cu, Mo and Al) alloys are prepared. They also have the C14 Laves phase hexagonal structure. The alloys with M = Co and Fe have relatively larger hydrogen storage capacities. The discharge capacities just after activation are relatively large in the case of the alloys with M = Al and Cu. They are 212 and 170 mAh/g, respectivety, at the current density 120mA/g. The $Zr_{0.8}Ti_{0.2}Mn_{0.4}V_{0.6}Ni_{0.85}Co_{0.15}$ alloy is the best one with a relatively large discharge capacity and a good cycling performance.

THE EFFECT OF DIFFERENTIAL MODULATION OF N-METHYL-D-ASPARTATE RECEPTOR ON THE PROLIFERATION OF PRIMARY CULTURED NORMAL HUMAN ORAL KERATINOCYTES: DNA SYNTHESIS RATE ANALYSIS (N-methyl-D-aspartate 수용기의 다양한 조절이 일차 배양된 정상사람구강각화세포의 증식에 미치는 영향; DNA 합성율 평가)

  • Kim, In-Soo;Paik, Ki-Suk;Chang, Mi-Sook;Lee, Won;Lee, Seung-Pyo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.2
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    • pp.124-130
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    • 2007
  • In the present study, I investigated the effects of N-methyl-D-aspartate (NMDA), arachidonic acid (AA), and Nitric Oxide Synthase Inhibitor (NOSI), alone or in combination, on the proliferation of cultured primary normal human oral keratinocytes (NHOK). The purpose of this study was therefore the preliminary study for the examination of the interaction between these agents and NHOK in order to elucidate the mechanisms by which epithelial growth and regeneration are regulated. NHOK were obtained from gingival tissue of 20 individuals aged 20 to 29, and third passage (P3) cells were used for this study. The DNA synthesis was measured by the BrdU assay. Addition of low concentration of AA ($1{\mu}M$) and high concentration of AA with NMDA group (NMDA+AA $10{\mu}M$) made DNA synthesis rate increase significantly at the early stage. Adding NNA ($10{\mu}M$) affected DNA synthesis rate to increase significantly in 4 hours. At the early stage, DNA synthesis was significantly active in the NOS-I with NMDA groups than in the control and the NMDA-only group, while it didn't become statistically meaningful in 24 hours. AA $1{\mu}M$ and NNA $10{\mu}M$ may induce the proliferation of the NHOK independently and NOS-I may induce the proliferation of the NHOK with NMDA. These reactions might be related to the NMDA receptor in the cell and the change of the intracellular calcium ion concentration.

The effects of bioactive glass on the periodontal healing of 1-wall intrabony defects in dogs (성견 1면 골결손부에서 Bioactive Glass가 치주조직 치유에 미치는 영향)

  • Park, Weon-Yeong;Cho, Kyoo-Sung;Chai, Jung-Kiu;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
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    • v.28 no.1
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    • pp.145-160
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    • 1998
  • The ultimate goal of periodontal therapy is the regeneration of periodontal tissue which has been lost due to destructive periodontal disease, and numerous kinds of materials and techniques have been developed to achieve this goal. Bone grafts include autografts, allografts, xenografts and synthetic grafts. Among the synthetic grafts, bioactive glass has been used in dentistry for more than ten years and Fetner reported improved new bone formation and more amount of new attachment after grafting PerioGlas, a kind of bioactive glass, in 2-wall defects of monkeys in 1994. It Is well known that 1-wall defects have less osteogenic potential and more epithelial migration, so we need to study the erect of bioactive glass in 1-wall dejects in dogs. The present study evaluates the effect of bioactive glass on the epithelial migration, alveolar bone regeneration, cementum formation and gingival connective tissue attachment in intrabony detects of dogs. Four millimeter deep and four millimeter wide 1-wall defects were surgically cheated in the mesial aspects of premolars. The test group received bioactive glass with a flap procedure and the control underwent flap procedure only. Histologic analysis after 8 weeks of healing revealed the following results: 1. The height of gingival margin was 1.30{\pm}0.73mm$ above CEJ in the control and $1.40{\pm}0.78mm$ in the test group. There was no statistically significant difference between the two group. 2. The length of epithelial growth (the distance from CEJ to the apical end of JE) was $1.74{\pm}0.47mm$ in the control and $1.12{\pm}0.36mm$ in the test group. These was a statistically significant difference between the two groups (P<0.01). 3. The length of new cementum was $2.06{\pm}0.73mm$ in the control and $2.62{\pm}0.37mm$ in the test group. There was no statistically significant difference between the two groups. 4. The length of new bone was $1.83{\pm}0.74mm$ in the control and $2.39{\pm}0.59mm$ in the test group. There was no statistically significant difference between the two groups. These results suggest that the use of bioactive glass 1-wall intrabony defects has significant effect on the prevention of junctional epithelium migration, but doesn't have any significant effect on new bone and new cementum formation.

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Current Status of Pediatric Surgical Practice in Korea -a Survey among the Members of Korean Association of Pediatric Surgeons- (대한소아외과학회 회원의 1995년도 진료현황 및 수련경력 설문조사)

  • Kim, W.K.;Kim, S.Y.;Kim, S.K.;Kim, I.K.;Kim, J.E.;Kim, C.S.;Kim, H.H.;Park, K.W.;Park, Y.S.;Park, W.H.;Park, J.S.;Song, Y.T.;Yang, J.W.;Oh, S.M.;Lee, D.S.;Lee, M.D.;Lee, S.K.;Lee, S.C.;Chang, S.I.;Jung, S.E.;Jung, P.M.;Choi, K.J.;Choi, S.O.;Huh, Y.S.;Hwang, E.H.
    • Advances in pediatric surgery
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    • v.3 no.1
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    • pp.61-67
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    • 1997
  • To understand the current status of pediatric surgical practice of the members of the Korean Association of Pediatric Surgeons, a survey of the practice of the 31 members in both 1994 and 1995. Twenty five members(80%) representing 20 hospitals responded. An average of four hundred and seventy four cases pediatric surgical operations were performed at individual institution in 1995 with 40 newborn cases. Eighteen members(72%) are currently working at university hospital. Fourteen institutions(70%) are currently classified as tertiary by the health insurance agency. The majority(15 to 60%) of members are working in the metropolitan Seoul area, while five in Taegu area. Sixteen members reported having the title of department head/director. Four members reported occasional non-pediatric surgical practice. Nine members out of 20 reported having independent pediatric surgical out-patient clinic before the establishment of the association(1985). Eight out of 15 members reported being appointed chief of pediatric surgery before 1985. In 20 institutions, 34 full time physicians(27 members, reportedly) are working in pediatric surgery. In regarding to pediatric surgical training, 16 members(64%) received an average of 16 months of training abroad, 5 members trained at home and abroad, and 4 from only at home. There are no differences in length of training periods in these groups. Twenty one members received their basic pediatric surgical training before 1985, the year of inauguration of the association. Twelve members received post-pediatric surgery refresher courses averaging 11 months' duration, after 2-11 years. Thirteen participants of this study belongs to the founding members of the association.

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The Effects of Wearing Roller Shoes on Ground Reaction Force Characteristics During Walking (롤러 신발과 조깅 슈즈 신발 착용 후 보행 시 지면반력의 형태 비교 분석)

  • Chae, Woen-Sik
    • Korean Journal of Applied Biomechanics
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    • v.16 no.1
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    • pp.101-108
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    • 2006
  • The purpose of this study was to compare GRF characteristics during walking wearing jogging and roller shoes. Twelve male middle school students (age: $15.0{\pm}0.0\;yrs$, height: $173.6{\pm}5.0\;cm$, weight: $587.6{\pm}89.3\;N$) who have no known musculoskeletal disorders were recruited as the subjects. Kinematic data from six S-VHS camcorders(Panasonic AG456, 60 fields/s) and GRF data from two force platform; (AMII OR6-5) were collected while subjects walked wearing roller and jogging shoes in random order at a speed of 1.1 m/s. An event sync unit with a bright LED light was used to synchronize the video and GRF recordings. GRF data were filtered using a 20 Hz low pass Butterworth. digital filter and further normalized to the subject's body weight. For each trial being analyzed, five critical instants and four phases were identified from the recording. Temporal parameters, GRFs, displacement of center of pressure (DCP), and loading and decay rates were determined for each trial. For each dependent variable, paired t-test was performed to test if significant difference existed between shoe conditions (p <.05). Vertical GRFs at heel contact increased and braking forces at the end of initial double limb stance reduced significantly when going from jogging shoe to roller shoe condition. Robbins and Waked (1997) reported that balance and vertical GRF are closely related It seems that the ankle and knee joints are locked in an awkward fashion at the heel contact to compensate for the imbalance. The DCP in the antero-posterior direction for the roller shoe condition was significantly less than the corresponding value for the jogging shoe condition. Because the subjects tried to keep their upper body weight in front of the hip to prevent falling backward, the DCP for the roller shoe condition was restricted The results indicate that walking with roller shoes had little effect on temporal parameters, and loading and decay rates. It seems that there are differences in GRF characteristics between roller shoe and jogging shoe conditions. The differences in GRF pattern may be caused primarily by the altered position of ankle, knee, and center of mass throughout the walking cycle. Future studies should examine muscle activation patterns and joint kinematics during walking with roller shoes.