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The clinical study of Digital Infrared Thermographic Imaging on Depressed patients (전신체열촬영(全身體熱撮影)에 의한 우울증(憂鬱症)과 안면마비(顔面麻痺)의 객관적(客觀的) 진단방법(診斷方法) 모색(摸索))

  • Kim Tae-Heon;Lee Yong-Keun;Lyu Yeong-Su
    • Journal of Oriental Neuropsychiatry
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    • v.11 no.2
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    • pp.87-102
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    • 2000
  • Depression is a psychiatric syndrom consisting of dejected mood, psychomotor retardation, insomnia and weight loss. sometimes associated with irrational quilt feeling. And it is also similiar to Hwa-byung(火病) symptom in oriental medicine. But it is difficult to diagnose with objective method. Digital Infrared Thermographic Imaging(D.I.T.I.) is one of diagnotic method that measure the changes of skin temperature in body.Specially we checked the skin temperature on depressed patients by using D.I.T.I. and compared with Bell's palsy patients and normal persons group.The results are as follows:Average body temperature of the depressed patient group is 36.62${\cdot}$0.58$^{\circ}C$ , Bell's palsy patients group is 36.59${\cdot}$0.34$^{\circ}C$ and that of the control group is 36.71${\cdot}$0.43$^{\circ}C$ . So there is no meaningful difference. The depressed patient group has higher temperature than the Bell's palsy patients group and control group by $\delta$T〉1.0$^{\circ}C$ at the following acupuncture points in these body parts - upper and lower, left and right, anterior and posterior. When acupuncture points temperature was compared superior and inferior part of the body, depressed patient group have meaningful difference at the GV-4 (Myung-moon) and also in the Bell's palsy patients group and control group.When acupuncture points temperature was compared left and right part of the body. ddpressed patient group have no meaningful difference and also in the Bell's palsy patients group and control group.When acupuncture points temperature was compared in the anterior and posterior part of the body, depressed patient group have meaningful difference at the Gv-4(Myung-moon) and also in the bell's palsy patients group and control group.From this study. we think that D.I.T.I. could be used to diagnose objectively on the depressed patients and useful to another psychoneurogenic diagnosis in oriental medicine.

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A Study on the Effect of the Urban Regeneration Project on the Reduction of Carbon Emission - A Case Study of Jeonju Test-Bed - (도시재생사업 적용에 따른 탄소저감 효과 - 전주TB지역을 대상으로 -)

  • Park, Kiyong;Lee, Sangeun;Park, Heekyung
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.65-74
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    • 2016
  • This study mainly focuses on urban regeneration project as a countermeasure to resolve climate change issues by analyzing the carbon-reduction effect of Jeonju test-bed cases. First, an urban regeneration project is designed for city, Jeonju by analyzing its environmental problems and potential improvement. Then, carbon emission and reduction amounts are evaluated for different businesses and scenarios. Carbon emission sources are classified according to a standard suggested by IPCC, and the emissions are calculated by various standard methods. The result shows that carbon emission amount in Jeonju test-bed is 102,149 tCO2eq. The fact that 70% of the emission from energy sector originates from buildings implies that urban regeneration projects can concentrate on building portions to effectively reduce carbon emission. It is also projected carbon emission will decrease by 3,826tCo2eq in 2020 compared to 2011, reduction mainly based on overall population and industry shrinkage. When urban regeneration projects are applied to 5 urban sectors (urban environment, land use, green transportation, low carbon energy, and green buildings) total of 10,628tCO2eq is reduced and 4,857tCO2 (=15.47%) when only applied to the green building sector. Moreover, different carbon reduction scenarios are set up to meet each goal of different sectors. The result shows that scenario A, B, and C each has 5%, 11%, and 15% of carbon reduction, respectively. It is recommended to apply scenario B to achieve 11% reduction goal in a long term. Therefore, this research can be a valuable guideline for planning future urban regeneration projects and relative policies by analyzing the present urban issues and suggesting improvement directions.

Bioequivalence and Pharmacokinetics of 70 mg Alendronate Sodium Tablets by Measuring Alendronate in Plasma

  • Yun Min-Hyuk;Woo Jong-Su;Kwon Kwang-Il
    • Archives of Pharmacal Research
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    • v.29 no.4
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    • pp.328-332
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    • 2006
  • The bioequivalence and pharmacokinetics of alendronate sodium tablets were examined by determining the plasma concentration of alendronate. Two groups, consisting of 24 healthy volunteers, each received a 70 mg reference alendronate sodium tablet and a test tablet in a $2{\times}2$ crossover study. There was a 6-day washout period between doses. The plasma alendronate concentration was monitored for 7 h after the dose, using HPLC-Fluorescence Detector (FD). The area under the plasma concentration-time curve from time 0 to the last sampling time at 7 h $(AUC_{0-7h})$ was calculated using the linear-log trapezoidal rule. The maximum plasma drug concentration $(C_{max})$ and the time to reach $C_{max}(T_{max})$ were derived from the plasma concentration-time data. Analysis of variance was performed using logarithmically transformed $AUC_{0-7h}\;and\;C_{max}$, and untransformed $T_{max}$. For the test medication versus the reference medication, the $AUC_{0-7h}\;were\;87.63{\pm}29.27\;vs.\;102.44{\pm}69.96ng\;h\;mL^{-1}$ and the $C_{max}$ values were $34.29{\pm}13.77\;vs.\;38.47{\pm}24.39ng\;mL^{-1}$ respectively. The $90\%$ confidence intervals of the mean differences of the logarithmic transformed $AUC_{0-7h}$ and $C_{max}$ values were log 0.8234-log 1.1597 and log 0.8222-log 1.1409, respectively, satisfying the bioequivalence criteria guidelines of both the US Food and Drug Administration and the Korea Food and Drug Administration. The other pharmacokinetic parameters for the test drug versus reference drug, respectively, were: $t_{1/2},\;1.87{\pm}0.62\;vs.\;1.77{\pm}0.54\;h;\;V/F,\;2061.30{\pm}986.49\;vs.\;2576.45{\pm}1826.05\;L;\;CL/F,\;835.32{\pm}357.35\;vs.\;889.48{\pm}485.87\;L\;h^{-1}; K_{el},\;0.42{\pm}0.14\;vs.\;0.40{\pm}0.18\;h^{-1};\;Ka,\;4.46{\pm}3.63\;vs.\;3.80{\pm}3.64\;h^{-1};\;and\;T_{lag},\;0.19{\pm}0.09\;vs.\;0.18{\pm}0.06\;h$. These results indicated that two alendronate formulations(70-mg alendronate sodium) were biologically equivalent and can be prescribed interchangeably.

A study on the Detection of Artificial Dyes in the Commercial Jellys by Use of Paper Chromatography and Thin-Layer Chromatography. (Paper chromatography와 Thin-layer chromatography에 의한 시판 Jelly류의 착색료에 관한 고찰)

  • 구성회;오석흔;우세홍;한양일;이성호;남궁석;박선이
    • Journal of Environmental Health Sciences
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    • v.4 no.1
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    • pp.10-12
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    • 1977
  • A study was carried out to detect of illegal artificial dyes and to confirm the used rate of illegal dyes in the production process of commercial jellys by thindayer chromatography and paper chromatography, from March, 1976 to July, 1976. The following conclusions were obtained 1. Seperated dyes were amaranth, erythrosin, tatrazin, sunset yellow FCF, fight green SF yellowish, fast green FCF and the most frequent use of amaranth. 2. Used rate of legal dyes were 94.12% (96 samples) and illegal dyes were 5.88% (6 samples) with samples 102. 3. The average Rf value of T.L.C. were amaranth (0.92), erythrosin (0.48), tatrazin (0.83), sunset yellow FCF(0.86), fast green FCF (0.63), light green SF yellowish (0.23) and paper chromatography were amaranth (0.76), erythrosin (0.44), tatrazin(0.75), sunset yellow FCF (0.76), fast green FCF (0.86), light green SF yellowish(0.52).

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Purification and Charactedrization of Cysteine Desulfhydrase from Streptomyces albidoflavus SMF301

  • Ryu, Jae-Gon;Kang, Sung-Gyun;Kim, In-Seop;Rho, Young-Taik;Lee, Sang-Hee;Lee, Kye-Joon
    • Journal of Microbiology
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    • v.35 no.2
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    • pp.97-102
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    • 1997
  • Cysteine desulfhydrase (EC 4.4.1.1.) was purified from the culture supernatant of Streptomyces albidoflavus SMF301 by hydroxyapatite, gel filtration and Resource Q ion-exchange chromatography with a purification fold of six identical subunits. The enzyme was stabilized by dithiothreitol and pyridoxal 5'-phosphate during the purification procedures. The optimum pH and temperature were pH 8.6 and 35$^{\circ}C$, respectively. The N-terminal amino acid sequence was identified as A-P-L-P-T-A-D-V-R-S-D-P-G-Y-R-E-W-L-G-E-A-V. The purified cystein desulfhydrase had a high substrate specificity toward cysteine, and exhibited no cystahionine $\gamma$-lyase activity. The $K_m$ value for cysteine was determined to be 0.37 mM.

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Properties of Heat-transfer on Lightweight Concrete Using Bottom ash (Bottom ash를 이용한 기포콘크리트의 열전도 특성)

  • 이승한;이중우;공성훈;정해구
    • Proceedings of the Korea Concrete Institute Conference
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    • 1995.10a
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    • pp.93-102
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    • 1995
  • In this study the characteristics of adiabatic and lightweight of cement mortar was improved by using porous Bottom ash which was industrial waste. when a foaming agent was added, the characteristics of mortar using sand and Bottom ash were compared. From the empirical results the heat-transfer ratio for the mortar using Bottom ash only was shown the lower values than that for a general mortar, and the lightweight concrete with unit weight of 1.5t/$\textrm{m}^3$ could be made. When the foaming agent of 0.25% and 0.5% in usage of cement was added to that, the compressive strength scould be measured as 5 and 8times of the general mortar respectively. Also, the characteristics of adiabatic for that mortar was great improved so that the heat-transfer ratio was fallen to 0.172kcal/$mh^{\circ}C$.

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Evaluation of Aluminum Part by Rheo Die Casting (레오다이캐스팅에 의한 알루미늄 부품의 평가)

  • Seo P. K.;Jung Y. S.;Kang C. G.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2004.10a
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    • pp.99-102
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    • 2004
  • In rheo forming process, slurry making is very important factor because the microstructure of slurry affects the quality of final products. To control the microstructure of slurry, slurry making by new rheo die casting was studied. In new rheocasting method, processes parameters are degree of overheat in molten metal, cooling condition, high frequency induction heating condition and cup temperature. Microstructures according to these parameters were observed. By image analysis, equivalent diameter and roundness of grain were investigated and discussed. To find out mechanical properties of grain controlled aluminum part by rheo die casting, tensile tests were carried out to the T6 heat treatment.

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Synthesis, X-Ray Crystal Structure and Coupling Reactions of 4,5-($1^{\prime},2^{\prime}$-diphenylethylenedithio)-1,3-dithiole-2-thione (dPhEDT-DTT)

  • 이하진;노동윤
    • Bulletin of the Korean Chemical Society
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    • v.19 no.3
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    • pp.340-344
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    • 1998
  • A facile synthesis of 4,5-(1',2'-diphenylethylenedithio)-1,3-dithiole-2-thione (dPhEDT-DTT) is carried out via a Diels-Alder type [2+4] cycloaddition reaction of 1,3-dithiol-2,4,5-trithione oligomer and t-stilbene. Molecular structure of dPhEDT-DTT is determined by x-ray crystallography: space group P1, a=11.694(3) Å, b=12.117(3) Å, c=14.688(3) Å, α=113.12(2)°, β=102.23(2)°, γ=107.02(2)°, V= 1699.1(7) Å3, Z=2. It turns out that dPhEDT-DTT crystallizes as a racemic compound consisting of (R,R) and (S,S) enantiomers. Coupling reaction of dPhEDT-DTO undergone in neat P(OEt)3 yields TTF(SEt)4 instead of ET derivative. When PR3 (R=OEt, OPh, Ph) is used in benzene, toluene or xylene, however, dPhEDT-DTO is decomposed.