• Nutrition Research and Practice
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• v.15 no.5
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• pp.541-554
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• 2021

BACKGROUND/OBJECTIVES: Isoflavones (ISFs) are effective in preventing bone loss, but not effective enough to prevent osteoporosis. Mixtures of soy ISF and lecithin (LCT) were prepared and characterized in an attempt to improve the bone loss. MATERIALS/METHODS: The daidzein (DZ) and genistein (GN) solubility in soy ISF were measured using liquid chromatography-mass spectrometry. The change in the crystalline characteristics of soy ISF in LCT was evaluated using X-ray diffraction analysis. Pharmacokinetic studies were conducted to evaluate and compare ISF bioavailability. Animal studies with ovariectomized (OVX) mice were carried out to estimate the effects on bone loss. The Student's t-test was used to evaluate statistical significance. RESULTS: The solubility of DZ and GN in LCT was 125.6 and 9.7 mg/L, respectively, which were approximately 25 and 7 times higher, respectively, than those in water. The bioavailability determined by the area under the curve of DZ for the oral administration (400 mg/kg) of soy ISF alone and the soy ISF-LCT mixture was 13.19 and 16.09 ㎍·h/mL, respectively. The bone mineral density of OVX mice given soy ISF-LCT mixtures at ISF doses of 60 and 100 mg/kg daily was 0.189 ± 0.020 and 0.194 ± 0.010 g/mm³, respectively, whereas that of mice given 100 mg/kg soy ISF was 0.172 ± 0.028 g/mm³. The number of osteoclasts per bone perimeter was reduced by the simultaneous administration of soy ISF and LCT. CONCLUSIONS: The effect of preventing bone loss and osteoclast formation by ingesting soy ISF and LCT at the same time was superior to soy ISF alone as the bioavailability of ISF may have been improved by the emulsification and solvation of LCT. These results suggest the possibility of using the combination of soy ISF and LCT to prevent osteoporosis.

• Journal of The Korean Astronomical Society
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• v.54 no.4
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• pp.129-137
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• 2021

It has been established that the acoustic mode parameters of the Sun and Sun-like stars vary over activity cycles. Since the observed variations are not consistent with an activity-related origin, even Sun-like stars showing out-of-phase changes of mode frequencies and amplitudes need to be carefully studied using other observational quantities. In order to test whether the presumed relations between the global seismic parameters are a signature of the stellar activity cycle, we analyze the photometric light curve of HD 49933 for which the first direct detection of an asteroseismic signature for activity-induced variations in a Sun-like star was made, using observations by the CoRoT space telescope. We find that the amplitude of the envelope significantly anti-correlates with both the maximum frequency of the envelope and the width of the envelope unless superflare-like events completely contaminate the light curve. However, even though the photometric proxy for stellar magnetic activity appears to show relations with the global asteroseismic parameters, they are statistically insignificant. Therefore, we conclude that the global asteroseismic parameters can be utilized in cross-checking asteroseismic detections of activity-related variations in Sun-like stars, and that it is probably less secure and effective to construct a photometric magnetic activity proxy to indirectly correlate the global asteroseismic parameters. Finally, we seismically estimate the mass of HD 49933 based on our determination of the large separation of HD 49933 with evolutionary tracks computed by the MESA code and find a value of about 1.2M_☉ and a sub-solar metallicity of Z = 0.008, which agrees with the current consensus and with asteroseismic and non-asteroseismic data.

• Journal of muscle and joint health
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• v.28 no.2
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• pp.152-160
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• 2021

Purpose: This study, using the International Classification for Nursing Practice, aimed to identify the phenomenon of family nursing care, and the factors affecting it, for high-risk and frail older persons who have a significant need for home healthcare services. Methods: This study was conducted using secondary data collected by students who interviewed 93 healthcare subjects in a health center. The data was used to analyze the general characteristics, health-related characteristics, and confirmed problems of family nursing phenomena of the subjects. Independant t-test, Pearson correlation coefficient, and multiple linear regression were used for the data analysis. Results: The mean age of the subjects was 82.4±6.3 years. The most common problem of the family nursing phenomenon were unhealthy lifestyle, disturbance in family communication, and lack of family interaction in the community. People with greater family nursing phenomenon problems reported a higher degree of frailty and depression, lower quality of life and self-rated health. The factors that influence the family nursing phenomenon of frail older persons are the problems of mobility and hearing. Conclusion: Physical and psychological problems associated with aging can cause not only personal, but family functional problems as well. Therefore, a comprehensive family-oriented support program is required.

• Animal Bioscience
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• v.34 no.10
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• pp.1684-1694
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• 2021

Objective: This study investigated the association between feed efficiency, physicochemical properties, flavor precursors and biomolecules in the thigh meat of Korat (KR) chickens. Methods: The feed intake and body weight of individual male KR chickens were recorded from 1 to 10 weeks old to calculate the individual residual feed intake (RFI) of 75 birds. At 10 weeks of age, chickens with the 10 highest (HRFI) and lowest RFI (LRFI) were slaughtered to provide thigh meat samples. The physicochemical properties (ultimate pH, water holding capacity [WHC], drip loss) and flavor precursors (guanosine monophosphate, inosine monophosphate (IMP), adenosine monophosphate and inosine) were analyzed conventionally, and Fourier transform infrared spectroscopy was used to identify the composition of biomolecules (lipids, ester lipids, amide I, amide II, amide III, and carbohydrates) and the secondary structure of the proteins. A group t-test was used to determine significant differences between mean values and principal component analysis to classify thigh meat samples into LRFI and HRFI KR chickens. Results: The physicochemical properties of thigh meat samples from LRFI and HRFI KR chickens were not significantly different but the IMP content, ratios of lipid, lipid ester, protein (amide I, amide II) were significantly different (p<0.05). The correlation loading results showed that the LRFI group was correlated with high ratios of lipids, lipid esters, collagen content (amide III) and beta sheet protein (rg loading >0.5) while the HRFI group was positively correlated with protein (amide I, amide II), alpha helix protein, IMP content, carbohydrate, ultimate pH and WHC (rg loading >0.5). Conclusion: The thigh meat from chickens with different RFI differed in physiochemical properties affecting meat texture, and in the contents of flavor precursors and biomolecules affecting the nutritional value of meat. This information can help animal breeders to make genetic improvements by taking more account of traits related to RFI.

• The Journal of Economics, Marketing and Management
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• v.9 no.5
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• pp.39-50
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• 2021

Purpose: This study is to analyze the changes of consumption patterns to diagnose the economic impacts on consumers' market during COVID-19, and to suggest implications to overcome the new social and economic crisis of Jeju Island. Research design, data, and methodology: We collected a set of credit card transaction records issued by BC Card Company from merchants in Jeju Special Self-Governing Province for past 4 years from 2017 to 2020 from the Jeju Data Hub run by Jeju Special Self-Governing Province. The big data contains details of approved credit card transactions including the approval numbers, amount, locations and types of merchants, time and age of users, etc. The researchers summed up amount in monthly basis, transforming big data to small data to analyze the changes of consumption before and after COVID-19. Results: Sales fell sharply in transportation industries including airlines, and overall consumption by age group decreased while the decrease in consumption among the seniors was relatively small. The sales of Yeon-dong and Yongdam-dong in Jeju City also fell significantly compared to other regions. As a result of the paired t-test of all 73 samples in Jeju City, the p-value of the mean consumption of the credit card in 2019 and 2020 is significant, statistically proven that the total consumption amount in the two years is different. Conclusions: We found there are sensitive spots that can be strategically approached based on the changes in consumption patterns by industry, region, and age although most of companies and small businesses have been hit by COVID-19. It is necessary for local companies and for the government to be focusing their support on upgrading services, in order to prevent declining sales and job instability for their employees, creating strategies to retain jobs and prevent customer churn in the face of the crisis. As Jeju Province is highly dependent on the tertiary industry, including tourism, it is suggested to create various strategies to overcome the crisis of the pandemic by constantly monitoring the sales trends of local companies.

• Journal of Korean society of Dental Hygiene
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• v.21 no.2
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• pp.151-158
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• 2021

Objectives: The purpose of this study was to identify the effects of general and oral health status on dementia. Methods: Questionnaires were used for the KDSQ-C (Korean Dementia Screening Questionnaires-Cognition) and to investigate the oral health status of the participants. An independent t-test was conducted to analyze the differences between general health and oral health status depending on the normal and suspected dementia groups. Logistic regression analysis was performed to assess the effects of general and oral health status on dementia. Results: Regarding the health status of the subjects assessed by the KDSQ-C, the higher the current health status and the higher the exercise status, the lower was the dementia level (p<0.05). During the assessment of oral health conditions in KDSQ-C subjects, dementia was more suspected in subjects with dental decay and periodontal disease than in those without dental decay (p<0.05). Conclusions: Dementia has been confirmed to be closely related to general and oral health conditions. Therefore, oral health-related programs are essential for dementia prevention programs. Since dental hygienists are best suited for providing oral care to older adults with dementia, it is considered essential to reflect their occupation in future national policies.

• Child Health Nursing Research
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• v.25 no.2
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• pp.234-243
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• 2019

Purpose: The purpose of this study was to investigate associations between self-management and diabetes knowledge, diabetes-related attitudes, family support, and self-efficacy in adolescents with type 1 diabetes mellitus based on the information-motivation-behavior skills model. Methods: Data collection was conducted between March 18 and September 30, 2018. Patients (N=87) aged 12 to 19 years were recruited from the outpatient clinic of S children's hospital and an online community for patient with type 1 diabetes mellitus. Data were analyzed using descriptive statistics, the independent t-test, one-way ANOVA, Pearsons correlation, and hierarchical multiple linear regression with SPSS IBM 23.0, with the two-tailed level of significance set at 0.05. Results: The mean score of self-management in adolescents with type 1 diabetes mellitus was $61.23{\pm}10.00$ out of 80. The regression analysis showed that self-efficacy and family support significantly explained 56.9% of the variance in self-management (F=21.38, p<.001). Self-efficacy (${\beta}=.504$, p<.001) and family support (${\beta}=.188$, p<.001) were significant predictors of self-management. Conclusion: It is necessary to develop individual interventions to improve self-efficacy and family support for adolescents with type 1 diabetes mellitus to help them enhance their self-management.

• Journal of the Korean Magnetic Resonance Society
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• v.22 no.4
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• pp.149-157
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• 2018

Diabetes is known to be one of common causes for several types of peripheral nerve damage. Diabetic neuropathy (DN) is a significant complication lowering the quality of life that can be frequently found in diabetes patients. In this study, the metabolomic characteristic of DN and Diabetes was investigated with NMR spectroscopy. The sera samples were collected from DN patients, Diabetes patients, and healthy volunteers. Based on the pair-wise comparison, three metabolites were found to be noticeable: glucose, obviously, was upregulated both in DN patients (DNP) and Diabetes. Citrate is also increased in both diseases. However, the dietary nutrient and biosynthesized metabolite from glucose, ascorbate, was elevated only in DNP, compared to healthy control. The multivariate model of OPLS-DA clearly showed the group separation between healthy control-DNP and healthy control-Diabetes. The most significant metabolites that contributed the group separation included glucose, citrate, ascorbate, and lactate. Lactate did not show the statistical significance of change in t-test while it tends to down-regulated both in DNP and Diabetes. We also conducted the ROC curve analysis to make a multivariate model for discrimination of healthy control and diseases with the identified three metabolites. As a result, the discrimination model between healthy control and DNP (or Diabetes) was successful while the model between DNP and Diabetes was not satisfactory for discrimination. In addition, multiple combinations of lactate and citrate in the OPLS-DA model of healthy control and diabetes group (DNP + Diabetes patients) gave good ROC value of 0.952, which imply these two metabolites could be used for diagnosis of Diabetes without glucose information.

• The Journal of the Convergence on Culture Technology
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• v.5 no.3
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• pp.283-288
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• 2019

We propose a method to search for similar images by using outline lines and viewpoints. In the first test, the three-dimensional image, which can't control the motion, has lower search accuracy than the static flat image. For the cause analysis, six specific tropical fish data were selected. We made a 3D graphics of tropical fishes of each kind, and we made 144 image outline lines with 12 stage viewpoints of top, bottom, left and right. Tropical fish by type were collected and sorted by time of search through similar search. Studies have shown that there are many unique viewpoints for each species of tropical fish. To increase the accuracy of the search, a User Interface was created to select the user's point of view. When the user selects the viewpoint of the image, a method of showing the result in consideration of the range of the related viewpoint is proposed.

• Journal of the Korean Society of School Health
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• v.32 no.2
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• pp.67-76
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• 2019

Purpose: The purpose of this study was to explore self-directed learning ability and its affecting factors among undergraduate students. Methods: A descriptive cross-sectional study design was used. Using a convenience sampling method, data were collected from 196 undergraduate students enrolled in one national university. Negative psychological tendency (i.e. Type D personality), academic engagement, and self-directed learning ability were assessed using a structured questionnaire. Data were analyzed by descriptive statistics, t-test, and analysis of covariance, Pearson's correlation coefficients, and stepwise multiple linear regression, using SPSS/WIN 23.0 program. Results: The mean age of the students was $21.61{\pm}2.40years$ and 56.6% were male students. Approximately, one third (n=67, 34.2%) of the students had Type D personality. The average scores of academic engagement and self-directed learning ability were $3.01{\pm}1.14$ and $3.46{\pm}0.50$, respectively. After controlling for sociodemographic variables, the Type D personality and academic engagement were significant predictors of self-directed learning ability (${\beta}=.64$, p<.001; ${\beta}=-.13$, p=.021, respectively). This model explained 53.6% of the variance in self-directed learning ability. Conclusion: The study identified that Type D personality and academic engagement affect self-directed learning ability of undergraduate students, one in a negative way, the other in a positive way. Educators and educational policy makers need to make efforts to include interventions and strategies that increase academic engagement and change negative psychological dispositions such as D-type personality in the undergraduate education curriculum.