• Proceedings of the Korean Magnestics Society Conference
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• 2004.12a
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• pp.45-46
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• 2004

• Transactions of the Korean Society of Mechanical Engineers A
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• v.24 no.4 s.175
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• pp.907-915
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• 2000

The movement of teeth and initial stress associated with the treatment of orthodontics have been successfully studied using the finite element method. To reduce the effort in preprocessing of finite element analysis, we developed two types of three-dimensional finite element models based on the standard teeth model. Individual malocclusions were incorporated in the finite element The movement of teeth and initial stress associated with the treatment of orthodontics have been successfully studied using the finite element method. To reduce the effort in preprocessing of finite element analysis, we developed two types of three-dimensional finite element models based on the standard teeth model. Individual malocclusions were incorporated in the finite element models by considering the measuring factors such as angulation, crown inclination, rotation and translations. The finite element analysis for the wire activation with a T-loop arch wire was carried out. Mechanical behavior on the movement and the initial stress for the malocclusion finite element model was shown to agree with the objectives of the actual treatment. Finite element models and procedures of analysis developed in this study would be suitably utilized for the design of initial shape of the wire and determination of activation displacements.

• Proceedings of the Botanical Society of Korea Conference
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• 1999.07a
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• pp.11-15
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• 1999

In order to evlauate feasibility of the gene tagging by the maize transposable element Ac in heterologous plant systems, we have investigated physical distances and directions of transposition of the element in Arabidopsis thaliana and tobacco cultured cell line BY-2. We prepared a T-DNA construct that carried a non-autonomous derivative of Ac with a site for cleavage by endonuclease I-Scel (designated dAc-I-RS element). Another cleavage site was also introduced into the T-DNA region outside dAc-I-RS. A number of transgenic Arabidopsis plants were generated, each of which had a single copy of the T-DNA at a different chromosomal location. To examine the pattern of transposition, three out of these transgenic plants were crossed with the Arabidopsis plant that carried the gene for Ac transposase and progeny in which dAc-I-RS had been transposed were isolated. After digestion of the genomic DNA of these progeny with I-SceI, sizes of segment of DNA were determined byd pulse-field gel electrophoresis. We also performed linkage analysis for the transposed elements and sites of mutations near the elements. Our results with three transgenic lines showed that 50% of all transposition events had occurred within 1,700 kilo-base pairs (kb) on the same chromosome, with 35% within 200 kb, and that the elements transposed in both directions on the chromosome with roughly equal probability. The data thus indicate that the Ac-Ds system is most useful for tagging of genes that are present within 200 kb of the chromosomal site of Ac in Arabidopsis. In addition, determination of the precise localization of the transposed dAc-I-RS element should definitely assist in map-based cloning of genes around insertion sites. In the present paper, we report typical examples of such gene isolation studies.

• Structural Engineering and Mechanics
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• v.26 no.1
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• pp.69-86
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• 2007

A four-noded plate bending quadrilateral (PBQ4) and an eight-noded plate bending quadrilateral (PBQ8) element based on Mindlin plate theory have been adopted for modeling the thick plates on elastic foundations using Winkler model. Transverse shear deformations have been included, and the stiffness matrices of the plate elements and the Winkler foundation stiffness matrices are developed using Finite Element Method based on thick plate theory. A computer program is coded for this purpose. Various loading and boundary conditions are considered, and examples from the literature are solved for comparison. Shear locking problem in the PBQ4 element is observed for small value of subgrade reaction and plate thickness. It is noted that prevention of shear locking problem in the analysis of the thin plate is generally possible by using element PBQ8. It can be concluded that, the element PBQ8 is more effective and reliable than element PBQ4 for solving problems of thin and thick plates on elastic foundations.

• Journal of Korea Foundry Society
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• v.33 no.1
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• pp.13-21
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• 2013

The effects of rare earth element (R.E.) and cooling rate on the eutectic reaction of flake graphite cast irons were studied by combined analysis of macro/micro-structure and cooling curve data. The correlation between eutectic reaction parameter and macro/micro-structure was systematically investigated. Two sets of chemical compositions with the different addition of R.E. were designed to cast. Three types of molds for cylindrical specimens with the different diameters were prepared to analyze cooling rate effect. The difference between undercooling temperature and cementite eutectic temperature (${\Delta}T_1=T_{U}-T_{E,C}$), which is increased by adding R.E. and decreased by increasing cooling rate, is considered to be a suitable eutectic reaction parameter for predicting graphite morphology. According to the criterion, A-type graphite is mainly suggested to form for ${\Delta}T_1$ over $20^{\circ}C$. Eutectic reaction time (${\Delta}t$), which is decreased by adding R.E. or increasing cooling rate, is a suitable eutectic reaction parameter for predicting eutectic cell size. Eutectic cell size is found to decrease in a proportion to the decrease of ${\Delta}t$.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.11
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• pp.1191-1198
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• 2015

In this paper, we develop simplified finite element (FE) models for butt-, lap- and T-welded joints by performing numerical and experimental experiments. Three-point bending tests of butt- and lap-welded specimens are performed to obtain the stiffness of the specimens and the strains at points near the welding beads. Similarly the stiffness and strains of T-welded specimen are measured by applying a point load at the end of the specimen. To develop simplified FE models, we consider the shape parameters of width, thickness and the angle of weld elements in the numerical simulations. The shape parameters of the simplified FE models are determined by building linear regression models for the experimental data sets.

• BMB Reports
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• v.54 no.2
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• pp.106-111
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• 2021

Hemistepsin A (HsA) is a guaianolide sesquiterpene lactone that inhibits hepatitis and liver fibrosis. We evaluated the effects of HsA on liver X receptor (LXR)-mediated hepatic lipogenesis in vitro and in vivo. Up to 10 μM, HsA did not affect the viability of HepG2 and Huh7 cells. Pretreatment with 5-10 μM HsA significantly decreased the luciferase activity of the LXR response element, which was transactivated by T0901317, GW 3965, and LXRα/retinoid X receptor α overexpression. In addition, it significantly inhibited the mRNA expression of LXRα in HepG2 and Huh7 cells. It also suppressed the expression of sterol regulatory element-binding protein-1c and lipogenic genes and reduced the triglyceride accumulation triggered by T0901317. Intraperitoneal injection of HsA (5 and 10 mg/kg) in mice significantly alleviated the T0901317-mediated increases in hepatocyte diameter and the percentage of regions in hepatic parenchyma occupied by lipid droplets. Furthermore, HsA significantly attenuated hepatic triglyceride accumulation by restoring the impaired expression of LXRα-dependent lipogenic genes caused by T0901317. Therefore, based on its inhibition of the LXRα-dependent signaling pathway, HsA has prophylactic potential for steatosis.

• Journal of the Korean Mathematical Society
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• v.51 no.1
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• pp.67-86
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• 2014

Based on an expanded mixed finite element method, we consider the semidiscrete approximations of the solution u of the quasilinear pseudo-parabolic equation defined on ${\Omega}{\subset}R^d$, $1{\leq}d{\leq}3$. We construct the semidiscrete approximations of ${\nabla}u$ and $a(u){\nabla}u+b(u){\nabla}u_t$ as well as u and prove the existence of the semidiscrete approximations. And also we prove the optimal convergence of ${\nabla}u$ and $a(u){\nabla}u+b(u){\nabla}u_t$ as well as u in $L^2$ normed space.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2000.10a
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• pp.62-65
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• 2000

For saving time and cost of experiment Finite Element Method has been developed for several decades. It's the defect of FEM that when we are in processing of finite element analysis, the material if deformed so much that we can't proceed analysis any more. In this case, the remeshing process should be done on this material. In hot forging process, almost all remeshing process does not consider flash of the material. Because as mesh size become swatter, consuming time become larger. But if mesh size is big, there is the defect that the result of analysis is not so accurate. So, new remeshing algorithm is needed to save time and to get more accurate result.

• Transactions of Materials Processing
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• v.23 no.1
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• pp.29-34
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• 2014

The damage level of the die surface was predicted by estimating the surface roughness with a finite element analysis and the wear characteristics. Wear and friction tests were conducted to compare the wear characteristics for three kinds of surface treatments - CrN, TiAlN and AlCrN coatings. A prediction model was derived from the surface roughness results with respect to contact pressure and sliding speed which were obtained from the wear test. Surface roughness values for the damage regions of the die surface were compared between the experiments and the prediction model, which shows fairly good agreement with each other.