• Journal of agricultural medicine and community health
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• v.18 no.1
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• pp.65-75
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• 1993

This study was conducted to compare the frequency and to find epidemiologic characteristics of the diseases by analyzing the results of routine first health examination for partial healthy public officials. The total number of the examined was 1.128(876 male, 252 female) The results were as follow; 1. The prevalence rate of suspicious disease was liver disease 5.9% hypertension 5.4%, hyperlipemic disease 3.8%, pulmonary tuberculosis 1.2% by order. 2. The mean systolic blood pressure and diastolic blood pressure showed increasing trend by age increasing. The mean of blood pressure in man was rather higher than that in woman. 3. The prevalence rate of suspicious borderline hypertension increased by aging. And the distribution of high cholesterol group and over than overweight group increased by aging. 4. In male, significant relation among age, systolic blood pressure, diastolic blood pressure, relative body weight was found. And significant relation between total cholesterol level and relative body weight was found. In female, age and relative body weight was related to systolic blood pressure, diastolic blood pressure and total cholesterol level. 5. According to the retrospective follow-up for those who had suspicious disease, correspondence rate of results was 5.2% in circulatory disease and 1.5% in liver disease.

• Biomolecules & Therapeutics
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• v.7 no.4
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• pp.322-328
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• 1999

In this study, it was tested whether the changes of catecholamines and its metabolites are related with the changes of blood pressure(BP) induced by different levels of lead exposure. Adult male SD rats were exposed to lead by giving drinking water containing 50(low doses), 200 and 1,000 ppm(high doses) of lead(as lead acetate) or sodium acetate(for control groups, supplying an identical amount of acetate) for 7 or 16 weeks. The systolic BP was measured in the unanesthetized state by the tail-cuff technique. Levels of catecholamines and its metabolites in urine were measured by HPLC-ECD. Rats receiving 200 and 1,000 ppm developed an elevation of systolic BP at 3 and 7 weeks compared with week 0, but blood pressure levels at 16 weeks returned to normal. For the 50 ppm lead treated group, systolic BP increased significantly at 7 weeks and 16 weeks. The concentrations of norepinephrine and VMA in the urine of lead exposed rats changed similarly to the changes of blood pressure, but blood viscosity levels in all lead treated rats increased continuously during all lead treatment periods. This result suggests that the changes of catecholamines and its metabolites in urine by lead intoxication may influence the changes of blood pressure.

• Journal of Nutrition and Health
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• v.22 no.2
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• pp.91-101
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• 1989

This study was performed to investigate the effects of different dietary magnesium levels on systolic blood pressure and mineral distribution in normotensive and spontaneously hypertensive rats. In experiment 1, Normotensive rats(NTR ; Sprague Dawley, Female) were given diets containing regular magnesium (0.05% Mg ; rMg), marginal magnesium (0.01% Mg ; mMg) or marginal magnesium with stress(0.01% Mg + stress ; mMg + Str). In experiment 2, spontaneously hypertensive rats (SHR ; Kyoto Wistar, Femal) were fed diets containing regular magnesium(0.05% Mg ; rMg) and high magnesium (0.2% Mg ; hMG). The following were found ; 1) NTR treated with marginal magnesium with stress showed significant increase in systolic blood pressure (SBP). Marginal magnesium diet without stress resulted in nonsignificant increase in SBP. Significant in crease of blood pressure showed in NTR treated with marginal magnesium and stress was associated with decreased magnesium and increased calcium content in femur, reticulocyte and plasma. 2) In experiment 2, magnesium supplementation to SHR showed significant attenuation of their systolic blood pressure with increasing age. The attenuation of SBP showed in SHR was associated with increased magnesium, lowered calcium content in cardiac muscle and reticulocyte and decreased plasma sodium and aldosterone level.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.1
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• pp.75-80
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• 2019

Purpose : This study investigated the effect of bamboo stepping exercises on the blood pressure of the elderly. This study was performed for 8 weeks. Methods : The study participants included 25 people aged 65 and over. Of the participants, 16 were in the hypertensive elderly group and 9 were in the normal blood pressure elderly group. The participants stepped on semicircular bamboo for 20 minutes 3 times a week for 8 weeks. The participants' blood pressure was measured 3 times before and after 8 weeks of exercise. The mean values of the 3 before and after measurements were compared and analyzed statistically. Results : The systolic blood pressure of the hypertensive elderly group decreased significantly from $134.6{\pm}21.1mmHg$ to $119.9{\pm}18.1mmHg$ (p<.05). The diastolic blood pressure of the hypertensive elderly group decreased from $70.2{\pm}10.5mmHg$ to $66.1{\pm}9.8mmHg$, but the difference was not significant. The systolic blood pressure of the normal blood pressure elderly group decreased significantly from $127.2{\pm}18.7mmHg$ to $115.5{\pm}19mmHg$ (p<.05). The diastolic blood pressure of the normal blood pressure elderly group decreased from $72.6{\pm}11.3mmHg$ to $68.2{\pm}12mmHg$, but the decrease was not significant. Conclusion : After completing 8 weeks of the bamboo stepping exercises, the elderly participants' systolic blood pressure was effectively reduced. Today, lifestyle modifications, such as daily exercise, are necessary to control the blood pressure of the elderly. We hope that the bamboo stepping exercises, which are easy to perform and are not restricted by place and time, will become part of the elderly health policy.

• Korean Journal of Clinical Laboratory Science
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• v.52 no.1
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• pp.45-52
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• 2020

Hypertension often leads to cardiovascular disease and kidney disease, and hypertention is an important worldwide problem. Body mass index (BMI) has an important role for raising blood pressure. Further, hypertension can be affected by both environmental factors and genetic factors. Many single nucleotide polymorphisms have been associated with hypertension. Genome wide association study (GWAS) is a method of confirming a new locus of increasing the risk of disease, and GWAS has confirmed several single nucleotide polymorphisms (SNPs) that are associated with high blood pressure. This study analyzed the relationship between systolic blood pressure, diastolic blood pressure and SNP of the ATP2B1 gene in 994 Koreans. SNPs that showed the highest statistical significance with systolic and diastolic blood pressures were selected on the multiple linear regression analysis. One-way analysis of variance for systolic and diastolic blood pressures was performed, and multiple logistic regression analysis was performed on the risk of hypertension. The P values were two-tailed, and P<0.05 was considered significant. Four SNPs were associated with systolic blood pressure and six SNPs were associated with diastolic blood pressure. In addition, a genotype-based analysis showed significant odds ratios for the risk of hypertension in older men (adjusted OR, 5.743; 95% CI, 1.173~28.121; P=0.031). This study suggests that the ATP2B1 variants affect both the systolic and diastolic blood pressure.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.6
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• pp.1045-1049
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• 1996

Purpose of this study was to investigate correlation between blood pressure(systolic and diastolic) and dietary Na, K intake pattern in the family members of normal and hypertension disease patients, besides patients themselves. Mean values of $systolic(126.6\pm18.0$ vs $119.3\pm17.2mmHg)$ and diastolic $(77.6\pm14.6$ vs $71.6\pm12.5mmHg)$ blood pressure in the family members of hypertension patients were significantly higher than those of normal subjects. Systolic blood pressure in normal subject group was positively correlated with age, body weight, sodium in soybean paste, and was negatively correlated with potassium in hotpepper paste, soybean paste and meats. Systolic blood pressure in the family member of hypertension patient was positively correlated with age, body weight, sodium in soybean Paste, and table salt intake, but urinary potassium excretion was negatively correlated. Diastolic blood pressure was positively correlated with age, body weight, and table salt intake, and was negatively correlated with potassium in hotpepper paste and soybean paste in normal subjects groups. In the family members of hypertension patients group, diastolic blood pressure was positively correlated with age, body weight, and table salt intake, and was negatively correlated with sodium in hotpepper Paste and soybean paste and urinary potassium excretion. In total, tendency of negative correlation between Na intake pattern and systolic blood pressure in normal subjects was much obvious than that in the family members of hypertension patients. Urinary potassium excretion in the family members of hypertension patients was also negatively correlated with both systolic and diastolic blood pressure.

• Journal of Preventive Medicine and Public Health
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• v.31 no.3 s.62
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• pp.384-394
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• 1998

In order to investigate the effect of the urinary excretion of sodium and potassium on the change on blood pressure over 3 years, 668 adolescents aged 13 years living in Kangwha area were investigated in a longitudinal follow-up study. Two measurements were taken on each blood pressure (diastolic, systolic) and the average of the two readings was used in the analysis. Sodium and potassium intake were estimated by the determination of those electrolytes in 24hr urine. The mixed model regression analysis was used to identify the effect of urinary sodium and potassium on the change of blood pressure after controlling for BMI of each age. On simple bivariate analysis no relationship was found between urinary sodium excretion and systolic or diastolic blood pressure among both male and female, however, a significant positive association between urinary potassium excretion and systolic blood pressure among male. The results of mixed regression analysis showed that the body mass index (BMI) were more influential that urinary electrolytes among this study subjects. It suggested that risk factors observed from the adults, may not be identical with that of the growing aged population. After control of the BMI and age, significant association between sodium and diastolic BP among male, and association between potassium and systolic BP among female, were found. In summary, the results indicate that growth has been more influential than dietary factor on blood pressure for growing aged population.

• Korean Journal of Acupuncture
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• v.24 no.1
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• pp.27-41
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• 2007

Objectives : The aim of this study was to investigate the antihypertensive effect of Korean Gogoon Acupuncture in hypertensive patients. Methods : We measured the blood pressure of 17 patients who were admitted in the Oriental Medical Clinic of Gogoon Institute from 14th April 2006 to 29th August 2006. Eligible participants had systolic blood pressure ${\geq}120$ mmHg or diastolic blood $pressure{\geq}80$ mmHg. Blood pressure and pulse rate measurements were after the patient had been in bed rest for at least 30 min. Six sessions of Gogoon Acupuncture treatment over three weeks were performed in the patients. Blood pressure and pulse rate were measured twice before and after each acupuncture treatment. Results : After 3 weeks, there were significant decreases in systolic blood pressure(p=0.0028), diastolic blood pressure (p=0.0111) and pulse rate (p=0.0150). The effects of Gogoon Acupuncture by measuring time on blood pressure were as follows : In a systolic blood pressure (p<.0001) and diastolic blood pressure (p=0.0028) was gradually deceased significantly from 1st to 6th but pulse rate was not significantly decreased. Conclusions : Controlled trials investigating the efficacy of Gogoon acupuncture for lowering blood pressure are warranted.

• Journal of People, Plants, and Environment
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• v.22 no.5
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• pp.445-454
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• 2019

This study was conducted to find out physical changes in the blood pressure and saliva cortisol of patients with high blood pressure and diabetes after participating in agro-healing activities. The saliva cortisol and blood pressure of 14 males and females aged 49.79±10.48 on average were measured after participating in agro-healing activities. The saliva collection system was used, and their satisfaction level for the program was also surveyed. Changes in the values before and after participating in the agro-healing activities were compared and analyzed. The cortisol concentration, a stress hormone, was reduced from 6.76nmol/L before the program to 4.86nmol/L after the program, down by 1.9nmol/L, which was a statistically significant difference (z=-3.170, p<.01). In addition, the cortisol concentration was gradually reduced through the entire program from Session 1 to Session 7. Changes in the blood pressure of subjects before and after participating in agro-healing activities were examined, and the total systolic and diastolic blood pressure continuously decreased after participating in agro-healing activities through the entire program from Session 1 to Session 7. Their systolic blood pressure was reduced statistically significantly (z=-1.947, p<.05). Also, participants' satisfaction was analyzed and it was found that more than 95% of participants answered 'satisfied' and 'very satisfied' with agro-healing activities. Therefore, these results indicate that agro-healing activities performed in the healing-farm had a positive impact on the cortisol concentration and blood pressure of patients with chronic diseases such as diabetes and high blood pressure. In addition, their high satisfaction for this program seemed to improve the psychological and physiological conditions of subjects.

• The Korean Journal of Food And Nutrition
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• v.30 no.2
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• pp.257-268
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• 2017

The purpose of this research was to evaluate the correlation between obesity, threshold of salty taste, optimal saltiness and blood pressure in middle school students in a fishing village. The subjects were 115 boys and 103 girls in middle school in a fishing village. The BMI index and systolic and diastolic blood pressures of subjects were measured, and the subjects were divided into a normal and obese group according to their BMI. The threshold of salty taste and salt preference for a semisolid dish (steamed egg dish), liquid dish (bean sprout soup), and a solid dish (raw radish salad), were estimated by sensory evaluation. Calorie intake was measured using the weighing plate method. The boys in the obese group showed significantly higher systolic and diastolic blood pressures than those in the normal, but girls did not. Furthermore, calorie intakes of the boys in the obese group were significantly higher than those in the normal group, but this was not shown in girls. On the threshold of salty taste, both boys and girls in the obese group needed higher concentration of salt than those in the normal group. The threshold of salty taste were significantly positively correlated with systolic pressure and diastolic pressure in boys. Regarding the salt preference in the steamed egg dish, bean-sprout soup, and raw radish salad, both boys and girls in the obese group preferred higher concentrations. The higher concentration they preferred, the higher the systolic and diastolic pressures were in boys, but only systolic blood pressure was higher in girls. From these results, it is evident that a nutritional education program is needed in school to help restricting middle school students salt consumption and decreasing obesity to prevent hypertension.