• 제목/요약/키워드: Systolic

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CT Fractional Flow Reserve for the Diagnosis of Myocardial Bridging-Related Ischemia: A Study Using Dynamic CT Myocardial Perfusion Imaging as a Reference Standard

  • Yarong Yu;Lihua Yu;Xu Dai;Jiayin Zhang
    • Korean Journal of Radiology
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    • 제22권12호
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    • pp.1964-1973
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    • 2021
  • Objective: To investigate the diagnostic performance of CT fractional flow reserve (CT-FFR) for myocardial bridging-related ischemia using dynamic CT myocardial perfusion imaging (CT-MPI) as a reference standard. Materials and Methods: Dynamic CT-MPI and coronary CT angiography (CCTA) data obtained from 498 symptomatic patients were retrospectively reviewed. Seventy-five patients (mean age ± standard deviation, 62.7 ± 13.2 years; 48 males) who showed myocardial bridging in the left anterior descending artery without concomitant obstructive stenosis on the imaging were included. The change in CT-FFR across myocardial bridging (ΔCT-FFR, defined as the difference in CT-FFR values between the proximal and distal ends of the myocardial bridging) in different cardiac phases, as well as other anatomical parameters, were measured to evaluate their performance for diagnosing myocardial bridging-related myocardial ischemia using dynamic CT-MPI as the reference standard (myocardial blood flow < 100 mL/100 mL/min or myocardial blood flow ratio ≤ 0.8). Results: ΔCT-FFRsystolic (ΔCT-FFR calculated in the best systolic phase) was higher in patients with vs. without myocardial bridging-related myocardial ischemia (median [interquartile range], 0.12 [0.08-0.17] vs. 0.04 [0.01-0.07], p < 0.001), while CT-FFRsystolic (CT-FFR distal to the myocardial bridging calculated in the best systolic phase) was lower (0.85 [0.81-0.89] vs. 0.91 [0.88-0.96], p = 0.043). In contrast, ΔCT-FFRdiastolic (ΔCT-FFR calculated in the best diastolic phase) and CT-FFRdiastolic (CT-FFR distal to the myocardial bridging calculated in the best diastolic phase) did not differ significantly. Receiver operating characteristic curve analysis showed that ΔCT-FFRsystolic had largest area under the curve (0.822; 95% confidence interval, 0.717-0.901) for identifying myocardial bridging-related ischemia. ΔCT-FFRsystolic had the highest sensitivity (91.7%) and negative predictive value (NPV) (97.8%). ΔCT-FFRdiastolic had the highest specificity (85.7%) for diagnosing myocardial bridging-related ischemia. The positive predictive values of all CT-related parameters were low. Conclusion: ΔCT-FFRsystolic reliably excluded myocardial bridging-related ischemia with high sensitivity and NPV. Myocardial bridging showing positive CT-FFR results requires further evaluation.

재가 노인의 체위성 저혈압 발생빈도와 위험요인 (Prevalence and Risk Factors of Orthostatic Hypotension among the Community-Dwelling Aged)

  • 유수정;송미순;김현숙
    • 대한간호학회지
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    • 제33권2호
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    • pp.200-209
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    • 2003
  • Purpose: This study was to identify the prevalence of orthostatic hypotension and its association with risk factors of orthostatic hypotension aged over 60 in Seoul and Chungju, Korea. Method: The data were collected from the 22th of August, 2000 to the 7th May 2001. The participants were 74 community-dwelling aged who could stand up from sitting position without assistance. Subjects were interviewed with structured questionnaire in order to ask experience of previous falls, hours in per day, symptoms related orthostatic hypotension and demographic characteristics. Orthostatic hypotension was assessed at 1 minute after the subjects standing from sitting position and defined as 20mmHg or greater decrease in systolic blood pressure after standing. Result: The prevalence of orthostatic hypotension was 17.1%. The mean drop of systolic blood pressure was 27.46mmHg among orthostatic hypotension subjects. The significant variables which explain the occurrence of orthostatic hypotension was the basal systolic blood pressure, the hit ratio of discriminant function with basal systolic blood pressure was 69.7%. Conclusion: Finding indicate that this study will contribute to develop nursing strategies to identify risk factors and to prevent orthostatic hypotension for the aged.

30-69세 성인의 공복혈당장애와 당뇨병의 유병률과 위험인자 분석 (Prevalence and Risk Factors for Diabetes Mellitus and Impaired Fasting Glucose of Adults)

  • 김희승;노유자;김남초;유양숙;용진선;오정아
    • 대한간호학회지
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    • 제30권6호
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    • pp.1479-1487
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    • 2000
  • This study was conducted to draw out prevalence and the risk factors of diabetes mellitus and impaired fasting glucose for adults,(age 30-69). The subjects were 2096 adults, who had regular health examinations between January and December of 1999 at K Hospital in Seoul. The data was analyzed using chi-square test, unpaired t-test and logistic regression. Diabetes Mellitus and impaired fasting glucose were diagnosed by ADA (American Diabetes Association, 1997) criteria. The results were as follows: 1. Mens' prevalence of Diabetes Mellitus was 7.9% and womens' prevalence of Diabetes Mellitus was 3.8%. Mens' prevalence of impaired fasting glucose was 10.4% and womens' prevalence of impaired fasting glucose was 6.5%. Prevalences of Diabetes Mellitus and impaired fasting glucose increased with age. 2. Prevalence of Diabetes Mellitus and impaired fasting glucose of obese subjects (relative body weight>=162) was higher than that of overweight subjects (110<=relative body weight<=119) in men and women. 3. The diagnoses of Diabetes Mellitus and impaired fasting glucose increased with systolic blood pressure and triglyceride. 4. Significant factors associated with diabetes in the logistic regression best gut model were age, relative body weight, systolic blood pressure, triglyceride in men, and systolic blood pressure in women. In conclusion, as age, weight, systolic blood pressure and triglyceride get higher, Diabetes Mellitus and impaired fasting glucose prevalence also increases, porportionally.

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앙와위에서 직립자세로의 체위변화가 정상인의 순환에 미치는 영향 (Effect of changing position from supine to standing up-right on the circulation in young men and women)

  • 최명애;김종임;김현리
    • 대한간호학회지
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    • 제19권3호
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    • pp.285-298
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    • 1989
  • This study investigated the effect of changing position from supine to standing upright on the circulation of young men and women. Healthy men and women ranging from age of 18 to 24 were examined. Two minutes before standing, the baseline heart rate and blood pressure were measured. Heart rate and blood pressure were recorded immediately and at every minute for 10 minutes after standing upright. Differences in heart rate and blood pressure between supine and standing upright position were evaluated. The results were summarized as follows : 1. Heart rate increased significantly immediately and at every minute for 10 minutes after standing upright. 2. Systolic blood pressure increased significantly immediately and at every minute for 4 minutes after standing upright. 3. Diastolic and mean blood pressure increased significantly immediately and at every minute for 10 minutes after standing upright. 4. Pulse pressure immediately and at every minute for 10 minutes after standing upright was significantly narrower than that of supine position. 5. There was no significant difference of heart rate between men and women after standing upright. 6. Systolic and diastolic blood pressure of men after standing upright was significantly greater than those of women. From these results, it may be concluded that heart rate, systolic, diastolic and mean blood pressure and pulse pressure increase after standing upright, and systolic and diastolic blood pressure in men is greater than those of women after standing upright.

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Low-Power and Low-Hardware Bit-Parallel Polynomial Basis Systolic Multiplier over GF(2m) for Irreducible Polynomials

  • Mathe, Sudha Ellison;Boppana, Lakshmi
    • ETRI Journal
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    • 제39권4호
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    • pp.570-581
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    • 2017
  • Multiplication in finite fields is used in many applications, especially in cryptography. It is a basic and the most computationally intensive operation from among all such operations. Several systolic multipliers are proposed in the literature that offer low hardware complexity or high speed. In this paper, a bit-parallel polynomial basis systolic multiplier for generic irreducible polynomials is proposed based on a modified interleaved multiplication method. The hardware complexity and delay of the proposed multiplier are estimated, and a comparison with the corresponding multipliers available in the literature is presented. Of the corresponding multipliers, the proposed multiplier achieves a reduction in the hardware complexity of up to 20% when compared to the best multiplier for m = 163. The synthesis results of application-specific integrated circuit and field-programmable gate array implementations of the proposed multiplier are also presented. From the synthesis results, it is inferred that the proposed multiplier achieves low power consumption and low area complexitywhen compared to the best of the corresponding multipliers.

Clock-gating 방법을 사용한 저전력 시스톨릭 어레이 비터비 복호기 구현 (Low-Power Systolic Array Viterbi Decoder Implementation With A Clock-gating Method)

  • 류제혁;조준동
    • 정보처리학회논문지A
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    • 제12A권1호
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    • pp.1-6
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    • 2005
  • 본 논문에서는 trace-back systolic array Viterbi algorithm의 저전력 생존 메모리 구현에 관한 새로운 알고리즘을 소개한다. 이 알고리즘의 핵심 아이디어는 trace back 연산의 수를 줄이기 위하여 이미 생성된 trace-back routes를 재사용하는 것이다. 그리고 trace-back unit의 불필요한 switching activity가 발생하는 영역을 gate-clock을 사용하여 전력소모를 줄이는 것이다. Synopsys Power Estimation 툴인 Design Power를 이용하여 전력소모를 측정하였고, 그 결과 [1]의 논문에서 소개된 trace-back unit 비하여 평균 $40{\%}$ 전력감소가 있었고, $23{\%}$의 면적증가를 보였다.

과량수혈이 혈역학에 미치는 영향 (Hemodynamic effects of induced overtransfusion of blood in dogs)

  • 기노석
    • Journal of Chest Surgery
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    • 제17권3호
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    • pp.418-423
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    • 1984
  • Appreciation of the large volume deficits which may occur in surgical or trauma patients due to blood loss has led to vigorous transfusion techniques designed to overt hypovolemic shock and ischemic damage to vital organs which may develop in minutes during the hypovolemic state. In a significant proportion of patients treated with massive rapid blood or fluid transfusion, hypervolemia occurs and life threatening pulmonary edema may develop. Especially, hypervolemia may occur during transfusion for preventing development of the so-called low output syndrome following cardiac surgery. However, the most effective indicator which reveals the adequate level of transfusion is not settled yet. The present study was aimed to compare the effectiveness of the indicators suggested thus far and to determine the most sensitive one. Eight dogs were experimentally studied in terms of left atrial pressure, pulmonary arterial systolic pressure, central venous pressure, mean systemic arterial pressure and heart rate before and after induced hypervolemia with infusion of 600ml heparinized homologous blood. Immediately after induced overtransfusion of the blood, pulmonary arterial systolic pressure increased 75.0%, in omparison with the control before transfusion, left atrial pressure 58.8%, central venous pressure 44.6%, and mean systemic arterial pressure 10.1%, one hour after transfusion, pulmonary arterial systolic pressure 40.0%, left atrial pressure 21.2%, central venous pressure 14.5%, and mean systemic arterial pressure 3.2%, central venous pressure 14.5%, and mean systemic arterial pressure 3.2%, respectively. Heart rate showed no significant change throughout the experiment. These result suggested that the changes of the pulmonary arterial systolic pressure is the most sensitive indicator for detection of hypervolemia during blood transfusion.

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정상 혈압쥐와 본태성 고혈압쥐에 있어 식이상의 마그네슘 섭취가 수축기 혈압과 전해질 배분에 미치는 영향 (The Effects of Dietary Magnesium on Systolic Blood Pressure and Electrolyte Distribution in Normotensive and Spontaneously Hypertensive Rat)

  • 배현수
    • Journal of Nutrition and Health
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    • 제22권2호
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    • pp.91-101
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    • 1989
  • This study was performed to investigate the effects of different dietary magnesium levels on systolic blood pressure and mineral distribution in normotensive and spontaneously hypertensive rats. In experiment 1, Normotensive rats(NTR ; Sprague Dawley, Female) were given diets containing regular magnesium (0.05% Mg ; rMg), marginal magnesium (0.01% Mg ; mMg) or marginal magnesium with stress(0.01% Mg + stress ; mMg + Str). In experiment 2, spontaneously hypertensive rats (SHR ; Kyoto Wistar, Femal) were fed diets containing regular magnesium(0.05% Mg ; rMg) and high magnesium (0.2% Mg ; hMG). The following were found ; 1) NTR treated with marginal magnesium with stress showed significant increase in systolic blood pressure (SBP). Marginal magnesium diet without stress resulted in nonsignificant increase in SBP. Significant in crease of blood pressure showed in NTR treated with marginal magnesium and stress was associated with decreased magnesium and increased calcium content in femur, reticulocyte and plasma. 2) In experiment 2, magnesium supplementation to SHR showed significant attenuation of their systolic blood pressure with increasing age. The attenuation of SBP showed in SHR was associated with increased magnesium, lowered calcium content in cardiac muscle and reticulocyte and decreased plasma sodium and aldosterone level.

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구심성, 원심성, 등척성 운동방법에 따른 혈압과 심박수의 변화 (Blood Pressure and Heart Rate Responses to Concentric, Eccentric, Isometric Exercises)

  • 정연태;김기훈;구애련;한소영
    • 한국전문물리치료학회지
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    • 제1권1호
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    • pp.75-82
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    • 1994
  • The purpose of this study is to determine cardiovascular reponses to concentric, eccentric and isometric exercise applied to the knee extensor muscle group. Exercise types studied were concentric, eccentric and isometric. The subjects were sixty healthy male volunteers who had no hypertension or cardiac disease. Heart rate, systolic and diastolic blood pressure were recorded prior to starting exercise. The subjects also performed 10RM on right lower extremity. A N-K table was used for three exercises to right knee extensors. Each exercise was selected randomly and applied to each subject 10 times in a 10 second. After each exercise, heart rate, systolic and diastolic blood pressure were recorded immediately. Findings were as follows concectric contractions had a greater effect on the increase of systolic blood pressure and heart rate than eccentric or isometric contractions. Diastolic blood pressure is influenced only by isometric contractions. Eccentric contractions have less effect on the increase of systolic blood pressure and heart rate than concentric or isometric contractions. We hope that the results of this experiment can be adapted to exercise programs for patients with cardiac disease.

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$CF(2^m)$상의 LSD 우선 곱셈을 위한 새로운 시스톨릭 어레이 (A New Systolic Array for LSD-first Multiplication in $CF(2^m)$)

  • 김창훈;남인길
    • 한국통신학회논문지
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    • 제33권4C호
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    • pp.342-349
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    • 2008
  • 본 논문에서는 암호 응용을 위한 $CF(2^m)$상의 새로운 디지트 시리얼 시스톨릭 곱셈기를 제안한다. 제안된 곱셈기는 연속적인 입력 데이터에 대해 ${\lceil}m/D{\rceil}$ 클럭 사이클마다 곱셈 결과를 출력한다. 여기서 D는 선택된 디지트 크기이다. 기존에 제안된 구조들은 선형의존성 때문에 디지트 크기 D가 증가하면 최대 처리기 지연시간 역시 선형으로 증가하지만 제안된 곱셈기는 이진트리 형태의 내부 구조를 가지기 때문에 D에 대해 로그단위로 증가한다. 따라서 제안된 구조는 기존에 제안된 디지트 시리얼 시스톨릭 곱셈기에 비해 계산지연을 상당히 감소시킨다. 뿐만 아니라 제안된 곱셈기는 규칙성, 모듈성, 단방향 신호 흐름의 특성을 가지기 때문에 VLSI 구현에 매우 적합하다.