• 한국유전체학회:학술대회논문집
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• 한국유전체학회 2004년도 The 13th Korea Genome Conference
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• pp.50.1-50.1
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• 2004

• 한국산업보건학회지
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• 제33권2호
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• pp.188-205
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• 2023

Objectives: Methanol poisoning accidents in smartphone parts manufacturing facilities were analyzed using a systemic accident analysis method, and the necessity and possibility of the application of this systemic method in the field of occupational health were reviewed. Methods: A STAMP model for accident analysis was created based on the previously published literature. CAST analysis was performed to find the causal factors of the components and between the components. Results: The STAMP model visually showed the abstract and complex system control structure. The CAST analysis results could include all the causal factors from the previously published literature, and presented them holistically. Additional causal factors that were not presented in the literature were found. Conclusions: The holistic accident analysis results in this study will be helpful to establish comprehensive measures to prevent methanol or other chemical poisoning accidents. Therefore, it will be necessary to use systemic accident analysis methods in the field of occupational health.

• 대한치과기공학회지
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• 제42권1호
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• pp.55-64
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• 2020

Purpose: The purpose of this study was to investigate the relationship between systemic diseases and denture wear status in elderly. The subjects of this study were 4,340 seniors aged 65 or older who conducted screenings and health surveys using the National Health and Nutrition Survey data during the sixth period (2013, 2014 and 2015). Methods: For the general characteristics and denture wear status according to general systemic diseases, complex sample frequency analysis and cross-analysis were performed. After controlling the general characteristics, complex sample logistic regression analysis was performed to determine the relationship between systemic diseases and denture wear status. Statistical software was used for SPSS (SPSS 23.0 for Windows, SPSS Inc, USA). Significance level was considered as 0.05. Results: A multisample logistic regression analysis was performed to determine the relationship between systemic diseases and denture wear status. The results showed that the dentured state had a significant effect on dyslipidemia and diabetes. Conclusion: Dyslipidemia and diabetes, which are related to denture wearing condition, need to be prevented and treated with regular checkups. In addition, based on the results of the study, it is thought that the elderly need denture prosthetic treatment after tooth extraction. In addition, it can be used as basic data for oral health business plan that can maintain and manage oral health.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2191-2194
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• 2014

Background: Fluorouracil-based regimens have been widely accepted and recommended in the guidelines for treating patients with early or advanced staged colon cancer, although results are controversial. Here we performed a systemic analysis to evaluate the impact of S-1 based regimens on response and survival of patients with colon cancer. Methods: Clinical studies evaluating the impact of S-1 based regimens on response and survival of patients with colon cancer were identified using a predefined search strategy. Summary response rates (RRs) to treatment were calculated. Results: Six clinical studies which including 227 patients with advanced colorectal cancer were considered eligible for inclusion. Two studies were conducted using combination of S-1 and Oxaliplatin, and four studies featured S-1 and irinotecan. Systemic analysis showed that, in all patients, pooled RRs was 43.17%. Major adverse effects were hematological toxicities, gastrointestinal disturbance, neurosensory toxicity. No treatment related death occurred. Conclusion: This systemic analysis suggests that S-1 based regimens, both with oxaliplatin or irinotean are associated with acceptable response and toxicity in patients with colon cancer.

• 고신대학교 의과대학 학술지
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• 제33권3호
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• pp.289-296
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• 2018

Objectives: In these days, patients with stage I breast cancer have increased by regular health examination and diagnostic tool development. The aim of this retrospective study is to identify systemic recurrence related factors after breast conserving surgery (BCS) for stage I breast cancer. Methods: In this study, we analyzed the correlation between systemic recurrence and pathologic factors. We reviewed 223 patients who underwent BCS for stage I breast cancer. Postoperative pathologic factors, recurrent rates and sites were studied. In addition, preoperative patients'data were also collected. Statistical analysis was done by using PASW 16.0 (SPSS Inc., Chicago, IL, USA). Results: Systemic recurrence was found in 16 patients (7.17%) within 5 years after primary surgery. 5 patients had lymphatic invasion and 6 patients had vascular invasion. Lymphatic and vascular invasion had statistical correlation with systemic recurrence (P = 0.004, P = 0.001). Conclusions: In this retrospective study, we can conclude that vascular invasion and lymphatic invasion are related systemic recurrence after BCS for stage I patients. Further studies with large cohort will be required to fully understand the risk factors of systemic recurrence for stage I breast cancer patients.

• BMB Reports
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• 제41권11호
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• pp.778-783
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• 2008

Turnip yellow mosaic virus (TYMV) RNA has two hairpins in its 5' untranslated region (5'-UTR). To investigate the role of the hairpins in replication of TYMV, mutants lacking one or both of the two hairpins were constructed. The TYMV constructs were introduced into Chinese cabbage by an Agrobacterium-mediated T-DNA transfer method, called agroinfiltration. Analysis of total RNA from agroinfiltrated leaves showed that replication of the mutant TYMV RNA lacking both hairpins was about 1/100 of wild type. This mutant was also impaired in systemic spread. Deletion analysis of each hairpin revealed that both hairpins were needed for maximal replication. The deletion analysis along with sequence modification of the hairpin structure indicates that the second hairpin plays a role in efficient long-distance systemic movement of TYMV.

• 한국치위생학회지
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• 제22권3호
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• pp.189-197
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• 2022

Objectives: The purpose of this study was to investigate the level of systemic disease-related knowledge among dental hygienists and analyze the effect on their job performance, empowerment, and satisfaction to provide basic data for expanding education on systemic diseases among dental hygienists and improving their job performance, empowerment and satisfaction. Methods: A survey was conducted among dental hygienists working in Busan and Gyeongsangnam-do region, South Korea, from October 27 to November 10, 2020, with a total of 245 questionnaires included in the final analysis. Results: Results of analysis revealed an average score for systemic disease-related knowledge among dental hygienists of 16.53±3.33 points and the higher the systemic disease-related knowledge, the higher the job performance, empowerment, and satisfaction. The higher the coronary artery disease knowledge and respiratory and infectious disease knowledge, the higher the job performance, and the higher the respiratory and infectious disease knowledge, the higher the job empowerment and job satisfaction. Conclusions: This study revealed that the higher dental hygienists' level of systemic disease-related knowledge, the higher their job performance, empowerment, and satisfaction. Therefore, this study suggests that dental hygienists' education on systemic disease-related knowledge should be expanded, and diverse systemic disease education programs should be developed for application in clinical practice.

• Educational Technology International
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• 제8권2호
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• pp.73-91
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• 2007

The purpose of this study is to explore tools for systemic and integrated teaching analysis in recognition of problems derived from the existing teaching analysis which have been held fragmentarily and temporarily. In order to do so, a teaching analysis tools is identified by examining the current services of video-taping and analysis, which are the most representative teaching analysis methods among the Centers for Teaching and Learning (CTLs) in Korea, and by redefining teaching analysis through literature review. A teaching analysis is to be done to challenge teachers to change and grow by providing a motive to reflect on the act of teaching and carry out improvements, and it has to be held covering the general act of teaching and examined through diverse methods in systemic and multidimensional perspectives over a full period of teaching. In this study, an act of teaching is examined in four areas: planning, teaching skill, evaluation and reflection, and teaching analysis frameworks according to an act of teaching are suggested by periods of before, during, and after a term. Teaching analysis methods are also suggested by the frameworks.

• 유통과학연구
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• 제15권11호
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• pp.21-29
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• 2017

Purpose - Relationship between farm and county losses determines whether the county program provides too little, too much, or similar amount of assistance relative to the loss on an individual farm. A review of the literature finds limited analysis of the determinants of this relationship. This paper conducts such an analysis using farm-level yield data. Research design, data, and methodology - Farm-level yield data from Illinois and Kansas farm business management associations are used for to calculate the correlation between farm and county loss and the share of farm loss systemic with county loss, and also for the regression analysis. Results - Average share of farm loss systemic with the county loss lies between 42% and 68%. The correlation between farm and county yield/revenue deviation from expected value is statistically significant in all four models. The coefficient is positive, implying the higher the correlation, the larger the share of farm loss that is systemic with the county loss. Conclusions - The findings of this study are consistent with the existing literature which argues that county variability may not be closely associated with farm variability. The findings of this study thus raise questions about the efficacy of area yield and revenue insurance products in helping farmers manage their risk.

• 한국안전학회지
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• 제36권4호
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• pp.88-98
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• 2021

Korean industry has achieved dramatic growth in a short time through continuous technical innovations. However, safety consciousness and management have not kept pace with industry growth. The characteristics of industrial accidents in socio-technical systems have become so complicated that it has been challenging for safety professionals to implement effective preventive measures because it is difficult to determine what is happening in the complex workplace. Thus far, they have focused on technical improvements and the requirements of OSH regulations to avoid legal responsibility. Accordingly, this study has used the systemic analysis method to explain the emergence of something unexpected in complex and multi-layered business structures, which is usually related to the variabilities of humans and organizations. This study chose a shipyard where a few fatal accidents had occurred because the shipbuilding industry includes numerous variabilities, including obtaining orders, manpower supply, procurement, etc. Systemic analysis progressed using FRAM based on two accident cases related to the truss platform used in LNG vessels. The outcome shows that each function within the system has its variabilities and has become coupled or dependent on other functions, increasing the possibility of accidents. This analysis method can provide OSH professionals with practical techniques for explaining what is happening in a complex socio-technical system and how to take proper measures.