• Proceedings of the KSME Conference
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• 2003.11a
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• pp.1822-1827
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• 2003

End-milling have been used widely in industrial system because it is effective to a material manufacturing with various shape. Recently the end-milling processing is needed the high-precise technique with good surface roughness and rapid time in precision machine part and electronic part. The optimum surface roughness has an effect on end-milling condition such as, cutting direction, spindle speed, feed rate and depth of cut, etc. Therefore this study was carried out to presume for mutual relation of end-milling condition to get the optimum surface roughness by regression analysis. The results shown that coefficient of determination($R^{2}m$) of regression equation has a fine reliability over 80% and regression equation of surface rough is made by regression analysis.

• Proceedings of the Korea Society for Simulation Conference
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• 2005.05a
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• pp.154-159
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• 2005

In this paper, We used the microphone unlike existing urodynamic inspection which diagnoses the LUTS(lower urinary tract symptoms) and proposed sound measurement the method which the urination happens and apply at a blockade diagnosis. To analyze the blockade degree, We made the experiment set to modeling the Lower Urinry System of the human body and made the microphone of the stethoscope form for the measurement of the urinary sound which the urination happens. We used PC for the analysis of the urinary sound to be measured and implemented the analysis program to use the MATLAB. Hereafter, An analysis result usage, The Practical use will be possible as one of new inspection methods's.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.361-366
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• 2001

The purpose of installation of the brine heating system for LNG storage tank is the prevention of ground freezing. If the ground of LNG tank areas is frozen, it is caused by safety problems. The design of brine heating system for LNG storage tank which is constructing in our country is not well considered about domestic weather conditions and economical efficiency. Therefore, this paper reports on the study of the optimized temperature of inside pipes and cooling process through the transient analysis by using the existing brine heating system.

• 한국컴퓨터산업교육학회:학술대회논문집
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• 2003.11a
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• pp.59-64
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• 2003

Principal component analysis(PCA) and neural network(NN) are used in reducing external noise in magnetocadiography. The PCA technique turns out to be very effective in reducing pulse noise in some SQUID channels and the NN find noise component automatically. Some experimental results obtained from 61 channel MCG system are shown.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1977-1980
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• 2015

Objective: The Von Hippel-Lindau syndrome (VHLD), an inherited neoplastic syndrome predisposing to central nervous system hemangioblastoma (CNS), pheochromocytoma (PCC), renal cell carcinoma(RCC), retinal hemangioma (RA) and renal cysts, is caused by mutations or deletions of the VHL tumor-suppressor gene. To assess VHL genotype-phenotype correlations with function of pVHL a gene mutation analysis of members in a Chinese family with non-syndromic PCCs and individuals with apparently sporadic pheochromocytoma (ASP) was performed. Materials and Methods: DNA samples of 20 members from the Chinese family with non-syndromic PCCs and 41 patients with ASP were analyzed by polymerase chain reaction and direct sequencing, confirmed by Taqman probe. Results: Three novel mutations (H125P, 623(^TTTGTtG) and R120T) were identified in the Chinese family and in 3 among 41 ASP patients. The mutations were all located in exon 2 of VHL gene encoding ${\beta}$-domain of pVHL. The tumor type in H125P carriers and R120T carriers was VHL type 2C. And 623(^TTTGTtG) carriers presented VHL type 2B or type 2C. Conclusions: VHL gene abnormalities were identified in the Chinese family with non-syndromic PCCs and patients with APS, resulting in dysfunction of pVHL. H125P and R120T could be associated with VHL type 2C, while 623(^TTTGTtG) might be linked with VHL type 2B or type 2C. Not only is the genetic analysis helpful for early diagnosis and treatment of patients with VHLD, it is also benefitial for research intoVHLD pathogenesis.

• Nuclear Engineering and Technology
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• v.44 no.7
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• pp.735-744
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• 2012

In order to quantify the flow distribution characteristics of APR+ reactor, a test was performed on a test facility, ACOP ($\underline{A}$PR+ $\underline{C}$ore Flow & $\underline{P}$ressure Test Facility), having a length scale of 1/5 referring to the prototype plant. The major parameters are core inlet flow and outlet pressure distribution and sectional pressure drops along the major flow path inside reactor vessel. To preserve the flow characteristics of prototype plant, the test facility was designed based on a preservation of major flow path geometry. An Euler number is considered as primary dimensionless parameter, which is conserved with a 1/40.9 of Reynolds number scaling ratio. ACOP simplifies each fuel assembly into a hydraulic simulator having the same axial flow resistance and lateral cross flow characteristics. In order to supply boundary condition to estimate thermal margins of the reactor, the distribution of inlet core flow and core exit pressure were measured in each of 257 fuel assembly simulators. In total, 584 points of static pressure and differential pressures were measured with a limited number of differential pressure transmitters by developing a sequential operation system of valves. In the current study, reactor flow characteristics under the balanced four-cold leg flow conditions at each of the cold legs were quantified, which is a part of the test matrix composing the APR+ flow distribution test program. The final identification of the reactor flow distribution was obtained by ensemble averaging 15 independent test data. The details of the design of the test facility, experiment, and data analysis are included in the current paper.

• Microbiology and Biotechnology Letters
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• v.24 no.4
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• pp.472-477
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• 1996

Natural human epidermal growth factor (nhEGF) was purified from pregnant human urine by benzoic acid adsorption, DEAE-Sepharose ion exchange, and immunoaffinity chromatography. The purified nhEGF was further separated into four fractions using Bondapak C$_{18}$ HPLC system. Following characterization by Western blot analysis and double immu- nodiffusion, we found that each fraction corresponds to four derivatives of the nhEGF. For biological analysis of nhEGF, we optimized the labeling time and serum concentration for the incorporatioin of 5-bromo-2'-deoxy uridine (BrdU), a non-radioactive alternative for [$^{3}$H]-thymidine uptake, into NIH 3T3 cells. The DNA synthesis of NIH 3T3 cells was gradually increased at the nhEGF concentrations between 0.1 - 10 ng/ml in the Dulbecco's Modified Eagles Medium (DMEM) containing 0.2% Fetal calf serum (FCS). When we assayed the biological activity of four fractions, the activity of the second fraction was superior to that of the others. Based on the results from the HPLC analysis spiked with recombinant human epidermal growth factor (rhEGF) and amino acid sequencing, we concluded that the second fraction was nhEGF and the other three fractions were the derivatives of nhEGF. In addition, the proportion of nhEGF was approximately 46% is compared with that of the other three derivatives.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.293-297
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• 1996

For the representative beat calculation and efficient rhythm analysis new method, that is, QRS typification were proposed. A problem that were resulted from pattern classification based on binary logic could be solved out by the fuzzy clustering and classification nodes could be reduced by using the proposed new feature vector. The accurate representative beat could be obtained by excluding the ST-T segment that happened outlier through ST-T segment typification procedure.

• Journal of Korean Medical Ki-Gong Academy
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• v.15 no.1
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• pp.44-60
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• 2015

Objective : The purpose of this study is to investigate the effect of Su-Gi therapy for Bell's palsy by using DITI. Methods : We investigated 16 patients with Bell's palsy who had visited in the H Korean medicine hospital in Gyeonggi Province from December 27th, 2010 to April 8th, 2015. The Su-Gi therapy was done by 1 times daily. We evaluated the change of them by using Digital Infrared Thermographic Imaging and Yanagihara's unweighted grading system. Results : There aren't meaningful differences in values for the meridian points in pretest and posttest which were observed by DITI of abnormal side and normal side. There are meaningful differences in values, for abnormal side and normal side of the meridian points in pretest and posttest of DITI. It was of significance that pretest Y and average ΔT of each the meridian points in the type of hyperthermia but not in the type of hypothermia. In the Correlation analysis of values of pretest and posttest, chaotic aspects of body heat distribution in the pretest change as a relatively consistent aspects in the posttest. It wasn't of significance that Correlation Analysis of Ups and downs in temperature of TE17 and Recovery speed observed by ΔY. In simple regression analysis of posttest's Y-system values against absolute ΔT by subtracting ΔTE17 from ΔST6, we didn't predict in the pretest, but could predict significantly in the posttest(Regression coefficient : -2.11) In the regression analysis result of the meridian points' ||pretest ΔT|-|posttest ΔT||, 陽白(GB14) and 頰車(ST6) are of significance (Total R-Square=0.447). But we couldn't obtain final regression analysis model. Conclusions: These results suggest that Su-Gi therapy may be effective for Bell's palsy.

• Special Issue of the Society of Naval Architects of Korea
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• 2011.09a
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• pp.112-116
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• 2011

The noise analysis is usually carried out in the early structure design stage for the main areas in a vessel such as an accommodation, an engine room, HVAC System and etc. If the analysis results are higher than the noise limits based on guideline, appropriate countermeasures are established to reduce noise levels and applied to the vessel. But excessive noise induced the main or auxiliary equipment and high pressure steam system is very difficult to check in the initial design stage, and local noise problems frequently appear in actual vessels. This paper deals with excessive noise of the engine control room on LNG carrier. It includes the cause analysis of excessive noise, the countermeasure, and verification. Also, it proves suitability of the countermeasure through the on-board test.