• The Journal of Internal Korean Medicine
• /
• v.37 no.4
• /
• pp.591-600
• /
• 2016

Objective: This study aimed to examine the relaxation effects and underlying mechanisms of Cynomorii herba (CH) extract in isolated rabbit corpus cavernous tissues.Methods: We experimented with CH extract (0.01-3.0 mg/mL). Nω-nitro-L-arginine (L-NNA) was experimented before the CH extract to contracted strips induced by phenylephrine (PE, 1 μM)and compared with nonexperimented. In addition, we experimented with calcium chloride (Ca²⁺, 1 mM) after pretreatment of the CH extract in Ca²⁺-free Krebs-Ringer solution to contracted strips induced by PE. The cell viability and nitric oxide (NO) concentration of human umbilical vein endothelial cells (HUVECs) were measured by an methylthiazol-2-yl-2, 5-diphenyl tetrazoliumbromide (MTT) assay and Griess reagent system. The ratio of smooth muscles to collagen fibers, in addition to eNOS- and PDE-5-positive reactions, was examined by histochemical and immunohistochemical staining.Results: The CH extract significantly induced the relaxation of the cavernous strips, and the pretreatment with L-NNA inhibited CH extract-induced relaxation. The L-NNA pretreatment reduced the increased contraction induced by the addition of Ca²⁺in Ca²⁺-free solution. Furthermore, the NO concentration of the HUVECs increased. When the CH extract was applied to the corpus cavernosum of the penis (CCP) of Sprague Dawley rats, the ratio of smooth muscles to collagen fibers by PE and the formation of eNOS around the helicine artery increased. However, the CH extract treatment decreased PDE-5 positive reactions.Conclusions: These results show that the relaxation effects induced by the CH extract are associated with the suppression of the influx of extracellular Ca²⁺ via the production of NO and eNOS and inhibition of PDE-5.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.6
• /
• pp.2595-2618
• /
• 2018

In this paper, we investigate secure communication with the presence of multiple eavesdroppers (Eves) in a two-tier downlink dense heterogeneous network, wherein there is a macrocell base station (MBS) and multiple femtocell base stations (FBSs). Each base station (BS) has multiple users. And Eves attempt to wiretap a macrocell user (MU). To keep Eves ignorant of the confidential message, we propose a physical-layer security scheme based on cross-layer cooperation to exploit interference in the considered network. Under the constraints on the quality of service (QoS) of other legitimate users and transmit power, the secrecy rate of system can be maximized through jointly optimizing the beamforming vectors of MBS and cooperative FBSs. We explore the problem of maximizing secrecy rate in both non-colluding and colluding Eves scenarios, respectively. Firstly, in non-colluding Eves scenario, we approximate the original non-convex problem into a few semi-definite programs (SDPs) by employing the semi-definite relaxation (SDR) technique and conservative convex approximation under perfect channel state information (CSI) case. Furthermore, we extend the frame to imperfect CSI case and use the Lagrangian dual theory to cope with uncertain constraints on CSI. Secondly, in colluding Eves scenario, we transform the original problem into a two-tier optimization problem equivalently. Among them, the outer layer problem is a single variable optimization problem and can be solved by one-dimensional linear search. While the inner-layer optimization problem is transformed into a convex SDP problem with SDR technique and Charnes-Cooper transformation. In the perfect CSI case of both non-colluding and colluding Eves scenarios, we prove that the relaxation of SDR is tight and analyze the complexity of proposed algorithms. Finally, simulation results validate the effectiveness and robustness of proposed scheme.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.11 no.1
• /
• pp.314-319
• /
• 2010

This paper represents the results of study on Extra High Voltage Power Cable Connection System Development. The purpose is to evaluate structural safety by numerical analysis for the relaxation of electric field concentration and by structural analysis of Carrier Pipe for easy installation of High Insulating Rubber Sleeve in the field, which is core technique of connection system. According to the results, the thickness of Carrier Pipe needs at least 9mm by optimization analysis of deformation behavior and insulating design & relaxation of electric field concentration. The result of contraction behavior of the connection part can be demonstrated with the same result of electric field relaxation analysis at the boundary of the electrode inserted into the insulating rubber sleeve.

• International journal of advanced smart convergence
• /
• v.8 no.4
• /
• pp.82-92
• /
• 2019

The appropriate use of color and light can increase psychological stress or feelings of mental stability. As such, many people currently use color therapy, which provides relaxation and stability through color stimulation. Many people currently use color therapy, which provides relaxation and stability through color stimulation. The smartphone-based psychological color therapy system that is to be developed through the study is a method for relieving stress. This study examines a method of using smartphones to understand user's emotional information such as types of stress and to provide color therapy information regarding these emotions. The goal of this study is to use the user's smart phone to provide color therapy that employs the user's emotional information. The intelligent emotion system, which uses platforms such as mobile devices and the PC, was designed considering the user's context, and it provides the user with various data formats such as images, video, text, audio, to send results to the user. The system was developed in the form of a service-based mobile application. The study designed an emotional color therapy system that uses a smartphone to measure the user's stress and provides appropriate color therapy.

• Biomolecules & Therapeutics
• /
• v.3 no.1
• /
• pp.58-62
• /
• 1995

We investigated whether nitric oxide (NO) may serve a role in bladder function by immunohistochemical analysis of the distribution of intrinsic NADPH-diaphorase and functional study of isometric tension recordings via a photo-induced adequate nitric oxide (PIANO) generating system using rat bladder. Results suggest that a small number of NADPH-diaphorase-positive perikarya are present within the bladder wall and within adjacent small ganglia. Furthermore, NADPH-diaphorase-positive nerve fibers were observed in the adventitial and muscular layers, subjacent to the urothelium and perivascular fibers. Rat bladder strips precontracted with 3$\mu$M carbachol were reversibly relaxed upon NO generation by UV irradiation. PIANO-mediated relaxation was sensitive to oxygen free radicals. In addition, tissue cGMP levels were increased by the PIANO generating system and elevated cGMP levels were decreased by pretreatment of guanylate cyclase inhibitor, methylene blue. These results indicate that NO may serve a role in modulating bladder tone in the rat.

• Journal of Power System Engineering
• /
• v.2 no.3
• /
• pp.21-26
• /
• 1998

Numerical simulations for various fluid flows require enormous computing time during iterations. In order to solve this problem, several techniques have been proposed. A SOR method is one of the effective methods for solving elliptic equations. However, it is very difficult to find the optimum relaxation factor, the value of this factor for practical problems used to be estimated on the basis of expertise. In this paper, the implication of the relaxation factor are translated into fuzzy control rules on the basis of the expertise of numerical analysers, and fuzzy controller incorporated into a numerical algorithm. From two cases of study, Poisson equation and cavity flow problem, we confirmed the possibility of computational acceleration with fuzzy logic and qualitative reasoning in numerical simulations. Numerical experiments with the fuzzy controller resulted in generating a good performance.

• Journal of Power System Engineering
• /
• v.11 no.2
• /
• pp.32-37
• /
• 2007

The present study describes the effects of music and vibroacoustic stimuli to the relaxation of human body. We have carried out the experiment on 6 human subjects of which are composed 3 men and 3 women. We have investigated the electroencephalogram(EEG) of all subjects before and after the stimuli of which are made a strong noise or the meditatiom music and the acoustic vibration. The vibroacoustic device has transmitted meditation music as vibration between 20Hz and 250Hz to the body. From the experimental results, we made sure the effects that the meditation music and vibroacoustic stimuli influenced the stress reduction of human body for good as alpha wave was increased continuously during the good stimuli and after that.

• Journal of Nutrition and Health
• /
• v.30 no.3
• /
• pp.244-251
• /
• 1997

The effects of Artemisia princeps var orientalis(mugwort), Circium japonicum var ussuriense (Unggungqui) on cadiovascular system in hyperlipidemic rats were investgated. Thirty rats devided into 5 experimental groups, were fed with the diet contained 1% chlesterol, 0.25% sodium cholate, 10% coconut oil and 5% lard by the same method of previous paper1). Contractile and relaxation responses in the isolated artria and thoracic aortae were measured and the morphological changes of the aortic endotherium from the rats were inspected. The responses of the right atrial to isoproterenol were significantly lower value in Ungungqui powder diet group(UP) and mugwort powder diet group(MP) than the control. The contraction force by injectin of phenylephrine and calcium in isolated thoracic aortae was significantly low value in the UP and the MP groups compaired to the control. The relaxation rate by acetylcholine in isolated thoracic aortae represented significantly higher value in UP than control. The morphological changes of endothelial cell suface was smallest in UP and the damage of endothelium by retarded in MP. Although Ungungqui and mugwort extract diet groups(UE, ME) were advanced, those were less than control.

• Journal of Power System Engineering
• /
• v.3 no.3
• /
• pp.14-21
• /
• 1999

The wave nature of heat conduction has been developed in situations involving extreme thermal gradients, very short times, or temperatures near absolute zero. Under the excitation of a periodic surface heating in a finite medium, the hyperbolic and parabolic heat conduction equations and the damped wave equations in heat flux are presented for comparative analysis by using the Green's function with the integral transform technique. The Kummer transformation is also utilized to accelerate the rate of convergence of these solutions. On the other hand, the temperature distributions are obtained through integration of the energy conservation law with respect to time. For hyperbolic heat conduction, the heat flux distribution does not exist throughout all the region in a finite medium within the range of very short times(${\xi}<{\eta}_l$). It is shown that due to the thermal relaxation time, the hyperbolic heat conduction equation has thermal wave characteristics as the damped wave equation has wave nature.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 1999.03a
• /
• pp.147-152
• /
• 1999

We have measured viscoelastic properties of fabrics in thickness direction. We assume that Maxwell model is very useful in stress relaxation of viscoelastic theories and appropriate formulas for fabric are calculated. Measurement system constitute of high precession load cell, translator and laser displacement sensor for viscoelastic properties was designed and elastic coefficients and damping coefficients were measured for 10 fabric samples. Elastic coefficients measured were 19~25 kN/㎡ and Damping coefficients measured were 4.8~8.7 MN$.$s/㎡. We concluded that these coefficients are good related with FUKURAMI collected from KESF system