• Korean Journal of Oriental Medicine
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• v.8 no.1
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• pp.109-126
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• 2002

The herbal extract (YMT_02) is a modified herbal extracts from Yukmijihwangtang (YMJ) to promote memory-enhancing. The YMJ extracts has been widely used as an anti-aging herbal medicine for hundred years in Asian countries. The purpose of this study is to; 1) quantitatively evaluate the memory-enhancing effect of YMT_02 by hehavior task, 2) identify candidate genes responsible for enhancing memory by cDNA microarray and 3) assess the anti-oxidant effect of YMT_02 on PC12 cell. Memory retention abilities are addressed by passive avoidance task with Sprague-Dawley (SD) male rat. Before the training session, the rats are subdivided into four groups and administrated with YMT_02, Ginkgo biloba, Soya lecithin and normal saline for 10 days. The retention test was performed. 24 hours after the training session. The retention time of the YMT_02 group was significantly (p<0.05) delayed $({\sim}100%)$, whereas Ginkgo biloba and Soya lecithin treatment delayed 20% and 10% respectively. The hippocampi of YMT_02 and control group were dissected and mRNA was further purified. After synthesizing cDNA using oligo-dT primer, the cDNA were applied and mRNA was further purified. After synthesizing cDNA using oligo-dT primer, the cDNA were applied to Incyte rat GEMTM 2 cDNA microarray. The microarray results show that prealbumin(transthyretin), phosphotidy lethanolamine N-methyltransferase, and PEP-19 are expressed abundantly in the YMT_02 treated group. Especially, PEP-19 is a neuron-specific protein, which inhibits apoptotic processes in neuronal cell. On the other hand, transcripts of RAB15, glutamate receptor subunit 2 and CDK 108 are abundant in control group. Besides, neuronal genes involved in neuronal death or neurodegeneration such as neuronal-pentraxin and spectrin are abundantly expressed in control group. Additionally, the YMT_02 shows an anti oxidative effect in the PC12 cell. The list of differentially expressed genes may implicate further insight on the action and mechanism behind the memory-enhancing effect of herbal extracts YMT_02, for example, anti-apoptotic, anti-oxidative, and neuroprotective effects.

• The Journal of the Korea Contents Association
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• v.21 no.12
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• pp.322-330
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• 2021

In modern aquaculture, mass mortality is a very important issue that determines the success of aquaculture business. If a fish disease is not detected at an early stage in the farm, the disease spreads quickly because the farm is a closed environment. Therefore, early detection of diseases is crucial to prevent mass mortality of fish raised in farms. Recently deep learning-based automatic identification of fish diseases has been widely used, but there are many difficulties in identifying objects due to insufficient images of fish diseases. Therefore, this paper suggests a method to generate a large number of fish disease images by synthesizing normal images and disease images using SinGAN deep learning model in order to to solve the lack of fish disease images. We generate images from the three most frequently occurring Paralichthys Olivaceus diseases such as Scuticociliatida, Vibriosis, and Lymphocytosis and compare them with the original image. In this study, a total of 330 sheets of scutica disease, 110 sheets of vibrioemia, and 110 sheets of limphosis were made by synthesizing 10 disease patterns with 11 normal halibut images, and 1,320 images were produced by quadrupling the images.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.05a
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• pp.571-572
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• 2022

Recently, VR/AR(virtual reality/augmented reality) contents have actively increased, and various services related to VR/AR allow users to experience remote places. Also, Metaverse technologies based on VR/AR generally used to provide content in virtual spaces. In this paper, we present a technique for synthesizing virtual humans after capturing a 360-degree panorama of a remote environment, and analyze the remote environment to identify the location where it can be captured without error, and apply a method of synthesizing virtual humans. According to this paper, it is possible to provide various captured spaces such as industrial plants, medical facilities, and schools as remote communication media.

• Journal of Digital Convergence
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• v.20 no.3
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• pp.93-103
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• 2022

This study aims to explore the digital citizenship education of pre-service teachers through deriving the needs for digital citizenship of pre-service teachers and analyzing their perceptions. To this end, an online survey was conducted on pre-service teachers enrolled in a graduate school of education, and data from 245 respondents were collected and analyzed. The needs assessment was prioritized by synthesizing paired t-test, Borich needs assessment, and the locus for focus model. The results of the study were as follows; first, when synthesizing the analysis of needs, the priority of digital citizenship of pre-service teachers was 'self-protection'. Second, pre-service teachers were aware of the need for digital citizenship education and were willing to participate in it. They hoped that it would be taught in an extra-curricular program or teacher education courses. Based on the study results, the direction of education to strengthen the digital citizenship of pre-service teachers was discussed.

• Journal of Microbiology
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• v.41 no.3
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• pp.248-251
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• 2003

Glutathione (GSH) is an important factor in determining tolerance against oxidative stress in living organisms. It is synthesized in two sequential reactions catalyzed by ${\gamma}$-glutamylcysteine synthetase (GCS) and glutathione synthetase (GS) in the presence of ATP. In this work, the effects of three different oxidative stresses were examined on GSH content and GSH-related enzyme activities in the fission yeast Schizosaccharomyces pombe. GSH content in S. pombe was significantly enhanced by treatment with hydrogen peroxide, ${\beta}$-naphthoflavone (BNF) and tert-butylhydroquinone (BHQ). Simultaneously, they greatly induced GCS and GS activity. However, they did not have any effects on glutathione reductase activity. These results suggest that GCS and GS activities in S. pombe are up-regulated by oxidative stress.

• The Journal of the Acoustical Society of Korea
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• v.20 no.1E
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• pp.14-19
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• 2001

We have proposed BIST method and circuit for embedded 16M SDRAM with logic. It can test the AC parameter of embedded 16M SDRAM using the BIST circuit capable of detecting the address of a fail cell installed in an Merged Memory with Logic(MML). It generates the information of repair for redundancy circuit. The function and AC parameter of the embedded memory can also be tested using the proposed BIST method. It is possible to test the embedded SDRAM without external test pin. The total gate of the BIST circuit is approximately 4,500 in the case of synthesizing by 0.25μm cell library and is verified by Verilog simulation. The test time of each one AC parameter is about 200ms using 2Y-March 14n algorithm.

• Journal of Broadcast Engineering
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• v.2 no.2
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• pp.125-135
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• 1997

This paper is concerned with realistic mainpulation of content in video sequences. Manipulation of content in video sequences is one of the content-based functionalities for MPEG-4 Visual standard. We present an approach to synthesizing video sequences by using the intermediate outputs of three-dimensional (3D) motion and depth analysis. For concreteness, we focus on video showing 3D motion of an observer relative to a scene containing planar runways (or roads). We first present a simple runway (or road) model. Then, we describe a method of identifying the runway (or road) boundary in the image using the Point of Heading Direction (PHD) which is defined as the image of, the ray along which a camera moves. The 3D motion of the camera is obtained from one of the existing 3D analysis methods. Then, a video sequence containing a runway is manipulated by (i) coloring the scene part above a vanishing line, say blue, to show sky, (ii) filling in the occluded scene parts, and (iii) overlaying the identified runway edges and placing yellow disks in them, simulating lights. Experimental results for a real video sequence are presented.

• Journal of Information Display
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• v.9 no.3
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• pp.8-11
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• 2008

A novel non-alkoxide sol-gel process for synthesizing Ga-doped ZnO thin film on glass was derived for possible use as a transparent electrode in flat-panel displays, using zinc acetate dehydrate as the starting material. The structural and electrical properties of thin films have been characterized as functions of Ga addition and post-heat-treatments. Their carrier density, Hall mobility, and optical transmittance were measured and discussed herein to explain the characteristics of the sol-gel-derived Ga-doped ZnO thin film on glass.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.2
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• pp.125-130
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• 2004

This paper describes an approach for synthesizing a Fuzzy Logic Controller(FLC) that combines the benefits of fuzzy logic control and fuzzy logic gain scheduling for the F/A-18 aircraft. Specially, fuzzy rules are utilized on-line to determine the denoralization factor(Κ) of a feedback fuzzy controller based on the dynamic pressure(Q) indicateing the region of the flight envelop the aircraft is operating in. Simulation results demonstrate that the proposed FLC provides excellent compensation for time-varying and/or nonlinear characteristics of the aircraft, and that it also exhibits satisfactory robustness with noisy air data sensors.

• MALSORI
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• no.43
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• pp.73-88
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• 2002

In this paper, for natural facial synthesis, lip-synch algorithm based on key-frame method using RBF(radial bases function) is presented. For lips synthesizing, we make viseme range parameters from phoneme and its duration information that come out from the text-to-speech(TTS) system. And we extract viseme information from Av DB that coincides in each phoneme. We apply dominance function to reflect coarticulation phenomenon, and apply bilinear interpolation to reduce calculation time. At the next time lip-synch is performed by playing the synthesized images obtained by interpolation between each phonemes and the speech sound of TTS.