• 동의생리병리학회지
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• 제18권3호
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• pp.924-929
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• 2004

Pigmented villonodular synovitis is a rare proliferating process of the synovium, tendon sheaths and bursae usually affecting the bone and joints. The disease can be localized or diffuse. Patients with this condition typically present with symptoms of mild discomfort and associated swelling of the involved joint. However, the spectrum of presentations is broad. Diagnosis of Pigmented villonodular synovitis can be clinically difficult, and plain radiographs are usually nonspecific. Magnetic resonance imaging is a highly diagnostic modality in characterizing pigmented villonodular synovitis when it contains hemosiderin deposits exhibiting low signal intensity on all pulse sequences. Magnetic resonance imaging is recommended for accurate preoperative staging of the disease and for follow up after treatment. I report a case of pigmented nodular synovitis in the knee joint, with review of literatures.

• Clinics in Shoulder and Elbow
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• 제27권1호
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• pp.11-17
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• 2024

Background: Rotator cuff tears are often associated with synovitis, but the ability of noninvasive ultrasonography to predict the severity of synovitis remains unclear. We investigated whether ultrasound parameters, namely peak systolic velocity in the anterior humeral circumflex artery and Doppler activity in the glenohumeral joint and subacromial space, reflect synovitis severity. Methods: A total of 54 patients undergoing arthroscopic rotator cuff repair were selected. Doppler ultrasound was used to measure peak systolic velocity in the anterior humeral circumflex artery and Doppler activity in the glenohumeral joint and subacromial space, and these values were compared with the intraoperative synovitis score in univariate and multivariate analyses. Results: Univariate analyses revealed that tear size, peak systolic velocity in the anterior humeral circumflex artery, and Doppler activity in the glenohumeral joint were associated with synovitis in the glenohumeral joint (P=0.02, P<0.001, P=0.02, respectively). In the subacromial space, tear size, peak systolic velocity in the anterior humeral circumflex artery, and Doppler activity in the subacromial space were associated with synovitis severity (P=0.02, P<0.001, P=0.02, respectively). Multivariate analyses indicated that tear size and peak systolic velocity in the anterior humeral circumflex artery were independently associated with synovitis scores in both the glenohumeral joint and the subacromial space (all P<0.05). Conclusions: These findings demonstrate that tear size and peak systolic velocity in the anterior humeral circumflex artery, which can both be measured noninvasively, are useful indicators of synovitis severity.

• Investigative Magnetic Resonance Imaging
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• 제11권1호
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• pp.54-57
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• 2007

국소성 소결절성 활막염은 무릎관절에 발생하는 드문 양성종양으로, 색소 융모결절성 활막염과 감별이 필요하다. 저자들은 자기공명영상에서 경 (pedicle)을 가지며 특징적인 MR 영상소견을 보이고 병리조직학적으로 확진된, 무릎에서 발생한 국소성 소결절성 활막염 1예를 보고한다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권6호
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• pp.502-506
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• 2009

Villonodular synovitis, also called pigmented villonodular synovitis, is the benign lesion with the characteristic of locally aggressive proliferation of mononuclear histiocyte and giant cell. Typically it involves single joint, especially about 80% of disease occurs in the knee joint. Villonodular synovitis of the temporomandibular joint is very rare disease. Differential diagnosis includes synovial chondromatosis and tumors of the temporomandibular joint. Optimal treatment consists of complete excision of the mass and removal of the synovium including adjacent affected bony structures. This is a case report of villonodular synovitis developed in the temporomandibular joint.

• Clinics in Shoulder and Elbow
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• 제10권1호
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• pp.140-145
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• 2007

색소 융모 결절성 활막염은 양성 증식성 활막의 병변으로 관절이나 건초, 점액낭 등을 침범한다. 이는 주로 한 관절에 발생하며, 다 관절 침범은 1% 미만에서 보고되고 있다. 또 슬관절 및 수부에 주로 발생하며, 견관절에서 발생하는 경우는 드물다. 색소 융모 결절성 활막염의 치료에 대해서는 아직까지 논란이 많은 상태이나 일반적으로 활액막 전 절제술이 표준치료로 알려져 있다. 저자들은 양측 견관절에 동시에 발생한 색소 융모 결절성 활막염으로 내원한 환자에 대해서 관절경적 활액막 절제술을 시행하여 수술소견과 임상 경과에 대해 문헌고찰과 함께 보고하고자 한다.

• 대한관절경학회지
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• 제2권2호
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• pp.181-184
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• 1998

저자들은 생체 분해성 Meniscus Arrow$^{(R)}$를 이용한 반월상 연골 봉합술후에 발생한 비세균성 활액막염을 최초로 경험하였다. 따라서 향후 Meniscus Arrow$^{(R)}$를 이용한 반월상 연골 봉합술 후에 활액막염이 발생할 수 있음을 고려하여야 하며, 이 경우에서 활액막 절제술로 좋은 결과를 얻을 수 있었기에 문헌과 함께 보고하는 바이다.

• 대한세포병리학회지
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• 제10권2호
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• pp.191-195
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• 1999

Pigmented villonodular synovitis is a destructive, fibrohistiocytic proliferation producing innumerable villous and nodular synovial protrusions. Its common locations are knee, ankle, foot, and hip. Although histologic feature of this tumor is well known, there have been few reports on the fine needle aspiration cytology findings. We report the cytologic features of a biopsy-proven case oi pigmented villonodular synovitis. The patient was a 21-year-old male with a mass of the right knee for 2 years. On fine needle aspiration cytology, the aspirates was composed of abundant mononuclear histiocytic cells, singly and in clusters, multinucleated slant cells, and hemoslderin pigments.

• 대한족부족관절학회지
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• 제14권1호
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• pp.101-104
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• 2010

Pigmented villonodular synovitis (PVNS) is a rare proliferative disease affecting joint synovium, tendon sheaths, bursae. The usual treatment for PVNS is a surgical excision. If destructive joint lesions have occurred, complete resections must be performed followed by arthrodesis or arthroplasty. We report a case of a pigmented villonodular synovitis involving an ankle joint which was treated by total ankle replacement for recurrence after simple synovectomy.

• 대한바이러스학회지
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• 제30권3호
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• pp.179-187
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• 2000

The etiology of rheumatic arthritis (RA) is associated with a number of genetic and environmental factors, but is not definitively elucidated. Recently, more attention has been paid to the possibility of microbial etiology in the pathogenesis of RA, because many different infectious agents have been reported to precede the onset or exacerbation of RA. Adenovirus (ADV) may be one cause of persistent or recurrent inflammatory arthritis. Varicella zoster virus (VZV) arthritis is detected frequently in RA patients treated with low dose methotrexate. The demonstration of simultaneous presence of both viral agents of specific viral nucleic acid in synovial fluids from synovitis patients would provide more direct evidence for arthritis etiological relationship, but there are no confirmed results. Therefore, we studied the ability of adenovirus and VZV to establish coinfection and persistent infection in synovial fluid from synovitis patients. The presence of viral agents in the synovial fluid demonstrated by isolation of cell culture, enzyme immunoassay and nested-PCR. The synovial fluids were also investgated for the presence of viral nucleic acid by nested-PCR using specific primer. ADV produced 220 bp and VZV produced 447 bp by each nested-PCR with specific primers. We detected 4/6 cases (66.7%) with persistent infection of ADV and 5/6 cases (83.3%) of VZV with 13 synovial fluids (between 7 to 52 day intervals) from synovitis patients by monoclonal ErA and nested-PCR. 21/28 cases (75%) with coinfection of adenovirus and VZV with synovial fluids from synovitis patients by nested-PCR. ADV and VZV coinfection and persistent infection of synovial fluids may provide a chronic antigenic stimuli to the immune system therefore provoking a continuing inflammatory response and caused the possibility of synovitis and arthritis.

• Korean Journal of Acupuncture
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• 제38권4호
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• pp.317-323
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• 2021

The purpose of this study is to report a case diagnosed with cellulitis and ankle joint synovitis after acupuncture treatment. An 85-years old female suffering from low back pain was managed by acupuncture including BL60. After treatment, unintended ankle pain occurred. The pain was diagnosed with cellulitis and synovitis by MRI. The patient was transferred to the Western medical hospital, and ankle joint arthroscopic synovectomy was performed. It was difficult to find a clear relationship between acupuncture and ankle joint synovitis. But it would be reasonable to assume that cellulitis was associated with acupuncture needling and synovitis was followed. Serious adverse effects, such as septic arthritis, are rare, but need significant attention. For acupuncture treatment on the ankle, especially using BL60, the depth and manipulation should be carefully performed along with sterilization.