• Title/Summary/Keyword: Sweat Volume

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Economical Sweating Function in Africans: Quantitative Sudomotor Axon Reflex Test

  • Lee, Jeong-Beom;Bae, Jun-Sang;Choi, Jeong-Hwan;Ham, Joo-Hyun;Min, Young-Ki;Yang, Hun-Mo;Kazuhiro, Shimizu;Matsumoto, Takaaki
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.1
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    • pp.21-25
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    • 2004
  • People in tropics have the ability to tolerate heat by residential permanence in the tropics. Previously, we have shown that African and Thai subjects who lived for whole their lives in only their respective countries sweat less under hot conditions than South Koreans who also lived whole their lives in Korea. The difference in sweating responses was attributed to the dissimilar central and peripheral sweating mechanisms operating in people from both groups. In the present study, acetylcholine (ACh), the primary transmitter for the sudomotor functions, was iontophoretically administered to South Koreans and Africans to determine the characteristic sudorific responses of their acclimatized biologic make-up to their respective environments. Using quantitative sudomotor axon reflex test (QSART), direct (DIR) and axon reflex (AXR) responses were evaluated. The findings revealed that the sweat onset-time among South Koreans was 0.91 min earlier than among Africans (P<0.01). The axon reflex sweat volume of nicotine receptor activity AXR(1) and sweat volume of muscarinic receptor activity DIR(2) among South Koreans were 79% and 53% greater (P<0.01), respectively. These results indicate that the reduced thermal sweating among Africans is at least in part attributed to the diminished sensitivity of sweat glands to ACh.

Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans

  • Shin, Young Oh;Lee, Jeong-Beom;Kim, Jeong-Ho
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.5
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    • pp.499-505
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    • 2016
  • The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland output (ASGO), tympanic and skin temperatures ($T_{ty}$, $T_{sk}$), basal metabolic rate (BMR), and evaporative loss volume changes were measured. Tympanic and mean body temperature (${\bar{T}}_b$; calculated from $T_{ty}$, $T_{sk}$) were significantly lower after summer-SA than that of winter-SA. Sweat onset time was delayed during winter-SA compared to that after summer-SA. BMR, AXR(1), AXR(2), and DIR sweat rates, ASGD and ASGO, and evaporative loss volume were significantly diminished after winter-SA relative to after summer-SA. In conclusion, changes in sweating activity measured by QSART confirmed the involvement of the peripheral nervous system in variation of sudomotor activity in seasonal acclimation.

Heat Acclimatization in Hot Summer for Ten Weeks Suppress the Sensitivity of Sweating in Response to Iontophoretically-administered Acetylcholine

  • Lee, Jeong-Beom
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.6
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    • pp.349-355
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    • 2008
  • To determine the peripheral mechanisms involved in thermal sweating during the hot summers in July before acclimatization and after acclimatization in September, we evaluated the sweating response of healthy subjects (n=10) to acetylcholine (ACh), a primary neurotransmitter involved in peripheral sudomotor sensitivity. The quantitative sudomotor axon reflex test (QSART) measures sympathetic C fiber function after iontophoresed ACh evokes a measurable reliable sweat response. The QSART, at 2 mA for 5 min with 10% ACh, was applied to determine the directly activated (DIR) and axon reflex-mediated (AXR) sweating responses during ACh iontophoresis. The AXR sweat onset-time by the axon reflex was $1.50{\pm}0.32$ min and $1.84{\pm}0.46$ min before acclimatization in July and after acclimatization in September, respectively (p<0.01). The sweat volume of the AXR(l) [during 5 min 10% iontophoresis] by the axon reflex was $1.45{\pm}0.53\;mg/cm^2$ and $0.98{\pm}0.24\;mg/cm^2$ before acclimatization in July and after acclimatization in September, respectively (p<0.001). The sweat volume of the AXR(2) [during 5 min post-iontophoresis] by the axon reflex was $2.06{\pm}0.24\;mg/cm^2$ and $1.39{\pm}0.32\;mg/cm^2$ before and after acclimatization in July and September, respectively (p<0.001). The sweat volume of the DIR was $5.88{\pm}1.33\;mg/cm^2$ and $4.98{\pm}0.94\;mg/cm^2$ before and after acclimatization in July and September, respectively (p<0.01). These findings suggest that lower peripheral sudomotor responses of the ACh receptors are indicative of a blunted sympathetic nerve response to ACh during exposure to hot summer weather conditions.

Seasonal Acclimatization in Summer versus Winter to Changes in the Sweating Response during Passive Heating in Korean Young Adult Men

  • Lee, Jeong-Beom;Kim, Tae-Wook;Min, Young-Ki;Yang, Hun-Mo
    • The Korean Journal of Physiology and Pharmacology
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    • v.19 no.1
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    • pp.9-14
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    • 2015
  • We investigated the sweating response during passive heating (partial submersion up to the umbilical line in $42{\pm}0.5^{\circ}C$ water, 30 min) after summer and winter seasonal acclimatization (SA). Testing was performed in July during the summer, 2011 [summer-SA; temp, $25.6{\pm}1.8^{\circ}C;$ relative humidity (RH), $82.1{\pm}8.2%$] and in January during the winter, 2012 (winter-SA; temp, $-2.7{\pm}2.9^{\circ};$ RH, $65.0{\pm}13.1%$) in Cheonan ($126^{\circ}52^{\prime}N$, 33.38'E), Republic of Korea. All experiments were carried out in an automated climatic chamber (temp, $25.0{\pm}0.5^{\circ}C$: RH, $60.0{\pm}3.0%$). Fifteen healthy men (age, $23.4{\pm}2.5$ years; height, $175.0{\pm}5.9cm;$ weight, $65.3{\pm}6.1kg$) participated in the study. Local sweat onset time was delayed during winter-SA compared to that after summer-SA (p<0.001). Local sweat volume, whole body sweat volume, and evaporative loss volume decreased significantly after winter-SA compared to those after summer-SA (p<0.001). Changes in basal metabolic rate increased significantly after winter-SA (p<0.001), and tympanic temperature and mean body temperature were significantly lower after summer-SA (p<0.05). In conclusion, central sudomotor acitivity becomes sensitive to summer-SA and blunt to winter-SA in Rebubic of Korea. These results suggest that the body adjusts its temperature by economically controlling the sweating rate but does not lower the thermal dissipation rate through a more effective evaporation scheme after summer-SA than that after winter-SA.

Effect on the Human Thermoregulation of Wear Training in Air Condition (여름철 냉방 조건에서의 착의 훈련이 인체의 체온 조절 반응에 미치는 효과)

  • Kim, Mi-Kyung;Choi, Jeong-Wha;Yeom, Hee-gyong
    • Journal of the Korean Society of Clothing and Textiles
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    • v.19 no.3
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    • pp.504-515
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    • 1995
  • This study was performed to investigate that wear training using thermal insulation with clothes has the effect on the human thermoregulatory response, especially on the heat tolerance. Twelve men and women in twenties wert divided into the control group, the training groups and each group except the control group had participated in wear training. The heat tolerance was assessed in all subjects who had participated in the experiment carried out in hot environment(40$\pm$1$^{\circ}C$, 50$\pm$5%RH) by such parameters as rectal temperature, skin temperature, systolic blood pressure, diastolic blond pressure, plume rate, total sweat volume, local sweat volume, subjective sensation, and the differences of heat tolerance in each group were compared. The results were as follows: In hot environment(4$0^{\circ}C$) the changing width of rectal temperature was decreased in the control and the heavy clothing group. Forehead and abdomen temperature in hot environment were significantly decreased after the training. Sweat rate was higher after the training than before. In all experimental groups, systolic and diastolic blood pries.;uses in hot environment(4$0^{\circ}C$) were significantly decreased after the training.

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Long-Term Tropical Residency Diminishes Central Sudomotor Sensitivities in Male Subjects

  • Lee, Jeong-Beom;Bae, Jun-Sang;Shin, Young-Oh;Kang, Jong-Chul;Matsumoto, Takaaki;Toktasynovna, Aliopva Aziza;Kaimovich, Alipov Gabit;Kim, Wan-Jong;Min, Young-Ki;Yang, Hun-Mo
    • The Korean Journal of Physiology and Pharmacology
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    • v.11 no.6
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    • pp.233-237
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    • 2007
  • Tropical natives (TROP) are capable of tolerating tropical heat because of their long-term adaptation to tropical environments. When exposed to heat stress, these natives tend to respond with lower sweat output, which is generally thought to be the result of heat acclimatization. The main objective of this study was to clarify central mechanisms inherent to suppressed thermal sweating in tropical natives (Malaysians) by comparing their sweating responses to those of temperate native (TEMP) (Koreans). This experiment was conducted in a thermoneutral climatic chamber ($24{\pm}0.5^{\circ}C,\;40{\pm}3%$ relative humidity). Heat loads were applied to each subject by the immersion of their lower legs in a hot water bath ($43^{\circ}C$ for 30 min). Sweat onset-time and sweat volume were compared between TROP and TEMP. The sweat onset-times on four selected points on the body ranged from 10.25 to 13.47 min in TEMP subjects, and from 16.24 to 17.83 min in TROP subjects (p<0.001). The local sweat volumes at the same sites ranged from 4.30 to $9.74 mg/cm^2$ in TEMP subjects, and from between 1.80 to $4.40mg/cm^2$ in TROP subjects (p<0.001). These results demonstrated a significant difference between TROP and TEMP subjects with regard to the manner in which they regulate their body temperatures when exposed to heat loads, and verified that long-term thermal adaptation blunts sweating sensitivities.

A Study on the Association between Sasang Health Index and THI(Todai Health Index) Score by Sasang Constitutions (완실무병 지표들의 사상체질별 건강수준 연관성 연구;THI(Todai Health Index) 설문지를 중심으로)

  • Jang, Eun-Su;Kim, Ho-Seok;Yoo, Jong-Hyang;Baek, Young-Wha;Oh, Seung-Yun;Lee, Si-Woo
    • Journal of Sasang Constitutional Medicine
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    • v.20 no.2
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    • pp.43-52
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    • 2008
  • 1. Objectives This study aims to find out the factors that affect to healthy level according to Sasang Constitutions by comparing THI health state with Sasang Health Index. 2. Methods One hundred twenty one healthy students from Korean oriental medical colleges participated in this study. We used the Questionnaire for Sasang Constitution Classification II(QSCC II) and expert opinion to diagnose Sasang Constitution, and used Sasang Health Index and THI questionnaire to take health information about Sasang Constitution, from 121 people of Sasang Constitution Information Bank. 3. Results 1) The 'Good Sweat' in Taeumin health level was higher than others, especially in case of 'Refreshness after Sweat' and the 'Good Feces' also higher in case of 'Much Volume in Defecation' 'Regularity in Defecation' 'Refreshness after Evacuation'. 2) The 'Good Feces' in Soyangin health level was higher than others, especially in case of 'Thickness'. 3) The 'Good Digestion' in Soeumin health level was not significantly higher than others. 4) The better symptoms in 'Good Sweat', the better health in Taeumin. 4. Conclusions Sasang Constitution Health Level is significantly related with Sasang Health Index.

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A Study on the Physiological Responses and the Microclimate in Girdle (Girdle 착용이 인체생리반응과 의복기후에 미치는 영향)

  • Kim Hyun Sik;Choi Jeong Wha
    • Journal of the Korean Society of Clothing and Textiles
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    • v.11 no.2 s.24
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    • pp.57-67
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    • 1987
  • The purpose of this study was to confirm the effects of girdle on the physiological responses and the microclimate in summer. The measuring points were rectal temperature, skin temperature, pulse rate and sweat volume as physiological responses and the inside clothing temperature, relative humidity as microclimate when the subjects wore girdle (girdle A; polyurethan+nylon, girdle B; polyurethan+cotton) for the period of rest and exercise in climate chamber. The enviromental conditions were at $25^{\circ}C$ ($65{\pm}5\%$ RH) and $30^{\circ}C$ ($75{\pm}5\%$ RR). The results were as followings. 1. Mean skin temperature increased in girdle during the exercise at $30^{\circ}C$. 2. The pulse rate decreased in girdle during the rest at $25^{\circ}C$. In the case of girdle A, it was remarkably decreased. Rectal temperature increased in girdle A and B during the exercise at $25^{\circ}C$. But the kinds of girdle didn't affect the pulse rate and rectal temperature. 3. The total sweat volume in girdle was larger than in control. 4. The difference between skin temperature and inside clothing temperature of abdomen had a tendency to increase at all experiment condition. 5. The relative humidity of inside ($RH_1$) and outside ($RH_2$) of girdle increased in girdle during the rest at $25^{\circ}C$ and $30^{\circ}C$. And the relative humidity of wearing girdle B was hig-her than girdle A during the rest at $25^{\circ}C$ and $30^{\circ}C$. The $RH_1$ after stepping at $30^{\circ}C$ was the highest in girdle A and the lowest in control. From this point of view, we concluded that physiological responses and the microclimate were affected by wearing girdle. And mean skin temperature and relative humidity of inside clothing were affected by the materials of girdle.

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Reference ranges for autonomic function tests in healthy korean adults

  • Park, Kee Hong;Kim, Byoung Joon;Kang, Sa-Yoon;Oh, Sun-Young;Sohn, Eun Hee;Song, Kyeong-jin;Shin, Jin-Hong;Kang, Kyoung Hwa;Cho, Eun Bin;Jeong, Heejeong;Lee, Hyung;Kim, Hyun Ah;Kim, Rock Bum;Park, Ki-Jong
    • Annals of Clinical Neurophysiology
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    • v.21 no.2
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    • pp.87-93
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    • 2019
  • Background: The standardized autonomic function test has become widely available. However, there are no reference data for this test for the Korean population. This study explored reference data for sudomotor and cardiovagal function tests for the Korean population. Methods: The sweat volume by quantitative sudomotor axon reflex test, heart-rate response to deep breathing (HRdb), expiration:inspiration (E:I) ratio, and Valsalva ratio (VR) were measured in 297 healthy Korean volunteers aged from 20 to 69 years. Multivariate regression analysis was performed to evaluate the effects of age, sex, and body mass index on these variables. The 2.5th, 5th, 10th, 90th, 95th, and 97.5th percentile values were obtained for each investigation. Results: The sweat volume was higher in males than in females. The HRdb and E:I ratio were negatively correlated with age, and were higher in males than in females. The VR was negatively correlated with age, but it was not correlated with sex. Conclusions: This study has provided data on the reference ranges for sudomotor and cardiovagal function tests in healthy Korean adults.

A Study on Brassiere Wearing By Girls at adolescence (사춘기 소녀의 브래지어 착용실태에 관한 연구)

  • 이경화
    • Journal of the Korean Home Economics Association
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    • v.36 no.6
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    • pp.57-70
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    • 1998
  • For developing girls' brassiere, the survey on the actual wearing condition of brassiere for girls aged 9-15 if fulfilled. The findings of this study can be summarized as follows. 1) The starting age of the breast growth differs according to regions, schools, grades and body shape. Reason wearing brassiere is to sustain body shape. present brassiere type preferred most is tank-top. Motive wearing brassiere is based on the other's recommendation. Purchasing brassiere is performed largely by mother. 2) Few complaints appeared in the aspects of sewing, hook, loop, wire, wearing sense, touching sense, sweat absorption etc. Evaluation for the brassiere color and design is totally satisfied. When purchasing brassiere, beauty and color are important to all of girls. Yes or No of satisfaction for the wearing sense and comfort of brassiere is answered negatively. 3) Elementary school pupils preferred sport type, While middle school students showed an order as follows-wire

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