• Title/Summary/Keyword: Susceptibility effect

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A Study of Susceptibility Decomposition in MRI (자기 공명 영상 시스템에서 자화율 분해 영상법에 관한 연구)

  • 노용만;홍인기
    • Journal of Biomedical Engineering Research
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    • v.16 no.4
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    • pp.395-402
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    • 1995
  • The intravoxel spin phases in magnetic resonance imaging (MRI) usually vary due to susceptibility differences of materials to be imaged. The phase variation in the voxel results in a reduction of the signal intensity. This signal intensity reduction is known as the susceptibility effect in MRI and has been studied extensively. In this paper, a new spectral decomposition technique Is proposed and the signal change due to the susceptibility effect can be analyzed. A pulse sequence for the spectral decomposition of the susceptibility was developed and applied to susceptibility imaging of venous blood possessing paramagnetic properties. The computer simulations and their corresponding experimental results obtained using both a phantom and human volunteers are reported. Key words : susceptibility effect in MRI : spectral decomposition of susceptibility effect.

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Susceptibility Effects v.s Flow Effects in Functional MRI (뇌의 기능영상에 있어서 자화율효과와 혈류효과 연구)

  • Park, J.B.;Chung, S.C.;Park, S.H.;Ro, Y.M.;Cho, Z.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1993 no.11
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    • pp.23-26
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    • 1993
  • In MR functional imaging, it is shown that the signal change during photic activation is composed of two terms, i.e. the inflow effect and the susceptibility effect. Relatively the inflow effect affects the data obtained by CGE on the condition of short $T_E$(15ms) and large $\alpha$(90degree). The susceptibility effect, however, mainly contributes to the data on the condition of large $T_E$(35ms) and small $\alpha$(30degree). In this apper, we will discriminate the susceptibility effect for the intermingled data affected both flow effect and susceptibility effect. Finally susceptibility only functional imaging is proposed by using TRFGE.

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Reduction of Susceptibility Effect Using Frequency Modulation DANTE (주파수 변조 DANTE를 이용한 자화율 효과의 감소)

  • Chung, S.T.;Hong, I.K.;Kim, J.H.;Ro, Y.M.;Cho, Z.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1995 no.11
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    • pp.167-170
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    • 1995
  • An frequency modulated (FM) DANTE pulse sequence generates a quadratic phase toward the transverse of image by an FM RF pulse. In the image of a serious susceptibility effect, the phase due to the difference of the susceptibility in the pixel occurs susceptibility error which arise signal loss. But the signal loss due to the susceptibility effect in the pixel is reduced when the quadratic phase adds in the pixel. In this paper, we have generated a quadratic function toward the transverse (X-Y) using FM DANTE sequence and the susceptibility effect is reduced in the gradient echo (GE) imaging. Computer simulation and experimental results is obtained by using a whole-body KAIS 2.0T NMR system.

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SSFP Interferometry (SSFPI) Technique Applied to functional MRI - A Fast and Direct Measurement of Magnetic Susceptibility Effect (SSFPI 기법을 이용한 MR 뇌기능 영상 -고 속의 자화율 효과의 직접적인 측정)

  • 정준영
    • Journal of Biomedical Engineering Research
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    • v.17 no.4
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    • pp.525-534
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    • 1996
  • We have developed a fast steady state free precession interferometry (SSFPI) technique which is useful for the fMRl (functional Magnetic Resonance Imaging). As is known, SSFP sequence with a suitable adjustment of Vadient (readeut) allows us to measure precession angle 6 which in tw relates to the field inhomogeneity. Combining the two pulses (known as FID and Echo) in FADE (Fast Acquisition Double Echo) sequence, for example, one can obtain the interference term which is directly related to the precession angle It has been known that a fast high resolution magnetic field mapping is possible by use of the modified FADE sequence or SSFPI, and we have attempted to use the SSFPI technique for the susceptibility-induced fMRl. When the method is applied to the susceptibility effect based functional magnetic resonance imaging (fMRl), it was found that the direct susceptibility effect measurement was possible without perturbations such as the backgrounds and inflow effect. In this paper, simulation results and experimental results obtained with 2.0 Tesla MRI system are presented.

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Opposite Effect of Spermine on the Susceptibility of Native and Denatured Calf Thymus DNA to DNase 1. (Native 및 Denatured Calf Thymus DNA의 DNase 1 에 대한 Susceptibility에 미치는 Spermine의 영향)

  • Thong-Sung Ko;Joon Huh;Chun-Bae Lee;Moo- Kyeu Park
    • Journal of the Korean Chemical Society
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    • v.27 no.6
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    • pp.429-433
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    • 1983
  • Spermine has opposite effect on the susceptibility of native and denatured calf thymus DNA toward deoxyribonuclease Ⅰ (DNase I; deoxyribonucleate 5'-oligonucleotidohydrolase; EC 3.1.4.5; from bovine pancreas). It enhances the susceptibility of the native DNA, whereas depresses that of the denatured DNA. In the absence of spermine, the reactivity of the deoxyribonuclease is apparently insensitive to the conformational difference of the native and denatured DNA.

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THE APPLICATION OF ARTIFICIAL NEURAL NETWORKS TO LANDSLIDE SUSCEPTIBILITY MAPPING AT JANGHUNG, KOREA

  • LEE SARO;LEE MOUNG-JIN;WON JOONG-SUN
    • Proceedings of the KSRS Conference
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    • 2004.10a
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    • pp.294-297
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    • 2004
  • The purpose of this study was to develop landslide susceptibility analysis techniques using artificial neural networks and then to apply these to the selected study area of Janghung in Korea. We aimed to verify the effect of data selection on training sites. Landslide locations were identified from interpretation of satellite images and field survey data, and a spatial database of the topography, soil, forest, and land use was constructed. Thirteen landslide-related factors were extracted from the spatial database. Using these factors, landslide susceptibility was analyzed using an artificial neural network. The weights of each factor were determined by the back-propagation training method. Five different training datasets were applied to analyze and verify the effect of training. Then, the landslide susceptibility indices were calculated using the trained back-propagation weights and susceptibility maps were constructed from Geographic Information System (GIS) data for the five cases. The results of the landslide susceptibility maps were verified and compared using landslide location data. GIS data were used to efficiently analyze the large volume of data, and the artificial neural network proved to be an effective tool to analyze landslide susceptibility.

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Simultaneous Unwrapping Phase and Error Recovery from Inhomogeneity (SUPER) for Quantitative Susceptibility Mapping of the Human Brain

  • Yang, Young-Joong;Yoon, Jong-Hyun;Baek, Hyun-Man;Ahn, Chang-Beom
    • Investigative Magnetic Resonance Imaging
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    • v.22 no.1
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    • pp.37-49
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    • 2018
  • Purpose: The effect of global inhomogeneity on quantitative susceptibility mapping (QSM) was investigated. A technique referred to as Simultaneous Unwrapping Phase with Error Recovery from inhomogeneity (SUPER) is suggested as a preprocessing to QSM to remove global field inhomogeneity-induced phase by polynomial fitting. Materials and Methods: The effect of global inhomogeneity on QSM was investigated by numerical simulations. Three types of global inhomogeneity were added to the tissue susceptibility phase, and the root mean square error (RMSE) in the susceptibility map was evaluated. In-vivo QSM imaging with volunteers was carried out for 3.0T and 7.0T MRI systems to demonstrate the efficacy of the proposed method. Results: The SUPER technique removed harmonic and non-harmonic global phases. Previously only the harmonic phase was removed by the background phase removal method. The global phase contained a non-harmonic phase due to various experimental and physiological causes, which degraded a susceptibility map. The RMSE in the susceptibility map increased under the influence of global inhomogeneity; while the error was consistent, irrespective of the global inhomogeneity, if the inhomogeneity was corrected by the SUPER technique. In-vivo QSM imaging with volunteers at 3.0T and 7.0T MRI systems showed better definition in small vascular structures and reduced fluctuation and non-uniformity in the frontal lobes, where field inhomogeneity was more severe. Conclusion: Correcting global inhomogeneity using the SUPER technique is an effective way to obtain an accurate susceptibility map on QSM method. Since the susceptibility variations are small quantities in the brain tissue, correction of the inhomogeneity is an essential element for obtaining an accurate QSM.

Analysis of Inflow and Susceptibility Effects in fMRI Obtained by CGE and TRFGE Techniques (CGE와 TRFGE 기법으로 얻은 뇌기능 영상에서 혈류효과와 자화율 효과의 해석)

  • No, Yong-Man;Jeong, Sun-Cheol;Jo, Jang-Hui
    • Journal of Biomedical Engineering Research
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    • v.16 no.4
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    • pp.431-438
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    • 1995
  • Functional imaging based on the susceptibility only is achieved by separation of the susceptibility effect from the mixture of flow effect by use of a tailored RF pulse in conjunction with gradient echo sequence. Using the tailored RF pulse the susceptibility enhanced functional imaging appears to be explicitly related to the deoxygenation processes, while in the conventional gradient echo technique functional contrast on $T2^{*}$ effect images appear to be mixed with a significant fraction of blood flow (in- flow) signals of both arterial as well as venous bloods due to the nature of the fast sequence employed with the gradient echo technique. In this paper, using the tailored RF pulses, one can unambiguously separate the susceptibility and flow effects in functional imaging. Since the signal obtained can be made sufficiently high and represents oxygenation process more accurately, it seems possible to study quantitative oxygen metabolisms in brain function hitherto difficult to do with other gradient echo techniques.

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PROBABILISTIC LANDSLIDE SUSCEPTIBILITY AND FACTOR EFFECT ANALYSIS

  • LEE SARO;AB TALIB JASMI
    • Proceedings of the KSRS Conference
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    • 2004.10a
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    • pp.306-309
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    • 2004
  • The susceptibility of landslides and the effect of landslide-related factors at Penang in Malaysia using the Geographic Information System (GIS) and remote sensing data have been evaluated. Landslide locations were identified in the study area from interpretation of aerial photographs and from field surveys. Topographical and geological data and satellite images were collected, processed, and constructed into a spatial database using GIS and image processing. The factors chosen that influence landslide occurrence were: topographic slope, topographic aspect, topographic curvature and distance from drainage, all from the topographic database; lithology and distance from lineament, taken from the geologic database; land use from Landsat TM (Thermatic Mapper) satellite images; and the vegetation index value from SPOT HRV (High Resolution Visible) satellite images. Landslide hazardous areas were analysed and mapped using the landslide-occurrence factors employing the probability-frequency ratio method. To assess the effect of these factors, each factor was excluded from the analysis, and its effect verified using the landslide location data. As a result, land 'cover had relatively positive effects, and lithology had relatively negative effects on the landslide susceptibility maps in the study area. In addition, the landslide susceptibility maps using the all factors showed the relatively good results.

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Effect Mo Addition on Corrosion Property and Sulfide Stress Cracking Susceptibility of High Strength Low Alloy Steels

  • Lee, Woo Yong;Koh, Seong Ung;Kim, Kyoo Young
    • Corrosion Science and Technology
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    • v.4 no.2
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    • pp.39-44
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    • 2005
  • The purpose of this work is to understand the effect of Mo addition on SSC susceptibility of high strength low alloy steels in terms of microstructure and corrosion property. Materials used in this study are high strength low alloy (HSLA) steels with carbon content of 0.04wt% and Mo content varying from 0.1 to 0.3wt%. The corrosion property of steels was evaluated by immersion test in NACE-TM01-77 solution A and by analyzing the growth behavior of surface corrosion products. SSC resistance of steels was evaluated using constant load test. Electrochemical test was performed to investigate initial corrosion rate. Addition of Mo increased corrosion rate of steels by enhancing the porosity of surface corrosion products. However, corrosion rate was not directly related to SSC susceptibility of steels.