Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지

SSFP Interferometry (SSFPI) Technique Applied to functional MRI - A Fast and Direct Measurement of Magnetic Susceptibility Effect

SSFPI 기법을 이용한 MR 뇌기능 영상 -고 속의 자화율 효과의 직접적인 측정

  • 정준영 (한국과학기술원 정보 및 통신공학과, 대전대학교 컴퓨터공학과)
  • Published : 1996.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

We have developed a fast steady state free precession interferometry (SSFPI) technique which is useful for the fMRl (functional Magnetic Resonance Imaging). As is known, SSFP sequence with a suitable adjustment of Vadient (readeut) allows us to measure precession angle 6 which in tw relates to the field inhomogeneity. Combining the two pulses (known as FID and Echo) in FADE (Fast Acquisition Double Echo) sequence, for example, one can obtain the interference term which is directly related to the precession angle It has been known that a fast high resolution magnetic field mapping is possible by use of the modified FADE sequence or SSFPI, and we have attempted to use the SSFPI technique for the susceptibility-induced fMRl. When the method is applied to the susceptibility effect based functional magnetic resonance imaging (fMRl), it was found that the direct susceptibility effect measurement was possible without perturbations such as the backgrounds and inflow effect. In this paper, simulation results and experimental results obtained with 2.0 Tesla MRI system are presented.

Keywords

References

  1. Introduction to Modern Electromagnetics C.H.Durney;C.C.Johnson
  2. Engineering Electromagnetics W.H.Hayt
  3. MRM v.8 Fast SSFP Gradient Echo Sequence for Simultaneous Acquisitions of FID and Echo Signals S.Y.Lee;Z.H.Cho
  4. MRM v.16 Analysis of the Higher-Order Echoes in SSFP D.J.Kim;Z.H.Cho
  5. MRM v.16 Generalized MR Interferography J.Henning
  6. Magn.Reson.Med. v.4 Rapid Fourier Imaging Using Steady State Free Precession R.C.Hawkes;S.Patz
  7. Magn.Reson.Med. v.6 The Application of Steady-State Free Precission in Rapid 2DFT NMR Imaging: FAST and CE-FAST Sequences M.L.Gyngell
  8. Magn.Reson.Med. v.6 FADE-A New Fast Imaging Sequence T.W.Redpath;R.A.Jones
  9. IEEE Trans. on Med. Imaging v.6 Steady-State Magnetizations in Rapid NMR Imaging Using Small Flip Angles and Short Repetition Intervals K.Sekihara
  10. Proc., SMRM, 12th Annual Meeting v.1 Functional brain imaging using blood flow changes Z.H.Cho;Y.M.Ro;J.B.Park;S.C.Chung;S.H.Park
  11. Proc. Natl. Acad. Sci. (USA) v.89 Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation K.K.Kwong;J.W.Belliveau;D.A.Chesler;I.E.Goldberg;R.M.Weiskoff;B.P.Poncelet;D.N.Kennedy;B.E.Hoppel;M.S.Cohen;R.Turner;H.Cheng;T.J.Brady;B.R.Rosen
  12. Proc. Natl. Acad. Sci. (USA) v.89 Intrinsic signal changes accompanying sensory stimulation:functional brain mapping using MRI S.Ogawa;D.W.Tank;R.Menon;J.M.Ellerman;S.Kim;H.Merkle;K.Ugurbil
  13. Proc. SMR, Second Meeting v.2 NMR Functional Imaging Using Tailored RF Gradent Echo Sequence-A True Susceptibility Measurement Technique Z.H.Cho;Y.M.Ro;S.H.Park;S.C.Chung;R.Ong
  14. Biochim. Biophy.Acta. v.714 Oxygenation Dependence of the Transverse Relaxation Time of Water Protons in Whole Blood at High Field K.R.Thulborn;J.C.Waterton;Paul M. Mathews;George Radda
  15. Biochemistry(2nd ed.) L. Stryer
  16. MRM v.31 Intravascular Susceptibility Contrast Mechanisms in Tissues Richard P. Kennan;Jianhui Zhong;John C. Gore
  17. MRI v.3 Susceptibility Artefacts in NMR Imaging K.M.Ludeke;P.Roschmann;R. Tischler
  18. MRM v.30 Processing Strategies for Time-Course Data Sets in Functional MRI of the Human Brain Peter A. Bandettini;A. Jesmanowicz;Eric C. Wong;James S. Hyde
  19. MRM v.35 NMR Functional Imaging Using Tailored RF Gradient Echo Sequence-A True Susceptibility Measurement Technique Z.H.Cho;Y.M.Ro;S.H.Park;S.C.Chung