• Title/Summary/Keyword: Surveillance program

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Postoperative Radiotherapy Improves Survival in Gastric Signet-Ring Cell Carcinoma: a SEER Database Analysis

  • Wei, Feng;Lyu, Hongwei;Wang, Shuoer;Chu, Yan;Chen, Fengyuan
    • Journal of Gastric Cancer
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    • v.19 no.4
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    • pp.393-407
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    • 2019
  • Purpose: To identify the potential therapeutic role of postoperative radiotherapy (RT) in patients with locally advanced (stage II and stage III) gastric signet ring cell carcinoma (SRC). Materials and methods: Patients with locally advanced gastric SRC from the Surveillance, Epidemiology, and End Results program database between 2004 and 2012 were included in our study. Univariate and multivariate Cox proportional models were performed, and survival curves were generated to evaluate the prognostic effect of postoperative RT and surgery alone on SRC patients. Propensity score matching (PSM) was used to avoid selection bias among the study cohorts. Results: We found that patients with postoperative RT had better probability of survival compared with those who did not receive RT (overall survival [OS], P<0.001; cancer-specific survival [CSS], P<0.001). After PSM, analysis of both overall and CSS showed that patients who underwent postoperative RT had better prognosis than those receiving surgery alone in the matched cohort (OS, P=0.00079; CSS, P=0.0036). Multivariate Cox proportional model indicated that postoperative RT had better effect on prognosis compared with surgery alone with respect to both overall (hazard ratio [HR], 0.716; 95% confidence interval [95% CI], 0.590-0.87; P=0.001) and CSS (HR, 0.713; 95% CI, 0.570-0.890; P=0.003). Conclusions: Postoperative RT had better prognosis compared with surgery alone for both overall and CSS for patients with locally advanced gastric SRC.

Static and dynamic characterization of a flexible scaled joined-wing flight test demonstrator

  • Carregado, Jose;Warwick, Stephen;Richards, Jenner;Engelsen, Frode;Suleman, Afzal
    • Advances in aircraft and spacecraft science
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    • v.6 no.2
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    • pp.117-144
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    • 2019
  • High Altitude and Long Endurance (HALE) aircraft are capable of providing intelligence, surveillance and reconnaissance (ISR) capabilities over vast geographic areas when equipped with advanced sensor packages. As their use becomes more widespread, the demand for additional range, endurance and payload capability will increase and designers are exploring non-conventional configurations to meet the increasing demands. One such configuration is the joined-wing concept. A joined-wing aircraft is one that typically connects a front and aft wings in a diamond shaped planform. One such example is the Boeing SensorCraft configuration. While the joined-wing configuration offers potential benefits regarding aerodynamic efficiency, structural weight, and sensing capabilities, structural design requires careful consideration of elastic buckling resulting from the aft wing supporting, in compression, part of the forward wing structural loading. It has been shown already that this is a nonlinear phenomenon, involving geometric nonlinearities and follower forces that tend to flatten the entire configuration, leading to structural overload due to the loss of the aft wing's ability to support the forward wing load. Severe gusts are likely to be the critical design condition, with flight control system interaction in the form of Gust Load Alleviation (GLA) playing a key role in minimizing the structural loads. The University of Victoria Center for Aerospace Research (UVic-CfAR) has built a 3-meter span scaled and flexible wing UAV based on the Boeing SensorCraft design. The goal is to validate the nonlinear structural behavior in flight. The main objective of this research work is to perform Ground Vibration Tests (GVT) to characterize the dynamic properties of the scaled flight vehicle. Results from the experimental tests are used to characterize the modal dynamics of the aircraft, and to validate the numerical models. The GVT results are an important step towards a safe flight test program.

Epidemiological and Clinical Characteristics of Elderly Fall Patients Visit to the Emergency Department: A Comparison by Gender

  • Kim, Jun Kew;Kim, Sun Pyo;Kim, Sun Hyu;Cho, Gyu Chong;Kim, Min Joung;Lee, Ji Sook;Han, Chul
    • Journal of Trauma and Injury
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    • v.31 no.3
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    • pp.117-124
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    • 2018
  • Purpose: This study was to analyze clinical and epidemiological characteristics of elderly patients who were admitted to the emergency department (ED) due to falls by separating male and female. Methods: We retrospectively analyzed the fall patients aged 65 years or older from the data of the in-depth surveillance study of injured patients visit to the ED under the supervision of the Korea Centers for Disease Control and Prevention (KCDC) from 2011 to 2016 by separating male and female. Results: A total of 361,588 elderly fall patients were analyzed and, among them, 14,429 (37.3%) were males and 24,208 (62.7%) were females. Male and female showed similar frequency of damage happening season. However, they showed falling accident mostly on winter. The time of injury occurrence is mostly from 12:00 to 18:00 with 4,949 (34.3%) male and 8,564 (35.4%) female. Most falls occurred in daily activities, accounting for 7,614 (52.8%) in males and 14,957 (61.8%) in females, respectively. Unintentional damage accounted for the most part and 7,395 (51.2%) of male and 15,343 (63.4%) of female were injured indoors. Head and neck were the most common site of injuring, with 8,392 (58.2%) in males and 7,851 (32.4%) in females. According to ED examination outcomes, most of the patients were discharged, while the majority of the hospitalized patients were admitted to the general patient room. Conclusions: The elderly falls occurred mostly from 12:00 to 18:00, during winter and to elderly women. Also, they happened unintentionally indoors in everyday life, mostly. Proved clinical, epidemiological characteristics from this research will be used as useful indicator at validity research of development of prevent program of falling accident for elderly people.

KOMPSAT Imagery Application Status (다목적실용위성 영상자료 활용 현황)

  • Lee, Kwangjae;Kim, Younsoo;Chae, Taebyeong
    • Korean Journal of Remote Sensing
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    • v.34 no.6_3
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    • pp.1311-1317
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    • 2018
  • The ultimate goal of satellite development is to use information obtained from satellites. Therefore, national-levelsatellite development program should include not only hardware development, but also infrastructure establishment and application technology development for information utilization. Until now, Korea has developed various satellites and has been very useful in weather and maritime surveillance as well as various disasters. In particular, KOMPSAT (Korea Multi-purpose Satellite) images have been used extensively in agriculture, forestry and marine fields based on high spatial resolution, and has been widely used in research related to precision mapping and change detection. This special issue aims to introduce a variety of recent studies conducted using KOMPSAT optical and SAR (Synthetic Aperture Radar) images and to disseminate related satellite image application technologies to the public sector.

EA Study on Practical Engineering Education through the Design and Configure of Safe Running Type Drones (안전 주행형 무인기의 설계 및 제작을 통한 실천 공학 교육에 관한 연구)

  • Jo, Yeong-Myeong;Lee, Sang-Gwon;Chang, Eun-Young
    • Journal of Practical Engineering Education
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    • v.9 no.1
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    • pp.7-13
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    • 2017
  • This study will provide a practical plan of engineering education through the study of major activities connected with the production of works to accomplish the graduation conditions by completing the comprehensive design subject and the result of the performance. The designed subject is to measure the minimum safety distance during driving using the obstacle detection function of the ultrasonic sensor and to perform the avoidance algorithm based on the measurement value of the acceleration gyro sensor. It is proposed an access surveillance system that minimizes the damage of drones, surrounding objects, and people, and improves air mobility. Experimental results show that the obstacles around the drone are detected by five ultrasonic sensors and the difference of output value is applied to each motor of the drone and obstacle avoidance is confirmed. In addition, the content and level of the data for measuring the achievement of learning achievement in the engineering education certification program were used and the results were confirmed to be consistent with the description of the engineering problem level required for the graduates of 4-year engineering college.

A monitoring survey on antimicrobial resistance of bacterial isolates from companion dogs in Incheon (인천지역 반려견 유래 세균의 항생제 내성 모니터링 조사)

  • Kim, Kyung-Mi;Cho, Min-Haneng;Lee, Seung-Hwan;Kim, Kyung-Ho;Lee, Jung-Gu;Lee, Sung-Mo
    • Korean Journal of Veterinary Service
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    • v.42 no.2
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    • pp.53-60
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    • 2019
  • This study was performed to investigate antimicrobial resistance in bacterial isolates obtained from companion dogs in veterinary hospitals and an animal shelter in Incheon. Drug resistance was examined respectively with the isolates of Escherichia coli, Enterococcus faecalis, and Staphylococcus pseudintermedius. The prevalence of drug resistance was calculated for each bacterial species towards 163 E. coli isolates, 156 E. faecalis isolates, and 86 S. pseudintermedius isolates by using selected antimicrobials. E. coli isolates were highly resistant to ampicillin, ciprofloxacin and tetracycline (47.9%, 28.2% and 28.2%, respectively). E. faecalis isolates were highly resistant to quinupristin-dalfopristin, tetracycline, kanamycin, rifampicin (69.8%, 66.0%, 53.8% and 51.9%, respectively). Higher levels of resistance were detected for ampicillin, penicillin, tetracycline, erythromycin, trimethoprim/sulfamethoxazole, telithromycin in S. pseudintermedius isolates (83.7%~52.6%, respectively). Occurrence of methicillin-resistant S. pseudintermedius (MRSP) was confirmed by oxacillin disc diffusion method, resulted in 23.3% occurrence among the S. pseudintermedius isolates (20/86 strains). The occurrence ratio of multidrug-resistance in the isolates of E. coli, E. faecalis, and S. pseudintermedius was 34.5%, 56.9%, and 67.9%, respectively. In this study, higher levels of antimicrobial drug resistance were observed in bacterial isolates obtained from dogs in Incheon. A regular monitoring and surveillance program should be implemented to prevent the emergence and spread of the drug-resistant bacteria carried in companion dogs.

Association of tumor differentiation grade and survival of women with squamous cell carcinoma of the uterine cervix

  • Matsuo, Koji;Mandelbaum, Rachel S.;Machida, Hiroko;Purushotham, Sanjay;Grubbs, Brendan H.;Roman, Lynda D.;Wright, Jason D.
    • Journal of Gynecologic Oncology
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    • v.29 no.6
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    • pp.91.1-91.12
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    • 2018
  • Objective: To examine the association between tumor grade and survival for women with squamous cervical cancer. Methods: This retrospective observational study utilized the Surveillance, Epidemiology, and End Result program data between 1983 and 2013 to examine women with squamous cervical cancer with known tumor differentiation grade. Multivariable analyses were performed to assess independent associations between tumor differentiation grade and survival. Results: A total of 31,536 women were identified including 15,175 (48.1%) with grade 3 tumors, 14,084 (44.7%) with grade 2 neoplasms and 2,277 (7.2%) with grade 1 tumors. Higher tumor grade was significantly associated with older age, higher stage disease, larger tumor size, and lymph node metastasis (all, p<0.001). In a multivariable analysis, grade 2 tumors (adjusted-hazard ratio [HR]=1.21; p<0.001) and grade 3 tumors (adjusted-HR=1.45; p<0.001) were independently associated with decreased cause-specific survival (CSS) compared to grade 1 tumors. Among the 7,429 women with stage II-III disease who received radiotherapy without surgical treatment, grade 3 tumors were independently associated with decreased CSS compared to grade 2 tumors (adjusted-HR=1.16; p<0.001). Among 4,045 women with node-negative stage I disease and tumor size ${\leq}4cm$ who underwent surgical treatment without radiotherapy, grade 2 tumors (adjusted-HR=2.54; p=0.028) and grade 3 tumors (adjusted-HR=4.48; p<0.001) were independently associated with decreased CSS compared to grade 1 tumors. Conclusion: Our study suggests that tumor differentiation grade may be a prognostic factor in women with squamous cervical cancer, particularly in early-stage disease. Higher tumor grade was associated with poorer survival.

The Effects of Body Consciousness and Body Esteem on Interpersonal Competence among Dental Hygiene Students (일부 치위생과 학생들의 신체의식과 신체존중감이 대인관계유능성에 미치는 영향)

  • Lee, Ji-Young;Jeong, Mii-Kyoung
    • Journal of Korean Dental Hygiene Science
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    • v.3 no.2
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    • pp.67-77
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    • 2020
  • This study investigated the effects of body consciousness and body esteem on interpersonal competence. A structured questionnaire was distributed to 220 dental hygiene students during July 1-31, 2020. The findings show that the subjects scored means of 3.32±0.26, 3.33±0.53, and 3.49±0.45 out of 5 in body consciousness, body esteem, and interpersonal competence, respectively. There were negative correlations between body surveillance and body shame (r=-0.303, p<0.001), as well as between two subfactors of body consciousness. Body shame was positively correlated with subfactors of interpersonal competence such as relationship initiation (r=0.217, p<0.01), claim for displeasure (r=0.218, p<0.01), and conflict management (r=0.231, p<0.01). Under the category of body esteem, body function esteem had positive correlations with conflict management (r=0.293, p<0.01) and consideration for others (r=0.141, p<0.05). Body consciousness and body esteem had effects on interpersonal competence, with an explanatory power of 13.4%. Higher body consciousness (β=.16, p=0.016) and body esteem (β=.22, p=0.02) were associated with greater interpersonal competence. These findings demonstrate that college students' objectified body consciousness and body esteem have an impact on their interpersonal competence. This raises the need to develop and apply a program to help students have positive perceptions of their bodies and establish their own individuality and body images to enhance their interpersonal competence.

Machine learning based radar imaging algorithm for drone detection and classification (드론 탐지 및 분류를 위한 레이다 영상 기계학습 활용)

  • Moon, Min-Jung;Lee, Woo-Kyung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.25 no.5
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    • pp.619-627
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    • 2021
  • Recent advance in low cost and light-weight drones has extended their application areas in both military and private sectors. Accordingly surveillance program against unfriendly drones has become an important issue. Drone detection and classification technique has long been emphasized in order to prevent attacks or accidents by commercial drones in urban areas. Most commercial drones have small sizes and low reflection and hence typical sensors that use acoustic, infrared, or radar signals exhibit limited performances. Recently, artificial intelligence algorithm has been actively exploited to enhance radar image identification performance. In this paper, we adopt machined learning algorithm for high resolution radar imaging in drone detection and classification applications. For this purpose, simulation is carried out against commercial drone models and compared with experimental data obtained through high resolution radar field test.

Antimicrobial resistance and virulence factors in staphylococci isolated from canine otitis externa (개의 외이도에서 분리한 포도상구균의 항생제 내성 및 병독성 유전자)

  • Cho, Jae-Keun;Lee, Jung-Woo;Kim, Joung-Ok;Kim, Jeong-Mi
    • Korean Journal of Veterinary Service
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    • v.45 no.3
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    • pp.171-180
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    • 2022
  • The aim of this study was to investigate the prevalence of antimicrobial resistance and virulence factors in staphylococci isolated from canine otitis externa. A total 295 causative microorganisms were isolated. The most common isolated species were Staphylococcus (S) pseudintermedius (94 isolates) followed by Pseudomonas aeruginosa (60 isolates), S. schleiferi (25 isolates), Escherichia coli (23 isolates) and Proteus mirabilis (20 isolates). Staphylococci isolates were showed high resistance to penicillin (78.6%), erythromycin (55.9%), tetracycline (52.4%), clindamycin (51.7%) and ciprofloxacin (42.8%). Of the 145 staphylococci isolates, 49 (33.8%) methicillin-resistant staphylococci (MRS) were observed, distributed among S. pseudintermedius (n=34), S. schleiferi (n=6), S. epidermis (n=4), S. hominis (n=2), S. aureus, S. caprae and S. saprophyticus (n=1, respectively). Forty-three (87.8%) of 49 MRS and 10 (10.4%) of 96 methicillin-susceptibility staphylococci harbored mecA gene. About 80% of MRS were multidrug-resistant with resistance to at least one antibiotic in three or more antibiotic classes. Resistance genes blaZ (93/114, 81.5%), ermB (35/81, 43.2%), ermC (3/81, 3.7%), aacA-aphD (50/54, 92.5%), tetM (69/76, 90.7%) and tetK (6/76, 7.8%) were detected among resistant isolates. Virulence factors genes lukF and lukS were found in 100%(145/145) and 43.4%(63/145), respectively. Genes encoding ermA, eta, etb and tsst were not detected. To the best of our knowledge, this is the first study which investigated for the presence of genes encoding antimicrobial resistance and staphylococcal toxins in staphylococci isolated from canine otitis externa. A continuous monitoring and surveillance program to prevent antimicrobial resistance in companion animals is demanded.