• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.277.2-277.2
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• 2013

Petri dishes and glass slides have been widely used as general substrates for in vitro mammalian cell cultures due to their culture viability, optical transparency, experimental convenience, and relatively low cost. Despite the aforementioned benefit, however, the flat two-dimensional substrates exhibit limited capability in terms of realistically mimicking cellular polarization, intercellular interaction, and differentiation in the non-physiological culture environment. Here, we report a protocol of culturing embryonic rat hippocampal neurons on the electro-spun polymeric network and the results from examination of neuronal cell behavior and network formation on this culture platform. A combinatorial method of laser-scanning confocal fluorescence microscopy and live-cell imaging technique was employed to track axonal outgrowth and synaptic connectivity of the neuronal cells deposited on this model culture environment. The present microfiber-based scaffold supports the prolonged viability of three-dimensionally-formed neuronal networks and their microscopic geometric parameters (i.e., microfiber diameter) strongly influence the axonal outgrowth and synaptic connection pattern. These results implies that electro-spun fiber scaffolds with fine control over surface chemistry and nano/microscopic geometry may be used as an economic and general platform for three-dimensional mammalian culture systems, particularly, neuronal lineage and other network forming cell lines.

• 소성∙가공
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• 제25권6호
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• pp.379-389
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• 2016

As a stator for steam turbine diaphragm, hollow-type nozzle stator to substitute for conventional solid one is introduced in this study. This hollowed stator can be separated into two parts such as upper and lower plates with large and curved surface area. This study focuses on thick plate forming process for the upper plate of the hollow-partitioned nozzle stator. First, to reduce forming defects such as under-cut and localized thinning of the deformed plate, and to avoid tool interruption between forming punch and lower die, tool design including the position determination of forming surfaces is performed. Uni-axial tensile tests are carried out using SUS409L steel plate with initial thickness of 5.00mm, and plastic strain ratio (r-value) is also obtained. Due to the asymmetric curved configuration of the upper plate, it is hard to adopt a series of blank holder or draw-bead, so the initial plate during this thick plate forming experiences unstable and non-uniform contact. To easy this forming difficulty and find suitable tool geometry without sliding behavior of the workpiece in the die cavity, two geometric parameters with respect to each shoulder angle of the lower die and the upper punch are adopted. FE models with consideration of 21 combinations for the geometric parameters are built-up, and numerical simulations are performed. From the simulated and predicted results, it is shown that the geometric parameter combinations with ($30^{\circ}$, $90^{\circ}$) and ($45^{\circ}$, $90^{\circ}$) for the shoulder angle of the lower die and the upper punch are suitably applied to this upper plate forming of the hollow-partitioned nozzle stator used for the turbine diaphragm.

• 대한기계학회논문집A
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• 제38권2호
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• pp.185-192
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• 2014

유성기어의 설계는 모듈 등의 이산변수, 잇수 등의 정수 변수, 치폭, 종횡비 등의 연속 변수가 혼재된 복잡한 문제로 이를 해결하기 위해서는 최적 설계 기법이 적용되어야 한다. 본 연구에서는 유전 알고리즘(Genetic algorithm)을 이용한 최적 설계를 유성기어 설계에 적용하였다. 유성기어 설계시 기본이 되는 기어 잇수, 모듈, 압력각, 치폭 등과 같은 매크로 지오메트리(Macro-geometry)를 이용하여 이뿌리/치면 강도에 대한 강도 평가를 수행하였으며, 상용 프로그램과의 비교를 통해 검증하였다. 유전 알고리즘을 이용하여 기어의 체적을 최소화하기 위한 최적 설계를 수행하였으며, 이를 통하여 설계자는 초기 설계시 시행착오를 줄여 설계 시간을 단축시킬 수 있었다.

• 대한치과보존학회:학술대회논문집
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• 대한치과보존학회 2003년도 제120회 추계학술대회 제 5차 한ㆍ일 치과보존학회 공동학술대회
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• pp.547-547
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• 2003

The aim of this study was to compare the effects of three Ni-Ti instruments on leaning ability by evaluating the volumetric and morphological changes in the apical 6mm of the root canals before and after preparation, using three-dimensionally reconstructed root canals of extracted human teeth. Forty-five teeth were used in this study. They were opened the chambers and removed the all pulp remnants ultrasonically. Subsequently, the canal wall was coated with silver paste and prepared using ProTaper, ProFile and GT rotary files according to the manufacturers instructions. Before and after root canal preparation, all the specimens were scanned with micro computed tomography and examined the differences in dentine volume removed, canal straightening, the proportion of the unchanged area and canal transportation. Quantitative analysis revealed that instrumentation increased in canal volume ranging between 0.081 and $1.866{\;}\textrm{mm}^3$. On average, the large apical preparation produced by ProTaper demonstrated smaller proportions of unchanged surface areas compared to the two other instruments in small canals. But in large canals like maxillary central incisor, the preparation of ProTaper instruments was not enough. ProTaper instrument was tended to increase more in canal volume as compared with the other two instruments but unchanged area was no significant difference. These results showed that three instruments had similar preparation ability and micro computed tomography in combination with the coated wall of root canal using silver paste is a nondestructive and valuable tool to study root canal geometry and changes after preparations in detail.

• Restorative Dentistry and Endodontics
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• 제36권1호
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• pp.1-11
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• 2011

서론: 이 문헌의 목적은 Nickel-titanium (NiTi) 전동 파일의 기계적 형태적 양상과 이에 의한 임상적 연관성을 고찰하는 것이다. NiTi 전동 파일은 다양한 고유의 형태로 시장에 소개되었고 경쟁 상품에 비해서 근관 성형에 더 나은 능력을 가졌다고 주장하고 있다. 본론: 이 문헌에서는 NiTi 전동 파일의 형태(예. 팁, 테이퍼, helical angle 등)와 파일의 임상 적용 성과 사이의 가능한 상관관계를 다음과 같이 다룬다; - NiTi 전동 파일의 파절 양상 - 비활성 파일팁과 glide path - 파일 경사도와 임상 효과 - 파일 횡단면적과 임상 효과 - 열처리와 표면 특성 - Screw-in 효과와 치근 상아질의 유지 - Screw-in 효과를 줄이기 위한 고안 결론: 이상의 내용을 바탕으로, 임상가는 다양한 NiTi 전동 기구를 사용함에 있어 임상 상황에 적절한 장점을 고려하여 선택하고 사용할 수 있는 도움을 받을 수 있을 것이다.

• 폴리머
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• 제35권6호
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• pp.531-536
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• 2011

블록 공중합체/단일중합체 블렌드에서 단일중합체의 농도와 분자량 변화에 따른 단일중합체의 분포 경향을 알아 보았다. 중수소화 폴리(메틸 메타크릴레이트) 또는 폴리스티렌을 중수소화 폴리스티렌-폴리(메틸 메타크릴레이트) 이중 블록 공중합체에 20 wt%까지 혼입하였다. 시료들은 소각 X-선 산란, 중성자 반사율 및 투과 전자 현미경으로 조사하였다. 실리콘 웨이퍼에 스핀 코팅하여 얇은 필름 상으로 제조한 블록 공중합체는 기질 표면에 대해 평행하게 배향된 라멜라 모폴로지를 형성하였다. 블록 공중합체의 미세 도메인 구조는 단일중합체의 부가에 의해 상당히 교란되었다. 그 결과로 단일중합체의 농도가 15 wt% 이상인 경우에는 배열 질서도가 낮은 라멜라 모폴로지가 나타났다. 단일공중합체의 농도나 분자량이 증가하면 단일중합체가 미세 도메인을 불균일하게 팽윤시키면서 보다 많은 단일중합체가 미세 도메인의 중앙 부위로 이동하였다.

• Smart Structures and Systems
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• 제18권3호
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• pp.485-500
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• 2016

Stay cables in some cable-stayed bridges suffer large amplitude vibrations under the simultaneous occurrence of rain and wind. This phenomenon is called rain-wind-induced vibration (RWIV). The upper rivulet oscillating circumferentially on the inclined cable surface plays an important role in this phenomenon. However, its small size and high sensitivity to wind flow make measuring rivulet size and its movement challenging. Moreover, the distribution of the rivulet along the entire cable has not been measured. This paper applies the videogrammetric technique to measure the movement and geometry dimension of the upper rivulet along the entire cable during RWIV. A cable model is tested in an open-jet wind tunnel with artificial rain. RWIV is successfully reproduced. Only one digital video camera is employed and installed on the cable during the experiment. The camera records video clips of the upper rivulet and cable movements. The video clips are then transferred into a series of images, from which the positions of the cable and the upper rivulet at each time instant are identified by image processing. The thickness of the upper rivulet is also estimated. The oscillation amplitude, equilibrium position, and dominant frequency of the rivulet are presented. The relationship between cable and rivulet variations is also investigated. Results demonstrate that this non-contact, non-intrusive measurement method has good resolution and is cost effective.

• Nuclear Engineering and Technology
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• 제53권4호
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• pp.1289-1296
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• 2021

In this study, an electron-scattering device was fabricated to practically use the ultra-high dose rate electron beams for the FLASH preclinical research in Dongnam Institute of Radiological and Medical Sciences. The Dongnam Institute of Radiological and Medical Sciences has been involved in the investigation of linear accelerators for preclinical research and has recently implemented FLASH electron beams. To determine the geometry of the scattering device for the FLASH preclinical research with a 6-MeV linear accelerator, the Monte Carlo N-particle transport code was exploited. By employing the fabricated scattering device, the off-axis and depth dose distributions were measured with radiochromic films. The generated mean energy of electron beams via the scattering device was 4.3 MeV, and the symmetry and flatness of the off-axis dose distribution were 0.11% and 2.33%, respectively. Finally, the doses per pulse were obtained as a function of the source to surface distance (SSD); the measured dose per pulse varied from 4.0 to 0.2 Gy/pulse at an SSD range of 20-90 cm. At an SSD of 30 cm with a 100-Hz repetition rate, the dose rate was 180 Gy/s, which is sufficient for the preclinical FLASH studies.

• Nuclear Engineering and Technology
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• 제52권12호
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• pp.2949-2957
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• 2020

Fatigue crack growth model has been developed for dissimilar metal weld joints of a piping component under cyclic loading, where in the crack is located at the center of the weld in the circumferential direction. The fracture parameter, Stress Intensity Factor (SIF) has been computed by using principle of superposition as K_H + K_M. K_H is evaluated by assuming that, the complete specimen is made of the material containing the notch location. In second stage, the stress field ahead of the crack tip, accounting for the strength mismatch, the applied load and geometry has been characterized to evaluate SIF (K_M). For each incremental crack depth, stress field ahead of the crack tip has been quantified by using J-integral (elastic), mismatch ratio, plastic interaction factor and stress parallel to the crack surface. The associated constants for evaluation of K_M have been computed by using the quantified stress field with respect to the distance from the crack tip. Net SIF (K_H + K_M) computed, has been used for the crack growth analysis and remaining life prediction by Paris crack growth model. To validate the model, SIF and remaining life has been predicted for a pipe made up of (i) SA312 Type 304LN austenitic stainless steel and SA508 Gr. 3 Cl. 1. Low alloy carbon steel (ii) welded SA312 Type 304LN austenitic stainless-steel pipe. From the studies, it is observed that the model could predict the remaining life of DMWJ piping components with a maximum difference of 15% compared to experimental observations.

• 대한조선학회논문집
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• 제56권1호
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• pp.11-22
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• 2019

In this paper, a Rankine source method is applied and validated to analyze the hydrodynamic response of a three-dimensional floating structure in the frequency domain. The boundary value problems for radiation and diffraction problem are solved by using a desingularized indirect boundary integral equation method (DIBIEM). The DIBIEM is simpler and faster than conventional methods based on the numerical surface integration of Green's function because the singularities of Green's function are located outside of fluid regions. In case of floating structure with complex geometry, it is difficult to desingularize the singularities of Green's function consistently. Therefore a mixed approach is carried out in this study. The mixed approach is partially desingularized except singularities of the body. Wave drift loads are calculated by the middle-field formulation method that is mathematically simple and has fast convergence. In order to validate the accuracy of the developed program, various numerical simulations are carried out and these results are analyzed and compared with previously published calculations and experiments.