• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.439-447
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• 2019

In this study, experiments were conducted to establish appropriate measures for slopes with high risk of collapse and to obtain results for minimizing slope collapse damage by detecting the micro-displacement of soil in advance by installing a laser sensor and a vibration sensor in the landslide reduction model experiment. Also, the behavior characteristics of the soil layer due to rainfall and moisture ratio changes such as pore water pressure and moisture were analyzed through a landslide reduction model experiment. The artificial slope was created using granite weathering soil, and the resulting water ratio(water pressure, water) changes were measured at different rainfall conditions of 200mm/hr and 400mm/hr. Laser sensors and vibration sensors were applied to analyze the surface displacement, and the displacement time were compared with each other by video analysis. Experiments have shown that higher rainfall intensity takes shorter time to reach the limit, and increase in the pore water pressure takes shorter time as well. Although the landslide model test does not fully reflect the site conditions, measurements of the time of detection of displacement generation using vibration sensors show that the timing of collapse is faster than the method using laser sensors. If ground displacement measurements using sensors are continuously carried out in preparation for landslides, it is considered highly likely to be utilized as basic data for predicting slope collapse, reducing damage, and activating the measurement industry.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.12 no.4
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• pp.413-418
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• 2019

Studies are now actively underway to confirm the degree of treatment and rehabilitation of patients with brain-related diseases (dementia, schizophrenia, depression, Parkinson's disease). Among them, Transcranial magnetic stimulation (TMS) is widely used in treatment because it is a technique that is used for noninvasive brain neuron control in patients with brain disorders. It can be seen that muscle fatigue of normal people increases during Transcranial magnetic stimulation. Therefore, in this paper, our purpose is to build an EMG measurement system to measure motor neuron-induced response during transcranial magnetic stimulation and We identify a motor-neutral response system using tendency in the RMS graph. As an experimental method, the Raw Data received through the surface EMG device and analyzed by RMS technique, after the contraction and relaxation movement of the biceps brachii. As a result of the experiment, we confirmed the trend of rising RMS graph, and it will can be used to determine the self-stimulation intensity for each individual in consideration of the data of the motor-neutral response.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.1-6
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• 2019

Organic dye-doped silica nanoparticles are used as a promising nanomaterials for bio-labeling, bio-imaging and bio-sensing. Fluorescent silica nanoparticles(NPs) have been synthesized by the modified $St{\ddot{o}}ber$ method. In this study, dye-free fluorescent silica NPs of various sized were synthesized by Sol-Gel process as the modified $St{\ddot{o}}ber$ method. The functional material of APTES((3-aminopropyl)triethoxysilane) was added as an additive during the Sol-Gel process. The as-synthesized silica NPs were calcined at $400^{\circ}C$ for 2 hours. The surface morphology and particle size of the as-synthesized silica NPs were characterized by field-emission scanning electron microscopy. The fluorescent characteristics of the as-synthesized silica NPs was confirmed by UV lamp irradiation of 365 nm wavelength. The photoluminescence (PL) of the as-synthesized silica NPs with different size was analyzed by fluorometry. As the results, the as-synthesized silica NPs exhibits same blue fluorescent characteristics for different NPs size. Especially, as increased of the silica NPs size, the intensity of PL was decreased. The blue fluorescence of dye-free silica NPs was attributed to linkage of $NH_2$ groups of the APTES layer and oxygen-related defects in the silica matrix skeleton.

• The Journal of Engineering Geology
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• v.29 no.1
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• pp.13-21
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• 2019

The rainfall intensity-duration curve (I-D curve) was used for selecting the dredging time of sediments behind a debris barrier which is located at the study area in Inje-gun, Kangwon Province. The I-D curve was newly suggested by using the data of rainfall-induced landslides for about 30 years from June to September in Kangwon Province. According to the monitoring results, the landslides have been not occurred during the monitoring period of the dredged sediments management system at the study area, and also all of the rainfall events were located below the I-D curve. The weight of the dredged sediments measured at the management system in the field was increased but the weight increment was small. It means that the increase of the dredged sediments was not the effect of landslide but the effect of soil erosion at the ground surface due to heavy rainfall. The weight of the dredged sediments behind a debris barrier could be known in real time using the rainfall data measured at the management system. Also, when the I-D curve is used with the management system, it is possible to select the optimum dredging time for sediments behind debris barrier.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.31 no.2
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• pp.62-72
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• 2019

Due to the difficulties in forecasting the intensity and the source location of tsunami the countermeasures prepared based on the deterministic approach fail to work properly. Thus, there is an increasing demand of the tsunami hazard analyses that consider the uncertainties of tsunami behavior in probabilistic approach. In this paper a fundamental study is conducted to perform the probabilistic tsunami hazard analysis (PTHA) for the tsunamis that caused the disaster to the east coast of Korea. A logic tree approach is employed to consider the uncertainties of the initial free surface displacement and the tsunami height distribution along the coast. The branches of the logic tree are constructed by reflecting characteristics of tsunamis that have attacked the east coast of Korea. The computational time is nonlinearly increasing if the number of branches increases in the process of extracting the fractile curves. Thus, an improved method valid even for the case of a huge number of branches is proposed to save the computational time. The performance of the discrete weight distribution method proposed first in this study is compared with those of the conventional sorting method and the Monte Carlo method. The present method is comparable to the conventional methods in its accuracy, and is efficient in the sense of computational time when compared with the conventional sorting method. The Monte Carlo method, however, is more efficient than the other two methods if the number of branches and the number of fault segments increase significantly.

• Journal of the Korean Geosynthetics Society
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• v.18 no.1
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• pp.67-77
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• 2019

The grouting method is utilized to reinforce and waterproof poor grounds, enhance the bearing capacity of structures damaged resulting from settlement due to elevation and vibration or differential settlement, and for cutoff. The purpose of this research is to enhance the compressive strength of grout materials by using aramid fiber and develop a high-strength ground improvement method by using blast furnace slag powder. In this regard, this study has conducted a uniaxial compression test after checking the high charge (higher than 50%) of the ratio of blast furnace slag powder and cement at 100:0, 70:30 and 40:60%, adding the aramid mixture based on 0, 0.5 and 1.0% of the cement and furnace slag powder weight and creating sand gels based on surface oiling rate of 0.7 and 1.2%. For the environmental review evaluation, a heavy metal exudation test and a pH test measurement have been conducted. The experiment results showed that 1% increase of aramid fiber led to 1.3 times greater uniaxial compression intensity. As for the hexavalent chrome, a 30% increase in blast furnace slag powder led to approximately 50% decrease in heavy metal exudation. However, the pH test revealed that a 30% increase in blast furnace slag powder resulted in approximately 0.5 increase in pH. Further research on the pH part is needed in the future.

• Journal of Gastric Cancer
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• v.21 no.2
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• pp.191-202
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• 2021

Purpose: A near-infrared (NIR) fluorescence imaging is a promising tool for cancer-specific image guided surgery. Human epidermal receptor 2 (HER2) is one of the candidate markers for gastric cancer. In this study, we aimed to synthesize HER2-specific NIR fluorescence probes and evaluate their applicability in cancer-specific image-guided surgeries using an animal model. Materials and Methods: An NIR dye emitting light at 800 nm (IRDye800CW; Li-COR) was conjugated to trastuzumab and an HER2-specific affibody using a click mechanism. HER2 affinity was assessed using surface plasmon resonance. Gastric cancer cell lines (NCI-N87 and SNU-601) were subcutaneously implanted into female BALB/c nu (6-8 weeks old) mice. After intravenous injection of the probes, biodistribution and fluorescence signal intensity were measured using Lumina II (Perkin Elmer) and a laparoscopic NIR camera (InTheSmart). Results: Trastuzumab-IRDye800CW exhibited high affinity for HER2 (K_D=2.093(3) pM). Fluorescence signals in the liver and spleen were the highest at 24 hours post injection, while the signal in HER2-positive tumor cells increased until 72 hours, as assessed using the Lumina II system. The signal corresponding to the tumor was visually identified and clearly differentiated from the liver after 72 hours using a laparoscopic NIR camera. Affibody-IRDye800CW also exhibited high affinity for HER2 (K_D=4.71 nM); however, the signal was not identified in the tumor, probably owing to rapid renal clearance. Conclusions: Trastuzumab-IRDye800CW may be used as a potential NIR probe that can be injected 2-3 days before surgery to obtain high HER2-specific signal and contrast. Affibody-based NIR probes may require modifications to enhance mobilization to the tumor site.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.33 no.4
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• pp.148-159
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• 2021

This study estimates the region of freshwater influence (ROFI) by Han River discharge in the Yeomha channel, Gyeonggi Bay. A 3-D numerical model, which is validated for reproducibility of variation in current velocity and salinity, is applied in Gyeonggi Bay. Distance of freshwater influence (DOFI) is defined as the distance from the entrance of Yeomha channel to the point where surface salinity is 28 psu. Model scenarios were constructed by dividing the Han River discharge into 10 categories (200~10,000 m³/s). The relation equation between freshwater discharge and DOFI was calculated based on performing a non-linear regression analysis. ROFI in Yeomha channel expands from the southern sea area of Ganghwa-do to the northern sea area of Yeongheung-do as the intensity of Han River discharge increases. The discharge and DOFI are a proportional relationship, and the increase rate of DOFI gradually decreases as discharge increases. Based on the relation equation calculated in this study, DOFI in the Yeomha channel can be estimated through the monthly mean Han River discharge. Accordingly, it will be possible to respond and predict problems related to damage to water quality and ecology due to rapid freshwater runoff.

• The Journal of Engineering Geology
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• v.32 no.2
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• pp.209-219
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• 2022

To experimentally investigate the variation of soil characteristics in slope during rainfall and the shape of slope failure, the model test was performed using soil box and artificial rainfall simulator. The model test of slope formed by the homogenous sand was performed, and the saturation pattern in the model slope due to rainfall infiltration was observed. The slope model with the inclination of 35° was set up on the slope of 30°, and the rainfall intensity of 50 mm/hr was applied in the test. The soil depth of 35 cm was selected by considering the size of soil box, and the TDR (time domain reflectometry) sensors were installed at various depths to investigate the change of soil characteristics with time. As the result of model test, the slope model during rainfall was saturated from the soil surface to the subsurface, and from the toe part to the crest part due to rainfall infiltration. That is, the toe part of slope was firstly saturated by rainfall infiltration, and then due to continuous rainfall the saturation range was enlarged from the toe part to the crest part in the slope model. The failure of slope model was started at the toe part of slope and then enlarged to the crest part, which is called as the retrogressive failure. At the end of slope failure, the collapsed area increased rapidly. Also, the mode of slope failure was rotational. Meanwhile, the slope failure was occurred when the matric suction in the slope was reached to the air entry value (AEV) estimated in soil-water characteristic curve (SWCC).

• Economic and Environmental Geology
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• v.55 no.3
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• pp.281-293
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• 2022

We examined degradation characteristics of lead based pigments(white lead, Red lead, Litharge) according to atmospheric environmet condition, for example atmospheric gas(CO₂, NO₂) and soluble salt. Painted samples not changed material compositions but were occured the color change(𝚫E 4~31) after exposed UV irradiation. All sample were not affected by CO₂ gas not only color but chemical composition. However, samples were remakably changed color exposed NO₂ gas and it was formed secondary product like as lead nitrate. Such as red lead and white lead samples' color difference were 𝚫E 2 and 𝚫 10 respectively and became dark, along with litharge became bright and color difference was 𝚫E 5 after react with NO₂ gas. It confirm that NO₂ was influential factor than CO₂ in the case of same concentration. Furthermore salt spray test was taken to figure out soluble salt influence in fine dust. The result showed noticeable color change and secondary product was formed on samples' surface. The glue film peeled off or hole, and color changed around the secondary products. After salt spray, XRD pattern showed decrease peak intensity and lower crystalinity. As a result of salt spray test, white lead was formed new product litharge and litharge was formed litharge and minium. According to the results, influential atmospheric factors for conservation of paint pigments were UV, NO₂, soluble salt, and litharge was most weakness throughout lead base pigments.