• 재활간호학회지
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• 제18권2호
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• pp.75-87
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• 2015

Purpose: The purpose of this study was to develop a home-based self-management support intervention (SMSI) for enhancing pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD) in Korea. Methods: This methodological study was conducted by following these 4 steps: constructing the preliminary draft of a home-based SMSI from existing recommendation and a literature review on PR and self-management interventions; testing content validity with 6 experts in COPD; exploring clinical applicability of the intervention by applying it to 4 COPD patients; determining the final intervention. Results: The final intervention included 4 components and contents identified from the literature review as essentials for self-management of COPD patients: education; exercise training and practice including breathing, muscle strengthening and aerobic exercises; cognitive behavioral strategies including informative self-decision making, collaborative goal setting and supportive advice; and action planning for exacerbation. The intervention was designed to be run by a trained nurse and had 8 weekly sessions consisting of three 60-minute face-to-face sessions and five 20-minute phone-call sessions. Conclusion: The intervention developed in this study incorporates essential components of self-management, i.e. action plan and cognitive behavioral strategies, and will contribute to enhancing and maintaining effects of PR by increasing self-management in COPD patients.

• Journal of Yeungnam Medical Science
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• 제32권1호
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• pp.47-49
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• 2015

Sorafenib is indicated for the treatment of advanced hepatocellular carcinoma (HCC), but although rare, tumor lysis syndrome (TLS) can be fatal in HCC patients with a large tumor burden. The authors describe the case of a 55-year-old hepatitis B carrier who visited our clinic with progressive dyspnea for 3 weeks. Chest and abdominal computed tomography revealed a huge HCC in the left lobe of the liver with invasion of the inferior vena cava, right atrium, and pulmonary arteries. After 8 days of sorafenib administration, TLS was diagnosed based on the characteristic findings of hyperuricemia, hyperkalemia, and acute kidney injury with massive tumor necrosis by follow-up imaging. Despite discontinuation of sorafenib and supportive care, the patient's clinical course rapidly deteriorated. The authors describe a rare but fatal complication that occurred soon after sorafenib initiation for HCC. Careful follow-up is required after commencing sorafenib therapy for the early diagnosis and management of TLS.

• 한국의사학회지
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• 제25권1호
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• pp.61-69
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• 2012

A growing number of people shows deep interests in healthcare and treatments for the elderly with increasing their population. Contrary to general adults, old people have their own physiological and pathological characteristics. Therefore, treatments for the elderly should be different form those for others in younger generation. Alimentotherapy, which means the treatment or prevention by means of food, is one of the best way to deal with geriatrics that are chronic, multiple. Korea has its tradition and plenty of information in this field. Even in the early ChoSun Dynasty, when people suffered from lack of proper medical care, physicians used dietary prescriptions as active treatments, Therefore, we can find lots of cases in "Hyangyak-jibseogbang" and "Euibangyoochui" which are medical books published at that time. After that, a specialized alimentotherapy book, "Sikryochanyo" was written based on that kind of total medical volumes. With development of society, economy. and medical science, alimentotherapy has grown remarkably. Unlike in the early Chosun Dynasty, it was used positively for promoting general health condition and practiced as supportive method for medication in the late Chosun Dynasty. Considering the characteristics of the elderly, alimentotherapy is the most effective way to keep them healthy and can also used with medication.

• 대한유전성대사질환학회지
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• 제14권1호
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• pp.29-36
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• 2014

Mucopolysaccharidoses (MPSs) are a group of rare inherited metabolic diseases caused by deficiency of lysosomal enzymes. MPSs are clinically heterogeneous and characterized by progressive deterioration in visceral, skeletal and neurological functions. The aim of this article is to review the treatment of MPSs, the unmet needs of current treatments and vision for the future including recent clinical trials. Until recently, supportive care was the only option available for the management of MPSs. Hematopoietic stem cell transplantation (HSCT), another potentially curative treatment, is not routinely advocated in clinical practice due to its high risk profile and lack of evidence for efficacy. From the early 2000s, enzyme replacement therapy (ERT) was approved and available for the treatment of MPS I, II and VI. ERT is effective for the treatment of many somatic symptoms, particularly walking ability and respiratory function, and remains the mainstay of MPS treatment. However, no benefit was found in the neurological symptoms because the enzymes do not readily cross the blood-brain barrier (BBB). In recent years, intrathecal (IT) ERT, substrate reduction therapy (SRT) and gene therapy have been rapidly gaining greater recognition as potential therapeutic avenues. Although still under investigation, IT ERT, SRT and gene therapy are promising MPS treatments that may prevent the neurodegeneration not improved by ERT.

• Neonatal Medicine
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• 제16권2호
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• pp.244-247
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• 2009

갑상선 반쪽 무형성증은 갑상선의 한쪽 엽이 형성되지 않는 드문 선천성 갑상선 질환이다. 갑상선 반쪽 무형성증 자체는 대개 아무런 임상 증상을 초래하지 않으므로 대부분은 동반된 갑상선 질환을 진단하는 과정이나 수술 중에 우연히 발견된다. 저자들은 선천성 갑상선기능저하증이 의심되어 내원한 1개월된 영아에서 원인을 찾던 중에 갑상선 초음파 및 스캔 검사를 통해 갑상선 반쪽 무형성증을 진단하였기에 보고하는 바이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권1호
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• pp.60-64
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• 2006

Backgrounds: Though they are considered as reliable devices, titanium plates and screws have limitations due to some potential problems. To overcome these problems, researches on bioabsorbable materials for internal fixation have been continuing. Recently, there are many clinical trials to apply biodegradable internal fixation devices in oral and maxillofacial surgery. The purpose of this study was to evaluate the clinical results of application of bioabsorbable plates and screws in orthognathic surgery. Methods: Fifty-four patients with dentofacial deformity (17 male patients and 37 female patients) were selected in this study. The patients were treated by internal fixation using bioabsorbable plates and 2.4-mm, 2.0-mm pretapped screws (Biosorb FX, Bionix Implants, Inc., Finland). The patients were evaluated for complications during the follow-up period. Results: Five patients (9.3%) experienced complications. All complications in these cases were infection. No other complications related with physical or mechanical properties of bioabsorbable plates were found such as malunion or nonunion, fractures of plates and loosening of screws. All complications were minor and adequately managed with drainage and supportive care with antibiotics coverage. Conclusions: From the results, the use of these fixation systems in orthognathic surgery will provide a promising alternative titanium fixation in appropriate cases.

• 대한임상독성학회지
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• 제13권1호
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• pp.33-35
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• 2015

A 24 year-old man attempted suicide by injection of 1 cc of thinner into his left antecubital vein; 3 hours later, he visited our emergency room because of left chest pain. We suspected a chemical pneumonitis based on the abnormal findings of his chest X-ray and computed tomography. On the 3rd day after admission, a cellulitis also occurred at the injection area. His symptoms were relieved after supportive care for 2 weeks. There is significant experience with intoxication of thinner inhalation, whereas intoxication of intravenous thinner is rare.

• 호스피스학술지
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• 제4권2호
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• pp.42-51
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nauseaㆍvomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city to receiving more than two Cisplatin combination chemotherapy. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were collected from February 1, 2000 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, X2-test, t-test, Repeated Measures ANOVA. Result: 1)The degree of nauseaㆍvomiting on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2)The degree of anorexia on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nauseaㆍvomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nauseaㆍvomiting and anorexia who are receiving chemotherapy.

• 기본간호학회지
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• 제11권3호
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• pp.281-291
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• 2004

Purpose: This study was done to investigate the effects of a rehabilitation program including Koryo Hand-Acupuncture on physical function, self-esteem, and quality of life of post-stroke elderly patients. Method: A nonequivalent control group pre-post test research design was used. Participants in the study were 44 post-stroke elderly people (22 in an experimental group, 22 in a control group) enrolled in a social welfare center and a hospital in K city. Data were collected from April 6 to August 20, 2004. The program consisted of Koryo Hand-Acupuncture, ROM exercise, health education and supportive care. The analyses were carried using frequencies, percentages, $x^2$-test, Fisher exact and t-test with SPSS 10.0. Results: The patients in the experimental group, who took part in the 10-weeks rehabilitation program including Koryo Hand-Acupuncture, had significant increases in shoulder joint flexion, shoulder joint abduction, elbow joint flexion, hip joint flexion, knee joint flexion, knee joint extension, flexibility, self-esteem and quality of life as compared to the control group. Conclusion: These results suggest that a rehabilitation program including Koryo Hand-Acupuncture may be utilized as an effective nursing program to improve physical function, self-esteem and quality of life for post-stroke elderly patients.

• 보건교육건강증진학회지
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• 제17권2호
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• pp.165-181
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• 2000

Even though enormous governmental expenses and scientists' efforts to find out definite causes and treatment methods of senile dementia have been investigated, little has been known in this area. Along with knowledge development of the etiology and treatment of the dementia, researchers have started to focus on improving the quality of life of the older adults with dementia through psychosocial intervention. This study was designed to propose a theoretical framework for establishing therapeutic environment for the older adults with dementia and for developing principles and strategies of caring. The results of this study were expected to help family members of the older adults with dementia to understand behavioral problems of the demented persons. The results can be utilized for health professionals to provide nursing interventions to reduce family caregivers' burden and to improve the quality of life of the older adults with dementia and their family. Caring principles developed from this study were as follows: 1. To minimize the stressors that can stimulate older adults with dementia. 2. To assess demented person's needs for safety and provide intervention based on the assessment. 3. To provide therapeutic environment for older adults with dementia to reduce confusion and to improve orientation. 4. To organize simple regular daily activities that older adults can anticipate. 5. To enhance demented person's self-esteem and self-confidence by providing supportive care. 6. To promote social interaction of the older adults with dementia by utilizing adequate activity programs.