• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.2
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• pp.134-140
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• 2018

Chylomicron retention disease, also known as Anderson's disease, is a rare hereditary hypocholesterolemic disorder, recessive inherited, characterized by nonspecific symptoms as abdominal distension, steatorrhea, and vomiting associated with failure to thrive. We describe a patient with failure to thrive, chronic diarrhea and steatorrhea who the diagnosis of chylomicron retention disease was established after several months of disease progression. The genetic study confirmed a homozygosity mutation in SAR1B gene, identifying a mutation never previous described [c.83_84delTG(p.Leu28Argfs*7)]. With this case report the authors aim to highlight for this very rare cause of failure to thrive and for the importance of an attempting diagnosis, in order to start adequate management with low fat diet supplemented with fat-soluble vitamins, reverting the state of malnutrition and avoiding possible irreversible and desvantating complications.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2005.11a
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• pp.171-175
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• 2005

The purpose of this study was to suggest the Support and Infill system for 126.6m$^2$-sized housing unit which meets residents' variety. The subjects were 100 housewives who lived in 126.6m$^2$-sized housing unit in the apartment complex, Busan. The data was collected by using model and questionnaire. The model was made to be same as the current 126.6m$^2$-sized floor plan. The residents preferred the flexible housing unit apartment complex. Also, the residents' needs for floor plan of housing unit were various. Therefore, the development of flexible housing unit is needed. On the basis of these findings, the support and infill system for 126.6m$^2$-sized housing unit was suggested.

• Journal of Korean Society for Quality Management
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• v.40 no.2
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• pp.145-155
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• 2012

The purpose of this study is to suggest the direction of improving service quality in the defense logistics support. For this, this study compares and analyzes the perceived service quality between customer(using unit) and defense logistics support unit by using SERVPERF model. Supply, military meals, and maintenance are carrying out the mission as core function of defense logistics support and also encounter with customer. In this empirical analysis, the service quality is composed of four factors, and there are significant difference in perception level of service quality between them. Also, the relationship between factors of service quality and revisit intention shows significant difference statistically, and the customer orientation and responsiveness are key affecting factors on revisit intention.

• Journal of East-West Nursing Research
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• v.23 no.1
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• pp.45-52
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• 2017

Purpose: This study was to identify the effects of self-resilience and social support on reality shock among new graduate nurses. Methods: The data was collected using self-reported questionnaires from a convenience sample of 111 new graduate nurses. The data was analyzed by descriptive statistical, independent t-test, ANOVA, Scheffe test, Pearson correlation coefficient, and multiple regression via the SPSS Window 23.0 program. Results: Among general and work related characteristics, factors that have shown significant differences on reality shock were gender (t=-2.29, p=.024), work unit (t=3.31, p=.023) and whether they are working at unit they desired (t=-5.08, p<.001). Reality shock has shown a negative correlation with self-resilience (r=-.51, p<.001) and social support (r=-.41, p<.001). Factors that affected the reality shock on new graduate nurses were self-resilience (${\beta}=-.43$, p<.001), whether they are working at unit they desired (${\beta}=.35$, p<.001) and their currently work unit (${\beta}=-.17$, p=.028). These factors take into account of 38.0% of overall reality shock. Conclusion: The results suggest that self-resilience, desired unit and current work unit should be considered as factors when developing an intervention to alleviate the reality shock experienced by new graduate nurses.

• Korean Medical Education Review
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• v.16 no.1
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• pp.16-24
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• 2014

The development of information technology (IT) has led to changes in medical education. IT has been used for e-learning and e-teaching, e-assessment, e-logistics, and e-administration. Pusan National University School of Medicine has developed its own educational information system using IT to support students' learning and assessment and to manage curricular activities. Based on our experience, we propose six suggestions for designing new software, specifically regarding simplifying the design for users, communication with the programmer, a rapid cycle from design to implementation, orientation support for users, backup and security support, and obtaining patents. Collaborating with the Department of Medical Informatics within the School of Medicine has advantages, and an alliance among medical schools can simplify the development of software. In any case, curricular innovation should precede the introduction of technology because all technologies should support curricular goals.

• Korean Institute of Interior Design Journal
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• v.16 no.3 s.62
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• pp.66-75
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• 2007

In this study, by comparing the development and the space types of local and foreign flexible apartments, basic data will be derived for the development of various flexible types of apartments in Korea. A total of 60 unit plans, including 30 domestic cases and 30 overseas cases of flexible apartments, are analyzed for this study. In terms of the unit plan types, Korean apartments usually had a wide front bay with shallow depth, placing more rooms on the front bay; whereas foreign apartments tend to have various unit plan types: (1) a narrow front bay with deep depth, (2) a wide front bay with shallow depth, and (3) variegated open-plan types. Many apartments in foreign countries had a double-layered structure with the. upstairs and downstairs areas. In terms of the flexible types, many Korean apartments achieved interior flexibility using non-bearing wall or sliding doors; whereas foreign apartments had a flexible space by separating the support elements and the infill elements. There was found to be a close relationship between the location of support elements and the variability of unit plans. Support elements can be placed largely into three locations: (1) Between the front side bay and the rear side bay, (2) in the center bay of a unit plan, and (3) others. Depending on the location of support elements, various types of flexible unit plans can be created. Through a comparative analysis of domestic and foreign apartments, basic data that can be used for developing various flexible unit plans was derived.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.4
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• pp.281-296
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• 2021

The beneficial effects of hypoxic preconditioning are abolished in the diabetes. The present study was designed to investigate the protective effects and mechanisms of repeated episodes of whole body hypoxic preconditioning (WBHP) in db/db mice. The protective effects of preconditioning were explored on diabetes-induced vascular dysfunction, cognitive impairment and ischemia-reperfusion (IR)-induced increase in myocardial injury. Sixteen-week old db/db (diabetic) and C57BL/6 (non-diabetic) mice were employed. There was a significant impairment in cognitive function (Morris Water Maze test), endothelial function (acetylcholine-induced relaxation in aortic rings) and a significant increase in IR-induced heart injury (Langendorff apparatus) in db/db mice. WBHP stimulus was given by exposing mice to four alternate cycles of low (8%) and normal air O₂ for 10 min each. A single episode of WBHP failed to produce protection; however, two and three episodes of WBHP significantly produced beneficial effects on the heart, brain and blood vessels. There was a significant increase in the levels of brain-derived neurotrophic factor (BDNF) and nitric oxide (NO) in response to 3 episodes of WBHP. Moreover, pretreatment with the BDNF receptor, TrkB antagonist (ANA-12) and NO synthase inhibitor (L-NAME) attenuated the protective effects imparted by three episodes of WBHP. These pharmacological agents abolished WBHP-induced restoration of p-GSK-3β/GSK-3β ratio and Nrf2 levels in IR-subjected hearts. It is concluded that repeated episodes of WHBP attenuate cognitive impairment, vascular dysfunction and enhancement in IR-induced myocardial injury in diabetic mice be due to increase in NO and BDNF levels that may eventually activate GSK-3β and Nrf2 signaling pathway to confer protection.

• Journal of Korean Critical Care Nursing
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• v.3 no.1
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• pp.79-88
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• 2010

Optimal nutrition serves to maintain normal organ function and to preserve body energy stores to guarantee survival during times of shortage of food. Adequate nutrition of intensive care unit (ICU) patients improves outcome, while malnutrition is strongly associated with increased morbidity and mortality rates among critically ill patients. Previously published researches showed that trials of nutritional support in critical illness rarely fulfill basic quality requirements. Nutrition support plays a vital role in the prevention and treatment of nutritional deficiencies in at-risk, critically ill patients. This paper reviewed the challenges in determining critically ill patients' nutrition requirements including nutrition assessment, determination of caloric requirements then providing them with adequate nutrition support while in the ICU with the guidelines published by Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition. Nutrition support can be effectively enhanced by using the guidelines.

• Journal of Engineering Education Research
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• v.18 no.6
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• pp.64-69
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• 2015

A video-work story analysis system based on emotional state measurement includes a content provision unit which provides story content of a video-work, a display unit which displays content provided by the content provision unit, an emotional state measurement unit which measures a tense-relaxed emotional state of a viewer viewing the displayed story content, a story pattern analysis unit which analyzes the tense-relaxed emotional state measured from the emotional state measurement unit according to a scene in the story content provided by the content provision unit, and a story pattern display unit which prints out an analysis result or displays the analysis result as an image. The emotional state measurement unit measures a tense or relaxed emotional state through one or more analyses among a brainwave analysis, a vital sign analysis, or an ocular state analysis. A writer may obtain support in an additional scenario modification work, and an investor may obtain support in making a decision through the above description. Furthermore, the video-work story analysis system and analysis method based on emotional state measurement may extract a particular pattern with respect to a change in an emotional state of a viewer, compile statistics, and analyze a correlation between a story and an emotional state.

• Korean Journal of Adult Nursing
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• v.26 no.6
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• pp.621-629
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• 2014

Purpose: The purpose of this study was to investigate the nutritional support, gastric residual volume, and nutritional status of the intensive care unit (ICU) patients on enteral feeding. Methods: A descriptive longitudinal design was used to collect 5 day data on enteral nutrition of 52 ICU patients in an university hospital. Nutritional support was calculated with actual caloric intake compared to individual caloric requirement. Residual volumes were measured prior to routine feedings, and the serum albumin levels and the total lymphocyte counts were checked to evaluate nutritional status. The data were analyzed using one group repeated measures ANOVA, paired t-test, and Spearman's bivariate correlation analysis. Results: The subjects received their first enteral feeding on the $5.75^{th}$ day of ICU admission. The mean nutritional support rate was 49.1% of the requirement, however prescription rate and support rate were increased as time goes by. Gastric residual volumes were less than 10 cc in 95% cases. A significant negative correlation was found between nutritional support and nutritional status. Conclusion: The nutritional support for ICU patient was low compared to the requirement, and their nutritional status was worse than at the time of ICU admission. Further studies are necessary to develop nursing interventions for improving nutritional support for ICU patients.