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Lymphocyte Subpopulations and Proliferation of T cells, Phagocytic Activity of Leukocytes on Alcoholics (알코올중독자의 백혈구탐식능, 림프구아형 및 증식능)

  • 김용호;서병배;이정녀;김영훈
    • Biomedical Science Letters
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    • v.2 no.2
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    • pp.167-174
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    • 1996
  • Alcoholics increased susceptibility to microbial infection that is associated with decreased immunity. but there has been little experimental evidence to support alcoholics-induced increase of microbial infection directly in non-specific immunity. Therefore, we were used the method of phagocytic-plaque including all the stimulating factors for the phagocytosis, subtypes of lymphocytes and T-lymphocyte proliferation. The experimental groups were divided into 3 groups: (1) alcoholics who were hospitalized less than 1 week (newly hospitalized alcoholics), (2) alcoholics who were hospitalized more than 2 weeks (old hospitalized alcoholics), (3) healthy blood donors. We have studied 98 alcoholics and 35 healthy blood donors and control groups. A physician has checked the biological markers and diagnosed the body-condition alcoholics. The immunity and non-specific immunity on the alcoholics were analyzed by using the simultest kit and flow cytometry. Proliferation of the lymphocytes was analyzed by the phytohemmagglutinine mitogen. Phagocytosis and migration properties of leukocytes were identified on the layer formed by Staphylococcus aureus Cowan I strain. Biological markers of alcoholics and control groups, by such as blood glucose, ${\gamma}$-glutamyl transpeptidase and mean corpuscular volumes of red blood cells, were determined by biochemical and hematological methods. Compared with control groups, cluster of differentiation (CD)3+, CD8+ and CD19+ in alcoholic were more decreased except CD4+/CD8+ ratio. Proliferation of the T-lymphocytes, phagocytosis and migration properties of the leukocytes in alcoholics were decreased compared with those of control groups. According to the results observed in our experiment, they can be summerized as follows: 1, Cellular, humoral and non-specific immunities, are markedly decreased in alcoholics than those in control groups. 2. It is inferred that Phagocytic plaque formation is a very useful method to evaluate phagocytosis and migration properties of the alcoholic leukocytes 3. It is thought that the subtypes of lymphocytes, especially CD4+/CD8+ ratio, are essential methods to analyzed the alcoholic immunity. 4. Specific and non-specific immunity on the old hospitalized alcoholics was slightly increased, which depends upon the alcoholic medication.

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Role of Wetland Plants as Oxygen and Water Pump into Benthic Sediments (퇴적물내의 산소와 물 수송에 관한 습지 식물의 역할)

  • Choi, Jung-Hyun;Park, Seok-Soon
    • Korean Journal of Ecology and Environment
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    • v.37 no.4 s.109
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    • pp.436-447
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    • 2004
  • Wetland plants have evolved specialized adaptations to survive in the low-oxygen conditions associated with prolonged flooding. The development of internal gas space by means of aerenchyma is crucial for wetland plants to transport $O_2$ from the atmosphere into the roots and rhizome. The formation of tissue with high porosity depends on the species and environmental condition, which can control the depth of root penetration and the duration of root tolerance in the flooded sediments. The oxygen in the internal gas space of plants can be delivered from the atmosphere to the root and rhizome by both passive molecular diffusion and convective throughflow. The release of $O_2$ from the roots supplies oxygen demand for root respiration, microbial respiration, and chemical oxidation processes and stimulates aerobic decomposition of organic matter. Another essential mechanism of wetland plants is downward water movement across the root zone induced by water uptake. Natural and constructed wetlands sediments have low hydraulic conductivity due to the relatively fine particle sizes in the litter layer and, therefore, negligible water movement. Under such condition, the water uptake by wetland plants creates a water potential difference in the rhizosphere which acts as a driving force to draw water and dissolved solutes into the sediments. A large number of anatomical, morphological and physiological studies have been conducted to investigate the specialized adaptations of wetland plants that enable them to tolerate water saturated environment and to support their biochemical activities. Despite this, there is little knowledge regarding how the combined effects of wetland plants influence the biogeochemistry of wetland sediments. A further investigation of how the Presence of plants and their growth cycle affects the biogeochemistry of sediments will be of particular importance to understand the role of wetland in the ecological environment.

Effects of Several Amendment Materials on Salt Accumulation and Kentucky Bluegrass (Poa pratensis L.) Growth in Sand Growing Media Established Over the Reclaimed Saline Soil (염해지 토양을 기반으로 조성된 모래 지반구조에서 토양개량제 종류에 따른 토양내 염류 집적과 켄터키 블루그래스(Poa pratensis L.)의 생육)

  • Rahayu, Rahayu;Yang, Geun-Mo;Choi, Joon-Soo
    • Asian Journal of Turfgrass Science
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    • v.25 no.2
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    • pp.208-216
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    • 2011
  • The purpose of this study was to find soil-amendment materials those support the growth of Kentucky bluegrass and reduce salt accumulation at the sand based growing media in saline conditions. Rootzone profile in columns consisted of 20 cm of top soil, 20 cm coarse sand as capillary rise interruption layer and 10 cm reclaimed paddy soil as the base of the profile. Top soils were mixtures of dredged sand (DS) and amendment with compositions of 90% sand + 10% peat moss (SP), 80% sand + 10% soil + 10% bottom ash (SSoBa), 80% sand + 20% soil (SSo), 90% sand + 5% peat + 5% zeolite (SPZ), and 80% sand + 20% bottom ash (SBa). The top soil mixtures of DS and amendments were treated with and without gypsum (Gp). The columns were soaked into 5 cm depth saline water reservoir with the salinity level of $3-5dSm^{-1}$. Irrigation of $2dSm^{-1}$ saline water with rate of $5.7mm\;day^{-1}$ was applied by 3 day interval. Application of zeolite decreased SAR, application of gypsum decreased ECe of the sand amended by peat + zeolite and decreased the SAR of sand amended by bottom ash. The SP and SSoGp resulted in higher clipping dry weight of Kentucky bluegrass. The SSoGp and SPZGp showed longer root lengths. The SP and SBaGp showed higher visual quality. Addition of gypsum to soil and bottom ash treatments resulted in the increased shoot growth, whereas additional gypsum to the treatments of peat, soil and zeolite increased the root growth of Kentucky bluegrass.

Management of the Nakdong-Jeongmaek based on the Characteristics of Cold Air - Focused on Busan, Ulsan, Pohang - (찬공기 특성을 고려한 낙동정맥 관리방안 연구 - 부산, 울산, 포항 인근을 대상으로 -)

  • Eum, Jeong-Hee;Son, Jeong-Min
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.5
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    • pp.103-115
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    • 2016
  • This study aims to analyze the properties of cold air production and its flow of Nakdong-Jeongmaek(mountain ranges), and to suggest management strategies for Nakdong-Jeongmaek in order to enhance the green air conditioning functions of Jeongmaek. For this purpose, three study sites including Gudeoksan Mountain and the vicinity in Busan, Goheonsan Mountain and the vicinity in Ulsan, and Unjusan Mountain and the vicinity in Pohang were selected. The results found that cold air flow and its height of the three study sites were analyzed based on topographic properties and land use. Management strategies for preserving and enhancing their temperature reduction functions were suggested. The cold air produced in the vicinity of Gudeoksan was not fully developed and spread because of the high-density development at the border of Jeongmaek. Since high pressures of development are expected at the border, high conservation policies are required. In the vicinity of Goheonsan, where the agricultural complex and industrial park are located, cold air flows well throughout the entire study site thanks to fully developed cold air in the wide, flat valley. Hence, plans to maintain the current cold air flow are required, and conservation plans to mitigate future developments are also needed in the flat valley. The cold air in Unjusan and the vicinity with its complex and narrow mountain valleys gradually develops into valley bottoms. In order to take advantage of the terrain, the valley near the cold air production areas are preserved. In particular, special plans are required to prevent damage to the cold air layer near Youngcheonho Lake, where the highest height of cold air was recorded due to the closed and lower terrain feature. This study could support the establishment of systematic management plans of Nakdong-Jeongmaek to preserve and enhance its green air conditioning functions.

Fabrication and Performance of Anode-Supported Flat Tubular Solid Oxide Fuel Cell Unit Bundle (연료극 지지체식 평관형 고체산화물 연료전지 단위 번들의 제조 및 성능)

  • Lim, Tak-Hyoung;Kim, Gwan-Yeong;Park, Jae-Layng;Lee, Seung-Bok;Shin, Dong-Ryul;Song, Rak-Hyun
    • Journal of the Korean Electrochemical Society
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    • v.10 no.4
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    • pp.283-287
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    • 2007
  • KIER has been developing the anode-supported flat tubular solid oxide fuel cell unit bundle for the intermediate temperature($700{\sim}800^{\circ}C$) operation. Anode-supported flat tubular cells have Ni/YSZ cermet anode support, 8 moi.% $Y_2O_3$ stabilized $ZrO_2(YSZ)$ thin electrolyte, and cathode multi-layer composed of Sr-doped $LaSrMnO_3(LSM)$, LSM-YSZ composite, and $LaSrCoFeO_3(LSCF)$. The prepared anode-supported flat tubular cell was joined with ferritic stainless steel cap by induction brazing process. Current collection for the cathode was achieved by winding Ag wire and $La_{0.6}Sr_{0.4}CoO_3(LSCo)$ paste, while current collection for the anode was achieved by using Ni wire and felt. For making stack, the prepared anode-supported flat tubular cells with effective electrode area of $90\;cm^2$ connected in series with 12 unit bundles, in which unit bundle consists of two cells connected in parallel. The performance of unit bundle in 3% humidified $H_2$ and air at $800^{\circ}C$ shows maximum power density of $0.39\;W/cm^2$ (@ 0.7V). Through these experiments, we obtained basic technology of the anode-supported flat tubular cell and established the proprietary concept of the anode-supported flat tubular cell unit bundle.

Comparison of Population Monitoring Methods for Breeding Forest Birds in Korean Temperate Mixed Forests (국내 온대 혼효림에 서식하는 산림성 조류의 번식기 개체군 모니터링 방법에 대한 비교)

  • Nam, Hyun-Young;Choi, Chang-Yong;Park, Jin-Young;Hur, Wee-Haeng
    • Journal of Korean Society of Forest Science
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    • v.108 no.4
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    • pp.663-674
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    • 2019
  • Birds are effective ecological indicators but there is no national protocol in place to monitor population dynamics of forest birds in Korea. To support the establishment of future monitoring protocols, we compared the results of two generally used monitoring methods for forest bird surveys in two temperate mixed forests in central Korea. There was no statistical difference in the number of species and individuals detected per unit survey effort when comparing line transects and point counts. The number of species and individuals were higher in a five-minute count than in a three-minute point count, but the total accumulated number of expected observed species showed no difference between the two count durations. The number of observed species and individuals increased in both methods as plot radius or transect width increased, suggesting that multi-layer or multi-band surveys may be useful for quantitative and qualitative objectives. The decreasing number of observed species and individuals after sunrise suggested that bird monitoring should be conducted earlier in the morning, within four hours after sunrise. To detect 70% of the total number of species, 7.0 to 7.6 survey hours, equivalent to 42 three-minute counts (95% confidence interval [CI]: 26 to 61) or 33 five-minute counts (95% CI: 19 to 53) were needed for unlimited radius point counts. On the other hand, 4.8 survey hours, equivalent to 26 line transect counts (95% CI: 15 to 45) using 200-m transects with unlimited width, were required to achieve the same level of species detection. Therefore, the line transect method may be more effective than the point count method, at least in terms of local species richness assessment. For national forest bird monitoring, our data indicated that one or both survey methods can be selected as a basic protocol, based on the goals and scales of monitoring, forest types, and the conditions of the target areas.

User-Perspective Issue Clustering Using Multi-Layered Two-Mode Network Analysis (다계층 이원 네트워크를 활용한 사용자 관점의 이슈 클러스터링)

  • Kim, Jieun;Kim, Namgyu;Cho, Yoonho
    • Journal of Intelligence and Information Systems
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    • v.20 no.2
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    • pp.93-107
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    • 2014
  • In this paper, we report what we have observed with regard to user-perspective issue clustering based on multi-layered two-mode network analysis. This work is significant in the context of data collection by companies about customer needs. Most companies have failed to uncover such needs for products or services properly in terms of demographic data such as age, income levels, and purchase history. Because of excessive reliance on limited internal data, most recommendation systems do not provide decision makers with appropriate business information for current business circumstances. However, part of the problem is the increasing regulation of personal data gathering and privacy. This makes demographic or transaction data collection more difficult, and is a significant hurdle for traditional recommendation approaches because these systems demand a great deal of personal data or transaction logs. Our motivation for presenting this paper to academia is our strong belief, and evidence, that most customers' requirements for products can be effectively and efficiently analyzed from unstructured textual data such as Internet news text. In order to derive users' requirements from textual data obtained online, the proposed approach in this paper attempts to construct double two-mode networks, such as a user-news network and news-issue network, and to integrate these into one quasi-network as the input for issue clustering. One of the contributions of this research is the development of a methodology utilizing enormous amounts of unstructured textual data for user-oriented issue clustering by leveraging existing text mining and social network analysis. In order to build multi-layered two-mode networks of news logs, we need some tools such as text mining and topic analysis. We used not only SAS Enterprise Miner 12.1, which provides a text miner module and cluster module for textual data analysis, but also NetMiner 4 for network visualization and analysis. Our approach for user-perspective issue clustering is composed of six main phases: crawling, topic analysis, access pattern analysis, network merging, network conversion, and clustering. In the first phase, we collect visit logs for news sites by crawler. After gathering unstructured news article data, the topic analysis phase extracts issues from each news article in order to build an article-news network. For simplicity, 100 topics are extracted from 13,652 articles. In the third phase, a user-article network is constructed with access patterns derived from web transaction logs. The double two-mode networks are then merged into a quasi-network of user-issue. Finally, in the user-oriented issue-clustering phase, we classify issues through structural equivalence, and compare these with the clustering results from statistical tools and network analysis. An experiment with a large dataset was performed to build a multi-layer two-mode network. After that, we compared the results of issue clustering from SAS with that of network analysis. The experimental dataset was from a web site ranking site, and the biggest portal site in Korea. The sample dataset contains 150 million transaction logs and 13,652 news articles of 5,000 panels over one year. User-article and article-issue networks are constructed and merged into a user-issue quasi-network using Netminer. Our issue-clustering results applied the Partitioning Around Medoids (PAM) algorithm and Multidimensional Scaling (MDS), and are consistent with the results from SAS clustering. In spite of extensive efforts to provide user information with recommendation systems, most projects are successful only when companies have sufficient data about users and transactions. Our proposed methodology, user-perspective issue clustering, can provide practical support to decision-making in companies because it enhances user-related data from unstructured textual data. To overcome the problem of insufficient data from traditional approaches, our methodology infers customers' real interests by utilizing web transaction logs. In addition, we suggest topic analysis and issue clustering as a practical means of issue identification.

Synthesis Gas Production via Partial Oxidation, CO2 Reforming, and Oxidative CO2 Reforming of CH4 over a Ni/Mg-Al Hydrotalcite-type Catalyst

  • Song, Hoon Sub;Kwon, Soon Jin;Epling, William S.;Croiset, Eric;Nam, Sung Chan;Yi, Kwang Bok
    • Clean Technology
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    • v.20 no.2
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    • pp.189-201
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    • 2014
  • Partial oxidation, $CO_2$ reforming and the oxidative $CO_2$ reforming of $CH_4$ to produce synthesis gas over supported Ni hydrotalcite-type ($Ni_{0.5}Ca_{2.5}Al$ catalyst) catalysts were carried out and the effects of metal supports (i.e.; Mg and Ca) on the formation of a stable double-layer structure on the catalysts were evaluated. The $CH_4$ reforming stability was determined to be affected by the differences in the interaction strength between the active Ni ions and support metal ions. Only a Ni-Mg-Al composition produced a highly stable hydrotalcite-type double-layered structure; while the Ni-Ca-Al-type composition did not. Such structure provides excellent stability for the catalyst (-80% efficiency) as confirmed by the long-term $CO_2$ reforming test (-100 h), while the Ni-Ca-Al catalyst exhibited deactivation phases starting at the beginning of the reaction. The interaction strength between the active metal (Ni) and the supporting components (Mg and Al) was determined by temperature-programed reduction (TPR) analyses. The affinity was also confirmed by the TPR temperature because the Ni-Mg-Al catalyst required a higher temperature to reduce the Ni relative to the Ni-Ca-Al catalyst. The highest initial activity for synthesis gas production was observed for the $Ni_{0.5}Ca_{2.5}Al$ catalyst; however, this activity decreased quickly due to coke formation. The $Ni_{0.5}Ca_{2.5}Al$ catalyst exhibited a high reactivity and was more stable than the other catalysts because it had a higher resistance to coke formation.

An Analysis of Middle school Technology Teachers' Stage of Concerns about Maker Education By Concerns-Based Adoption Model (관심기반수용모형(CBAM)에 의한 중학교 기술교사의 메이커 교육 관심도 분석)

  • Kang, Sang-Hyun;Kim, Jinsoo
    • 대한공업교육학회지
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    • v.44 no.2
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    • pp.104-122
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    • 2019
  • In the era of the fourth industrial revolution, maker education is drawing attention as a method of student-led education. At a time when interest in maker education is also growing in technology education, figuring out what stage of concern(SoC) a middle school technology teacher is critical to effective implementation. This study analyzed SoC in maker education by layer sampling among 400 middle school technology teachers using Concerns-based adoption model. SoC was then obtained by measuring the origin using the SoCQ and then presenting it as a SOCQ profile. Gender, training experience with two lower variables were analyzed using t verification, working cities, teaching experience with more than three lower variables were analyzed using one-way ANOVA. Studies showed that SoC in maker education of middle school technology teachers showed the most similar characteristics to that of non-users. The difference in concern depending on gender was that male teachers were more concerned in maker education than female teachers. The difference in concern depending on the working city was that teachers working in the township were more concerned in the maker education than teachers working in the large city, and the difference in concern depending on the teaching career was higher among teachers with middle experience than those with low and high experience. There was also a higher stage of concern in maker education than in teachers without training experience. Therefore, it is necessary to provide middle school technology teachers with an introduction to the maker education and various information, teaching, learning and evaluation data to enhance overall concern and to support the use and evaluation of the maker education in the classroom by providing various teacher training and consulting on the maker education in the future. Further, through further study, we should conduct study that analyzes both Stage of Concern, Level of Use and Innovation Configuration, to put in the effort for effective settlement of maker education.

Development of Greenhouse Cooling and Heating Load Calculation Program Based on Mobile (모바일 기반 온실 냉난방 부하 산정 프로그램 개발)

  • Moon, Jong Pil;Bang, Ji Woong;Hwang, Jeongsu;Jang, Jae Kyung;Yun, Sung Wook
    • Journal of Bio-Environment Control
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    • v.30 no.4
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    • pp.419-428
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    • 2021
  • In order to develope a mobile-based greenhouse energy calculation program, firstly, the overall thermal transmittance of 10 types of major covers and 16 types of insulation materials were measured. In addition, to estimate the overall thermal transmittance when the cover and insulation materials were installed in double or triple layers, 24 combinations of double installations and 59 combinations of triple installations were measured using the hotbox. Also, the overall thermal transmittance value for a single material and the thermal resistance value were used to calculate the overall thermal transmittance value at the time of multi-layer installation of covering and insulating materials, and the linear regression equation was derived to correct the error with the measured values. As a result of developing the model for estimating thermal transmittance when installing multiple layers of coverings and insulating materials based on the value of overall thermal transmittance of a single-material, the model evaluation index was 0.90 (good when it is 0.5 or more), indicating that the estimated value was very close to the actual value. In addition, as a result of the on-site test, it was evaluated that the estimated heat saving rate was smaller than the actual value with a relative error of 2%. Based on these results, a mobile-based greenhouse energy calculation program was developed that was implemented as an HTML5 standard web-based mobile web application and was designed to work with various mobile device and PC browsers with N-Screen support. It had functions to provides the overall thermal transmittance(heating load coefficient) for each combination of greenhouse coverings and thermal insulation materials and to evaluate the energy consumption during a specific period of the target greenhouse. It was estimated that an energy-saving greenhouse design would be possible with the optimal selection of coverings and insulation materials according to the region and shape of the greenhouse.