• Journal of Nutrition and Health
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• 제5권2호
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• pp.91-103
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• 1972

Zinc is one of the essential trace elements in the living organism for growth and health. The first identified metalloenzyme, carbonic anhydrase, is a zinc compound and several others have been described since. Among zinc deficiency syndromes in animals porcine parakeratosis has been successfully treated with zinc supplements, and in man a syndrome of anemia, hypogonadism, hepatosplenomegaly, and dwarfism, prevalent in parts of Iran and Egypt, has been ascribed to lack of zinc in the diet. Dietary zinc excess in the rat is manifested by a hypochromic, microcytic anemia, poor growth, reduction in liver catalase and cytochrome oxidase. The present study is an attempt to delineate the changes of tissue contents of trace elements, especially of iron, copper and zinc in liver and kidneys of the rats. Weanling albino rats, weighing 60 to 80gm. were used in this experiments. The rats were housed in cages with aluminum floors and received feed and distilled water ad libitum. Animals were divided into three groups, control, low zinc diet and high zinc diet groups. The high zinc diet group was subdivided into 0.5% Zn and 0.7%Zn groups. The supplementary copper or iron was added to the high dietary zinc groups. The animals were sacrificed and the tissues were washed several times with deionized water. The wet digested samples were analyzed by Hitachi Model 207 atomic absorption spectro-photometer for the determination of iron, copper and zinc in the liver and kidney. Hemoglobin level in the blood was measured by cyanmethemoglobin method. The results of this study are as follows: 1) All rats fed high zinc diets and low zinc diets gained less weight than control. Weight gain was not improved by the supplementary copper or iron and both. 2) Hemoglobin concentration was decreased significantly in the rats fed high zinc diets and less in the low zinc diet. Supplementary copper and iron to the higher zinc diet appeared to give some improvement of anemia. 3) The iron contents of the liver and kidneys were significantly decreased in the high zinc groups and the reduction was more significantly in the rats receiving higher zinc diet (0.7%). The supplementary copper caused a further depression of liver iron. On the other hand, the iron, added to the high zinc diet lessoned the severity of the decrease in liver iron and caused kidney iron to be maintained almost at the level found in the rats fed by zinc and supplementary copper diet. 4) High zinc diets did not change copper content of the liver and kidney. Supplementary copper elevated the concentration in the liver and kidney and added iron had no effect on the accumulation of copper in the liver and kidneys. 5) The high zinc diets caused marked increases of zinc content in the liver and kidney. Supplementary iron to the high zinc diet caused increases of zinc contents of liver and kidneys.

• 분석과학
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• 제36권3호
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• pp.105-112
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• 2023

라이코펜은 카로티노이드의 일종으로 심혈관계 위험인자, 혈중지질, 혈압 등을 낮추는 효과를 가지는 것으로 알려져 있어, 액상 내용물이 충진된 연질캡슐, 고상 내용물이 충진된 경질캡슐을 포함하는 다양한 제형의 라이코펜 건강기능식품이 유통되고 있다. 그러나, 최근 본 연구진은 현 건강기능식품공전 중 라이코펜 시험법의 고상 건강기능식품 적용에 한계가 있음을 확인하였다. 따라서, 본 논문에 비누화 반응 및 액체크로마토그래프에 기반한 신규 고상 건강기능식품 중 라이코펜 시험법의 개발을 보고하는 바이다. 신규 개발 시험법은 식품의약품안전평가원 가이드라인에 의거하여 밸리데이션 되었고, 모든 항목 결과가 가이드라인 기준을 만족함(특이성, 직선성 r²≥0.991, 정량한계 0.0149 mg/mL, 정확도(회수율) 92.70~97.18 %, 반복성(회수율의 상대표준편차) 0.85~1.59 %, 재현성(실험실 간 회수율의 상대표준편차) 3.70 %)을 확인하였다. 또한 인증표준물질을 활용한 적용성 평가에서도 높은 정확도(98.81~101.59 %)가 관찰되어, 신규 시험법의 개발이 성공적이었음을 재확인하였다. 따라서, 신규 개발 시험법은 향후 고상 라이코펜 건강기능식품 관리에 활용되어 국내 건강식품안전관리에 기여할 수 있을 것으로 판단된다.

• 설비공학논문집
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• 제8권4호
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• pp.527-536
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• 1996

Convective nucleate boiling and burnout heat flux have been studied on a flat, downward facing, constant heat flux surface cooled by an impinging water jet. The tests are progressed from low, nonboiling power to high, burnout heat flux power. The jet velocity and the subcooling do not affect the nucleate boiling curve of $q{\sim}{\Delta}T_{sat}$ diagram, but the supplementary water height affects the curve. For the case of dimensionless height of supplementary water S/D=1, the boiling curve shift to the heigher heat flux than that of S/D=0 or S/D=2. Burnout heat flux is enhanced with increasing jet velocity and subcooling. Also. by using the supplementary water(S/D=1 or S/D=2), burnout heat flux is larger than that of the simple water jet(S/D=0). A generalized correlation for the burnout heat flux data in the present boiling system with an impinging water jet is successfully evolved.

• 대한기계학회논문집
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• 제15권6호
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• pp.1933-1947
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• 1991

본 연구에서는 특징형상기반 CAD 시스템의 기계가공을 고려한 기하학적 모델 링 기능과 부형상의 합성과 해석을 위한 사출성형에 관한 광범위한 지식을 연계, 종합 한 형태의 지식형 CAD 시스템을 제안하였다.

• 대한한방부인과학회지
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• 제23권4호
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• pp.67-79
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• 2010

Purpose: To evaluate the effect of Korean medical treatment as supplementary treatment method in ART. Methods: The research was investigated with Korean, Chinese and western medical clinical journals of ART with herbal medicine, acupuncture, and other oriental medical treatment as supplementary treatment. Results: ART with additional herbal treatment achieved notably better result when ovulation rate, quality of oocyte, pregnant rate were compared. In the indepth review and analysis of five journals of ART with acupuncture intervention, firm effective results were not found, however, acupuncture intervention on patients with embryo transplantation had higher achievement rate in artificial insemination. Conclusions: According to the review of the Korean, Chinese, and western medical journals of the effect of Korean medical treatment as supplementary treatment method in ART, acupuncture, herbal medicine, and other oriental medical therapies in ART contribute to the improvement of the outcome of ART. The limit in the research was limited strong enough well-designed RCT studies as evidence for they were very seldom.

• 응용통계연구
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• 제8권1호
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• pp.51-60
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• 1995

크기가 $n \times p$인 자료행렬에서 p개의 변수들과 성격이 다소 다른 $p_s$개의 변수를 같이 고려한 크기가 $n \times (p + p_s)$ 자료행렬이 있다 하자. 전통적 주성성분분석은 성격이 다른 변수들로 인하여 효과적인 결과를 제공하지 못한다. 본 논문에서는 이런 점을 개선하기 위해서 성격이 다른 $p_s$개의 변수를 추가변수로 두는 추가적 주성분분석을 소개하려 한다. 이 기법은 전통적 주성분분석의 대수적,기하적인 면을 따른다. 그리고 전통적 주성분분석과 추가적 주성성분분석을 활용한 한국 프로야구의 8개팀과 1982-1992년 동안의 14개의 부문별 기록에 대한 전형적인 자료분석의 한 예를 제시한다. 더불어 두 분석의 결과도 비교하였다.

• 대한지역사회영양학회지
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• 제2권3호
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• pp.366-375
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• 1997

This study was conducted to evaluate the effectiveness and preferences of supplementary drinks for very old subjects who are likely to be malnourished. Twenty- five elderly subjects were divided into two groups. The supplemented group(N=15) received 500mls of nutrient supplement(New Care) two times daily for 4 weeks. This resulted in a significant increase in the total calories, protein, minerals and vitamins. Nutritional status was assessed both anthropometrically and biochemically, before and after the study period. A significant improvement in mid arm circumference, triceps skinfold thickness and serum albumin were observed in the supplemented group but not in the control group. There is a possibility that most of the elderly were in an anemic state at the beginning of the study since their mean hematologic parameters were within the lower normal range while their mean serum osmolarities was slightly higher than normal, . Although mean serum hemoglobin and hematocrit were not increased significantly, th percentage of the recovery rate from anemia in the supplemented group was higher than in the control group. Total lymphocyte count also showed similar tendency. Sensory evaluation of nutritional supplementary drinks were relatively good and the elderly showed great interest in nutrient supplements. This study suggests that a nutritional status of poorly nourished elderly subjects can be improved by providing them with nutritional supplementations.

• 대한전자공학회논문지SP
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• 제48권3호
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• pp.119-124
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• 2011

보간 필터는 통신과 멀티미디어 응용프로그램에 널리 사용된다. 다항식 보간은 보간된 값을 얻기 위해서 입력정보에 따른 다항식의 계수를 계산한다. 최근에 다항식 보간방법의 성능을 향상시키기 위하여 보조필터를 이용한 FIR 보간방법이 제안되었다. 본 논문에서는 최대값 또는, 최소값 계산 등 특정 순간의 보간 값만 필요한 응용에서 보간필터의 성능을 더욱 향상시킬 수 있는 보조필터를 이용한 가중치 적용 보간방법을 제안한다. 제안한 방법을 X-선 형광분석장치에서 사용되는 정규분포곡선에 대한 보간에 적용하여 기존 보간방법에 비해 더욱 우수한 보간 성능이 제공됨을 보인다.

• Asian-Australasian Journal of Animal Sciences
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• 제7권2호
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• pp.289-294
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• 1994

This report deals with the effect of levels of concentrate supplementary feeding (Nil, 0.25% BW and 0.75% BW) on the productivity of different genotypes (Thai native (TN), 25% Anglo-Nubian (AN), 50% AN and 75% AN) of female goats grazing newly established pasture in a tropical area. The major species of grass was Brachiaria mutica (33%) and of legumes was Centrosema pubescens (34%). There was no significant (p>0.05) difference between nil and 0.25% BW supplementary feeding for growth rate ($g/kg^{0.75}/d$). However, goats fed 0.75% BW supplementary feeding had significantly (p<0.01) higher growth rates than did other treatments. There was no significant (p>0.05) difference among genotypes and between age for growth rate. There was no interaction between feeding and genotype for growth rate.

• 대한기계학회논문집B
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• 제20권4호
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• pp.1395-1405
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• 1996

The purpose of this experimental research is to investigate the local heat transfer characteristics in the upward free water jet impinged on a downward flat plate of uniform heat flux. The inner shape of rectangular nozzle used was sine curve type and its contraction ratio of inlet to outlet area was five. Experimental parameters considered were Reynolds number, nozzle exit-flat plate distance, and level of supplementary water. Local Nusselt number was influenced by Reynolds number, Prandtl number, supplementary water level, and distance between the nozzle exit and flat plate. Within the impingement region, the Nusselt number has a maximum value on the nozzle center axis and decreases monotonically outward from center. Outside of the impingement region, on the other hand, the Nusselt number has a secondary peak near the position where the distance from nozzle center reaches four times the nozzle width. However if nozzle exit velocity exceeds 6.2 m/s, the secondary peak appears also in the impingement region. The empirical equation for the stagnation heat transfer is a function of Prandtl, Reynolds, and axial distance from the nozzle exit. The optimum level of supplementary water to augment the heat transfer rate at stagnation point was found to be twice the nozzle width.