• 대한전자공학회논문지
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• 제24권3호
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• pp.486-492
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• 1987

This study is an attempt to review the theories about the RF and microwave hyperthermia and to get the practical implementation of hyperthermia system on the basic clinical experiments with agar phantoms and four patients. The frequencies of RF power are 8 MHz and 16 MHz, which are effective for the heating of deep-seated and superficial tumors, and microwave is 2.45 GHz, also suitable for the heating of superficial tumors. Even if the long-term effect of clinical applications were not investigated for human living body, it was observee that the RF and microwave hyperthermias are effective for many kinds of cancers in the fixed frequency ranges.

• Journal of electromagnetic engineering and science
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• 제15권1호
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• pp.20-25
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• 2015

A circularly rotated array for a dual polarized applicator in a superficial hyperthermia system is proposed. The applicator has a wider effective treatment area due to the $180^{\circ}$ phase shift. The dual polarized circularly rotated array (DPCRA) suppresses overheating at the center of the array and helps evenly distribute the heat. This array provides a more effective treatment area than a lattice array when a $2{\times}2$ dual polarized array is fitted to the treatment area. The treatment area is 71.5% of the aperture, whereas the effective treatment areas of the $2{\times}2$ dual polarized lattice array (DPLA) and the single polarized array (SPA) are 57.2% and 38.6% of the same aperture, respectively. The measurement matches the simulation results without blood circulation effects. In a $2{\times}2$ array applicator, the proposed DPCRA has more heat uniformity than the DLA and the SPA.

• Radiation Oncology Journal
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• 제32권4호
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• pp.256-261
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• 2014

Purpose: We performed invasive thermometry to verify the elevation of local temperature in the liver during hyperthermia. Materials and Methods: Three 40-kg pigs were used for the experiments. Under general anesthesia with ultrasonography guidance, two glass fiber-optic sensors were placed in the liver, and one was placed in the peritoneal cavity in front of the liver. Another sensor was placed on the skin surface to assess superficial cooling. Six sessions of hyperthermia were delivered using the Celsius TCS electro-hyperthermia system. The energy delivered was increased from 240 kJ to 507 kJ during the 60-minute sessions. The inter-session cooling periods were at least 30 minutes. The temperature was recorded every 5 minutes by the four sensors during hyperthermia, and the increased temperatures recorded during the consecutive sessions were analyzed. Results: As the animals were anesthetized, the baseline temperature at the start of each session decreased by $1.3^{\circ}C$ to $2.8^{\circ}C$ (median, $2.1^{\circ}C$). The mean increases in temperature measured by the intrahepatic sensors were $2.42^{\circ}C$ (95% confidence interval [CI], 1.70-3.13) and $2.67^{\circ}C$ (95% CI, 2.05-3.28) during the fifth and sixth sessions, respectively. The corresponding values for the intraperitoneal sensor were $2.10^{\circ}C$ (95% CI, 0.71-3.49) and $2.87^{\circ}C$ (1.13-4.43), respectively. Conversely, the skin temperature was not increased but rather decreased according to application of the cooling system. Conclusion: We observed mean $2.67^{\circ}C$ and $2.87^{\circ}C$ increases in temperature at the liver and peritoneal cavity, respectively, during hyperthermia. In vivo real-time thermometry is useful for directly measuring internal temperature during hyperthermia.

• 대한의용생체공학회:의공학회지
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• 제10권2호
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• pp.179-184
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• 1989

There are microwave hyperthermia, microwave surgical knife, and microwave tissue coagulator etc. as the cure-appliance using microwave. The object of this paper is to develope the multipurpose cure-appliance which has the functions that can be used intestinal tumor as well as the existing superficial tumor. And this also have the function of surgical knife and tissue coagulator with endoscope. And then ascertain its functions through the experiments, and to suggest the direction for reserch hereafter.