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Bioassay in BALB/c mice exposed to low dose rate radiation (저선량율 방사선 조사한 BALB/c 마우스에서의 영향평가)

  • Kim, Sung-Dae;Gong, Eun-Ji;Bae, Min-Ji;Yang, Kwang-Mo;Kim, Joong-Sun
    • Journal of Radiation Protection and Research
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    • v.37 no.3
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    • pp.159-166
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    • 2012
  • The present study was performed to investigate the toxicity of low-dose-rate irradiation in BALB/c mice. Twenty mice of each sex were randomly assigned to four groups of five mice each and were exposed to 0 (sham), 0.02, 0.2, or 2 Gy, equivalents to low-dose-rate irradiation to 3.49 $mGy{\cdot}h^{-1}$. Urine, blood, and blood biochemistry were analyzed, and organ weight was measured. The low-dose-rate irradiation did not induce any toxicologically significant changes in mortality, clinical signs, body weight, food and water consumption, urinalysis, and serum biochemistry. However, the weights of reproductive organs including the testis, ovary, and uterus decreased in a dose-dependent manner. Irradiation at 2 Gy significantly decreased the testis, ovary, and uterus weights, but did not change the weights of other organs. There were no adverse effects on hematology in any irradiated group and only the number of neutrophils increased dose dependently. The low-dose-rate irradiation exposure did not cause adverse effects in mice at dose levels of 2 Gy or less, but the reproductive systems of male and female mice showed toxic effects.

Changes of Causative Allergen in Patients with Allergic Diseases in Chonbuk Province (전북지역 알레르기 환자에서 원인 알레르겐의 변화)

  • Jeon, Hyun-Sun;Lee, Yong-Chul;Lee, Heung-Bum;Rhee, Yang-Keun
    • Tuberculosis and Respiratory Diseases
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    • v.47 no.6
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    • pp.817-823
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    • 1999
  • Background: The prevalence of allergic disease has increased substantially over the past decades. The reasons for these trends are complex but include increased environmental allergen exposure. Environmental control measures are of particular importance in the prevention and management of allergic disease. Thus, we purposed to evaluate the changes of causative allergens in allergic patients in Chonbuk provincial area that began industralized recently. Method: To evaluate the allergens epidemiologically, we performed skin prick tests and RAST in 201 allergic patients from February, 1984 to February, 1985 and 339 patients from February, 1997 to February, 1998. Results: The Following results were obtained. 1) Total sensitization rates did not change significantly(74.2% vs 75.8%, p=0.664). 2) Positive reaction rates to pollens were similar(35.8% vs 30.1%, p=0.17). 3) Positive rates to HDM(house dust mite) were decreased(66.1% vs 56.3%, p=0.02). 4) Positive rates to fungi and animal danders were decreased significantly(p<0.001). Conclusion : Environmental allergens associated with hygine in Chonbuk provincial areas such as HDM and fungi are decreased significantly during 13 years.

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The hierarchical structures of cause-and-effect relationships on the profit factors in overseas construction projects (해외건설공사 수익성 영향인자의 계층구조 및 사레적용에 관한 연구)

  • Han, Seung-Heon;Sun, Seung-Min;Park, Sang-Hyuk;Jung, Do-Young
    • Korean Journal of Construction Engineering and Management
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    • v.7 no.5
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    • pp.64-76
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    • 2006
  • Korea's overseas construction industry has been rather depressed by the weakened profitability as well as the sharp decrease of the market shares due to the lack of international competitiveness and the declined international market. There exist a lot of various risks in performing the overseas construction, and especially EPC projects, which entail complicated process from different parts, also require a sophisticated procurement and management skill. Subsequently, to survive in the competitive international market, we need to establish strategies to select potentially profitable projects at the initial stage of bidding process and to mitigate the high degree of risk exposure through contract negotiation and its adjustment. This research discusses the trend of environment in international construction markets. Then, it identifies the key factors that affect the profitability significantly through the structured surveys from 59 actual overseas projects, and it analyzes the key factors by using statistical methods. This research provides the profitability evaluation bases, with which overseas construction participants can forecast and analyze the risk more systematically, by eliciting profit-influencing factors using the result of statistical analysis, literature review and structuring their cause-and-effect relationships. The profitability casual hierarchy structure describes the profitability factors' hierarchy in details and their interrelationships. It also enables us to find out critical factors directly related to profitability aggravation through a qualitative and quantitative analysis. Ultimately, with this hierarchy structure as the base, the research will suggest how to develop the quantitative profitability forecasting model.

Utilization of Sticky Traps to Increase the Efficiency of Pheromone Traps Against Riptortus clavatus (Hemiptera: Alydidae) (톱다리개미허리노린재 방제용 페로몬트랩의 효율증대를 위한 끈끈이트랩 활용)

  • Park, Bo-Sun;Cho, Jung-Lae;Sim, Chang-Ki;Yun, Ji-Yeong;Kim, Yong-Uk;Choe, Ho-Jeong;Park, Jong-Ho
    • Korean journal of applied entomology
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    • v.59 no.3
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    • pp.257-264
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    • 2020
  • The purpose of this study was to investigate the attraction distance range of pheromone traps used in the control of stink bugs, which are a problem in persimmon orchards, and the effects of sticky traps in increasing the efficiency of pheromone traps. Labeled individuals were released and then recaptured on pheromone and sticky traps. Riptortus clavatus was attracted to pheromone traps up to 60 m away. The capture rates of R. clavatus on sticky traps were 35%, 27%, 34%, 2.9%, and 0.6% after 0, 1, 2, 3, and 4 weeks To improve clarity, II have added this information from the details shown in the figures. Please check whether you agree.of exposure of the traps to the environment, respectively. Besides, when both pheromone and sticky traps were used at the same time following the release-recapture method, the capture rate of R. clavatus was 12 times higher than that by using pheromone traps only.

A Study on Development of Power Analysing Device for PV Module (태양전지 모듈의 발전량 분석 장치 개발에 관한 연구)

  • Moon, Chae-Joo;Kwak, Seung-Hun;Jang, Yeong-Hak;Kim, Tae-Gon;Kim, Eui-Sun;Kim, Tae-Hyun
    • Journal of the Korean Solar Energy Society
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    • v.30 no.6
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    • pp.73-80
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    • 2010
  • This study was conducted to estimate the relative performance of modules with changed characteristics due to long term exposure to the outdoor environment, with a specially made test device for simultaneous measurement of real time power output from the photovoltaic array, taking into account the inclined panel, direct irradiation, power being generated, temperature as well as the optimal analysis timing. In terminology description, M is an abbreviation of module and Group A, Group B are 10 modules series connection (1~10 of M), (11~20 of M) for each of them respectively. The overall mean voltage difference of M-18 with the lowest power output and M-14 with the highest output is-2.13V and it was identifiable that voltage difference was more concentrated to Group B. In addition, in case of M-2 and M-7, M-8, when compared with M-14, the overall mean voltage difference was -0.92V, -1.56 and -0.91V respectively showing the more concentration to Group A. When the temperature of module went up by $1^{\circ}C$, the mean voltage was reduced by 0.35V. For current, Group A was lower than Group B by-0.022A and the ratio of each group was 49.68% and 50.32% respectively, presumably the module with deteriorated properties were more concentrated to Group A relatively. From the comparison of relations with the comprehensive accumulation, M-2, M-7, M-8, M-16 and M-18 were those with deterioration of performance to the worst, thereby requiring precision examination. In comparative efficiency, M-14 was the most excellent one as 12.19% while M-18 as 10.53% was identified that its efficiency was comparatively rapidly reduced.

Decay Resistance and Effectiveness of CCA Preservative against Decay on the 4 Imported Softwoods (수입침엽수(輸入針葉樹) 4수종(樹種)의 내후성(耐朽性) 및 CCA계(系) 목재방부제(木材防腐劑) 처리(處理)에 따른 방부효과(防腐效果))

  • Lee, Jong Shin;Kim, Young Sik;Han, Kie Sun
    • Korean Journal of Agricultural Science
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    • v.22 no.1
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    • pp.42-48
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    • 1995
  • With the aim to investigation of decay resistance and optimum concentration in chrome-copper-arsenic(CCA) preservative treatment on the imported softwoods from Siberia and North america, preservative absorption after CCA impregnation, weight losses and degradation patterns by decay fungi were examined. The density and latewood rate of Siberia softwoods(Spruce and Larch) were higher than those of North america softwoods(Douglas-fir and Western hemlock), resulting in the decrease of the CCA preservative absorption in the Siberia softwoods. In the case of untreated softwoods, decay resistance against Coriolus versicolor was lower than against Tyromyces palustris. For CCA treated softwoods, preservative effectiveness increased with increase in concentration of CCA solution. When treated with 0.7% CCA solution, efficiency value was more than 80 and 90 for C. versicolor and T. palustris, respectively. From this results, in the CCA preservative treatment for imported softwoods, it can be concluded that optimum concentration of CCA solution is approximately 0.7%. The absorption of CCA preservative distributed in the range of 3.8 and $5.5kg/m^3$. After exposure to testing fungi, in the untreated softwoods, bore holes formed in the cell walls and bordered pits, moreover, bordered pit canals enlarged by the fungi. However, 0.5% CCA treated softwoods was almost no deterioration in the cell walls and bordered pits due to decay.

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Clinical Study on Mesothelioma of the Pleura (원발성 흉막중피종의 임상적 고찰)

  • Shim, Tae-Sun;Kim, Ho-Joong;Choe, Hyung-Seok;Lee, Hyuk-Pyo;Seo, Ji-Young;Kim, Young-Whan;Shim, Young-Soo;Kim, Keun-Youl;Han, Yong-Chol
    • Tuberculosis and Respiratory Diseases
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    • v.38 no.2
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    • pp.135-142
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    • 1991
  • We reviewed 15 cases of mesothelioma of the pleura, of which three cases were localized benign form and 12 cases were malignant diffuse form. The tumors were distributed equally in both sexes, and occured most commonly in fifth to seventh decades. The history of exposure to asbestos was present in only one case. The chief complaints were mainly chest pain and dyspnea. Associated symptoms were cough, sputum, hemoptysis, weight loss, anorexia, chill. On physical examination, unilateral, decreased breathing sound was main feature. The simple chest radiograph showed masses in all localized mesotheliomas (100%) and in 2 diffuse mesotheliomas (17%). 8 cases of diffuse mesotheliomas (67%) showed unilateral pleural effusions. Pleural effusions were mainly bloody (67%), and almost all were exudates. In all localized mesotheliomas, final diagnosis was made by open thoracotomy. In diffuse mesotheliomas, final diagnosis was made by open thoracotomy in 7 cases, chest wall mass biopsy in 2 cases, thoracoscopic biopsy in 1 case, pleural biopsy in 1 case, and pleural biopsy combined with axillary lymph node biopsy in 1 case. Localized mesotheliomas were treated by simple excision with good prognosis. In diffuse mesotheliomas, surgical treatment (pleuropneumonectomy, pleurectomy), chemotherapy, or radiotherapy, alone or in combination, were used with dismal prognosis. The prognostic factors were not found due to the small number of cases, incomplete follow up, and early drop out.

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Factors Affecting the Morbidity Related to Respiratory Dieseases in Urban Korea (한국 도시의 만성호흡기 질환 이환율에 영향을 주는 요인)

  • Han, Sung-Hyun;Park, Jae-Sung;Seo, Seung-Hee;Yoon, Jee-Eun;Jee, Sun-Ha
    • Korea journal of population studies
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    • v.28 no.2
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    • pp.205-217
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    • 2005
  • Purpose: To evaluate the factors affecting hospital utilization for respiratory diseases by ecological study design and GIS tool. To raise the social concern for respiratory disease by the result. Methods: Hospital admission data supported by national health insurance cooperation were transformed to spread sheet data format and combined with air monitoring dataset. Air pollution data were collected from the annual report of air monitoring published by Korea Ministry of Environment. Socioeconomic statistics including population density, age distribution, forest ratio etc.. were filed using Korea National Statistical Office database. Multiple linear regression analysis was performed to evaluate the factors affecting hospital utilization for respiratory diseases. Analytical unit was 52 cities. Results: The factors affecting hospital utilization for respiratory diseases were the proportion of population 60 years and over, seaside city, $O_3$ level, smoking rate. Conclusions: However, outdoor pollutants monitoring data and smoking rate have weakness in reflecting individual exposure. Further research is required to propose more illustrative means to evaluate causal relationship between air pollution and respiratory health effect factors.

The Association of Post-Storage Physiological Disorder Incidence with Respiration and Ethylene Production in 'Fuyu' Persimmon Fruits ('부유' 단감 과실에서 저장 후 생리적 장해 발생과 호흡 및 에틸렌 생성의 상호 관계)

  • Ahn, Gwang-Hwan;Song, Won-Doo;Choi, Seong-Jin;Lee, Dong-Sun
    • Korean Journal of Food Science and Technology
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    • v.36 no.2
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    • pp.283-287
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    • 2004
  • Persimmons suffer from such physiological disorders as flesh softening, peel blackening, and flesh browning, which occur rapidly particularly when exposed to ambient temperature after storage at low temperature, In this study causes of these disorders were examined in terms of respiration and ethylene production of the fruits. Jelly-like flesh softening, considered as symptom of chilling injury, rapidly developed within 3 days of exposure to ambient temperature without modified atmosphere (MA) packaging after low temperature storage. Disorder development was more suppressed at $30^{\circ}C$ than at $20^{\circ}C$; such temperature dependence is closely connected to ethylene production rate of fruits at both temperatures. Inhibition of ethylene production through MA packaging effectively reduced disorder development, which indicates ethylene production is closely related to jelly-like flesh softening disorder. Development of black-staining on peels occurs in fruits exposed directly to ambient temperature, but not in those packaged with thick PE-film. Flesh browning developed only under anaerobic respiration condition of high temperature and MA packaging with thick PE film, and occurred at quick reduction of available oxygen inside MA package at high temperature.

Flavonoid and Phenol Contents and Antioxidant Effect of Wine By-product Extracts (포도주 부산물의 총 플라보노이드와 총 페놀 함량 및 항산화 효과)

  • Baek, Jae Yeol;Lim, Sun-Young
    • Journal of Life Science
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    • v.26 no.8
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    • pp.948-954
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    • 2016
  • We investigated the flavonoid and phenol contents and antioxidant effect of wine by-product extract. Antioxidant effects were measured with 1,1-diphenyl-2-picryhydrazyl (DPPH) and 2.2'-azino-bis(3-ethylbenothiazoline-6-sulfonic acid) diammonium salt radical cation (ABTS+) assays. Cellular reactive oxygen species (ROS) were measured with the dichlorofluorescein-diacetate (DCFH-DA) assay. The flavonoid and phenol contents of the methanol (MeOH) extract were greater than those of the acetone+methylene chloride (A+M) extract. Among fractions, the 85% aqueous methanol (85% aq. MeOH) fraction contained the highest flavonoid contents, while the n-BuOH fraction had more phenol contents. In the DPPH and ABTS assays, the MeOH extract showed a scavenging effect greater than that of the A+M extract (p<0.05). The n-BuOH fraction (0.5 mg/ml concentrations) showed scavenging effects of 72% and 92%, respectively, in the DPPH and ABTS assays (p<0.05). However, the 85% aq. MeOH fraction showed a 90% scavenging effect in the DPPH assay only. In 120 min ROS production assay, all tested fractions dose-dependently decreased cellular ROS production induced by H2O2 in comparison with that produced by exposure to the extract-free control. The MeOH extract showed a higher sinhibitory effect on cellular ROS producing than that of the A+M extract at all concentrations tested. Treatment with the n-BuOH fraction (0.1 mg/ml concentrations) inhibited cellular ROS production by 60%. These results indicate that the n-BuOH fraction of wine by-product extract inhibited cellular oxidation and may contain valuable bioactive compounds such as flavonoids and phenols.