• Journal of Acupuncture Research
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• 제32권4호
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• pp.109-118
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• 2015

Objectives : The purpose of this study was to investigate the anti-oxidative effect of Suhwagije-decoction (SGT) pharmacopuncture solution on the liver and spleen cells of aged rats. Methods : The liver and spleen cells of 10, 52, and 72 week old Sprague Dawley (SD) rats were divided into three groups: distilled water (DW), Vit.C, and SGT groups, which were treated with DW, Vit.C and SGT pharmacopuncture solution respectively. The levels of superoxide dismutase (SOD), glutathione (GSH) and nitric oxide (NO) were then measured. Results : 1. Treatment of SGT pharmacopuncture solution significantly decreased NO concentration in spleen cells of 52 week old rats as compared with that of other groups. 2. Treatment of SGT pharmacopuncture solution significantly increased SOD activity in spleen cells of 72 week old rats as compared with that of other groups. Conclusions : Suhwagije-decoction (SGT) pharmacopuncture solution may have an anti-oxidative effect in the spleen cells of aged rats.

• 사상체질의학회지
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• 제23권3호
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• pp.374-390
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• 2011

1. Objectives: The purpose of this study is to investigate the effect of Suhwagije-tang(SGT) distillate on the immune activity of spleen cells of aged SD rats. 2. Methods: We used 10, 50, 72 weeks old SD rats in this study. Spleen cells from SD rats were stimulated with ConA and treated with 1% Vitamin C(Vit.C) or Suhwagijetang distillate(SGT). After 24 hours, the concentrations of IL-2, IL-4, IL-10, IFN-${\gamma}$ in the cell culture supernatant were measured by ELISA. 3. Results and Conclusions 1) At all concentration of SGT distillate, survival rates of liver cells were higher than the control group. In addition, 50% SGT distillate group's cell survival rates were significantly higher than other groups. 2) In 10 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group, Vit.C group. In 52 weeks SD rats(SGT group), the concentration of IL-2 significantly decreased in comparison with ConA group. 3) In 10, 52 weeks SD rats(SGT group), the concentration of IL-4 significantly decreased in comparison with ConA group. 4) In 10 weeks SD rats(SGT group), the concentration of IL-10 significantly decreased in comparison with ConA group. And in 72 weeks SD rats(SGT group), the concentration of IL-10 significantly increased in comparison with Vit.C group. 5) In 52, 72 weeks SD rats(SGT group), the concentration of IFN-${\gamma}$ significantly decreased in comparison with 10 weeks SD rats(SGT group). These results suggest that Suhwagije-tang(SGT) distillate has the effect of increasing the immune activity of spleen cells of aged SD rats.

• 사상체질의학회지
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• 제22권4호
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• pp.85-97
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• 2010

1. Objectives The purpose of this study is to investigate the effects of oral administration of distilled Suhwagije-tang in aging rats. 2. Methods The SD rats used in this experiment were 6, 48 and 68 weeks old. These groups were treated with distilled water(DW), 1% Vitamin C(Vit. C) and 50% Suhwagije-tang(SGT) distillate respectively, once a day for 4 weeks. Blood samples were taken from heart and the levels of various parameters in serum were analysed. 3. Results and Conclusions (1) At all concentration of SGT, survival rates of liver cells were higher than the control group. (2) The rate of which the 10W-SGT group gained weight was significantly higher than that of the control groups. (3) The levels of albumin in serum of 10W-SGT group were significantly increased in comparison to those of the DW group. The levels of ALP, total cholesterol and HDL-cholesterol in serum of 52W-SGT group were significantly decreased in comparison to those of the DW group. (4) The levels of testosterone in serum of SGT groups showed no significantly changes in comparison to those of the control groups. Testosterone levels were naturally decreased with advancing years, so 72W-DW group's testosterone level was significantly decreased in comparison to those of 10W-DW group's. In contrast, 72W-SGT group's level was the highest in comparison to those of the control groups and those of deviation from 10W, 52W and 72W in SGT groups was also smaller than control groups'. (5) The levels of glucose, total-bilirubin, ALT, AST, BUN, CRP, hs-CRP, homocystein, Na, K, Na/K ratio, Cl and Ca in serum of SGT groups showed no significantly changes in comparison to those of the control groups. These results suggest that oral administration of Suhwagije-tang distillate should be effective in promoting growth and preventing rapid decline of testosterone in aging rats does not cause any imbalance in liver, kidney and electrolyte.

• 한국철학논집
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• 제53호
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• pp.215-254
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• 2017

역학에서 호체는 괘의 구성 및 경문해석에 있어서 긴요한 역할을 한다. 그러나 호체에 대한 연구나 그 활용도에 대한 인식은 박약한 것이 현실이다. 본 논문은 본괘와 호체 그리고 호체의 호체(호호체)사이에 이어지는 연관성을 규명함으로써 역의 구성과 해석에 있어서 호체가 갖는 중요성을 재조명하고자 한다. 64괘는 16개의 호체로, 16개의 호체는 4개의 호체로 모인다. 4개의 호체는 중천건 중지곤 수화기제 화수미제가 된다. 즉 본괘의 호체로 성립된 6획괘에서 다시 호체를 추출하여 6획괘를 만들면 건 곤 기제 미제 4개의 괘로 수렴된다는 것이다. 본고에서는 호체의 호체를 호호체라 명명하고 이 호호체 4개 괘와 그에 각각 소속되어 있는 호체 및 본괘는 그 의미 해석에 있어서 일정한 연관이 있음을 주장하고자 한다. 본고는 호호체의 "단전"과 "대상전"을 중심으로 그 소속된 호체 및 본괘의 공통적인 의미를 드러내었다. 중천건과 중지곤은 호호체 호체 본괘에 모두 존재하므로 본호체(本互體)라 명명하였고 수화기제와 화수미제는 상대에 근원을 두고 있으므로 피호체(彼互體)라 명명하였다. 그 외의 호체(互體)들은 호체라 명명하였다. 호호체 중천건은 본호체 중천건을 비롯하여 택천쾌 천풍구 택풍대과 4개의 호체를 두었으며 이 4개의 호체는 열여섯 개의 본괘와 함께 중천건의 "단전(彖傳)" 중 만물이 바탕 하여 비롯되는[만물자시(萬物資始)] 위대한 시작[대시(大始)]에 참여하고 있다. 호호체 중지곤은 본호체 중지곤을 비롯하여 산지박 지뢰복 산뢰이 4개의 호체를 두었으며 이 4개의 호체는 16개의 본괘와 함께 중지곤의 "단전" 중 만물이 바탕하여 생하며[만물자생(萬物資生)] 만물을 이룸에 참여하고 있다. 호호체 수화기제는 피호체 화수미제를 비롯하여 화택규 뇌택귀매 뇌수해 4개의 호체를 두었으며 이 4개의 호체는 16개의 본괘와 함께 수화기제의 "단전" 중 '초길(初吉). 종지즉란(終止則亂)'이란 의미대로 처음에는 길(吉) 하지만 나중은 어지러워짐을 알려주고 있다. 호호체 화수미제는 피호체 수화기제를 비롯하여 풍화가인 풍산점 수산건 4개의 호체를 두었으며 이 4개의 호체는 16개의 본괘와 함께 화수미제 "단전"의 의미를 공유하고 있다. 즉 '가운데를 지났으니 돌아올 수 없다[미출중야(未出中也)].' '계속하여 끝마치지 못하기 때문이니 비록 자리가 마땅하지 않지만, 굳센 양과 부드러운 음이 호응한다[불속종야(不續終也) 수불당위(雖不當位) 강유응야(剛柔應也)].'는 의미대로, 계속하여 끝나지 않은 채 맞지 않는 것들끼리 묶여서 끝없이 이어지는 인간의 삶이 내재(內在)되어 있다. "주역"은 중천건 중지곤으로 시작하여 수화기제 화수미제로 끝난다. 64괘의 호호체가 이 4괘로 귀결된다는 것은 이 4괘가 시작과 마침을 주관하며 그 사이의 모든 괘들은 이 4괘의 범주 속에서 작용함을 보여주는 것이라 할 것이다. 호호체 "단전"과 "대상전"의 내용은 호호체로 귀속되는 호체 및 본괘를 해석함에 있어서 일정한 의미상 연관성을 지니며 그 해석의 방향성을 가리킨다고 생각된다. 이는 호체를 "주역" 괘 성립의 핵심적 원리로 조명해 볼 수 있는 여지를 열어주며, 동시에 호체가 주역해석에 있어서 중요한 의미를 지니고 있음을 시사하는 것이다.

• 사상체질의학회지
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• 제34권4호
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• pp.1-12
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• 2022

Objectives This paper investigates the origins, changes, and the constructive principles of Hyungbangjihwang-tang(荊防地黃湯). Methods Hyungbangjihwang-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Gogeumuigam(古今醫鑑)』, 『Sanghannon(傷寒論)』, 『Uihagjeongjeon(醫學正傳)』, 『Donguisusebowon·Sasangchobongwon(東醫壽世保元·四象草本卷)』, 『Donguisusebowon·Gabobon(東醫壽世保元·甲午本)』, 『Donguisusebowon·Sinchukbon(東醫壽世保元·辛丑本)』. Results and Conclusions The origins of Hyungbangjihwang-tang can be seen in three sections depending on the classification of medicinal herbs. Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風), Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), and Plantago asiatica L.(車前子) originated from Hyungbangpaedok-san(荊防敗毒散) included in 『Gogeumuigam』. Poria cocos Wolf.(茯苓) and Alisma canaliculatum(澤瀉) originated from Ohryoung-san(五苓散) included in 『Sanghannon』. Rehmannia glutinosa for hueichingensis(熟地黃) and Cornus officinalis S. et Z.(⼭茱萸) originated from Yukmijihwang-tang(六味地黃湯) included in 『Uihagjeongjeon』. Hyungbangpaedok-san was transformed into "Paedok-san" in 『Chobongwon(草本卷)』, Hyungbangpaedok-san in the 『Gabobon(甲午本)』 and 『Sinchukbon(辛丑本)』. Yukmijihwang-tang was mentioned as a Soyangin medicine in the 『Chobongwon』 and was later transformed into a Suhwagije-tang(水火旣濟湯) in 『Gabobon』. The meaning of Yukmijihwang-tang inherited in 『Sinchukbon』 as Dokhwaljihwang-tang and Hyungbangjihwang-tang. The medicinal herbs in Hyungbangjihwang-tang can be categorized in three sections by their functions, Schizonepeta tenuifolia Briq., Saposhnikovia divaricata Schischk., Notopterygium incisum Ting, Aralia cordata Thunb., and Plantago asiatica L. scatter the Pyohan(表寒) and make the Pyoeum(表陰) drop. Poria cocos Wolf.(茯苓) and Alisma canaliculatum(澤瀉) make the Pyoeum(表陰) drop through Lee-su(利水). Rehmannia glutinosa for hueichingensis(熟地黃) and Cornus officinalis S. et Z.(⼭茱萸) tonify Shin-won(腎元). The each principles of medicinal herbs corresponds to the stage of the "Cold-related Diarrhea in Soyangin Spleen Cold-based Exterior Cold disease(少陽人 脾受寒表寒病 亡陰病 身寒腹痛亡陰證)".