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http://dx.doi.org/10.13045/acupunct.2015066

The Anti-Oxidative Effect of Suhwagije-decoction on the Liver and Spleen Cells of Aged Rats  

Jeon, Jong Ik (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University)
Lee, Hyun Jin (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University)
Kim, Il Gu (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University)
Yim, Yun Kyoung (Department of Meridian & Acupoint, College of Korean Medicine, Daejeon University)
Publication Information
Journal of Acupuncture Research / v.32, no.4, 2015 , pp. 109-118 More about this Journal
Abstract
Objectives : The purpose of this study was to investigate the anti-oxidative effect of Suhwagije-decoction (SGT) pharmacopuncture solution on the liver and spleen cells of aged rats. Methods : The liver and spleen cells of 10, 52, and 72 week old Sprague Dawley (SD) rats were divided into three groups: distilled water (DW), Vit.C, and SGT groups, which were treated with DW, Vit.C and SGT pharmacopuncture solution respectively. The levels of superoxide dismutase (SOD), glutathione (GSH) and nitric oxide (NO) were then measured. Results : 1. Treatment of SGT pharmacopuncture solution significantly decreased NO concentration in spleen cells of 52 week old rats as compared with that of other groups. 2. Treatment of SGT pharmacopuncture solution significantly increased SOD activity in spleen cells of 72 week old rats as compared with that of other groups. Conclusions : Suhwagije-decoction (SGT) pharmacopuncture solution may have an anti-oxidative effect in the spleen cells of aged rats.
Keywords
Suhwagije-decoction; Anti-oxidative effect; Spleen cells; Aged rats;
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Times Cited By KSCI : 7  (Citation Analysis)
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