• 생물환경조절학회지
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• 제6권1호
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• pp.55-65
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• 1997

본 연구는 육묘용 로봇 이식기를 개발하기 위한 목적으로 수행되었으며 그 결과는 다음과 같다. 1. 기계시각에 의한 결주 및 불량묘 판별은 72공 플러그묘판의 경우 98.8%, 128공의 플러그묘판의 경우 94.9%, 잎의 방향을 고려한 경우 72공의 플러그묘판의 경우 93.5%, 128공의 경우 91.0%의 정확도를 나타내었다. 2. 로봇 이식기의 기구부와 구동부를 개발하였고, 이를 제어하기 위한 제어기를 개발하였으며, 머니플레이터의 위치제어 정확도는 $\pm$ 1mm로 나타났다. 3. 잎의 방향을 고려하지 않은 이식방법에서의 이식성공률은 72공 플러그묘판의 경우 95.5%, 128공의 플러그묘판의 경우 94.5%로 나타났으며, 잎의 방향을 고려한 이식방법에서의 이식성공률은 72공의 경우 96.0%, 128공의 경우 95.0%로 나타났다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제22권1호
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• pp.39-47
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• 2022

Background: This was a randomized controlled clinical trial that aimed to evaluate the anesthetic efficacy of 2% lidocaine combined with different concentrations of epinephrine (plain, 1:200,000 and 1:80,000) during endodontic treatment of maxillary molars with symptomatic irreversible pulpitis. Methods: The trial included 144 adult patients who were randomly allocated to three treatment groups. All patients received buccal-plus-palatal infiltration. After 10 min, pulp sensibility testing was performed using an electric pulp test (EPT). If a tooth responded positively, anesthesia was considered to have failed. In the case of a negative EPT response, endodontic access was initiated under rubber dam isolation. The success of anesthesia was defined as having a pain score less than 55 on the Heft Parker visual analog scale (HP VAS), which was categorized as 'no pain' or 'faint/weak/mild' pain on the HP VAS. Baseline pre-injection and post-injection maximum heart rates were recorded. The Pearson chi-square test was used to analyze the anesthetic success rates at 5% significance. Results: Plain 2% lidocaine and 2% lidocaine with 1:200,000 epinephrine and 1:80,000 epinephrine had anesthetic success rates of 18.75%, 72.9%, and 82.3%, respectively. Statistical analysis indicated significant differences between the groups (P < 0.001, 𝛘² = 47.5, df = 2). The maximum heart rate increase was seen with 2% lidocaine solution with epinephrine. Conclusion: Adding epinephrine to 2% lidocaine significantly improves its anesthetic success rates during the root canal treatment of maxillary molars with symptomatic irreversible pulpitis.

• 대한소아치과학회지
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• 제44권1호
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• pp.47-55
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• 2017

본 연구의 목적은 괴사된 미성숙 영구치의 재생근관치료 시 성공에 영향을 미치는 결정적 인자를 평가하고자 함에 있다. 미성숙 영구치의 치수괴사로 진단된 환자 중 재생근관치료를 시행하고 1년 이상 경과 관찰한 증례로서 46개 치아가 선택되었다. 이를 대상으로 성공률과 관련된 변수로서 나이, 성별, 초진 시 치근발육단계, 치수괴사 원인, 치료과정, 임상 및 방사선학적 결과를 조사하고 관련성을 통계 분석하였다. 분석 결과, 치근발육단계는 재생근관치료의 성공률에 영향을 미치지 않았으나, 치수괴사 원인은 치외치, 우식, 외상 순으로 성공률이 높았으며 유의한 차이가 있었다. 근관내 멸균 시 국소적 항생제를 적용했을 때 높은 성공률을 보이며 통계학적 유의차를 보였으며, double과 triple antibiotic paste간에는 유의차가 없었다. 재생근관치료의 성공률을 높이기 위해 치수 괴사 원인, 특히 외상 증례에 있어 신중한 적응증 판단이 선행되어야 하며, 적절한 항생제 적용이 필요하다.

• Advances in pediatric surgery
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• 제16권2호
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• pp.108-116
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• 2010

Air reduction is a safe, effective, and fast initial treatment for pediatric intussusception. There is low dose radiation exposure. Factors affecting outcomes of air reduction were analyzed by reviewing the clinical features and results of treatment. A total of 399 out of 485 patients with pediatric intussusceptions were treated at the Seoul National University Children's Hospital from 1996 to 2009. All of the patients received air reduction as the first line of treatment. Clinical features such as gender, age, seasonal variation, symptoms, signs, types, pathologic leading point, and treatment results including success rate, complication, recurrence, NPO time, and duration of hospitalization were reviewed. The Pearson chi-square, student T-, and logistic regression tests were used for statistical analysis. P-value less than 0.05 was considered to be statistically significant. The prevalent clinical features were: male (65.4 %), under one-year of age (40.3 %), ileocolic type (71.9 %), abdominal pain (85.4 %), and accompanying mesentery lymph node enlargement (2.2 %). The overall success rate for air reduction was 78.4 % (313 of 399 patients), and the perforation rate during reduction was 1.5 %. There were 23 recurrent cases over 21.6 months. All were successfully treated with re-do air reduction. Reduction failures had longer overall NPO times (27.067hrs vs. 43.0588hrs; p=0.000) and hospitalization durations (1.738d vs. 6.975d; p=0.000) compared to the successful cases. The factors affecting success rates were fever (p=0.002), abdominal distension (p=0.000), lethargy (p=0.000) and symptom duration (p=0.000) on univariate analysis. Failure rates were higher in patients with symptom durations greater than 24 hours (p=0.023), and lethargy (p=0.003) on multivariate analysis. Air reduction showed high success rates and excellent treatment outcomes as the initial treatment for pediatric intussusception in this study. Symptom duration and lethargy were significantly associated with reduced success rates.

• 대한소아치과학회지
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• 제44권3호
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• pp.317-326
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• 2017

이 연구의 목적은 인위적으로 형성된 수여부에 자가이식한 상악 견치의 생존율과 성공률에 대해 알아보고 성공적인 이식에 영향을 주는 요인에 대해 분석하는 것이다. 28명 남녀 어린이의 37개의 자가이식한 상악 견치에 대해 후향적으로 조사하였으며 평균 관찰 기간은 25.1개월이었다. 임상 및 방사선적 평가를 통해 동요도, 병적인 치근 흡수, 수직적 치조골소실 그리고 유착에 대해 조사하였다. 관찰 기간 동안 100%의 생존을 보였으나 13개의 치아가 실패로 분류되어 64.9%의 성공률을 보였다. Cox 비례위험모형에서 성공률에 영향을 주는 요인은 공여치아의 치낭의 비후로 나타났다. 이 연구는 임상가들에게 자가치아이식 시 인위적으로 치조와를 형성할 경우 예후를 판단하는 지침이 될 수 있다고 생각된다.

• Journal of Oral Medicine and Pain
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• 제44권3호
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• pp.77-82
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• 2019

Purpose: With the popularity of implant therapy, clinicians need to know about treating the dental implant in patients with gingival involvement of oral lichen planus (OLP). The aim of this study is to evaluate the survival and success rates of dental implant and propose of clinical guidelines for implant treatment in OLP patient with gingival involvement. Methods: A literature search was performed in PubMed/Medline, and Cochrane database. Papers in English language published between 1990 and 2019 were evaluated. The focused questions were following; 1) Dose gingival OLP affect the survival and success rates of dental implants? 2) The management of OLP patients with gingival involvement receiving dental implant. Results: There was no study about the evaluation of dental implant only in gingival OLP patient. Five studies evaluating dental implants in OLP patients were included in this review. Implant survival rate was 100.0% in well-controlled OLP patients in all included studies. The use of topical/systemic corticosteroid in OLP patients was performed before and/or after implant placement in all included studies. Conclusions: The implant survival and success rates in well-controlled OLP patients did not different from that of non-OLP healthy subjects. The gingival OLP is associated with higher rate of peri-implant mucositis. Adequate management of gingival OLP lesions before and after implant insertion is required to reduce inflammation and associated bone loss.

• 지식경영연구
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• 제11권1호
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• pp.37-50
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• 2010

Bioharmaceutical technologies have consistently been areas in which large licensing agreements have been negotiated. However, there are very limited informations in the open literature on how its running royalty rates are determined and no specific methods are yet provided. The purpose of this study is to suggest an appropriate method for the estimation of running royalty of bioharmaceutical technology in licensing agreements. Here distribution of risk-adjusted operating margins are obtained by simulation using statistics of success rates in the stage of clinical trials and profit margins. Three factors based on technology, business and license legal terms are considered and combined as licensing competitiveness level. Finally, reasonable running royalty is estimated by combining simulated distribution and licensing competitiveness level. This suggested method is expected to practically useful for licensor to establish an appropriate running royalty rate for licensing.

• Restorative Dentistry and Endodontics
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• 제40권4호
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• pp.276-285
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• 2015

Objectives: The purpose of this study was to evaluate the efficacy of mineral trioxide aggregate (MTA), Biodentine and Propolis as pulpotomy medicaments in primary dentition, both clinically and radiographically. Materials and Methods: A total of 75 healthy 3 to 10 yr old children each having at least one carious primary molar tooth were selected. Random assignment of the pulpotomy medicaments was done as follows: Group I, MTA; Group II, Biodentine; Group III, Propolis. All the pulpotomized teeth were evaluated at 3, 6, and 9 mon clinically and radiographically, based on the scoring criteria system. Results: The clinical success rates were found to be similar among the three groups at 3 and 6 mon where as a significant decrease in success rate was observed in Group III (84%) compared to both Group I (100%) and Group II (100%) at 9 mon. Radiographic success rates over a period of 9 mon in Groups I, II, and III were 92, 80, and 72%, respectively. Conclusions: Teeth treated with MTA and Biodentine showed more favorable clinical and radiographic success as compared to Propolis at 9 mon follow-up.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권1호
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• pp.41-46
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• 2018

Background: The purpose of this prospective randomized single-blind clinical trial was to evaluate the effect of tilting the head on the anesthetic efficacy of inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis. Methods: Ninety-two patients were divided into two groups: the first group received IANB and the head was tilted in the direction of the block for 15 min, whereas the second group received IANB and the head was tilted to the opposite side. Access cavity preparation was initiated after 15 min. Success was defined as no pain or faint/weak/mild pain during endodontic access preparation and instrumentation. The anesthetic success rates were analyzed by Pearson chi-square test at 5% significance levels. Results: The same side position and opposite side position yielded 41% and 30% anesthetic success rates, respectively; there was no significant difference between the two sides. Conclusions: Relative head position has no effect on the anesthetic success rate of IANB.

• 대한치과보철학회지
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• 제55권1호
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• pp.26-31
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• 2017

목적: 지르코니아 프레임워크를 이용한 시멘트 유지형 임플란트-지지 단일 크라운과 연결 크라운의 성공률과 보철적 합병증을 임상적으로 평가하는 것이다. 대상 및 방법: 67명의 환자에서 75개 수복물(단일 51개, 연결 24개)을 지르코니아 프레임워크를 이용한 시멘트 유지형 임플란트-지지 단일 크라운 혹은 연결 크라운으로 수복했다. 모든 수복물은 임시 시멘트로 합착했다. 보철적 합병증과 성공률을 조사하고, 나이, 성별, 보철물의 위치, 대합치, 보철물의 유형이 보철적 합병증에 미치는 영향을 평가했다. 결과:평균 22.2개월의 관찰 결과, 최종 누적 성공률은 66.9 (73.2 - 60.6)%였다. 유지 상실이 16개 보철물(단일 14개, 연결 2개)에서 나타났고, 지대주 나사 풀림과 비니어 도재 파절은 단일 크라운에서만 각각 2개의 보철물에서 나타났다. 단일 크라운과 연결 크라운에 대한 Kaplan-Meier 생존분석 결과, 최종 누적 성공률은 각각 58.9 (66.6 - 51.2)%, 87.5 (96.1 - 78.9)%를 보여 통계적으로 유의한 차이가 있었지만, 다른 고려 요인들은 보철적 합병증에 통계적으로 유의성이 없었다. 결론: 보철적 합병증은 유지 상실이 가장 많았고, 지대주 나사 풀림 및 비니어 도재 파절은 단일 크라운에서만 비교적 적게 관찰되었다. 나이, 성별, 보철물의 위치, 대합치에 따른 보철적 합병증에 미치는 영향은 유의한 차이가 없었지만, 상부 보철물을 연결 크라운으로 제작했을 때, 단일 크라운으로 제작한 경우보다 높은 성공률을 보였다.