• Korean Parent-Child Health Journal
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• v.11 no.2
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• pp.115-126
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• 2008

Purpose: The purpose of this study was to identify the knowledge, attitude and experience of elementary students on smoking. Method: This study is a descriptive survey study by a self reported questionnaires and the subjects of this study were 631 students who are attending elementary schools in Seoul. Results: The results of this study are as followed : 1) 67.9% of subjects have smoking family members, 91.9% of subjects don't have good relation to their parents, 78.6% of subjects have discontented school life and 4.6% of subjects are smoking now. 2) 37.9% of subjects hardly ever experienced education of substance use. There are only 10~17% of subjects have experienced education of substance use among 3~4th grade students. 3) There is highly right answer rate in "relation between pregnant women and fetus(91.6)", "addiction of smoking((85.6%)" and "earlier smoking stronger addiction(72.9%)". 4) The attitude of smoking is mostly negative, and 3.1% of subjects have future smoking plan. 5) The subjects who have smoking parents more have future smoking plan(t=-2.28, p=.02), more positive attitude for smoking(t=-4.42, p=.00). Conclusion: There is needed systematic smoking prevention program for elementary students which fits their knowledge and attitude not later than 3rd. grade, and continual smoking prevention program for adulthood.

• Microbiology and Biotechnology Letters
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• v.36 no.4
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• pp.285-290
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• 2008

Rahnella aquatilis strain AY2000 produces an anti-yeast substance (AYS), however activity of the AYS has a declining tendency during storage. To investigate what has been decreased activity of the AYS, the AYS was treated with various physicochemical agents in this paper. The activity of AYS was decreased by heat treatment. Thiol reagent such as $\beta$-mercaptoethanol or dithiothreitol was also another factor decreasing the activity of AYS. However, pH, EDTA, and NaCl were not factors decreasing the activity of AYS. Use of methanol to precipitate the AYS was also decreased the activity of AYS. The activity of AYS was not lost after Sepharose S-400 gel filtration. However, the AYS activity was completely lost, when a polysaccharide and a unknown substance (230 nm absorption) among components of the AYS was separated by DEAE-cellulose chromatography. MIC of the AYS against S. cerevisiae was usually determined at $7.8-15.6{\mu}g/ml$.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.353-353
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• 2009

It is an important task to construct a recycling society with a low damage on the environment in our century. Magnetic separation is expected to be applied for the industrial waste treatment as an important supporting technology. In the magnetic separation of dry condition, the cohesive force between particles is strong compared with that in the wet condition's magnetic separation. The use of high magnetic field by the superconducting magnet enhances the powder's magnetic substance capture ability of the magnetic separation. In this study, the POSCO's coolant sludge of hot rolled steel was used for the superconducting magnetic separation of dry condition. Cryo-cooled NB-Ti superconducting magnet with 100 mm room temperature bore and 600 mm of height was used for magnetic separator.

• Journal of Biomedical Engineering Research
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• v.38 no.5
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• pp.242-247
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• 2017

This study presents a bio-chemical energy harvesting system which can generate electric power from bioorganic substance contained in vermicompost. It produced electricity by inoculating microbial fuel cell(MFC) with earthworm-composted food waste. The generated electricity was converted into usable voltage level for mobile electronics through power conditioning circuits. The implemented prototype showed $200{\mu}W$ of maximum output electric power, which successfully supplied a beacon device which continuously transmitted data to nearby smartphone without a battery. The proposed system can help develop portable or bio-mimetic energy supply for sustainable use with further improvement.

• 제어로봇시스템학회:학술대회논문집
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• 1990.10a
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• pp.602-607
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• 1990

Spent nuclear fuel is very dangerous substance emitting strong ionizing radiation which is harmful to human body. The remote handling of spent nuclear fuel is essential because people cannot access this substance without protecting radiation. To handle highly radioactive material or nuclear waste, many kinds of teleoperators such as master slave manipulator, electro mechanical manipulator, servo manipulator, mobile robot was developed. The distance and dimension of target object cannot be measured easily when highly radioactive material is handled by teleoperator because one should use lead glass or TV camera and monitor to protect radiation and see target object. During experiments on the remote handling of spent nuclear fuel by electro mechanical manipulator, we often felt that a distance and dimension measurement system is necessary to handle the objects which is in the highly radioactive environment, so we developed a system which is appropriate for this purpose.

• KIEAE Journal
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• v.4 no.4
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• pp.3-10
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• 2004

If move in in the new apartment usually, do that hundreds hazardous substance among air floats and is broken-down. In the case of the floor, organic compound turns in adhesives that is bitter when attach the reinforcement floor and material lumber and hazardous substance is exhausted much wallpaper and concrete. Therefore, to reveal maximum this research to apply on interior of building to live function of charcoal, at non combustible material two faces that can promise safety from fire, strong and satisfy light performance, and it is thing about development of sheathing that use recycling material for barren land of multi-function and surface treatment of charcoal board as well as can keep healthy indoor environment.

• Journal of Korean Academy of Nursing
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• v.49 no.6
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• pp.701-712
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• 2019

Purpose: Despite the high drinking rates and the complexity of drinking behaviors in adolescents, insufficient attention has been paid to their drinking patterns. Therefore, we aimed to identify patterns of adolescent drinking behaviors and factors predicting the distinct subgroups of adolescent drinking behaviors. Methods: We analyzed nationally representative secondary data obtained in 2017. Our final sample included 24,417 Korean adolescents who had consumed at least one glass of alcohol in their lifetime. To investigate patterns of drinking behaviors, we conducted a latent class analysis using nine alcohol-related characteristics, including alcohol consumption levels, solitary drinking, timing of drinking initiation, and negative consequences of drinking. Furthermore, we investigated differences in demographics, mental health status, and characteristics of substance use across the latent classes identified in our study. To do so, we used the PROC LCA with COVARIATES statement in the SAS software. Results: We identified three latent classes of drinking behaviors: current non-drinkers (CND), binge drinkers (BD), and problem drinkers (PD). Compared to the CND class, both BD and PD classes were strongly associated with higher academic year, lower academic performance, higher levels of stress, suicidal ideation, lifetime conventional or electronic cigarette use, and lifetime use of other drugs. Conclusion: Health professionals should develop and implement intervention strategies targeting individual subgroups of drinking behaviors to obtain better outcomes. In particular, health professionals should consider different characteristics across subgroups of adolescent drinking behaviors when developing the interventions, such as poor mental health status and other substance use among binge and problem drinkers.

• Journal of Dairy Science and Biotechnology
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• v.34 no.2
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• pp.99-116
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• 2016

We herein performed animal safety assessment in accordance with Good Laboratory Practice (GLP) regulations with the aim of developing sialic acid from glycomacropeptide (hereafter referred to as "GMP") as an index ingredient and functional component in functional foods. GMP is a type of whey protein derived from milk and a safe food, with multiple functions, such as antiviral activity. A test substance was produced containing 7% (w/w) sialic acid and mostly-hydrolyzed whey protein (hereafter referred to as "7%-GNANA") by enzymatic treatment of substrate GMP. The maximum intake test dose level was selected based on 5,000 mg/kg/day dose set for male NOEL (no-observed-effect-level) and female NOAEL (no-observed-adverse-effect-level) determined by a dose-range finding (DRF) test (GLP Center of Catholic University of Daegu, Report No. 15-NREO-001) that was previously conducted with the same test substance. To evaluate the toxicity of a repeated oral dose of the test substance in connection with the previous DRF study, 1,250, 2,500, and 5,000 mg/kg of the substance were administered by a probe into the stomachs of 6-week-old SPF Sprague-Dawley male and female rats for 90 d. Each test group consisted of 10 male and 10 female rats. To determine the toxicity index, all parameters, such as observation of common signs; measurements of body weight and food consumption; ophthalmic examination; urinalysis, electrolyte, hematological, and serum biochemical examination; measurement of organ weights during autopsy; and visual and histopathological examinations were conducted according to GLP standards. After evaluating the results based on the test toxicity assessment criteria, it was determined that NOAEL of the test substance, 7%-GNANA, was 5,000 mg/kg/day, for both male and female rats. No animal death was noted in any of the test groups, including the control group, during the study period, and there was no significant difference associated with test substance, as compared with the control group, with respect to general symptoms, body weight changes, food consumption, ophthalmic examination, urinalysis, hematological and serum biochemical examination, and electrolyte and blood coagulation tests during the administration period (P<0.05). As assessed by the effects of the test substance on organ weights, food consumption, autopsy, and histopathological safety, change in kidney weight as an indicator of male NOAEL revealed up to 20% kidney weight increase in the high-dose group (5,000 mg/kg/day) compared with the change in the control group. However, it was concluded that this effect of the test substance was minor. In the case of female rats, reduction of food consumption, increase of kidney weight, and decrease of thymus weight were observed in the high-dose group. The kidney weight increased by 10.2% (left) and 8.9% (right) in the high-dose group, with a slight dose-dependency compared with that of the control group. It was observed that the thymus weight decreased by 25.3% in the high-dose group, but it was a minor test substance-associated effect. During the autopsy, botryoid tumor was detected on the ribs of one subject in the high-dose group, but we concluded that the tumor has been caused by a naturally occurring (non-test) substance. Histopathological examination revealed lesions on the kidney, liver, spleen, and other organs in the low-dose test group. Since these lesions were considered a separate phenomenon, or naturally occurring and associated with aging, it was checked whether any target organ showed clear symptoms caused by the test substance. In conclusion, different concentrations of the test substance were fed to rats and, consequently, it was verified that only a minor effect was associated with the test substance in the high-dose (5,000 mg/kg/day) group of both male and female rats, without any other significant effects associated with the test substance. Therefore, it was concluded that NOAEL of 7%-GNANA (product name: Helicobactrol) with male and female rats as test animals was 5,000 mg/kg/day, and it thus was determined that the substance is safe for the ultimate use as an ingredient of health functional foods.

• Anxiety and mood
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• v.1 no.1
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• pp.31-36
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• 2005

Benzodiazepine (BDZ) has the possibilities of development of tolerance, withdrawal symptoms, and abuse/addiction, as well as chronically adverse effects. Although many guidelines have proposed the restricted prescription of them, their uses in many psychiatric areas as well as primary practice are still wide spread. So we tried to reappraise the clinical characteristics of BDZ and then to consider the appropriate use. Firstly, meta-analyses on long-term use of BDZ indicated the cognitive impairment, which could be improved after discontinuation of BDZ. Next, there have been some evidences that the long-term use of BDZ does not develop tolerance, contrary to our concern, and maintains good anxiolytic effects. Also, physiological dependence should be discriminated from abuse/addiction, assuming the reality that the risk of BDZ abuse/addiction is surely overestimated. These issues are discussed in detail.

• Korean Journal of Health Education and Promotion
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• v.18 no.2
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• pp.129-140
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• 2001

Harmful environment around school area have been increased with socio-economic development in Korea. Those entertainment facilities have caused a negative effect on the learning environment in many schools. As a result of increased entertainment harmful facilities in school area, the numbers of deviant behaviors such as drinking, smoking, substance abuse and sexual activity among junior high school students have been significantly increased. Given this situation, the aim of this study was to describe the distribution of the facilities; to access applied(experience) of the facilities according to students demographic variables; and to identify the relationship between use of the facilities and students risk health behaviors such as smoking, drinking, substance abuse and sexual activity. The field theory was used to study the relationship between the use of the facilities and risk health behaviors among students. A self-administered questionnaire survey was conducted in Korea. 2,114 junior and senior high school students(middle and high school students) were recruited by the method of proportional stratified random sampling from June to July 2000. Results indicated that: 1) The rates of using game centers, PC rooms, Song rooms and comic rooms were 78.3%, 75.6%, 71.6%, and 34.3% respectively. 2) High school students visited the entertainment facilities significantly more than middle school students(p〈0.001). 3) The rates of using facilities near schools were significantly associated with parents job(p〈0.05). 4) The rates of drinking, smoking, drug abuse, and sexual activity were 21.6%, 11.9%, 4.3% and 1.6% respectively. 5) Risk health behaviors such as smoking(p〈0.001) and drinking(p〈0.001), amount of smoking and drinking(p〈0.001) and sexual activity(p〈0.05) were associated with the experience of using the facilities. Those who had drinking experience were more likely to go the facilities than those without drinking experience. Also, those who were smoker had higher probability of going using the facilities than non-smokers.