• 식품과학과 산업
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• 제50권1호
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• pp.67-73
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• 2017

Control of food pathogens is critical in food safety field. Norovirus is one of the major causes of gastroenteritis and food poisoning worldwide, however, currently, there is not a vaccine or a specific drug available for its treatment. There are several methods to inactivate norovirus during food processing by chemical and physical treatments, however, the use of natural substance has been suggested as an optional strategy due to their safety and consumer preference. In this study supported by Ministry of Food and Drug Safety in Korea, we identified novel plant-derived substances with significant anti-norovirus activities. The aim of this project was to determine the antiviral activity of a wide range of natural substances, including plant-derived extracts and essential oils, using a norovirus surrogate system, human norovirus replicon-bearing cells, and mouse in vivo experiments. During the activity screening test, we identified novel anti-norovirus substances or oils using plaque assay with MNV-1. Six selected substances were formulated into an optimum mixture and used as an ingredient for salad sauce of which anti-novovirus activity was confirmed(pending for patent and paper submission). The potential application of selected natural substances as a metal surface sanitizer was also tested. Interestingly, the mixture of selected natural compounds showed a significant inhibitory effect against norovirus. These results suggest that these substances may be used as food ingredient with anti-norovirus antivity or components for surface sanitizers to prevent norovirus contamination.

• 산업융합연구
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• 제21권2호
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• pp.79-84
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• 2023

본 연구는 청소년층에서 성인층으로 진입하는 청년층의 성별에 따른 남용약물에 대한 사용실태와 인식을 살펴 보기 위해 분석 가능한 설문지 1051부를 토대로 분석하였다. 설문에 참여한 청년들의 성별을 보면 남자 686명, 여자 365명이었으며, 성별에 따라 남용되는 약물의 종류와 마약류 및 남용약물에 대한 폐해 인식에 대해 분석하였다. 연구결과 술, 담배, 식욕억제제, 진정수면제, 아편계열 진통제 사용 경험이 성별에 따라 통계적으로 유의하였으며, 마약류 및 남용약물에 대한 폐해 인식 중 위험성과 유발문제인식, 위험성에 대한 공감에 대해서도 유의한 결과를 보였다. 마약류 및 약물남용 문제를 개선하기 위한 바람직한 방안은 여성은 257명(68.2%)가 홍보(계몽) 활동을 원하는 것으로 나타났으며, 마약류 및 약물남용 예방을 위한 효과적인 교육에 대해서 남성은 379명(54.2%)이 인터넷 온라인교육으로 나타났다. 남용약물에 의한 청년층의 약물 중독이 증가하고 있는 현실에서 약물사용에 대한 올바른 교육과 홍보가 필요하다고 사료된다.

• Preventive Nutrition and Food Science
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• 제10권1호
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• pp.95-102
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• 2005

The term pharmacognosy as applied to a constituent scientific discipline of Korean Medical Food (KMF) has been in use for nearly several years, and it refers to studies on the pharmacological properties of natural products foods. During the last half of the 20th century, pharmacognosy for KMF evolved from being a descriptive botanical subject to one having a more chemical and biological focus. At the beginning of the 21st century, teaching pharmacognosy for KMF teaching in academic culinary arts and natural healing institutions has been given new relevance as a result of the explosive growth in the use of herbal foods (health foods) in modern KMF practice. In turn, pharmacognosy for KMF research areas are continuing to expand, and now include aspects of cellular and molecular biology in relation to natural products, ethnobotany and phytotherapy, in addition to the more traditional analytical method development and phytochemistry. Examples are provided in this review of promising bioactive compounds obtained in two multidisciplinary natural product KMF development and discovery projects, aimed at the elucidation of new plant-derived cancer chemotherapeutic agents and novel cancer chemopreventives, respectively. The systematic study of KMF offers pharmacognosy groups an attractive new area of research, ranging from investigating the biologically active principles of KMF and their mode of action and potential active substance interactions, to sanitary and quality control, and involvement in clinical trials.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제44회 동계 정기학술대회 초록집
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• pp.627-627
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• 2013

Recently, most studies concerning inorganic CdSe/ZnS quantum dot (QD)-polymer hybrid LEDs have been concentrated on the structure with multiple layers [1,2]. The QD LEDs used almost CdSe materials for color reproduction such as blue, green and red from the light source until current. However, since Cd is one of six substances banned by the Restriction on Hazardous Substances (RoHS) directive and classified into a hazardous substance for utilization and commercialization as well as for use in life, it was reported that the use of CdSe is not suitable to fabricate a photoelectronic device. In this work, we demonstrate a novel, simple and facile technique for the synthesis of ZnO-graphene quasi-core.shell quantum dots utilizing graphene nanodot in order to overcome Cd material including RoHS materials. Also, We investigate the optical and structural properties of the quantum dots using a number of techniques. In result, At the applied bias 10 V, the device produced bluish-white color of the maximum brightness 1118 cd/$m^2$ with CIE coordinates (0.31, 0.26) at the bias 10 V.

• KIEAE Journal
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• 제8권1호
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• pp.81-86
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• 2008

Due to the recent environmental problems, lots of studies on the solutions to reduce the environmental pollutions are on the way. In the field of construction, concrete that we are currently consuming approximately 1 ton each year is the most common and cheap building material. We must cut down on this preoccupied use of this material and develop an alternative material as recommended by the late environmental standards. In this regard, this study propose the 'yellow soil' as the main substance that composes the final state, 'yellow soil concrete'. This study also aims to analyze the physical and chemical performances of this concrete mixed with the yellow soil by comparing it with the cement and assesses the possibility of its application to the cement. The results of the experiment shows that, assuming the solidity of the cement concrete to be around $210kg/cm^2$ (20.58MPa), the solidity of the yellow soil combined material may be around 45%~55% in terms of the range of W/B use, 200 to 400 in the per unit fission amount and less than 2% in the addition proportion of admixing agents. But the scope of the optimal concoction amount of the yellow soil concrete should better be limited as following. 40% to 50% in W/B, 300 to 400 in the per unit fission amount and less than 2% in the addition of admixing agents.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2008년도 추계 학술발표회
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• pp.1673-1677
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• 2008

A method of construction with a basis treatment that uses a latticed bamboo mat puts bamboo's peculiarity and bamboo mat's bending substance to use, and a latticed bamboo mat equally distributes to embankment loading in a basis ground. Therefore it prevents ground destruction by an ill-balanced load and an irregular ground subsidence, and it makes safety system. This investigation make progress a soil box model by a dredged reclamation ground of west and south sea at domestic area, and make a comparative study and analyze the strengthening effect based on a grid size of a bamboo-mat and ground failure that it will use in the field.

• 한국분말재료학회지
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• 제27권6호
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• pp.458-463
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• 2020

Hispidin is a secondary metabolite found in numerous medicinal mushrooms that has attracted significant attention, owing to its distinct biological effects, including antioxidant, anti-inflammatory, antitumor, and cytoprotective properties. Experiments are being carried out to study the interaction of detonation nanodiamonds (DNDs) with synthetic and natural hispidin sourced from extracts of Pholiota sp. fungus. The bioluminescence method is used to determine the adsorption/desorption properties of DNDs toward hispidin. It is found that hispidin forms strong conjugates with DNDs, and the use of various eluents does not result in a significant release of the adsorbed hispidin molecules. DND-bovine serum albumin (BSA) complex, where DNDs serve as a carrier for the protein and the latter acts as a hispidin sorbent, has been developed and applied in hispidin adsorption/desorption tests. The results support the use of the DNDs as a carrier for hispidin in medical applications. They also advocate the application of the DND-BSA complex for isolating the substance from fungal extracts.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.295-303
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• 2022

Residential heating systems in South Korea are largely based on the use of ondol pipelines. Heat is transferred to the floor by passing hot water through a metal or plastic pipe buried within the concrete of the floor. Consequently, it is difficult to clean the inside of these pipes after installation. Over time, foreign substances such as scale accumulate in the pipe when the ondol heating method is used for an extended period. Therefore, in the past, pipes were cleaned by removing foreign substances attached to the inside surfaces of the pipes using high-pressure water or by disassembling the pipes and removing foreign substances with chemical agents. Recently, a method for removing foreign substances through the cavitation effect of ultrasound has been proposed. This idea might lead to the development of new technologies for cleaning pipe interiors. Consequently, this study investigated the use of ultrasound to clean pipes embedded in concrete. In this study, devices that generated ultrasonic waves with various frequencies and directions were prepared. After preparing arbitrarily contaminated pipes, the appropriate frequency, output strength, and output direction for each foreign substance were determined through repeated experiments. The results of this experiment could provide important information for future methods of cleaning the interior of ondol piping systems.

• 한국미생물·생명공학회지
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• 제37권2호
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• pp.125-132
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• 2009

항생제 대체물질로서 양돈용 생균제를 개발하기 위하여, 돼지의 소장 및 대장으로부터 500균주의 미생물을 분리하였으며, 항균물질인 박테리오신을 생산하는 5균주를 최종적으로 선발하였다. 선발균주들은 모두 Lactobacillus 속으로 동정되었으며, 생균제를 개발할 목적으로 상기 균주 중 Lactobacillus sp. HN 235 균주에 대한 균주 및 박테리오신 특성을 조사하였다. HN 235 균주의 성장시간에 따른 생균수 및 항균활성을 측정한 결과, 18시간째 최대 $3.5{\times}10^9\;cfu/mL$까지 성장하였으며, 항균활성은 유도기에 나타나기 시작하여 정체기에 6,400 AU/mL로 최고의 활성을 보이다가 급격하게 활성을 상실하였다. HN 235 균주가 생산하는 박테리오신은 병원성 균주로 알려진 L. monocytogenes와 Cl. perfringens에 대하여 강한 항균능력을 나타냈으며, 상기 박테리오신의 항균활성은 단백질 분해효소 처리시 활성을 상실하였다. 또한 $95^{\circ}C$에서도 활성을 유지하였으며, pH 2~10 범위 및 유기용매에 대해서도 비교적 안정한 항균활성을 나타내었다. SDS-PAGE를 실시하여 분자량을 측정한 결과, 대략 5 kDa으로 확인되었다.

• 한국건축시공학회지
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• 제16권6호
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• pp.571-578
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• 2016

본 연구에서는 갯벌의 콘크리트용 혼화재 및 채움재로써의 활용 가능성에 대한 기초적 연구를 실시하였다. 먼저, 혼화재로서의 활용 가능성에 대해 화학 성분 분석을 실시한 결과 잠재수경성 및 포졸란 반응에 필요한 성분들이 함유되어있었지만 플라이애시 및 고로슬래그의 성분 분석 결과와 비교한 결과 성분 함유량이 소량으로 반응을 하기에는 부족한 양이었다. 또한, 물리적 실험 분석 결과 갯벌 치환율이 증가할수록 압축강도 및 인장강도가 감소하는 것으로 나타났다. 따라서 갯벌의 혼화재로서의 활용 가능성은 화학 성분분석에서 예상한 결과와 마찬가지로 낮은 것으로 나타났다. 채움재로서의 활용 가능성에 대한 시험을 실시한 결과 재령 28일 압축강도를 측정한 결과 갯벌의 채움재로서 활용가능성에 대한 분석을 통해 갯벌 치환율 10~30% 까지 벽돌의 압축강도 기준인 8MPa 이상의 강도를 발현하여 벽돌 등 2차 제품에 활용 가능할 것으로 판단되며, 향후 벽돌제작 등의 추가적인 실험이 필요할 것으로 판단된다. 플로우 시험결과에서는 갯벌 치환율이 증가할수록 플로우 값이 감소하는 것으로 나타났으며, 염화물 함유량 분석 결과를 통해 갯벌 자체의 염분 함유량이 많아 갯벌을 치환할 경우 철근 사용구조물에는 적용하기에는 부적합한 것으로 판단되며, 내장벽돌 등 철근을 사용하지 않는 제품에 활용이 가능할 것으로 판단된다.