• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.1-11
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• 2004

Objectives: The effects of peroxisome proliferator-activated receptor ${\gamma}2\;(PPAR{\gamma}2)$ Pro12Ala (P12A) polymorphism on body mass index (BMI) and type 2 diabetes are well documented; however, until now, only a few studies have evaluated the effects of this polymorphism on body fat distribution. This study was conducted to elucidate the effects of this polymorphism on computed tomography (CT)-measured body fat distribution and other obesity-related parameters in Korean female subjects. Methods & Results: The frequencies of $PPAR{\gamma}2$ genotypes were: PP type, 93.0%; PA type, 6.8%; and AA type, 0.2%. The frequency of the A allele was 0.035. Body weight (P .012), BMI (P .012), and waist-to-hip ratio (WHR) (P .001) were significantly higher in subjects with PA/AA compared with subjects with PP. When body composition was analyzed by bioimpedance analysis, lean body mass and body water content were similar between the 2 groups. However, body fat mass (P .003) and body fat percent (P .025) were significantly higher in subjects with PA/AA compared with subjects with PP. Among overweight subjects with BMI of greater than 25, PA/AA was associated with significantly higher abdominal subcutaneous fat (P .000), abdominal visceral fat (P .031), and subcutaneous upper and lower thigh adipose tissue (P .010 and .013). However, among lean subjects with BMI of less than 25, no significant differences associated with $PPAR{\gamma}2$ genotype were found, suggesting that the fat-accumulating effects of the PA/AA genotype were evident only among overweight subjects, but not among lean subjects. When serum lipid profiles, glucose, and liver function indicators were compared among overweight subjects, no significant difference associated with $PPAR{\gamma}2$ genotype was found. Changes in body weight, BMI, WHR, and body fat mass were measured among overweight subjects who finished a 1-month weight lose program of a hypocaloric diet and exercise; no significant differences associated with $PPAR{\gamma}2$ genotype were found. Conclusions: The results of this study suggest that the $PPAR{\gamma}2$ PA/AA genotype is associated with increased subcutaneous and visceral fat areas in overweight Korean female subjects, but does not significantly affect serum biochemical parameters and outcomes of weight loss programs.

• The Korean Journal of Emergency Medical Services
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• v.13 no.2
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• pp.61-72
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• 2009

Purpose : This study aimed to analyze the posttraumatic stress research trends in Korean and foreign firefighters. Method : Total 63 published international articles were searched by Pub Med internet site and total 17 published Korean articles were searched by Korean Medical Database internet site using 'PTSD in firefighters'. These articles were analyzed by published time, domains of journal, research designs, key words and research subjects. Result : 1) By the published time, there were 29 disaster-related researches(46.0%) and 34 job-related researches(54.0%) among 63 international articles. However, there were 16 disaster-related researches(94.1%) and 1 job-related research (5.9%) of Korean 17 articles. 2) By the international research domain, 9 researches(14.3%) were published in The Journal of Nervous and Mental Disease. Among domestic research domain, there were 9 researches(52.9%) consisting of 6 master's degrees and 3 doctor degrees. In major analysis of Korean domain, the highest portion is 4 psychology researches. (23.5%) 3) In the term of the international research design, quantitative research methods were highly used in both 23 disaster-related researches (36.5%) and 30 job-related researches(47.5%). In domestic research, quantitative research methods were mostly used in 14 job-related researches(82.3%) and Q methodology was only used in 1 disaster-related research(5.9%). 4) Looking on the research content trends according to the key words, 9 researches (31.0%) done on posttraumatic stress and coping had the most research and was followed up by posttraumatic stress symptom. Among these researches, key words for PTSD(Posttraumatic Stress Disorder) and PTS(Posttraumatic Stress) were mostly used. Moreover, there was 1 domestic study done on verifying the trends of Posttraumatic Stress in disaster-related research with PTS as the key word. In job-related research, the relationship between the Posttraumatic Stress and other factors had the most with ten studies (62.5%). Among these researches, key words for 5 PTSD(31.3%) were mostly used. 5) According to the international research subjects, the Posttrau consist the most subjects with 16 cases each for disaster and job related stress ; however, domestic research had 16 studies(94.1%) only using firefighters and 1 (5.9%) with their families as subjects. Conclusion : Although the studies of Posttraumatic Stress on Korean firefighters had started later than those on Foreign firefighters, first used for crucial topics show research development in various fields of study and should be tested for studies like those done in abroad regarding multiple topics and methods.

• Journal of Nutrition and Health
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• v.39 no.8
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• pp.832-840
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• 2006

This study was performed to investigate the relationship between diet quality and food cost and identify the effects of food cost on healthy diet among Korean adult. Among the subjects of 2001 National Health and Nutrition Survey 1,641 men and 1,765 women aged from 30 to 49 years were selected and their information of dietary intakes, socio-demo-graphic information, and anthropometric data were analyzed. For the analysis, subjects were classified to quartile based on their daily food cost. Food guidelines provided by Korean Nutrition Society was regarded as a model of healthy diet. Subjects in the lowest quartile of food cost consumed inadequate amount of food from all food categories of the guidelines. Many subjects in the highest quartile not only satisfied the recommended amount of the Food Guide but also seemed to overeat high energy density foods. Even in the highest quartile, about 90% of subjects did not satisfied recommended amount of dairy products. According to the calculated cost of healthy diet, the average cost did not seem to be more expensive than the current mean food cost of the subjects, and most cost-sensitive food intake was observed in the meat fish beans eggs category. The implications of study results were: 1) all the high cost diets did not indicate the high quality of diet, 2) most practical matter of healthy diet in low income group seemed whether they could afford the expense of meat and fish, 3) nutrition education was required to most subjects for healthy diet.

• Women's Health Nursing
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• v.24 no.1
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• pp.90-103
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• 2018

Purpose: To analyze articles published in the Korean Journal of Women Health Nursing from 2013 to 2017 to determine the latest research trends and understand how 2013 Korea Women's Health Statistics were reflected in journal articles. Methods: A total of 130 studies were analyzed. Research design, types of research, research framework, research subjects, characteristics of quantitative research, characteristics of qualitative research, and keywords were analyzed using a structured analysis format. Results: Quantitative and qualitative research accounted for 83.8% and 13% of these 130 studies analyzed, respectively. Non-experimental and experimental research accounted for 70.7% and 13.1% of these studies, respectively. The most frequent study subjects were childbearing women (62.8%), including college students, mothers, and adults. A total of 69.1% of non-experimental research and 88.2% of experimental research used convenience sampling. Questionnaires were most frequently used for data collection. The most frequent keyword domain involved health-related concepts (41%) among nine domains and the most frequently used keyword was "women." Conclusion: This study suggest that further experimental research should be conducted in the future. Also, adolescent and the elderly women should be focused on as subjects in future studies based on results of 2013 Korean Women's Health Statistics.

• Journal of Korean Academy of Nursing
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• v.19 no.2
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• pp.160-172
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• 1989

This research was done to clarify the factors related to sexual satifaction in women who have had a hysterectomy, and to idenify which factors had statistically significant influence of sexual satisfaction of the subjacts. The objective of this study was to identify the variables related to sexual adaptation which might be changed by nursing intervention. This was a cross-sectional descriptive correlation study. There were 230 subjects in the study, and they were selected by a convenient sampling method. The tool. for this study was developed by the researcher through modification of the Dergatis Sexual Function Inventory(DSFI). A pilot study was done to determine the necessary modifications. Data collection was done between Sept. 1987 and Du. 1987 using a mailed questionnaire. The characteristics of the subjects were as follows : The mean age of the subjects was 42.3 years and 204(87.4%) of the subjects had nine or more years of education. The mean income of the subjects was 85.8870 won / month, and 179(77%) of them were housewives. The mean number of pregnancies and children were 4.9 and 2.5 respectively. Oophorectomies were included in the surgery for 66(28.7%) of the subjects. Only 12(5.2%) were planning to have more children. Only 88(38.3%) of the subjects had received information prior to the surgery regarding health problems related to the operation and less than half, 111 (48.3%), had received this kind of information before discharge. Lay persons were the source of information about the post-operation status for 196 (85.2%) of the subjects, but the content of the information did not significantly influence the sexual satisfaction score. Only 16(7.0%) of the subjects said they regretted having a hysterctomy while 102(44.3%) said they were pleased to have had a hysterectomy. Ninety (39.1 %) of the subjects reported that their husbands had “stress” and 164(71.3%) of the subjects reported “stress”. The results of this study are summarized as follows : 1. The mean score for sexual satisfaction of the subjects was 34.24 with a possible maximum score of 50.00. Eighty two(35.8%) were responded that they were satisfied with their sexual life but 61 (26.5%) were responded that they were dissatisfied with their sexual life 2. The following 15 factors extracted from the results of the data analysis were significantly related to sexual satisfaction(p＜.05) ; support of husband, body image, emotion, knowledge of sex, menopausal symptoms, sexual behavior, the feelings the subjects had about the hysterectomy, stress for both subject and husband, the number of children, health information given before operation, job, age, level of education and income. The five most important factors influencing sexual satisfaction were identified by using stepwise multiple regression analysis. The most important factor was support of husband, which explained 17.83% of the total variance. The remaining factors in order of significance were : Knowledge of sex, income, job, and emotional status. Those five factors explained 35.16% of the sexual satisfaction. In conclusion, for the care of women who are going to be discharged from hospital after having had a hysterctomy, nurses have to work with the husbands to help them to understand the importance of their support. Nurses also need to make sure that the subjects have an adequeate knowledge of sexual life after a hysterectomy. Also nursing interventions should focus on subjects who do not have a job, who are of low economic status, and the subjects who are under the unpleasant mood.

• Journal of the Korean School Mathematics Society
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• v.16 no.1
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• pp.265-287
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• 2013

The purpose of this study was to analyze the trends of domestic research on teacher knowledge in mathematics in terms of its conceptualizations of teacher knowledge, topics, methods, subjects, and content domains. For this purpose, the papers published in 9 professional journals during the recent 14 years (1999-2012) were analyzed by 5 criteria. The results of this study showed that the concept of PCK was the most frequent, whereas its subcategories appeared in different forms. The most frequent research topic was survey of teacher knowledge. The qualitative research methodology was more frequently used than the quantitative methodology, whereas mixed one was hardly used. The subjects for research included a little more elementary school teachers than secondary counterparts, but did similarly both pre-service and in-service teachers. Whereas both the research on number and operations in elementary mathematics education and the research on function in secondary were active, the rest of content domains were not. On the basis of these results, this paper provides several implications for future research direction in teacher knowledge in mathematics.

• Journal of Korean Academy of Nursing Administration
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• v.7 no.3
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• pp.561-569
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• 2001

This study was designed to analyze all the papers that were in the Journal of the Korean Nursing Administration Academic Society from the first publication edition (1995) to 2000. Analyses methods are research designs, data collection methods, research subjects and key words. all papers were 145. The results of the study are as follows : First, research designs, nonexperimentals are 106 papers, experimentals are 9, qualitatives are 9 papers. Research subjects that all subjects in each paper were accepted are as follows, hospital staffs including nurses, doctors, and other employees are 115 paper(59.28%), adults including patient's family, medical, nursing students are 44 papers(22.68%), informatic systems including medical record sheets, database, and management system are 8 papers(4.12%), others including country, literature, researches are 21 papers(10.82%). Second, data collection methods that all methods in each paper were accepted that questionnaires are 93 papers(57.76%), interviews are 13 papers(8.07%), observations are 10 papers(6.21%), scale & psycholgical are 8 papers(4.97%), and self-reportings are 6 papers(3.73%), etc. Conclusion : Even though research topics are various, the fields of informatics and financial management are poor. Therefore studying for those fields and its practical implication are needed.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.2
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• pp.77-89
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• 2019

Objectives : In this study, We overviewed study trend on 'Mibyung' by analyzing articles published in Korea from 1997 to 2019. Methods : We collected research articles on 'Mibyung' from 7 Korean research databases using the keyword '미병' and '아건강'. Then we analyzed them by publish year, journal, and research subjects. Research subjects were categorized into 'diagnosis', 'relationship with other factors', 'trend', 'concept', 'application development', 'policy research', 'prevalence and recognition', 'clinical report' or 'animal study'. Results & Conclusions : The largest number of related articles was published in 2017(12 articles, 26.7%). 'Journal of Society of Preventive Korean Medicine' was the journal with the most published articles(16 articles, 35.6%). Most of the research subjects were about diagnosis(11 articles, 24.4%) and analysis on relationship with other factors(10 articles, 22.2%). Little were published on policy(4 articles, 8.9%) and clinical study(1 article, 2.2%). More research on policy and clinical trials should be implemented for future mibyung study.

• The Korean Society of Law and Medicine
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• v.20 no.2
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• pp.173-206
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• 2019

This research examines the characteristic of regulation on Japanese clinical research in recent years. First, Japan has had a severe punishment policy on research misconduct like Korea, but, in recent days, Japan has changed the direction of research ethics policy from restriction to research publicness securement by educational training, in addition, Act of Clinical Research, effected April 2018, has recruited excellent researchers, and then integrated clinical research and medicine clinical trial through raising transparency of funding and integrating ethics screening by mandating announcement on funding information of clinical research. Second, Japan has integrated and organized ethics guideline from dual system that consists of ethics guideline on dynamic research(here after, referred to as 「dynamic guideline」) and ethics guideline on clinical research(here after, referred to as 「clinical guideline」) to ethics guideline on medical research aimed at human(here after, referred to as 「integrated guideline」), thus, it complements repetition and deficit of ethics guideline needed in clinical research and dynamic research, and it has risk evaluation system for protecting human subjects, and also it clarifies the concept of 「invasiveness」, a preliminary consideration of evaluation. 「Evaluation issue of risk and profit」, common contents of international regulation related clinical research, is the method to check whether the research is designed appropriately or not, this is the method for Institutional Review Board to decide whether the risk on human subjects could be justified, and also this is the important standard for future human subjects to participate in clinical trial. Therefore, it is meaningful to define 「invasiveness」 concept, a preliminary consideration of risk evaluation for human subjects. This research examines Japanese clinical trial focusing on change of awareness on prevention of research misconduct, efficiency improvement of research through research screening and integration of human subjects, and clarification and extension of range of 「invasiveness」 concept, a preliminary of risk evaluation to protect human subjects.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.30 no.1
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• pp.67-74
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• 2020

Objectives: Previous study has shown that the positive rate of latent tuberculosis infection(LTBI) among former workers in dusty environments was higher than that among high-risk groups of tuberculosis(TB). The objective of the present study was to identify the development of active TB among former workers in dusty environments diagnosed with LTBI. Methods: Between January 2015 and May 2017, 796 former workers in dusty environments who had been subjects of epidemiology research for work-related chronic obstructive pulmonary disease(COPD) had received the QuantiFERON-TB® Gold In-Tube(QFT-GIT) from the Institute of Occupation and Environment(IOE) under the Korea Workers' Compensation and Welfare Service(KCOMWEL). Among them, 437 participants who received a health examination for work-related pneumoconiosis between January 2015 and December 2018 were selected as study subjects. Active TB was defined as a positive result for active PTB and non-tuberculosis mycobacteria infection in the result of the Pneumoconiosis Examination Council's assessment by KCOMWEL. Results: A total of 437 subjects were followed up for 2.1 years. Four of them(4/437, 0.9%) developed active TB during the follow-up period. The attack rate of active TB among subjects who were diagnosed LTBI positive and those who were diagnosed LTBI negative were 0.9%(3/320) and 0.9%(1/115), respectively. Conclusions: Most previous studies reported that the attack rate of the development of active TB in subjects who had been diagnosed LTBI positive was higher than that among subjects who had been diagnosed LTBI negative. To the contrary, the present study found that the rate of developing active TB among former workers in dusty environments diagnosed as LTBI positive was not higher than that in those who were diagnosed LTBI negative.