• Asian Pacific Journal of Cancer Prevention
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• v.13 no.10
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• pp.4943-4946
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• 2012

Studies have reported an association between the TERT rs2736098 single nucleotide polymorphism (SNP) and cancer susceptibility, but the results remain inconclusive. Toprovide a more precise estimation of the relationship, a meta-analysis of 8 published studies including 8,070 cases and 10,239 controls was performed. Stratification by sample size, genotyping method, source of controls and ethnicity were used to explore the source of heterogeneity. In the overall analysis, no significant association was found between the TERT rs2736098 polymorphism and cancer risk. However, the result showed the rs2736098 was significantly associated with an increased cancer risk and the heterogeneity was effectively decreased for homozygote comparison by removal of two studies: OR = 1.337 (95% CI = 1.183-1.511; Pheterogeneity = 0.087). In the subgroup analysis by ethnicity, a significantly increased risk of cancers was found among Asians (OR = 1.413, 95% CI = 1.187-1.683 for AA versus GG). Our meta-analysis did not show that the TERT rs2736098 plays an important role in cancer risk. More studies with larger sample size and well-matched controls are needed to confirm the findings.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.4
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• pp.149-160
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• 2018

An alternative method for team diversity studies is to examine demographic faultlines. A concept of demographic faultline enables us to better understand team dynamics with multidimensional diversity. This study suggests the demographic faultline as a new situational factorto influence the relationship between leader teamwork behaviors and a climate of support for innovation. When subgroups divided by demographic faultline are homogeneous within them and heterogeneous between them, the homogeneity may increase intimacy in each subgroup while the heterogeneity may increase exclusiveness between those subgroups. We argued that a leader could play an important role to build a cooperative relationship between faultline-based subgroups and highlight positive aspects of developing and maintaining subgroups in organizations. With a sample of 81 teams (558 employees), it was examined how leader teamwork behaviors would affect a team-level climate of support for innovation and how this relationship would be moderated by each team's demographic faultline (gender, age, and educational specialty). As predicted, it was found that there was a significant positive relationship between each leader's teamwork behaviors and each team's climate of support for innovation. In addition, this relationship was stronger for teams with strong faultline than with weak faultline. Our findings and their implications were further discussed.

• Physical Therapy Korea
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• v.16 no.3
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• pp.50-59
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• 2009

The aim of the study was to evaluate the effectiveness of exercise therapy on physical function of patients with anklyosing spondylitis (AS) through the systemic review and meta-analysis. The 54 studies were identified from computerized search of published researches on PubMed, Embase, CINAHL, PEDro, KISS, KERIS database until February, 2008 and review of reference lists. The main search terms were the combination "ankylosing spondylitis", "exercise", "spondyloarthropathy and exercise", "ankylosing spondylitis and physical therapy". The subgroup analysis was performed by the publication year, quality score, type of disease, content of intervention, intervention provider, type of intervention, method of intervention, intervention period and the point of outcome measured. Two reviewers independently selected trials for inclusion, assessed the quality and extracted the data. The result was as follows: The 10 trials were eligible for inclusion criteria, then the systematic review and meta-analysis was assessed on effectiveness of exercise therapy. The meta-analysis of 10 studies based on the random effect model showed that the exercise therapy was beneficial in treating the diseases (effect size .55; 95% confidence interval -.3.75~.61). The findings suggest that the exercise therapy would be appropriate to manage the physical function of AS with evidence based on Meta-analysis. Therefore, the exercise therapy supervised by physical therapist should be recognized as the essential approach to manage the AS and necessarily recommended to improve physical function.

• Journal of KIISE:Information Networking
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• v.29 no.4
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• pp.346-351
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• 2002

We improve a new probabilistic public key cryptosystem, in which the one wav function was defined only on the discrete logarithmic functions, proposed by Okamoto and Uchiyama. The plaintexts are calculated from the modular product of two these functions, one of which has a fixed value depending on a given public key. The improvement is achieved by a well-chosen public key assuming an unit element 1 as the fixed function value. Because it is possible to reduce the number of operations at the decryption. Also the concrete method for a public key of our improved scheme is suggested.

• Journal of Korea Society of Digital Industry and Information Management
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• v.17 no.4
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• pp.109-120
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• 2021

Despite the growing online exposure of retailes, offline retail channels still outperform online channels in the total retail volume of some countries. There is much interest in the physical layout plans of retail stores to expand sales. Product placement that have a large impact on customer purchasing behavior at offline retailers influences customer movement and sales volume. But in many cases, each retailer relies on unsystematic and autonomous product placement. When multiple products are sold with one purchase, the customer's movement for shopping may be evaluated in terms of customer efficiency and additional impulse purchase. In this paper, the social network is applied to sales data of a retail store and the result is used for evaluation of product placement and customer path. The frequent sales product composition was identified using k-core from sales data in the form of shopping baskets. The location was checked for the identified compositions of products, the spatial variance was measured and the customer's path was identified. With these results, the store arrangement of products was evaluated with appropriate improvement directions. The analysis method of this paper can be an alternative analysis approach for better layout of retail stores.

• The Journal of Advanced Prosthodontics
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• v.16 no.1
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• pp.25-37
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• 2024

PURPOSE. To investigate the effect of sintering programs and surface treatments on surface properties, phase transformation and flexural strength of monolithic zirconia. MATERIALS AND METHODS. Zirconia specimens were sintered using three distinct sintering programs [classic (C), speed (S), and superspeed (SS)] (n = 56, each). One sample from each group underwent scanning electron microscopy (SEM) and grain size analysis following sintering. Remaining samples were divided into five subgroups (n = 11) based on the surface treatments: control (CL), polish (P), glaze (G), grind + polish (GP), and grind + glaze (GG). One sample from each subgroup underwent SEM analysis. Remaining samples were thermally aged. Monoclinic phase volume, surface roughness, and three-point flexural strength were measured. Monoclinic phase volume and surface roughness were analyzed by Kruskal-Wallis and Dunn tests. Flexural strength was analyzed by two-way ANOVA and Weibull analysis. The relationships among the groups were analyzed using Spearman's correlation analysis. RESULTS. Sintering program, surface treatment, and sintering × surface treatment (P ≤ .010) affected the monoclinic phase volume, whereas the type of surface treatment and sintering × surface treatment affected the surface roughness (P < .001). Type of sintering program or surface treatment did not affect the flexural strength. Weibull analysis revealed no significant differences between the m and σ_o values. Monoclinic phase volume was positively correlated with surface roughness in the SGG and SSP groups. CONCLUSION. After sintering monolithic zirconia in each of the three sintering programs, each of the surface treatments can be used. However, for surface quality and aging resistance, G or GG can be recommended as a surface finishing method.

• Nuclear Engineering and Technology
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• v.56 no.6
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• pp.2208-2219
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• 2024

Kylin-2 is an advanced neutronics lattice code, developed by Nuclear Power Institute of China. High-precision multigroup cross section library is need for KYLIN-2 to carry out simulation of current pressurized water reactor (PWR) and advanced reactor. In this paper a multigroup cross section library generation system named TPAMS was developed, the methods in TPAMS dealing with resonance data such as subgroup parameters, lambda factor, resonance integral were discussed. Moreover, the depletion chain simplification method was studied. TPAMS can produce multigroup library in binary and ASIIC formats, including detailed data contents for resonance, transport and depletion calculations. A multigroup cross section library has been generated for KYLIN-2 based on TPAMS system. The multigroup cross section library was verified through the analysis of various criticality and burnup benchmarks, the values of multiplication factor and isotope density were compared with the experiment data. Numerical results demonstrate the accuracy of the multigroup cross section library and the reliability of the multigroup cross section library generation system TPAMS.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.9
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• pp.4247-4250
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• 2016

Background: Pax8 and peroxisome proliferator-activated receptor gamma 1 gene (Pax8-$PPAR{\gamma}1$) are important factors in tumors. Several studies have suggested that follicular thyroid cancer may arise from Pax8- $PPAR{\gamma}1$ rearrangement. In order to have a better understanding of the association between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer, we conducted the presenmt meta-analysis. Materials and Methods: The information was extracted from PubMed, EMBASE and Web of Science. Statistic analysis was performed with Stata12.0 software. Odds ratios (ORs) were calculated using a fixed-effects model. We also performed heterogeneity and publication bias analyses. Results: Nine studies including 198 follicular thyroid cancer patients and 268 controls were considered eligible. The frequency of Pax8-$PPAR{\gamma}1$ rearrangement was significantly higher in the follicular thyroid cancer group than in the control group, with a pooled OR of 6.63 (95%CI=3.50-12.7). In addition, through subgroup analysis, the OR between Pax8-$PPAR{\gamma}1$ rearrangement and follicular thyroid cancer was 6.04 (95%CI = 3.18-11.5) when using benign tumor tissues as controls. The OR for the method subgroup was 9.99 (95% CI =4.86-20.5) in the RT-PCR. Conclusions: The final results demonstrated that Pax8-$PPAR{\gamma}1$ rearrangement has significant association with follicular thyroid cancer.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.1
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• pp.151-157
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• 2019

This study is about the process capability index (PCI). In this study, we introduce several indices including the index $C_{PR}$ and present the characteristics of the $C_{PR}$ as well as its validity. The difference between the other indices and the $C_{PR}$ is the way we use to estimate the standard deviation. Calculating the index, most indices use sample standard deviation while the index $C_{PR}$ uses range R. The sample standard deviation is generally a better estimator than the range R. But in the case of the panel process, the $C_{PR}$ has more consistency than the other indices at the point of non-conforming ratio which is an important term in quality control. The reason why the $C_{PR}$ using the range has better consistency is explained by introducing the concept of 'flatness ratio'. At least one million cells are present in one panel, so we can't inspect all of them. In estimating the PCI, it is necessary to consider the inspection cost together with the consistency. Even though we want smaller sample size at the point of inspection cost, the small sample size makes the PCI unreliable. There is 'trade off' between the inspection cost and the accuracy of the PCI. Therefore, we should obtain as large a sample size as possible under the allowed inspection cost. In order for $C_{PR}$ to be used throughout the industry, it is necessary to analyze the characteristics of the $C_{PR}$. Because the $C_{PR}$ is a kind of index including subgroup concept, the analysis should be done at the point of sample size of the subgroup. We present numerical analysis results of $C_{PR}$ by the data from the random number generating method. In this study, we also show the difference between the $C_{PR}$ using the range and the $C_P$ which is a representative index using the sample standard deviation. Regression analysis was used for the numerical analysis of the sample data. In addition, residual analysis and equal variance analysis was also conducted.

• Journal of Korean Neurosurgical Society
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• v.64 no.2
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• pp.297-308
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• 2021

Objective : Shunt infection is a common complication while treating hydrocephalus. The antibiotic-impregnated shunt catheter (AISC) was designed to reduce shunt infection rate. A meta-analysis was conducted to study the effectiveness of AISCs in reduction of shunt infection in terms of age, follow-up time and high-risk patient population. Methods : This study reviewed literature from three databases including PubMed, EMBASE, and Cochrane Library (from 2000 to March 2019). Clinical studies from controlled trials for shunt operation were included in this analysis. A subgroup analysis was performed based on the patient's age, follow-up time and high-risk population. The fixed effect in RevMan 5.3 software (Cochrane Collaboration) was used for this meta-analysis. Results : This study included 19 controlled clinical trials including 10105 operations. The analysis demonstrated that AISC could reduce the infection rate in shunt surgery compared to standard shunt catheter (non-AISC) from 8.13% to 4.09% (odds ratio [OR], 0.48; 95% confidence interval [CI], 0.40-0.58; p=0.01; I2=46%). Subgroup analysis of different age groups showed that AISC had significant antimicrobial effects in all three groups (adult, infant, and adolescent). Follow-up time analysis showed that AISC was effective in preventing early shunt infections (within 6 months after implant). AISC is more effective in high-risk population (OR, 0.24;95% CI, 0.14-0.40; p=0.60; I2=0%) than in general patient population. Conclusion : The results of meta-analysis indicated that AISC is an effective method for reducing shunt infection. We recommend that AISC should be considered for use in infants and high-risk groups. For adult patients, the choice for AISC could be determined based on the treatment cost.