• Animal Bioscience
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• v.35 no.10
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• pp.1616-1627
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• 2022

Objective: This work was conducted to investigate the effects of oxidative stress on meat quality, mitochondrial function, calcium metabolism and ferroptosis of broilers. Methods: In this study, a total of 144 one-day-old male Ross 308 chicks were divided into 3 groups (control group, saline group, and hydrogen peroxide [H₂O₂] group) with 6 replicates of 8 broilers each. The study lasted for 42 d. The broilers in the saline and H₂O₂ groups were intraperitoneally injected with 0.75% saline and 10.0% H₂O₂ on the 16th and 37th day of the experimental period respectively, the injection volumes were 1.0 mL/kg of broiler body weight. On the 42nd day of the experimental period, two chicks were randomly selected from each cage, a total of thirty-six chicks were stunned by electric shock and slaughtered to collect breast muscle samples. Results: The H₂O₂ exposure reduced pH value, increased drip loss and shear force of breast meat (p<0.05), impaired the ultrastructure and function of mitochondria. The H₂O₂ exposure damaged the antioxidant system in mitochondria, excessive reactive oxygen species carbonylation modified calcium channels on mitochondria, which impaired the activities of key enzymes on calcium channel, resulted in the increased calcium concentration in cytoplasm and mitochondria (p<0.05). In addition, the H₂O₂ exposure increased the iron content and lipid peroxidation (p<0.05), which induced ferroptosis. Conclusion: Oxidative stress could impair meat quality by causing mitochondrial dysfunction, resulting in calcium metabolism disorder and ferroptosis.

• Journal of Environmental Health Sciences
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• v.45 no.6
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• pp.613-621
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• 2019

Objectives: This study was performed to examine the relationship between health behaviors, living environment, and asthma in adolescents in Korea. Methods: Information on adolescents' characteristics, including demographic factors, health behaviors, and doctor's diagnosis of asthma was obtained from the Korean Youth Risk Behavior Web-based Survey (2015). In total, 68,043 middle and high school students participated. Environmental characteristics, including city park area and outdoor PM₁₀ concentrations in 2015 were obtained from the Korean Statistical Information Service. The adolescents' and environmental characteristics were merged by local information. Multiple logistic regression models were used to investigate the risk factors affecting asthma in adolescents. Results: The prevalence of asthma in adolescents in 2015 was 8.8%. In the multiple logistic regression analysis, adolescents who were male, attended middle school, suffered obesity, experienced tobacco smoking, had physical activity levels of 2 to 4 days, had higher stress levels, and lived in areas with outdoor PM₁₀ concentrations more than 47 ㎍/㎥ were more likely to have asthma, while adolescents who had middle levels of family economic status were less likely to do so. Conclusions: The fact that PM₁₀ concentration can affect asthma is an important point in this study. Risk factors identified in this study could be used as basic data for the prevention and management of asthma in Korea.

• Journal of the Korean Society of School Health
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• v.32 no.3
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• pp.165-174
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• 2019

Purpose: The purpose of this study was to identify the influence of eHealth literacy on health promoting behaviors, thereby providing basic data for the development of interventions for health promoting behaviors among university students. Methods: Data were collected from 242 university students aged 19 and over in a university located in K province in South Korea. Participants responded to structured questionnaires in September 2018. eHealth literacy and health promoting behaviors were measured by eHealth Litaracy (EHL) and a translated version of the Health Promoting Lifestyle Profile (HPLP-II), respectively. The correlation between eHealth literacy and health promoting behaviors were analyzed using Pearson's correlation, and multiple regression analysis was carried out to examine the influence of eHealth literacy on health promoting behaviors. Results: The participants had a moderate level of eHealth literacy with the greatest score recorded in the sub-domain of functional eHealth literacy and the lowest in the sub-domain of critical eHealth literacy. Female students and students who majored in healthcare had higher levels of eHealth literacy than male students and those with non-healthcare majors. The degree of health promoting behaviors was moderate or lower with the highest score being in the sub-domain of interpersonal support and the lowest in the sub-domain of health responsibility. Health promoting behaviors had significant relationships with eHealth literacy, exercise hours, subjective health status, and health concerns. Multiple regression analyses revealed that the participants engaged more in health promoting behaviors when they had greater eHealth literacy (β=.18, p<.001), interest in their own health (β=.33, p<.001), exercise hours (β=.18~.23, p<.001), and subjective health status (β=.17~.18, p=.007~.031). Conclusion: In order to facilitate health promoting behaviors of university students, interventions for health promoting behaviors need to be developed including strategies to improve competencies relevant to critical eHealth literacy and to increase exercise hours.

• Journal of Korean Academy of Rural Health Nursing
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• v.2 no.2
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• pp.145-152
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• 2007

Purpose: The purpose of this study was to suggest new directions for public health programs in rural and remote areas. Method: For this purpose, a literature review was done including articles, research reports, and master theses and doctoral dissertations. Results: Public health programs in rural remote areas were found to be very insufficient in terms of professional personnel and program diversity. Especially, there is a lack of adequate manpower and infra-structure in the public health sub-centers at the township and sub county level. Although community health practitioners at the village level are providing public health service beyond medical care, their coverage rate is very low. Conclusion: The results suggest a need to strengthen the function of public health sub-centers to provide comprehensive public health service based on the life-cycle approach. For this new change, legal and political support must be developed.

• Natural Product Sciences
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• v.29 no.2
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• pp.83-90
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• 2023

To our knowledge, this is the first study aiming to optimize the extraction conditions of total phenolic compounds (TPC) and total flavonoids contents (TFC) from Argania spinosa leaves using Response Surface Methodology (RSM) with a Box-Behnken design (BBD). The optimal conditions obtained were 5% (w/v) solvent-to-solid ratio, 72.33% ethanol concentration, and 10h ours as an extraction time, which resulted in an extract with maximum TPC (131.63 mg GAE/g dw) and TFC (10.66 mg QE/g dw). Under the optimal extraction conditions, the antioxidant activity of the extracts of leaves of argan tree showed a moderate antiradical capacity of DPPH (IC₅₀ = 0,130 mg/mL) and ABTS (IC₅₀ = 0.198 mg/mL). However, the leaves of argan tree showed a very interesting reducing power of Iron (IC₅₀ = 0.448 mg/ml) which is similar to that of the ascorbic acid (IC₅₀ = 0.371 mg/mL).

• Advances in environmental research
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• v.11 no.1
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• pp.17-30
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• 2022

Road transport allows all forms of land conditions to be met at less cost. Because of this function, despite numerous disadvantages, it becomes the most frequently used method of transport, especially in underdeveloped or developing countries. One of the most significant factors used in evaluating the atmosphere's air quality is the amount of CO₂, increasing people's density in indoor spaces. The amount of CO₂ indoors is, therefore, vital to determine. In this study, CO₂ and temperature measurements made on nine different bus journey was made in Turkey. The minimum and maximum values were recorded as 555 ppm and 3000 ppm CO₂, respectively, in the measurements. On all journeys, the average concentration is 1088.72 ppm. The minimum and maximum values were measured as 17.4℃ and 32.7℃ in the temperature measurements, and the average of all trips was calculated to be 25.76℃. In this study conducted before the Covid-19 pandemic, it was determined that the amount of CO₂ increased with the density and insufficient ventilation in the buses. The risk of infection increases in places with high human density and low clean air. For situations such as pandemics, CO₂ measurement is a rapid indicator of determining human density.

• Journal of Environmental Health Sciences
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• v.45 no.3
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• pp.247-257
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• 2019

Objectives: The Korea Ministry of Environment regulates concentrations of hazardous air pollutants (HAPs) through Atmosphere Environmental Standards to protect public health from HAPs. However, simply determining the exceedance of HAP concentrations has several limitations and more comprehensive assessment is required. In addition, integrated risk assessment is needed considering exposure in all microenvironments, including outdoor as well as indoor environments. The purpose of this study was to assess the differences in risk by sub-population groups according to time-activity patterns and reported concentrations, as well as the lifetime risk for Koreans. Methods: In this study, we calculated time-weighted average exposure concentrations for benzene and $PM_{10}$ among preschool-age children, students, housewifes, workers, and the elderly using residential time and concentrations for indoor (house, school or workplace, other), outdoor, and transport by the meta-analysis method. The risk assessments were conducted by excess cancer risk and disease death risk using 1,000,000 Monte-Carlo simulations for probabilistic analysis. Results: Preschool-age children, students, housewifes, workers, and the elderly spent 91.9, 86.0, 79.8, 82.2, and 77.3% of their day in their house, workplace, or school, respectively. The more than 99% excess cancer risk for benzene exceed 1.0E-06 in all sub-populations and lifetime. The acute disease death risk for $PM_{10}$ for housewifes and workers for lifetime were 3.35E-04 and 3.18E-04, and chronic disease death risks were 2.84E-03 and 2.70E-03, respectively. Conclusions: The risk of benzene and $PM_{10}$ by sub-population group and for the lifetime of housewifes and workers were assessed. Benzene showed risky results for this study. All disease death risks of $PM_{10}$ were higher than 1.0E-04 and showed different risks by sub-population. This study can be used as a basis for lifetime exposure and risk assessment to benzene and $PM_{10}$.

• CELLMED
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• v.6 no.2
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• pp.11.1-11.7
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• 2016

The aimed of the presence study was to determine the antiulcer potential of virgin coconut oil (VCO), either extracted by wet process (VCO_A) or fermentation process (VCO_B), and to compare their effectiveness against the copra oil (CO) using the HCl/ethanol-induced gastric ulcer model. Earlier, the oils underwent chemical analysis to determine the free fatty acids composition, physicochemical properties and anti-oxidant capability. In the antiulcer study, rats (n=6) were pre-treated orally for 7 consecutive days with distilled water (vehicle), 100 mg/kg ranitidine (positive group) or the respective oils (10, 50, and 100% concentration). One hour after the last test solutions administration on Day 7^th, the animals were subjected to the gastric ulcer assay. Macroscopic and microscopic analyses were performed on the collected rat's stomachs. From the results obtained, the chemical analysis revealed i) the presence of high content of lauric acid followed by myristic acid and palmitic acid in all oils and; ii) the significant (^*p< 0.05) different in anisidine- and peroxide-value, percentage of free fatty acid, total phenolic content and total antioxidant activity among the oils. The animal study demonstrated that all oil possess significant (^*p< 0.05) antiulcer activity with VCO_B being the most effective oil followed by VCO_A and CO. The macroscopic observations were supported by the microscopic findings. Interestingly, all oils were more effective than 100 mg/kg ranitidine (reference drug). In conclusion, coconut oils exert remarkable antiulcer activity depending on their methods of extraction, possibly via the modulation of its antioxidant and anti-inflammatory activity.

• Particle and aerosol research
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• v.17 no.4
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• pp.115-123
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• 2021

The emission gas from meat grilled restaurants has unpleasant odor and sticky particulate matters (PM) in form of oil mist. This affects the residents living nearby. In oder to decrease the odor and PM, electrostatic precipitators (ESP) were installed at several restaurants by support of Seoul metropolitan government and emission characteristics of PM and odor were investigated. The removal efficiency of odor and PM at before- and after-ESP was that total hydrocarbon (THC), NH₃, H₂S, acetaldehyde, butyraldehyde were not much decreased. Total suspended particles (TSP) emitted from the vent was below the value of 7 mg/m³ regardless of the concentration of before-ESP and removal efficiency was in the range of 64 ~ 86%. The ratio of PM_1.0 to PM₁₀ of emission gas was over 0.9. So it was revealed that most PM of emission gas was PM1.0. The PM concentration in the air of the street near the vent was higher than another street due to the emission gas and the PM of indoor air of restaurant grilling meats was measured very high compared to outdoor air. So it needs more powerful ventilation of indoor air.

• Journal of the Korean Society of Safety
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• v.29 no.5
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• pp.136-145
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• 2014

This article has compared the level of activities of occupational safety and health in workplace among sub-sectors of manufacturing industry in order to set the priority for policy intervention. Data of manufacturing industry in the survey on the current status of occupational safety and health was used with factor analysis and radar graphic method. Authors have categorized sub-sectors of manufacturing industry into four categories, attained group, active group, neglected group, and passive group based on injury rate, level of safety and health activities. The neglected group may be the first target group for occupational safety and health policy guiding some detailed occupational safety and health activities. Limitation of this study is that cross sectional data was analyzed. The long term effect could not be analyzed.