• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3738-3742
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• 2013

The reaction mechanism of $SiF_2$ radical with HNCO has been investigated by the B3LYP method of density functional theory(DFT), while the geometries and harmonic vibration frequencies of reactants, intermediates, transition states and products have been calculated at the B3LYP/$6-311++G^{**}$ level. To obtain more precise energy result, stationary point energies were calculated at the CCSD(T)/$6-311++G^{**}$//B3LYP/$6-311++G^{**}$ level. $SiF_2+HNCO{\rightarrow}IM3{\rightarrow}TS5{\rightarrow}IM4{\rightarrow}TS6{\rightarrow}OSiF_2CNH(P3)$ was the main channel with low potential energy, $OSiF_2CNH$ was the main product. The analyses for the combining interaction between $SiF_2$ radical and HNCO with the atom-in-molecules theory (AIM) have been performed.

• Bulletin of the Korean Chemical Society
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• v.35 no.3
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• pp.839-844
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• 2014

The gas-phase radical-radical reaction $O(^3P)$ + $C_2H_5$ (ethyl) ${\rightarrow}$ $H(^2S)$ + $CH_3CHO$(acetaldehyde) was investigated by applying a combination of vacuum-ultraviolet laser-induced fluorescence spectroscopy in a crossed beam configuration and ab initio calculations. The two radical reactants $O(^3P)$ and $C_2H_5$ were respectively produced by photolysis of $NO_2$ and supersonic flash pyrolysis of the synthesized precursor azoethane. Doppler profile analysis of the nascent H-atom products in the Lyman-${\alpha}$ region revealed that the average translational energy of the products and the average fraction of the total available energy released as translational energy were $5.01{\pm}0.72kcalmol^{-1}$ and 6.1%, respectively. The empirical data combined with CBS-QB3 level ab initio theory and statistical calculations demonstrated that the title exchange reaction is a major channel and proceeds via an addition-elimination mechanism through the formation of a short-lived, dynamical addition complex on the doublet potential energy surface. On the basis of systematic comparison with several exchange reactions of hydrocarbon radicals, the observed small kinetic energy release can be explained in terms of the loose transition state with a product-like geometry and a small reverse activation barrier along the reaction coordinate.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.9C
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• pp.1279-1288
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• 2004

In this paper, the DMR(Digital Microwave Radio) system-based OFDM(Orthogonal Frequency Division Multiplexing) scheme in microwave channel environments has been proposed and system performances have been evaluated. The existing single carrier DMR system has a complex system structure due to using high-level QAM(Quadrature Amplitude Modulation) modulation scheme and so charmel capacity is limited by sensitive effects from fading. Therefore, in the proposed DMR system, it uses that the OFDM scheme for enhancement of fading distortion and also uses that the band-limited pulse shaping filter instead of windowing for no additional data such as GI/GB and for using efficient of IFFT/FFT block. The performance of OFDM/QPSK-DMR system and single carrier DMR system are analysed by computer simulation using two-ray model under the microwave channel environments The computer simulation results confirm that the fade margin of the proposed OFDM/QPSK-DMR system is highly increased as the number of sub-carriers is larger.

• International Journal of Fuzzy Logic and Intelligent Systems
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• v.8 no.1
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• pp.75-81
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• 2008

This paper presents a top-down approach to implement an MPEG-2 audio encoder in VLSI. As the algorithm of an MPEG-2 audio encoder is heavy-weighted and heterogeneous(to be mixture of several strategies), the encoder design process is undertaken carefully from the algorithmic level to the architectural level. Firstly, the encoding algorithm is analyzed and divided into sub-algorithms, called tasks, and the tasks are partitioned in the way of reusing the same designs. Secondly, the partitioned tasks are scheduled and synthesized to make the most efficient use of time and space. In the end, a real-time 5 channel MPEG-2 audio encoder is designed which is a heterogeneous multiprocessor system; two hardwired logic blocks and one specialized DSP processor.

• Nuclear Engineering and Technology
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• v.35 no.2
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• pp.91-107
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• 2003

Since DBA(Design Basis Accidents) has been studied rather separately from SA(Severe Accidents) in the conventional nuclear reactor safety analysis, the thermal hydraulics during transition between DBA and SA has not been identified so much as each accident itself. Thus, in this study, the thermal hydraulic behavior from DBA to the commencement of SA has been experimentally and analytically investigated for the long-term cooling phase of LB-LOCA(Large-Break Loss-of-Coolant Accident). Experiments were conducted for both cases of the loop seal open and closed in an integral test loop, named as SNUF (Seoul National University Facility), which was scaled down to l/6.4 in length and 1/178 in area of the APR1400 (Advanced Power Reactor 1400MWe). The core mixture level was a main measured value since it took major role in the fuel heat-up rate, the location of fuel melting initiation and the channel blockage by melting material during SA. Experimental results were compared to MAAP4.03 to assess its model of calculating the core mixture level. MAAP4.03 overestimates the core two- phase mixture level because sweep-out and spill-over and the measures to simulate the status of loop seal are not included, which is against the conservatism. Thus, it is recommended that MAAP4.03 should be improved to simulate the thermal hydraulic phenomena, such as sweep-out, spill-over and the status of loop seal.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.4
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• pp.335-344
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• 2024

Diphenyleneiodonium (DPI) has been widely used as an inhibitor of NADPH oxidase (Nox) to discover its function in cardiac myocytes under various stimuli. However, the effects of DPI itself on Ca²⁺ signaling and contraction in cardiac myocytes under control conditions have not been understood. We investigated the effects of DPI on contraction and Ca²⁺ signaling and their underlying mechanisms using video edge detection, confocal imaging, and whole-cell patch clamp technique in isolated rat cardiac myocytes. Application of DPI suppressed cell shortenings in a concentration-dependent manner (IC₅₀ of ≅0.17 µM) with a maximal inhibition of ~70% at ~100 µM. DPI decreased the magnitude of Ca²⁺ transient and sarcoplasmic reticulum Ca²⁺ content by 20%-30% at 3 µM that is usually used to remove the Nox activity, with no effect on fractional release. There was no significant change in the half-decay time of Ca²⁺ transients by DPI. The L-type Ca²⁺ current (I_Ca) was decreased concentration-dependently by DPI (IC₅₀ of ≅40.3 µM) with ≅13.1%-inhibition at 3 µM. The frequency of Ca²⁺ sparks was reduced by 3 µM DPI (by ~25%), which was resistant to a brief removal of external Ca²⁺ and Na⁺. Mitochondrial superoxide level was reduced by DPI at 3-100 µM. Our data suggest that DPI may suppress L-type Ca²⁺ channel and RyR, thereby attenuating Ca²⁺-induced Ca²⁺ release and contractility in cardiac myocytes, and that such DPI effects may be related to mitochondrial metabolic suppression.

• Journal of the Korean Society of Clothing and Textiles
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• v.40 no.6
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• pp.1045-1061
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• 2016

This study clarifies differences in attitudes toward the Omni-Channel service (Pintech service, Beacon service, and Click and Collect service) and fashion consumption behavior among four clusters grouped by level of technology readiness. An online survey was conducted; 572 individuals between 20 and 30 years of age were collected, but only 539 were used. Factor analysis, cluster analysis, descriptive statistics, ANOVA, and frequency analysis were adopted to analyze data using SPSS 20.0. The results are as follows. Technology readiness was divided into four factors: optimism, innovativeness, discomfort, and insecurity. Participants were divided into four groups according to four sub-factors of technology readiness: brave adopters, optimistic laggards, indifferent adopters, and critical adopters. These groups showed significant differences in attitudes toward the Omni-Channel service and fashion consumption behavior. Critical adopters and brave adopters recognized the value of the Omni-Channel service and had more positive attitudes toward it than other groups. Critical adopters also better perceived the risk of service with new technology that showed higher fashion innovativeness and monthly consumption of fashion products than other groups. We inferred that the indifferent adopters did not use the Omni-Channel service or services offered by fashion retailers as much as other groups because indifferent adopters were less interested in both the Omni-Channel service and fashion consumption behavior than other groups. Optimistic laggards viewed the Omni-Channel service optimistically, despite perceptions of high risks to accompanying it and a low intent to use it. The results of this study assisted in the formation of a theoretical framework of consumer behavior associated with the Omni-Channel, which is an emerging issue in research related to distribution. The results can help fashion industries that operate consumer-oriented marketing based on Omni-Channel strategies.

• The Journal of the Acoustical Society of Korea
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• v.21 no.1
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• pp.37-41
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• 2002

In this paper, we made shorter EDT(early decay time) of room reverberation curve using multiple-channel. The speech signal was processed inverse filtering with full-band and sub-band in the basis MINT, and then the multiple-channel adaptive filters were used LMS (Least Mean Square) and NLMS (Normalized Least Mean Square) algorithm. Experimental results, we could get 1/3 of time reduction at 20dB level in the reverberation curve using full-band NLMS when two microphones were used. Also, it is shown that the speech articulation was improved 80% from the test listeners with the speech, which was to shorten EDT by MINT in the subjective assessments using real room impulse response.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.38 no.2
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• pp.169-178
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• 2001

The demand for high-resolution images is gradually increasing, whereas many imaging systems have been designed to allow a certain level of aliasing during image acquisition. Thus, digital image processing approaches have recently been investigated to reconstruct a high-resolution image from aliased low-resolution images. However, since the sub-pixel motion information is assumed to be accurate in most conventional approaches, the satisfactory high-resolution image cannot be obtained when the sub-pixel motion information is inaccurate. Therefore, in this paper we propose a new algorithm to reduce the distortion in the reconstructed high-resolution image due to the inaccuracy of sub-pixel motion information. For this purpose, we analyze the effect of inaccurate sub-pixel motion information on a high-resolution image reconstruction, and model it as zero-mean additive Gaussian errors added respectively to each low-resolution image. To reduce the distortion we apply the modified multi-channel image deconvolution approach to the problem. The validity of the proposed algorithm is both theoretically and experimentally demonstrated in this paper.

• BMB Reports
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• v.53 no.9
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• pp.484-489
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• 2020

Epilepsy is a neurological disorder characterized by unpredictable seizures, which are bursts of electrical activity that temporarily affect the brain. Cereblon (CRBN), a DCAFs (DDB1 and CUL4-associated factors), is a well-established protein associated with human mental retardation. Being a substrate receptor of the cullin-RING E3 ubiquitin ligase (CRL) 4 complex, CRBN mediates ubiquitination of several substrates and conducts multiple biological processes. In the central nervous system, the large-conductance Ca²⁺-activated K⁺ (BK_Ca) channel, which is the substrate of CRBN, is an important regulator of epilepsy. Despite the functional role and importance of CRBN in the brain, direct injection of pentylenetetrazole (PTZ) to induce seizures in CRBN knock-out mice has not been challenged. In this study, we investigated the effect of PTZ in CRBN knock-out mice. Here, we demonstrate that, compared with WT mice, CRBN knock-out mice do not show the intensification of seizures by PTZ induction. Moreover, electroencephalography recordings were also performed in the brains of both WT and CRBN knockout mice to identify the absence of significant differences in the pattern of seizure activities. Consistently, immunoblot analysis for validating the protein level of the CRL4 complex containing CRBN (CRL4^Crbn) in the mouse brain was carried out. Taken together, we found that the deficiency of CRBN does not affect PTZ-induced seizure.