• Journal of the military operations research society of Korea
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• v.29 no.2
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• pp.26-44
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• 2003

This study Is to forecast the damage of smallpox as a biological weapon and to measure the effect of potential responses (quarantine, vaccination and cure) to the spread of smallpox infection when a smallpox bioterrorism attack occurs. We designed the smallpox spreading simulation model through the literature study on a basis of some existing infectious disease models such as SIR, SEIR model by using Vensim program. In order to evaluate the performance of responses to smallpox, we measure the total infection population, infection sustaining duration, average infection rate and the infection spreading behavior of the smallpox. This study can help those who are related to the bioterrorism forecast the present and possible demage, and take more effective actions for minimizing the damage by smallpox bioterrorism.

• The Journal of Korean Medical History
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• v.30 no.2
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• pp.119-131
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• 2017

GogeumGyeongheomHwalyubang [古今經驗活幼方] is a medical book dedicated to Smallpox, written by YU Sang [柳瑺] in the Joseon Dynasty (late 17th century to the early 18th century). As a smallpox specialist for the Joseon royal family, YU Sang was well-reputed after successfully treating smallpox of three of the 27 Joseon kings. There are four features of this book. First, the causes for smallpox are roughly recorded. Second, YU Sang emphasized the distinction between patients who could or could not be cured. Third, the herbs related to the treatment of smallpox are selected and organized separately. Fourth, YU Sang discusses the contents of diverse medical books and his own experiences. Conclusion : YU Sang's significant knowledge of smallpox treatment is well presented in his book, GogeumGyeongheomHwalyubang and this wealth of experience would have an important role in understanding the development of smallpox treatment in the late Joseon Dynasty.

• The Journal of Korean Medical History
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• v.30 no.1
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• pp.1-9
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• 2017

Although Maejeong-Bogam (梅亭寶鑑) is a manuscript, it has attracted considerable attention from academia because of the clear authorship and relevant treatment methodologies. This article is the result of an extensive study on the author and the contents of the manuscript through the use of various data. This article revealed facts which include: 1) Author HAN Bangryeol (韓昉烈) is a Confucian doctor who lived in Namwon area, Jeolla province of Korea. 2) Dr. HAN's other manuscript of Bongseong-Shinbang (鳳城神方) was written before 1814. 3) Maejeong-Bogam (梅亭寶鑑) collects pediatric medical records only and is focused on outbreaks and treatment of smallpox among children. 4) Smallpox was a national concern in the late Joseon Dynasty and doctors of the day developed corresponding therapies. 5) Smallpox Inoculation was carried out in Jeolla Province as early $19^{th}$ in Korea.

• Journal of Haehwa Medicine
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• v.19 no.2
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• pp.1-12
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• 2011

21th century is a era of new pandemic. We are facing a new challenge and need a new way of approach. But eastern medicine and western medicine is clinging to their own way and have no intention to hear other one's opinion. Before the invention of the vaccination, smallpox has always been a major problem. Intellectuals in every country tried their best to find the treatment for the smallpox, and for Europian, didn't hesitate to borrow some knowledge of the pagon. Romans adopted the Galens concept, running away from the epidemic lesion. Christianity made smallpox Saints, and later adopted Razes heat therapy. But in the 17th century, these methods didn't turn out well, so they needed a new way of approach. By this movement, they had adopted the Chinese inoculation concept and invented a vaccination, By studying the effort of the Europian intellectuals who had tried their best to find the treatment for the smallpox until 17th century, we might get a glimps of wisdom which they had shown us. By this paper we can feel the passion to learn new techniques and their open mind and courage, which might be also needed in the 21th century, era of new pandemic.

• The Journal of Korean Medical History
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• v.25 no.1
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• pp.43-51
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• 2012

Smallpox and measles might be the typical epidemics through Choson Danasty. Especially Sookjong was the first king who suffered from smallpox during the period of his reign. This study was examined critically focused on the Clinical Records about Smallpox which occurred in the 9th year of Sookjong's reign. The clinical records in Seungjeongwon Ilgi("承政院日記") was the main source and the Annals of the Joseon Dynasty was reffered. It tells us that Sookjong caught infectious disease, smallpox spread in town and the whole process of smallpox. Seungmagalgeuntang(升麻葛根湯) and hwadoktang(火毒湯) were given at the early term for treating Sookjong's smallpox, but later on, Bowontang(補元湯) was given for the treatment of smallpox. It showed us the medical view which placed emphasis on the vital force of human body. A dermatologist, Yoo Sang had joined since the beginning of the treatment and Siyakchung(侍藥廳) was established for Sookjong. Sasunghoichuntang(四聖回天湯) which was Chunyoohyung(全有亨)'s prescription showed us enough clinical experience and the ways of treatments. At the same time, the medical culture at that time was well known through the fact that smallpox was taboo among the royal family.

• Journal of Korean Medical classics
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• v.29 no.4
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• pp.37-52
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• 2016

Objectives : The paper seeks to delve into a study of smallpox, specifically as one of the most representative contagious diseases during the Chosun era and how it was treated during that time. The lack of traditional medical texts that deal with smallpox has led this paper to dive into Duchanggyeongheombang. Methods : Everything related to edition and copy, and the author was organized based on pre-existing studies. The copy that is assumed as the original copy was considered and studied. The book was compared to and reviewed with Donguibogam, and the differences between the book and Korean translation were given attention as well. Results : Park Jin-hee is assumed to have authored Duchanggyeongheombang, and it is like that was had access to texts published by the state, one of which includes Donguibogam. He utilized the periods with smallpox outbreaks as his frame of study and put together a series of treatment for different symptoms. To this, he attached various medical charts, and added Korean translation for higher usability. In his book, he placed emphasis on spleen and stomach, but when needed, he did not shy away from using cold and coolness herbs. Conclusions : Duchanggyeongheombang was influenced partially by Donguibogam, but the book was given new life through the author Park Jin-hee's edition. Medical charts were added to increase its usability, and Korean translation was provided for wider audience. Its scope of prescription is very wide, and it provided the reasonings behind its medical judgements based on actual clinical studies instead of being tied down to traditions or taboos.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.22 no.12
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• pp.881-890
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• 2010

As Influenza A virus(H1N1) has been spreading more rapidly around globe, the study on the airborne disease which is transimitted through the respiratory system is on the rise. In this study, the multizone simulation of the public building against bioviolence is performed in the case of unexpected spread of microbial contaminants, such as bioviolence agent, Influenza A, Smallpox, B. anthrax and transport and control characteristics of above three kinds of bioviolence agents are evaluted. Results suggest that Influenza A and Smallpox which has small mean diameter can be more removable than B. anthrax by using high UVGI grade condition and B. anthrax which has large mean diameter can be more removable than Influenza A and Smallpox by using high filter grade condition. Results also suggest that installing a combined air treatment system is more effective to reduce the damage and engineers will use immune building technology for removing the bioviolence agents effectively.

• Journal of Korean Medical classics
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• v.35 no.3
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• pp.59-69
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• 2022

Objectives : The existence of specialized medical texts on a certain disease is reflective of its prevalence of the time. Smallpox and measles were major pediatric diseases, of which previous studies examined the outbreak of measles in late Joseon and the relationship among various specialized texts, and how records of the two diseases in the general medical literature has changed chronologically. Research on the two diseases recorded in different texts written by the same author has not been conducted before. Methods : Examination of the organization of the smallpox and measles parts in the Yosandangsinjipuibangkeumnangjibo and Bojeoksinbang, followed by comparative analysis was undertaken. Results : While the two texts show great similarity in the general contents of smallpox and measles, there was difference in the way they were written. In the case of the Yosandangsinjipuibangkeumnangjibo the author lists referenced literature, while in the Bojeoksinbang he does not. Also, compared to the Yosandangsinjipuibangkeumnangjibo, the Bojeoksinbang has detailed titles for the contents in both introduction and the detailed parts, while in the Bojeoksinbang there are contents that could not be found in the Yosandangsinjipuibangkeumnangjibo, along with more pattern differentiation in the former. Conclusions : The Yosandangsinjipuibangkeumnangjibo which was published in May of 1806 is a general type of medical text, in which the part on pediatrics is positioned in the first two volumes out of the entire 12 volumes, indicative of the author's emphasis on pediatric disease. The Bojeoksinbang which was published in December of 1806 discusses in-depth theories on smallpox and measles out of all pediatric disease, from which we can glimpse a specialized field of pediatrics in the late Joseon period.

• The Journal of Korean Medical History
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• v.31 no.2
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• pp.41-52
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• 2018

In this study, we research the tendency of medical text publication by examining the period of the great measles outbreak and the period of the publication of specialized smallpox texts. Using the National Institute of Korean History database for the Annals of Joseon Dynasty, the Daily Records of Royal Secretariat of Joseon Dynasty and Bibyeonsadeunglok, we will compare all records of measles occurrence. Measles and smallpox (Majin in Korean) have similar symptoms and treatment methods. In East Asia, when measles occurred it spread to Joseon and Japan, which are verified by records of the Annals of Joseon Dynasty, the Daily Records of Royal Secretariat of Joseon Dynasty and Bibyeonsadeunglok. The medical books related to measles are; Ryuhasinbang, Majinpyeon, Geupyubang, Yimsinyeokbang, Eulmisinjeon, Majingbang, Jinyeokbang, Magwahoetong, Majingibang, Susengsingam, Hongjinsinbang. Measles and Majin are the same disease. During the period of measles occurrence, measles-related medical books were published, and this relation of measles occurrence and measles-related medical text publication is verified by several national records.

• Journal of applied mathematics & informatics
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• v.41 no.5
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• pp.1017-1035
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• 2023

In this paper, we construct a monkeypox model which is similar to smallpox infection. It is caused by a monkeypox virus which is related to Poxviridae family. It will occur mostly in West African communities and in remote Central. We develop a system of differential equations for an SEIR (Suspected, Exposed, Infected and Recovered) model and analyze the outbreak of monkeypox disease and its effect on United States(US) population. We establish theorems on asymptotical stability conditions for endemic equilibrium and disease-free equilibrium. The basic reproduction number R₀ has been determined using next generation matrix. We expect that this study will be effective at controlling monkeypox spread in United States. Our goal is to see whether monkeypox can be controlled and destroyed by smallpox vaccination. We find that monkeypox is controllable and can be fully destroyed in disease free state by vaccination. However, in the endemic state, monkeypox cannot be destroyed by vaccination alone.