• 토지주택연구
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• 제8권3호
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• pp.189-200
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• 2017

The work breakdown structure and the precedence relations by work activity are very important because they are the basic data for estimating the construction duration in the construction work. However, there is no standard to accurately estimate the construction duration since the size of the school facilities construction is smaller than the general construction work. Therefore, some schools are unable to open in March or September and the delay of the construction duration can cause damage to the students. To solve this problem, this study developed a work breakdown structure of school facilities construction work and analyzed the precedence relations by work activities. The work breakdown structure of the school facilities construction is composed of three steps. The operations corresponding to level 1 and level 2 are as follows. (1) 2 preparatory work categories; preparation period and temporary construction. (2) 17 architectural work categories; temporary construction, foundation & pile work, reinforced concrete work, steel roof work, brick work, plaster work, tile work, stone work, waterproof construction, wood work, interior construction, floor work, metal work, roof work, windows construction, glazing work and paint construction. (3) 7 mechanic and fire work categories; outside trunk line work, plumbing work, air-conditioning equipment work, machine room work, city gas plumbing work, sanitation facilities and inspection & test working. (4) 4 civil work categories; wastewater work, drainage work, pavement work and other work. (5) 1 landscaping work categories; planting work. The work breakdown structure was derived from interviews with experts based on the milestones and detailed statements of existing school facilities. The analysis of precedence relations by school facilities work activity utilized PDM(Precedence Diagramming Method)which does not need a dummy and the relations were applied using FS(Finish to Start), FF(Finish to Finish), SS(Start to Start), SF(Start to Finish). The analysis of this study shows that if one work activity is delayed, the entire construction duration may be delayed because the majority of the works are FS relations. Therefore, it is necessary to use the Lag at the appropriate time to estimate the standard construction duration of the school facility construction. Lag is a term used only in the PDM method and it is used to define the relationship between the predecessor and the successor in creating the network milestone. And it means the delay time applied to the two work activities. The results of this study can reasonably estimate the standard construction duration of school facilities and it will contribute to the quality of the school facilities construction.

• 한국수학교육학회지시리즈D:수학교육연구
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• 제17권1호
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• pp.1-14
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• 2013

Stochastic phenomena induce us to construct a probability model and structure our thinking; corresponding models help us to understand and interpret the reality. They in turn equip us with tools to recognize, reconstruct and solve problems. Therefore, various implications in terms of methodology as well as epistemology naturally flow from different adoptions of models for probability. Right from the basic scenarios of different perspectives to explore reality, students are occasionally exposed to misunderstanding and misinterpretations. With realistic examples a multi-faceted image of probability and different interpretation will be considered in mathematical modelling activities. As an exploratory investigation, mathematical modelling activity for probability learning was elaborated through semiotic analysis. Especially, the coherence structure in mathematical modelling discourse was reviewed form a semiotic perspective. The discourses sampled from group activities were analyzed on the basis of semiotic perspectives taxonomical coherence relations.

• Archives of Pharmacal Research
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• 제20권1호
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• pp.80-84
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• 1997

Substituted cinnamoyl-tyramine derivatives were synthesized by DCC-coupling of substituted cinnamic acid with tyramine or tyramine methyl-1-ether to evaluate PAF-receptor binding antagonistic activities and inhibitory activities on PAF-induced platelet aggregation with interest on structure-activity relations. The results show that 3,4-dimethoxy-cinnamoyl tyramine-amide or its methyl ether have significant PAF-receptor binding antagonistic activity and platelet anti-aggregatory activities.

• Archives of Pharmacal Research
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• 제11권1호
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• pp.33-40
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• 1988

Two new nitro analogs of tranylcypromine, (E)-2-(p-nitrophenyl)cyclopropylamine ((E)-p-NTCP) and (E)-2-(m-nitrophenyl)cyclopropylamine ((E)-m-NTCP) were synthesized in order to examine the effect of aromatic nitro substitution on the MAO-inhibitory activity of 2-phenylcyclopropylamines. The compounds were obtained by treating t-butyl (E)-2-(p-nitrophenyl) cyclopropanecarbamate and t-butyl (E)-2-(m-nitrophenyl)cyclopropanecarbamate with p-toluenesulfonic acid in $CH_3$CN. Inhibitions of rat brain mitochondrial MAO-A and B by the compounds were examined using serotonin and benzylamine as the substrate at both in vitro and ex vivo levels. It was found from in vitro measurements that (E)-p-NTCP at $6.0{\times}10^{-5}M$ elicited merely 22.5% inhibition against MAO-B without any effect on MAO-A. In contrast, (E)-m-NTCP showed fair degrees of inhibitions of MAO-A and B with $IC_{50}$ values, $2.5{\times}10^{-7}M\;and\;1.4{\times}10^{-6}M$, respectively. It was also noted from (E)-m-NTCP that m-nitro substitution caused a shift of selectivity of the inhibition toward MAO-A. According to ex vivo measurements at 1.5, 3, 6, and 12 hr following the administration of a dose of 0.015 mmol/kg, i.p. to the rats, the inhibition percents of MAO-A by (E)-m-NTCP were 58.6, 63.7 63.6, and 46.6%, slightly lower than those observed by tranylcypromine. Whereas, (E)-m-NTCP at the same dose level did not show significant inhibitions against both MAO-A and MAO-B. Possible reasons for the difference in potencies between (E)-m-NTCP and (E)-p-NTCP were sought in relation to differing electron withdrawing effects of m- and p-substituents which will influence electron density of the side chain amino functions and the partitions.

• 생약학회지
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• 제17권2호
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• pp.168-177
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• 1986

Bioassay-directed isolation has yielded some cytotoxic substances against L1210 cell from the Korean traditional medicine. These include 5,2'-dihydroxy-6,7,8,6'-teramethoxyflavone $(IV,\;scutellaria\;root,\;ED_{50}\;=\;1.7\;{mu}g/ml)$, 7-geranyloxycoumarin $(XXXII,\;poncirus\;fruit,\;10.2\;{mu}g/ml) $and panaxydol $(I,\;white\;ginseng,\;0.03\;{mu}g/ml)$. IV, XXXII and their derivatives were synthesized in the purpose of in vivo tests and for observation of structure-activity relations. Among the flavone derivatives, 5,2',6'-trihydroxy-6,7,8-trimethoxy flavone (XVIII), 5-hydroxy-6,7,8-trimethoxy-6'-benzyloxyflavone (XVII) and 5,8-dihydroxy-6,7-dimethoxyflavone (X) showed the cytotoxicity which has no correlation to the flavone structures. Of the coumarins synthesized, 7,8-dihydroxycoumarin (XXVI), 6-7-dihydroxycoumarin (XXIX) and 6-hydroxy-5,7-dimethoxycoumarin (XXXI) showed considerable activities. Acetylated XXXI has moderate activity $(ED_{50}=17.2\;{mu}g/ml)$. Monobydroxycoumarins or their methyl and allyl ether were inactive. IV inhibits the growth of the solid form of S-180 by 70% at 40 mg/kg and shows T/C of 166% on the ascitic S-180 at 40 mg/kg. It strongly inhibits the activity of the membrane bounded ATPase from L1210 cell. The most cytotoxic fraction of the antitumor materials studied is the one from the trichosanthes root showing $ED_{50}=0. 0003\;{mu}g/ml$ against L1210 cell. This fraction, obtained from ethyl acetate extract, showed T/C of 130 and 135%, on ICR mice bearing S-180 and $BDF_1$ mice bearing L1210 at 10 mg/kg and 7.5 mg/kg, respectively.

• 지역사회간호학회지
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• 제15권2호
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• pp.308-322
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• 2004

Purpose: 'The purpose of the present study was to understand students' experiences from their standpoint, to identify relevant variables and to examine into their relations by analyzing and describing what phenomenon 'nursing students' visiting ambulatory bathing service' is, what are the reasons for the phenomenon, and what interactions are in the phenomenon. Method: The subjects were thirteen students. Data were collected through in-depth interviews and analyzed by Strauss and Corbin's analysis method. Result: With regard to ambulatory bathing service, participants responded 'lack of education', 'inexperienced personal relations' and 'disappointment with recipients families'. They recognized 'burden' and 'compassion'. The intensity of generated 'burden' and 'compassion' was determined by volunteering persons, the degree of health care service, recipients' response and interaction of climate. When 'burden' and 'compassion' were generated, participants selected their own coping strategies. Strategies in the situation of 'burden' and 'compassion' were significantly influenced by 'burden' and 'compassion' and structural situation - 'mutual relation structure,' 'volunteers' capability,' 'the degree of volunteering guidance,' 'community participation,' 'recipients' environment,' 'information sharing,' 'special vehicle equipment' and 'economical burden.' Strategies include' service training,' 'receiving volunteering training,' 'preliminary service preparation,' 'volunteering.' 'connection to local medical center,' 'intention,' 'information sharing,' 'passive response to recipients' appreciation' and 'the understanding of publicity'. The results of selected 'burden' and 'compassion' are described with 'worthiness' and 'cohesion' as follows. Conclusion: This study is significantly meaningful in that it examined bathing service welfare in its initial stage. There are not much outcome from previous studies. However. it is meaningful that this study intended to develop theories on the nature of experiences and the relations among concepts derived from the visiting ambulatory bathing service process of nursing students. Professors who taught social volunteering in universities understood the experience of nursing students who did the visiting ambulatory bathing service. Consequently, professors will provide an effective instruction to enable these students to carry out visiting ambulatory bathing services efficiently in order to meet demands when they conduct the services. For the volunteering service activity in major-related fields among college students' social volunteering activities, they recognized the necessity of systematic education and preparation.

• 한국주거학회논문집
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• 제21권4호
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• pp.23-31
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• 2010

This study aims to examine the educational function space of university dormitories at local universities with corridor centered structure in Honam area regions based on direct and indirect parameters on the whole satisfaction of users in residential environment factors and personal characteristics. First, according to relations among parameters, educational and cultural activities of four major activities within the dormitory had indirect influences on social activities, eating and sleeping activities had no direct influence on other activities. And social activity had direct influence on the general satisfaction as an important parameter and educational and cultural activities had indirect influence on the whole satisfaction through social activities. Detailed results show that, in the first educational activities directly affecting the lighting and air conditioning facilities (0.22), safety (0.326), Territoriality (0.327), the space density (-0.167), directions (-0.166) and yeohyang having personal characteristics and the safety of the second cultural activities (0.183), Territoriality (0.361), Aesthetics (-0.13) and the personal characteristics Sex (-0.179), the direct effect, third, and erosion has a direct impact on activity The flexibility of the space factor (-0.128) and Territoriality (0.38) and the personal characteristics grade (0.172), respectively. Fourth in social activities directly affecting the pathfinding (-0.104), and parameter, education (0.388) and cultural activities (0.445), and some of the factors affecting the indirect lighting and air conditioning facilities, safety, and Territoriality, the space density, directions, grade, they could influence through educational activities to be analyzed. That is, territoriality in educational function space is the important factor that users react very sensitively in educational, eating and sleeping activities and educational function space must secure area and division considering personal and public use as the space accommodating activity which is lacking in unit residential space. Accordingly, the safety of educational function space in university dormitory is considered as the fundamental safety matter on the fire prevention, hygiene and cleanness for users in the satisfaction of educational and cultural activities.

• 대한화학회지
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• 제34권4호
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• pp.331-339
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• 1990

cis-diamminedichloroplatinum (II)에서 아민리간드가 변화할 때, 항암성과 백금원자의 전자구조 사이의 관계를 연구하였고, 또 이러한 착물과 DNA base인 1-methylcytosine의 상호작용에 대한 메카니즘을 알기 위해서 백금(II)착물들을 분자궤도함수론적으로 연구하였다. 그 결과, 백금착물에서 중심금속의 atomic charge가 항암성에 영향을 미치고 있음을 알았다. 또한 백금착물과 1-methylcytosine의 결합은 리간드에서 금속원자로 전하이동을 하였고, 이 때 Pt(II)의 6p-orbital이 중요한 하고 있음을 발견한다. Pt-N3결합성은 $\alpha$ 와 $\pi$ 성분을 포함하고 있으며, 실험한 값과 비교할 때 비교할 때 항암성이 큰 백금착물일수록 Pt-N3 결합이 강하게 형성하고 있었다.

• 재무관리연구
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• 제27권1호
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• pp.89-120
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• 2010

본 연구는 1997년 1월 1일부터 2008년 12월 31일까지 한국거래소의 유가증권시장과 코스닥시장에 상장된 기업을 대상으로 소유구조와 현금보유간의 관계를 실증분석 하였으며, 주요한 분석결과는 다음과 같다. 대주주 지분율이 클수록 대주주들이 이사회 참여를 통한 경영권 통제 등을 통하여 수익성이 낮은 현금보유를 증가시키는 방향으로 소액주주의 이익을 침해할 수 있다. 1대주주와 2대주주 간의 지분율 차이가 증가할수록, 그리고 대주주들 간의 소유집중도가 증가할수록 현금보유가 증가한다. 그리고 경영자지분율은 현금보유에 비선형적으로 영향을 미친다. 다시 말해, 경영자지분율이 낮은 단계에서는 이익침해가설에 따라 현금보유에 양(+)의 영향을 미치지만, 경영자지분율이 일정 수준 이상으로 증가하면 이해일치가설에 따라 음(-)의 영향을 미치며, 경영자지분율이 매우 높은 수준으로 증가하면 다시 이익침해가설에 따라 양(+)의 영향을 미친다. 그리고 소유자지배기업은 경영자지배기업보다 대주주들이 현금보유에 미치는 영향력이 상대적으로 증가하여 현금보유를 증가시킬 수 있다. 이러한 결과는 한국기업의 현금보유는 주로 상충이론과 자금조달순서 이론으로 설명할 수 있으나, 대리인 이론으로도 부분적으로 설명할 수 있으며, 이는 대주주들이 소액주주와 균등한 혜택이 분배되는 재무정책을 기피하고 소액주주의 희생 하에 사적 이익을 취할 가능성이 있음을 시사한다. 따라서 우리나라에서도 대주주가 소액주주의 이익을 침해하는 행위를 예방하고, 소액주주의 이익을 보호할 수 있는 제도적 장치와 소유집중도를 완화시킬 수 있는 소유구조 정책이 필요하다고 생각한다.

• 응용통계연구
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• 제22권2호
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• pp.249-260
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• 2009

정책수단과 장래 발생할 사건 간에 시차가 존재할 때 미래의 상태를 예측하는 데 유용한 선행지표의 개발에 다양한 방법들이 모색되어 왔다. 미래의 상황전개에 대응하는데 필요한 정보가 조기에 제공된다면 최근과 같은 경제위기의 폭은 크게 감소될 수 있을 것이다. 그간 금융환경이 변화하면서 금융변수와 실물경제활동 간에 관계가불안정해지고 괴리가 심화됨에 따라 본 연구에서는 미래의 경기동향을 미리 예측할 수 있는 국내외 금리변수들의 예측 능력을 추정해 비교 평가해 보았다.