• Title/Summary/Keyword: Structure and function

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Association of Single Nucleotide Polymorphism (SNP) in the PGK 2 Gene with Growth Traits in Pigs (돼지 PGK 2 유전자의 단일염기다형성 및 성장 형질과의 연관성 구명)

  • Jang, Hong-Chul;Kim, Sang-Wook;Lim, Da-Jeong;Kim, Jae-Young;Cho, Kyu-Ho;Kim, Myung-Jick;Lee, Ji-Woong;Choi, Bong-Hwan;Kim, Tae-Hun
    • Journal of Animal Science and Technology
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    • v.53 no.1
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    • pp.15-22
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    • 2011
  • The purpose of this study was to analyse of association between growth traits and single nucleotide polymorphisms (SNPs) polymorphism of phosphoglycerate kinase 2 (PGK 2) gene in pigs. The birth weight of piglet influences on weaning weight and survival rate that are import economic traits in pig industry. Also, these growth traits are representative factor to decrease a period getting to marketing weight as well as growth rate in pig. The PGK 2 is an isozyme that catalyzes the first ATP-generating step in the glycolytic pathwayand important enzyme related with energy metabolism. Twenty of SNPs were discoveredby genome structure analysis that compares the sequence on promoter and transcription region of PGK 2 gene in porcine chromosome 7. An association between PGK 2 SNPs and growth traits was analyzed in $F_2$ reciprocal-crossbred population between korean native pig (KNP) and Landrace. Association analysis indicated that polymorphism of the PGK 2 gene promoter region has significant effects on weight at birth (p<0.01) and weight at 3 weeks of age (p<0.0001). These results suggest that PGK 2 gene polymorphism was associated with energy metabolism and physiological function of growth in pig.

A Study on the Dynamic Amplification Characteristics of the Domestic Seismic Observation Sites using Shear- and Coda-Wave (S파 및 Coda파를 이용한 국내 관측소지반의 동적 증폭특성에 관한 연구)

  • Kim, Jun-Kyoung
    • Tunnel and Underground Space
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    • v.19 no.5
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    • pp.432-439
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    • 2009
  • For more reliable estimation of seismic source, attenuation properties and dynamic ground property, site amplification function should be considered. Among various estimation methods, this study used the Nakamura's method (1989) for estimating site amplification characteristics. This method was originally applied to the surface waves of background noise and therefore there are some limitations in applying to general wave energy. However, recently this method has been extended and applied to the S wave energy successfully. This study applied the method to S wave and Coda wave energy, which is equivalent to the backscattered S wave energy. We used more than 60 observed ground motions from 5 earthquakes which were occurred recently, with magnitude range from 3.6 to 5.1. Each station showed characteristic site amplification property in low-, high- and resonance frequencies. Some of the stations showed as high as 4 times of site amplification in the range of specific frequencies, which may imply abnormal small scale geologic strata below the station or development of various trapped modes in the basin structure. Moreover, removal of site amplification can give us more reliable seismic source and attenuation parameters, addition to the seismic hazard estimation.

Aeroelastic Tailoring of a Forward-Swept Wing Using One-dimensional Beam Analysis (1차원 보 해석을 활용한 전진익 항공기의 복합적층 날개 공력탄성학적 테일러링)

  • Choi, JaeWon;Lim, ByeongUk;Lee, SiHun;Shin, SangJoon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.48 no.8
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    • pp.555-563
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    • 2020
  • Foward-swept wings are known to possess superior aerodynamic performance compared to the conventional straight wings. However major concerns regarding forward-swept wings include divergence at lower airspeeds which require careful consideration at the design stage. As an endeavor to overcome such drawbacks, aeroelastic tailoring is attempted. In order to find an optimal ply sequence, recursive aeroelastic analyses is conducted and one-dimensional beam analysis coupled with simple aerodynamics is used for the improved computational efficiency and modelling convenience. The analysis used in this paper, DYMORE and analytic formula, both use one-dimensional beam model for the structure. Cross-sectional analysis for multi-cell NACA0015 airfoil section is conducted using VABS and oblique function is used for the sweep angle. Throughout the present aeroelastic tailoring, the maximum divergence speed of 290.2m/s is achieved which is increased by approximately 43% than that for the conventional ply configuration.

A Historical, Mathematical, Psychological Analysis on Ratio Concept (비 개념에 대한 역사적, 수학적, 심리적 분석)

  • 정은실
    • School Mathematics
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    • v.5 no.4
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    • pp.421-440
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    • 2003
  • It is difficult for the learner to understand completely the ratio concept which forms a basis of proportional reasoning. And proportional reasoning is, on the one hand, the capstone of children's elementary school arithmetic and, the other hand, it is the cornerstone of all that is to follow. But school mathematics has centered on the teachings of algorithm without dealing with its essence and meaning. The purpose of this study is to analyze the essence of ratio concept from multidimensional viewpoint. In addition, this study will show the direction for improvement of ratio concept. For this purpose, I tried to analyze the historical development of ratio concept. Most mathematicians today consider ratio as fraction and, in effect, identify ratios with what mathematicians called the denominations of ratios. But Euclid did not. In line with Euclid's theory, ratio should not have been represented in the same way as fraction, and proportion should not have been represented as equation, but in line with the other's theory they might be. The two theories of ratios were running alongside each other, but the differences between them were not always clearly stated. Ratio can be interpreted as a function of an ordered pair of numbers or magnitude values. A ratio is a numerical expression of how much there is of one quantity in relation to another quantity. So ratio can be interpreted as a binary vector which differentiates between the absolute aspect of a vector -its size- and the comparative aspect-its slope. Analysis on ratio concept shows that its basic structure implies 'proportionality' and it is formalized through transmission from the understanding of the invariance of internal ratio to the understanding of constancy of external ratio. In the study, a fittingness(or comparison) and a covariation were examined as the intuitive origins of proportion and proportional reasoning. These form the basis of the protoquantitative knowledge. The development of sequences of proportional reasoning was examined. The first attempts at quantifying the relationships are usually additive reasoning. Additive reasoning appears as a precursor to proportional reasoning. Preproportions are followed by logical proportions which refer to the understanding of the logical relationships between the four terms of a proportion. Even though developmental psychologists often speak of proportional reasoning as though it were a global ability, other psychologists insist that the evolution of proportional reasoning is characterized by a gradual increase in local competence.

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RMCS Plan and the Embodiment for the Home Network Service which is Safeent (안전한 Home Network 서비스를 위한 RMCS 설계 및 구현)

  • Sun, Jae-Hoon;Lee, Dong-Hwi;J. Kim, Kui-Nam
    • Convergence Security Journal
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    • v.5 no.2
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    • pp.19-27
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    • 2005
  • As home network is increasing to use, home network industry is developing too. Also, it is to be a popular subject in the network's topics. In this reasons, home network become a important thing because home gateway function is working between access network and home network. In the home network, it relates on the personal computer, home pad, and digital television. But, home gateway is not prepared standard point about techniques. Therefore, many kind of technique want to try for developing of home gateway's functions. Usually, we use ID/PASSWORD method in network control system. But, we found a lot of problems about classical network system while we experienced Jan/25 big trouble. We are considering about that home network system are using same network net. Therefore, seriously we have to check about security and safety at the home network's environment. This report focus on the home network's environment to control for using and efficiency and then it wants to find ways to protect from the internal and external attacks. Existing ID/PASSWORD method it used a electronic signature and the security against the approach from of external watch, the MIB structure of role base and the security of the Home network which leads the authority control which is safe even from the Home network inside it strengthened it used compared to it proposed.

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Dimensional change of the healed periosteum on surgically created defects

  • Cho, Eun-Hee;Park, Jung-Chul;Cha, Jae-Kook;Kim, Yong-Tae;Jung, Ui-Won;Kim, Chang-Sung;Choi, Seong-Ho;Kim, Chong-Kwan
    • Journal of Periodontal and Implant Science
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    • v.41 no.4
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    • pp.176-184
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    • 2011
  • Purpose: The final goal of regenerative periodontal therapy is to restore the structure and function of the periodontium destroyed or lost due to periodontitis. However, the role of periosteum in periodontal regeneration was relatively neglected while bone repair in the skeleton occurs as a result of a significant contribution from the periosteum. The aim of this study is to understand the histological characteristics of periosteum and compare the native periosteum with the repaired periosteum after elevating flap or after surgical intervention with flap elevation. Methods: Buccal and lingual mucoperiosteal flaps were reflected to surgically create critical-size, "box-type" (4 mm width, 5 mm depth), one-wall, intrabony defects at the distal aspect of the 2nd and the mesial aspect of the 4th mandibular premolars in the right and left jaw quadrants. Animals were sacrificed after 24 weeks. Results: The results from this study are as follows: 1) thickness of periosteum showed difference as follows (P<0.05): control group ($0.45{\pm}0.22$ mm)> flap-elevation group ($0.36{\pm}0.07$ mm)> defect formation group ($0.26{\pm}0.03$ mm), 2) thickness of gingival tissue showed difference as follows (P<0.05): defect formation group ($3.15{\pm}0.40$ mm)> flap-elevation group ($2.02{\pm}0.25$ mm) > control group ($1.88{\pm}0.27$ mm), 3) higher cellular activity was observed in defect formation group and flap-elevation groups than control group, 4) the number of blood vessles was higher in defect formation group than control group. Conclusions: In conclusion, prolonged operation with increased surgical trauma seems to decrease the thickness of repaired periosteum and increase the thickness of gingiva. More blood vessles and high cellular activity were observed in defect formation group.

A Study on the Improvement of the Connection between Port Space and Hinterland Using FBCs (FBCs를 활용한 항만공간과 항만배후지의 연계성 강화에 관한 연구)

  • Hwang, Sun-Ah;Kim, Jong-Gu
    • Journal of Navigation and Port Research
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    • v.41 no.4
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    • pp.215-228
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    • 2017
  • Taking a look at recent trends of port cities, many port cities in the world have been shedding new light on the function being kept by existing port spaces, caused by changes of industrial structure according to the stream of the times, developments of surrounding areas, and etc., and we can see that its meaning also has been changing. However, in case of domestic port spaces they are in the real situation not responding to those movements quickly. Therefore, unlike the existing zoning system dividing functionally urban spaces according to use simply, in this study FBCs getting the timelight recently as a system capable of reflecting spatial characteristics at the maximum have been utilized as a measure for solving current problems of urban spaces. The purpose of this study is to propose the direction of urban planning approach that harmonizes the whole harbor space by strengthening the interlinkage between heterogeneous spaces of port area and port area using FBCs. FBCs are institutional devices that are proposed and implemented in the United States to reflect the unique characteristics of the space, that is, the location and the uniqueness, and the pedestrian-oriented space planning.

Thermal and chemical stability evaluation of white ceramic pigment for digital inkjet printing (디지털 잉크젯 프린팅용 흰색 세라믹 안료의 고온 및 화학적 안정성 평가)

  • Kwon, Jong-Woo;Lee, Ji-Hyeon;Lee, Jong-Heun;Hwang, Kwang-Taek;Kim, Jin-Ho;Han, Kyu-Sung
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.26 no.5
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    • pp.201-208
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    • 2016
  • Ceramic pigments, which show good thermal and chemical stabilities, have been applied for various industry with development of digital printing technology. Ceramic inkjet printing has advantages of high efficiency of ink usage and eco-friendly process. Thus, the interest of the ceramic pigments with various function and color including CMYK (cyan, magenta, yellow, black) digital primary color is increasing. Here, we investigated the thermal and chemical stabilities of white ceramic pigment for digital inkjet printing process. The microstructure and crystal structure of MgO, $Al_2O_3$, $MgAl_2O_4$, $CeO_2$ were analyzed, and the stability with glaze were evaluated. In order to evaluate the applicability for digital inkjet printing, the chemical stability of white ceramic pigments at high temperature was investigated by characterization of the mixed color properties with CMYK ceramic pigments after firing process.

Expression of Intercellular Adhesion Molecule-1 in Human Idiopathic Pulmonary Fibrosis (인체 특발성 폐섬유증에서 Intercellular Adhesion Molecule-1의 발현에 관한 연구)

  • Park, Sung-Soo;Shin, Dong-Ho;Kim, Tae-Wha;Lee, Dong-Hoo;Lee, Jung-Hee;Lee, Jung-Dal
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.2
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    • pp.185-191
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    • 1993
  • Background: Intercellular adhesion molecule-1(ICAM-1) is a 90 kD surface glycoprotein, associated with ${\alpha}_L{\beta}_2$ and ${\alpha}_M{\beta}_2$ subunit of integrins, that serve as cell-cell and cell-substratum adhesion molecules and help regulate cellular morphology, differentiation, and proliferation. The adhesion molecules likely play important roles in maintaining the normal structure and function of the lung. ICAM-1 system among many cell adhesion molecules is importantly issuing in the pathogenesis of idiopathic pulmonary fibrosis. Methods : By using $IgG_1$ monoclonal antibody for ICAM-1, we investigated immunohistochemically the expression of ICAM-1 in the formalin-fixed, paraffin-embedded tissue sections of the 3 normal cases and 6 pieces of tissues taken 3 cases with idiopathic pulmonary fibrosis. Results : In the 3 normal cases, the expressions of ICAM-1 were not discernible. Up-regulation of the ICAM-1 expression was showed in the interstitial fibroblast cells of alveolar septa in 5 pieces and proliferated alveolar pneumocytes in 1 piece among 6 pieces of tissues taken 3 cases with idiopathic pulmonary fibrosis. Conclusion : It was concluded from these findings that up-regulation of the ICAM-1 expression may be related to pathogenesis of idiopathic pulmonary fibrosis.

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Error Performance Analysis of DS/CDMA-Trellis Coded QPSK Signal with MRC Diversity Reception in Wireless Data Communication (무선 데이터 통신에서 MRC 다이버시티 수신시의 DS/CDMA-Trellis Coded QPSK 신호의 오율 해석)

  • 노재성;김영철;박기식;강희조;조성준
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.9 no.3
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    • pp.317-329
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    • 1998
  • In this paper, we have analyzed the packet error probability of DS/CDMA-Trellis Coded QPSK modulation signal with MRC(Maximum Ratio Combining) diversity reception in Rician fading, multi-user interferences and multipath channel. And then we have evaluated the performance and capacity of DS/CDMA-Trellis Coded QPSK system using the MRC diversity reception as a function of direct power to indirect power ratio ($K_R$), the number of diversity branch(M), the number of multi-user(U), PN chip rate(PN), the number of multipath channel($L_P$), and packet length(PL). From the results, we know that the coding gain of DS/CDMA-Trellis Coded QPSK system with 2 branch MRC diversity is about 6 dB against uncoded DS/CDMA BPSK system with 2 branch MRC diversity in Rician fading ($K_R=6dB), 5 multi-user interferences, and 3 multipath channel. And, we know that coded QPSK signal designed for the AWGN channel also perform well on a Rician fading channel with MRC diversity reception. Consequently, we expected that proposed system structure is reliable to the wireless data communication system in Rician fading, multi-user interferences, and multipath channel.

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