• Journal of the Korean Magnetics Society
• /
• v.26 no.2
• /
• pp.39-44
• /
• 2016

Determination of the structural, electronic, and magnetic properties of the magnetically doped bismuth-telluride alloys are drawing lots of interest in the fields of the thermoelectric application as well as the research on magnetic interaction and topological insulator. In this study, we performed the first-principles electronic structure calculations within the density functional theory for the Gd doped bismuth-tellurides in order to study its magnetic properties and magnetic phase stability. All-electron FLAPW (full-potential linearized augmented plane-wave) method is employed and the exchange correlation potentials of electrons are treated within the generalized gradient approximation. In order to describe the localized f-electrons of Gd properly, the Hubbard +U term and the spin-orbit coupling of the valence electrons are included in the second variational way. The results show that while the Gd bulk prefers a ferromagnetic phase, the total energy differences between the ferromagnetic and the antiferromagnetic phases of the Gd doped bismuth-telluride alloys are about ~1meV/Gd, indicating that the stable magnetic phase may be changed sensitively depending on the structural change such as defects or strains.

• Journal of Life Science
• /
• v.28 no.4
• /
• pp.488-495
• /
• 2018

The p53 gene plays a critical role in the transcriptional regulation of cellular response to stress, DNA damage, hypoxia, and tumor development. Keeping in mind the recently discovered manifold physiological functions of p53, its involvement in the regulation of cancer is not surprising. In about 50% of all human cancers, inactivation of p53's protein function occurs either through mutations in the gene itself or defects in the mechanisms that activate it. This disorder plays a crucial role in tumor evolution by allowing the evasion of a p53-dependent response. Many recent studies have focused on directly targeting p53 mutants by identifying selective, small molecular compounds to deplete them or to restore their tumor-suppressive function. These small molecules should effectively regulate various interactions while maintaining good drug-like properties. Among them, the discovery of the key p53-negative regulator, MDM2, has led to the design of new small molecule inhibitors that block the interaction between p53 and MDM2. Some of these small molecule compounds have now moved from proof-of-concept studies into clinical trials, with prospects for further, more personalized anti-carcinogenic medicines. Here, we review the structural and functional consequences of wild type and mutant p53 as well as the development of therapeutic agents that directly target this gene, and compounds that inhibit the interaction between it and MDM2.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.30 no.1
• /
• pp.63-70
• /
• 2017

In this paper, a magnetic flux leakage(MFL) based steel bar damage detection was first researched to quantify the signals from damages on the wire rope. Though many researches inspecting damages using a MFL method was proceeded until the present, the researches are at the level that diagnose whether damages are or not. This has limitation to take measures in accordance with the damage level. Thus, a MFL inspection system was modeled using a finite element analysis(FEM) program dealing with electromagnetism problems, and a steel bar specimen was adopted as a ferromagnetic object. Then, an experimental study was also carried out to verify the simulation results with a steel bar which has same damage conditions as the simulation. The MFL signals was nearly not affected by the increase of the inspection velocity, and the magnitudes of the signals are not identical according to the change of the defect width even the defects have same depth. On the basis of the analysis, the signal properties from the damages were extracted to classify the type of damages, and it could be confirmed that classification of damages using extracted signal properties is feasible.

• Geophysics and Geophysical Exploration
• /
• v.21 no.1
• /
• pp.8-14
• /
• 2018

For the purpose of maintenance and prevention of earth fill dams against damage from natural hazards, automatic monitoring through various measuring instruments and resistivity survey has been carried out. Reservoirs and embankments have the structural vulnerability on the agricultural usages since most of them were built more than thirty years ago. The main aim to use monitoring method is to verify the safety and integrity of the dam. Resistivity survey can detect potential weaknesses, such as defective zones, anomalous seepages or internal erosion processes. Permanent resistivity monitoring systems were installed at a reservoir, which daily measurements have been taken every 6 hour. Using monitoring data for one year, anomalous seepage and structural defects were clarified for dam safety. Annual water level fluctuations are around 10 m. During their operation, reservoir dams are subject to a never-ending hydraulic load from the reservoir, which over the years may cause changes in the properties of the inner parts of the dam construction. Detailed analysis of the monitoring results was performed and showed that resistivities at most locations have been very stable over the full monitoring period excluding the effects of water fluctuation and seasons. To investigate the detectability of weak zone using the DC resistivity monitoring, numerical modeling with a simplified model for the drainage at a reservoir dam was also performed. The results showed that the seepage zone near drainage in a reservoir dam could be detected by resistivity response change.

• Journal of Korean Society of Steel Construction
• /
• v.9 no.3 s.32
• /
• pp.287-300
• /
• 1997

In this study, an effective application method of AE technique for the detection of fatigue crack in multi-girder steel bridges has been proposed. The applicability has been examined through the laboratory works with bridge model. The proposed analytical method which evaluates the remaining fatigue lives of structural members may improve the rational determination of the priority of inspection for structural members assuming to have fatigue cracks. Laboratory tests for the application of AE technique to steel girder bridges show that the frequency bands of traffic noise are in the range between 10 show that the frequency bands of traffic noise are in the range between 100~200 kHz and the AE signal raised from fatigue cracks is concentrated around 400~500 kHz. Therefore. R30 sensor is proved to be the most suitable for the detection of cracks in steel girder bridges. A linear proportionality between the crack propagation and the frequency of AE signals has been obtained. In addition, an economic and effective source location method for steel girder bridges was studied through experiments.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.19 no.4
• /
• pp.18-24
• /
• 2015

Non-destructive testing (NDT) methods are widely used in the construction industry to diagnose the defects/strength of the concrete structure. However, it has been reported that the results obtained from NDT are having low reliability. In order to resolve this issue, four kinds of NDT test (ultrasonic velocity measurements by P-wave and S-wave and the impact resonance methods by longitudinal vibration and deformation vibration) were carried out on 180 concrete cylinders made with two kinds of mix proportions. The reliability of the NDT results was analyzed and compared through the measurement of the actual compressive strength of the concrete cylinders. The statistical analysis of the results was revealed that the ultrasonic velocity method by S-wave is having lowest coefficient of variation and also most capable of stable observation. Analytical equations were established to estimate the compressive strength of the concrete from the obtained NDT results by relating the actual compressive strength. Moreover the equation established by the ultrasonic velocity method by S-wave had the highest coefficient of determination. Further studies on the stability of non-destructive testing depending on various mixing conditions will be necessary in the future.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.19 no.1 s.71
• /
• pp.93-103
• /
• 2006

It is absolutely essential that safety assessment of the containment buildings during service life because containment buildings are last barrier to protect radioactive substance due to the accidents. Therefore, this study describes an enhanced degenerated shell finite element(FE) which has been developed for nonlinear FE analysis of reinforced concrete(RC) containment buildings with elasto-plastic material model. For the purpose of the material nonlinear analysis, Drucker-Prager failure criteria is adapted in compression region and material parameters which determine the shape of the failure envelop are derived from biaxial stress tests. Reissner-Mindlin(RM) assumptions are adopted to develop the degenerated shell FE so that transverse shear deformation effects is considered. However, it is found that there are serious defects such as locking phenomena in RM degenerated shell FE since the stiffness matrix has been overestimated in some situations. Therefore, shell formulation is provided in this paper with emphasis on the terms related to the stiffness matrix based on assumed strain method. Finally, the performance of the present shell element to analysis RC containment buildings is tested and demonstrated with several numerical examples. From the numerical tests, the present results show a good agreement with experimental data or other numerical results.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.18 no.2
• /
• pp.394-400
• /
• 2014

In this study, we fabricated ITZO thin films on glass substrates with various RF power from 30 to 60W and investigated the electrical, optical and structural properties. ITZO thin film deposited at 50W exhibited the largest figure of merit ($10.52{\times}10^{-3}{\Omega}^{-1}$) and then its resistivity and sheet resistance were $3.08{\times}10^{-4}{\Omega}-cm$ and $11.41{\Omega}/sq.$, respectively. As results of optical characterization, average transmittance of all ITZO thin films were over 80%. ITZO thin films had amorphous structure regardless of the RF power. The FESEM and AFM results showed that all ITZO thin films have a very smooth surface having no cracks and defects and the film deposited at 50W exhibit the smallest surface roughness of 0.254nm. We found that a amorphous ITZO thin film is a very promising material for replacing ITO in the next display device such as OLED.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.14 no.3
• /
• pp.171-177
• /
• 2010

As concrete structures are exposed to chemical substances, damaged from salt, or progressed to the neutralization, the surface damage of the structures is generated timely fashion, resulting shortened service life. Especially, the sulfate erosion causes rapid surface defects, and the steel skeleton becomes corroded due to the water infiltration, generating stability deterioration of the concrete structure. In this study, the physical characteristics of the acid-resistant mortar with aluminosilicates was investigated in order to resolve problems of the acid resistance, one of the most serious problems of the cement type repair material. As the result of the experiment, the test specimen turned to exhibit almost equivalent physical characteristics with those of concrete sectional repair materials in terms of compressive and bending strengths. As both the cement sectional repair material and the test specimen were immerged in sulfuric acid solution to examine weight changes, the test specimens exhibited only 4% loss of their weights while the cement sectional repair materials reached at the level of 80% or above, proving the excellence acid resistant characteristics of the test specimens. Consequently, the physical characteristics of acid resistant mortar with aluminosilicates were revealed to be superior than those of concrete sectional repair materials. It can be utilized as a sectional repair material where the acidic erosion is anticipated.

• Journal of Distribution Science
• /
• v.12 no.8
• /
• pp.43-54
• /
• 2014

Purpose - This study was based on a theoretical consideration of the structural relationship between the support and control of the franchisor and the satisfaction and strategic response (voice, loyalty, exit, neglect) of the franchisee. First, based on the preceding research, this study systematically organized the type of support and control of the franchisor. Second, the study examined the effects of a franchisor's support and control on the expectancy disconfirmation between affiliated franchisees' expectations before a franchise agreement and performance after operating an affiliated store. Third, the study looked into the effects of expectancy disconfirmation relating to a franchisor's support and control on an affiliated franchisees' general satisfaction. Fourth, this study examined the influence of the general satisfaction of a franchisee on affiliated franchisees' response strategies. Research design, data, and methodology - In this study, the population comprised the nation's franchisors, and the sample comprised franchisees conducting business in Seoul and Gyeonggi-do. A self-administered questionnaire was used; the author and examiner explained the study's parameters to the interviewees in advance, to lessen the rate of rejection of the answers and to maintain reliability. The author distributed 350 copies of the questionnaire and collected 327 copies (93.4%). The author removed 54 copies of the sample, as these copies belonged to franchisees that were not registered by the Fair Trade Commission and/or were thought to have either defects or inadequate answers. The author selected an effective sample of 273 copies to enter data and to do the statistical analysis. Results - Both a reliability analysis and a confirmatory factor analysis were performed to measure reliability and validity, and a structural equation model was used to conduct the hypothesis test and investigate the models. The hypothesis was tested (Table 5). The models had a suitable fit, for instance, χ² = 447.663(df = 212, p = .000), χ²/df = 2.112, GFI = .881, AGFI = .858, RMR = .083, RMSEA = .067, NFI = .932, and CFI = .961. The hypothesis test results were as follows. Hypothesis 1 was accepted (C.R. = -2.339, p = .019). Hypothesis 2 was accepted (C.R. = 15.213, p = .000). Hypothesis 3 was accepted (C.R. = -2.631, p = .006). Hypothesis 4 was accepted (C.R. = 16.271, p = .000). Hypothesis 5 was accepted (C.R. = 2.391, p = .017). Hypothesis 6 was accepted (C.R. = 5.777, p = .000). Hypothesis 7 was accepted (C.R. = 17.153, p = .000). Hypothesis 8 was accepted (C.R. = 24.746, p = .000). Hypothesis 9 was accepted (C.R. = -10.150, p = .000). Hypothesis 10 was accepted (C.R. = -12.124, p = .000). Conclusions - The research results showed that expectations for a franchisor's support and control had a significant influence on expectation disconfirmation in a negative way, whereas the performance of support and control were found to have a significant influence on expectation disconfirmation in a positive way. In addition, the expectation disconfirmation of support and control was found to have a significant influence on satisfaction of franchisees in a positive way. Generally, regarding the research on control, control is found to have a negative influence on the satisfaction of franchisees, but this study proves that control is found to affect it in a positive way through conformity.