• Earthquakes and Structures
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• 제11권4호
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• pp.701-721
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• 2016

Base isolation is a well-established passive strategy for seismic response control of buildings. In this paper, an efficient framework is proposed for reliability-based design optimization (RBDO) of isolated buildings subjected to uncertain earthquakes. The framework uses reduced function evaluations method, as an efficient tool for structural reliability analysis, and an efficient optimization algorithm for optimal structural design. The probability of failure is calculated considering excessive base displacement, superstructure inter-storey drifts, member stress ratios and absolute accelerations of floors of the isolated building as failure events. The behavior of rubber bearing isolators is modeled using nonlinear hysteretic model and the variability of future earthquakes is modeled by applying a probabilistic approach. The effects of pulse component of stochastic near-fault ground motions, fixity-factor of semi-rigid beam-to-column connections, values of isolator parameters, earthquake magnitude and epicentral distance on the performance and safety of semi-rigidly connected base-isolated steel framed buildings are studied. Suitable RBDO examples are solved to illustrate the results of investigations.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2003년도 봄 학술발표회 논문집
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• pp.313-320
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• 2003

The efficient and well organized database is essential for the management of information in every industrial field. In this study, a practical and effective database which can handle 3-D information of steel bridges is built on the basis of a STEP-based data model. The data model of steel bridge information is classified into geometric and non-geometric part and the design information is represented by linking geometric information and life cycle supported non-geometric information. Especially, the shape information is represented by boundary representation method, which is one of the representative methods of solid model information. In this study, ISO/STEP(STandard for the Exchange of product model data) AP203(configuration controlled design) EXPRESS schema is used to represent the shape information of steel bridge. The syntax of EXPRESS schema of developed data model is verified by NIST Expresso - is a tool for parsing and compiling EXPRESS schema. Also, this study verifies the conformance of the data model by applying to the real data of Hannam bridge. Therefore, the constructed database using STEP-based data model of steel bridges can be used effectively in the concurrent engineering point of view with transferring and sharing steel bridge information.

• 한국자동차공학회논문집
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• 제21권1호
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• pp.113-120
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• 2013

This paper proposes a design optimization approach for core of solenoid actuators by combining optimization techniques with the finite element method (FEM). A solenoid is an important element part which hydraulically controls a transmission system, etc. The demanded feature of the solenoid is that it performs an electromagnetic force output being constant regardless of the stroke and being proportional to coil current. The plunger compresses a spring with a minimum force of 12 N over an 1.7 mm travel. The orthogonal array, analysis of variance (ANOVA) techniques and response surface optimization, are employed to determine the main effects and their optimal design variables. The methodology is demonstrated as a optimization tool for the core design of a solenoid actuator.

• 한국전산구조공학회논문집
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• 제16권1호
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• pp.1-8
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• 2003

위상최적설계는 개념설계에 적합하며, 제품의 설계에서 사용되어지고 있다. 전통적인 위상최적화는 균질화법과 최적조건법을 사용해 왔다. 균질화법은 구멍으로 구성된 구조물과 강성행렬사이의 관계를 연결해주는데 사용되며, 최적조건법은 부피분율을 유지하며 설계변수의 개선에 사용되어진다. 전통적인 위상최적설계는 수렴성이 좋은 장점은 있지만 수렴시간이 많이 걸린다는 단점이 있었다. 이 문제를 해결하는 하나의 방법으로 평균 응력량을 기준으로 요소를 제거하는 요소제거법을 제시하였다. 예제에서 수렴속도가 향상됨을 알 수 있었다.

• Applied Microscopy
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• 제51권
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• pp.13.1-13.7
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• 2021

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has arisen as a global pandemic affecting the respiratory system showing acute respiratory distress syndrome (ARDS). However, there is no targeted therapeutic agent yet and due to the growing cases of infections and the rising death tolls, discovery of the possible drug is the need of the hour. In general, the study for discovering therapeutic agent for SARS-CoV-2 is largely focused on large-scale screening with fragment-based drug discovery (FBDD). With the recent advancement in cryo-electron microscopy (Cryo-EM), it has become one of the widely used tools in structural biology. It is effective in investigating the structure of numerous proteins in high-resolution and also had an intense influence on drug discovery, determining the binding reaction and regulation of known drugs as well as leading the design and development of new drug candidates. Here, we review the application of cryo-EM in a structure-based drug design (SBDD) and in silico screening of the recently acquired FBDD in SARS-CoV-2. Such insights will help deliver better understanding in the procurement of the effective remedial solution for this pandemic.

• Structural Engineering and Mechanics
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• 제51권1호
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• pp.67-88
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• 2014

It is shown that topology optimization is a valuable tool for the design of bridge girders. This paper is a follow-up to (Kuty${\l}$owski and Rasiak 2014) and it includes an analysis of truss members' outer dimensions dictated by the standards. Moreover, a frame bridge girder mapped from a selected topology is compared with a typical frame girder on the basis of (Kuty${\l}$owski and Rasiak 2014). The analysis shows that topology optimization by means of the proposed algorithm yields a topology from which one can map a frame bridge girder requiring less material for its construction than the typical frame girder currently used in bridge construction.

• Structural Engineering and Mechanics
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• 제51권1호
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• pp.39-66
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• 2014

This study deals with the design of bridge girder structures and consists of two parts. In the first part an optimal bridge girder topology is determined using a software based on structure compliance minimization with constraints imposed on the body mass, developed by the authors. In the second part, an original way in which the topology is mapped into a bridge girder structure is shown. Additionally, a method of converting the thickness of the bars obtained using the topology optimization procedure into cross sections is introduced. Moreover, stresses and material consumption for a girder design obtained through topology optimization and a typical truss girder are compared. Concluding, this paper shows that topology optimization is a good tool for obtaining optimal bridge girder designs.

• Structural Engineering and Mechanics
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• 제30권1호
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• pp.77-97
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• 2008

In this paper, a strut-and-tie model approach has been proposed to directly calculate the amount of reinforcements in deep beams, and the force transfer mechanisms for this approach were investigated using linear finite element analysis. The proposed strut-and-tie model provides quite similar force transfer mechanisms to the results of linear finite element analysis for the 28 deep beams. The load-carrying capacities calculated from the proposed method are both accurate and conservative with little scatter or trends for the 214 deep beams. The deep beams have different concrete strengths including high-strength, various combinations of web reinforcements, and wide range of and a/d ratios. Good accuracy was also obtained using VecTor2, nonlinear finite element analysis tool based on the Modified Compression Field Theory. Since the proposed method provides a safe and reliable means for design of deep beams, this can serve to improve design provisions in future adjustments and development of design guidelines.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2000년도 추계학술대회 논문집
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• pp.969-971
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• 2000

In this paper, shortening of product life cycle and wide disposal of consumer product have given rise to many environmental problems, it needs to propose module design principle for saving of disassembly cost and reusing of used part and subassembly. To analyze characteristics of module for recycling, materials and function of part and subassembly must be classified. In disassembly process, a unit operation can be grasped for disassembly function, worker, tool and sorting process. As a result of applying module design principle, simpler structure and reduced structural interference can be realized for product structure. For disassembly, simpler disassembly and quicker disassembly can be obtained for recycling.

• 대한기계학회논문집A
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• 제25권4호
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• pp.610-618
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• 2001

Pantograph, which collects current from cartenary system, is one of the important parts of high-speed train. Kinematic analysis is one of the key technologies for pantograph design and includes joint trajectories, reaction forces, and the required moment of main shaft calculations. The kinematic analysis, however, is very complex and time-consuming process. In this study PC based pantograph kinematic analysis software using graphical user interface tool was developed for the easy evaluations of kinematic characteristics necessary in pantograph design process.